KEGG   ENZYME: 2.4.2.47
Entry
EC 2.4.2.47                 Enzyme                                 

Name
arabinofuranan 3-O-arabinosyltransferase;
AftC
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
Sysname
alpha-(1->5)-arabinofuranan:trans,octacis-decaprenylphospho-beta-D-arabinofuranose 3-O-alpha-D-arabinofuranosyltransferase
Reaction(IUBMB)
Adds an alpha-D-arabinofuranosyl group from trans,octacis-decaprenylphospho-beta-D-arabinofuranose at the 3-O-position of an alpha-(1->5)-arabinofuranan chain attached to a beta-(1->5)-galactofuranan chain
Comment
Isolated from Mycobacterium smegmatis. Involved in the formation of the cell wall in mycobacteria.
History
EC 2.4.2.47 created 2012
Pathway
ec00571  Lipoarabinomannan (LAM) biosynthesis
ec00572  Arabinogalactan biosynthesis - Mycobacterium
Orthology
K16647  arabinofuranan 3-O-arabinosyltransferase
Genes
LJR: NCTC11533_01968
PPNO: DA70_07255
PPNM: LV28_23420
PRB: X636_19420
PSPU: NA29_19460
PFG: AB870_19545
PCAY: FRD00_08085
SIX: BSY16_1928
RHN: AMJ98_CH03635
REZ: AMJ99_CH03687
RHT: NT26_0804
RPD: RPD_2994
MTU: Rv2673(aftC)
MTV: RVBD_2673
MTC: MT2747
MRA: MRA_2701
MTUR: CFBS_2825
MTD: UDA_2673
MTUB: MT7199_2705(aftC)
MTUC: J113_18595
MTUE: J114_14270
MTUH: I917_18775
MTUL: TBHG_02609
MTUT: HKBT1_2816
MTUU: HKBT2_2819
MBO: BQ2027_MB2692(aftc)
MBB: BCG_2686
MBT: JTY_2680
MBX: BCGT_2505
MAF: MAF_26770
MMIC: RN08_2957
MLE: ML1338
MLB: MLBr01338
MPA: MAP_2793
MAO: MAP4_1019
MAVI: RC58_05015
MAVU: RE97_05010
MAV: MAV_3565
MIT: OCO_33990
MIA: OCU_34010
MID: MIP_05118
MYO: OEM_34370
MIR: OCQ_35210
MLP: MLM_1549
MUL: MUL_3307
MMC: Mmcs_2217
MKM: Mkms_2263
MJL: Mjls_2206
MMI: MMAR_2043
MMM: W7S_17000
MHAD: B586_14375
MSHG: MSG_01857
MSTO: MSTO_15440
MNV: MNVI_34640(aftC)
MCOO: MCOO_02790
MBAI: MB901379_01864(aftC)
MSEO: MSEO_06560
MVA: Mvan_2488
MGI: Mflv_3915
MVQ: MYVA_2378
MHAS: MHAS_02308(aftC)
MMAG: MMAD_23810
MMOR: MMOR_39690
MAIC: MAIC_21020
MALV: MALV_12200
MARZ: MARA_15870
MGAD: MGAD_14410
MHEV: MHEL_45970
MSAR: MSAR_33900
MANY: MANY_07510
MAUB: MAUB_57060
MPOF: MPOR_28000
MAB: MAB_2978
MABB: MASS_2913
MCHE: BB28_14985
MSTE: MSTE_02947
MMIN: MMIN_01260(aftC)
MHIB: MHIB_18700(aftC)
ASD: AS9A_1785
CGL: NCgl1822(Cgl1897)
CGB: cg2077
CGU: WA5_1822
CGT: cgR_1726
CGM: cgp_2077
CGJ: AR0_08925
CEF: CE1790
CDI: DIP1690
CDP: CD241_1623(aftC)
CDH: CDB402_1581(aftC)
CDT: CDHC01_1626(aftC)
CDE: CDHC02_1560(aftC)
CDR: CDHC03_1588(aftC)
CDA: CDHC04_1588(aftC)
CDZ: CD31A_1697(aftC)
CDB: CDBH8_1664(aftC)
CDS: CDC7B_1674(aftC)
CDD: CDCE8392_1586(aftC)
CDW: CDPW8_1682(aftC)
CDV: CDVA01_1550(aftC)
CDIP: ERS451417_01703(aftC)
CJK: jk1071
CUR: cu0918
CUA: CU7111_0904(aftC)
CAR: cauri_1439(aftC)
CPSE: CPTA_01768
CPSU: CPTB_01995
CPSF: CPTC_01759
CRD: CRES_1163(aftC)
CUL: CULC22_01304(aftC)
CUC: CULC809_01290(aftC)
CUE: CULC0102_1419(aftC)
CVA: CVAR_1564(aftC)
CTER: A606_06205
CGY: CGLY_08085(aftC)
COA: DR71_2114
CKU: UL82_05965(aftC)
CSP: WM42_2540
CAMG: CAMM_06160
CMIN: NCTC10288_01062(aftC)
CPRE: Csp1_12860(aftC)
CSUR: N24_1964(aftC)
NFA: NFA_37340
NNO: NONO_c52550(aftC)
NSR: NS506_05834(aftC)
RER: RER_28550(aftC)
REY: O5Y_13155
ROP: ROP_68480(aftC)
REQ: REQ_20660
RHB: NY08_1194
RRT: 4535765_02099(aftC_1) 4535765_02476(aftC_2)
RCR: NCTC10994_00766(aftC)
GBR: Gbro_2268
GOR: KTR9_2184
GOM: D7316_00788(aftC)
TPR: Tpau_1896
SRT: Srot_1649
SCO: SCO4733(SC6G4.11)
SCT: SCAT_3624
STRM: M444_20855
SLE: sle_29320(sle_29320)
STRD: NI25_15280
SALF: SMD44_05257(aftC)
SALJ: SMD11_4226(aftC)
SFK: KY5_4826
TTF: THTE_2349
HSW: Hsw_3686
DKA: DKAM_1443
 » show all
Reference
1  [PMID:18627460]
  Authors
Birch HL, Alderwick LJ, Bhatt A, Rittmann D, Krumbach K, Singh A, Bai Y, Lowary TL, Eggeling L, Besra GS
  Title
Biosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferase.
  Journal
Mol Microbiol 69:1191-206 (2008)
DOI:10.1111/j.1365-2958.2008.06354.x
  Sequence
[cgl:NCgl1822] [msm:MSMEG_2785] [mtu:Rv2673]
Reference
2  [PMID:21595486]
  Authors
Zhang J, Angala SK, Pramanik PK, Li K, Crick DC, Liav A, Jozwiak A, Swiezewska E, Jackson M, Chatterjee D
  Title
Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors.
  Journal
ACS Chem Biol 6:819-28 (2011)
DOI:10.1021/cb200091m
  Sequence
[mtu:Rv2673]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.2.47
IUBMB Enzyme Nomenclature: 2.4.2.47
ExPASy - ENZYME nomenclature database: 2.4.2.47
BRENDA, the Enzyme Database: 2.4.2.47

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