KEGG   ENZYME: 2.4.2.48
Entry
EC 2.4.2.48                 Enzyme                                 
Name
tRNA-guanine15 transglycosylase;
tRNA transglycosylase (ambiguous);
transfer ribonucleate glycosyltransferase (ambiguous);
tRNA guanine15 transglycosidase;
TGT (ambiguous);
transfer ribonucleic acid guanine15 transglycosylase
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
Sysname
tRNA-guanine15:7-cyano-7-carbaguanine tRNA-D-ribosyltransferase
Reaction(IUBMB)
guanine15 in tRNA + 7-cyano-7-carbaguanine = 7-cyano-7-carbaguanine15 in tRNA + guanine
Substrate
guanine15 in tRNA;
7-cyano-7-carbaguanine [CPD:C15996]
Product
7-cyano-7-carbaguanine15 in tRNA;
guanine [CPD:C00242]
Comment
Archaeal tRNAs contain the modified nucleoside archaeosine at position 15. This archaeal enzyme catalyses the exchange of guanine at position 15 of tRNA with the base preQ0, which is ultimately modified to form the nucleoside archaeosine (cf. EC 2.6.1.97) [1].
History
EC 2.4.2.48 created 2012
Orthology
K18779  7-cyano-7-deazaguanine tRNA-ribosyltransferase
Genes
PPMPPSC2_01065(tgtC)
PPOPPM_0191(tgtC)
PVOPVOR_07275
PLWD5F53_24590
CTHCthe_3185
CTXClo1313_0734
CYJCyan7822_2821
PAGHNIES204_27070
CTMCabther_A0932
MJAMJ_0436
MFEMefer_0980
MVUMetvu_0178
MFSMFS40622_1703
MIFMetin_0864
MJHJH146_1349
MESGMLAUSG7_1612(tgtA)
MESAMLASG1_1060(tgtA)
MIGMetig_0611
MMPMMP0610(tgtA)
MMQMmarC5_0996
MMXMmarC6_0282
MMZMmarC7_1632
MMDGYY_03425
MMAKMMKA1_06590(tgtA)
MMAOMMOS7_06540(tgtA)
MMADMMJJ_03740(tgt)
MAEMaeo_0878
MVNMevan_1482
MVOMvol_0802
MOKMetok_1508
METFCFE53_03650
MTHMTH_176
MMGMTBMA_c06290(tgt) MTBMA_c08930
MWOMWSIV6_0592(tgtA)
MTEEMTTB_08360
METCMTCT_0143
METEtca_00160(tgt)
METZMETMT2_0639
METKFVF72_01400(tgtA)
MTHMFZP57_02815(tgtA)
METJFZP68_07845(tgtA)
MSTMsp_0520
METBAW729_03950
MRUmru_1512(tgtA2)
MSIMsm_1557
MEBAbm4_1021(tgtA)
MMILsm9_1475(tgtA1)
MEYETL18_06780
MOLYLM1_1008
MAROMarbSA_20160
METVK4897_08655(tgtA)
MELMetbo_0966
MEWMSWAN_1284
METHMBMB1_0938(tgtA) MBMB1_1276
MFCBRM9_0492(tgtA1) BRM9_1112(tgtA2)
MFIDSM1535_0473 DSM1535_1766(tgtA)
MCUBMCBB_1229(tgtA)
MSUBBK009_03940
METNBK008_11635
METTCIT01_08460 CIT01_09780
METOCIT02_01275 CIT02_11675
MEMEHYG87_10175(tgtA)
MFVMfer_1280
MKAMK0188(tgt)
AFUAF_0588
AFGAFULGI_00006630
APOArcpr_1823
AVEArcve_0758
ASTAsulf_00167
FPLFerp_1811
GACGACE_2025
GAHGAH_00619
PFUPF1046
PFIPFC_04465
PHOPH1116(PH1116)
PABPAB0740(tgtA)
PYNPNA2_1792
PYAPYCH_06100
PYSPy04_1170
PYCTQ32_06140
TKOTK0760
TONTON_0617
TGATGAM_1141(arcTGT)
TSITSIB_0093
TBATERMP_00914
THEGQS_01945
THATAM4_2111
THMCL1_0051
TLTOCC_06816
THSTES1_0575
TNUBD01_0733
TEUTEU_07720
TGYX802_02830 X802_08615
THVADU37_CDS00120
TCHCHITON_1477
TPEPA0127_01270
TPIEA7C91_09125
TGGA3K92_05420
TCEA3L02_08200
TBSA3L01_03790
THHCDI07_03710
TSLA3L11_07780
TTDA3L14_05580 A3L14_07970
TPRFA3L09_07825
TRLA3L10_02760
TPAFA3L08_07040
THYA3L12_05185
TICFH039_09455(tgtA)
TCQTIRI35C_1006(tgtA)
THEMFPV09_00255(tgtA)
THEIK1720_03540(tgtA)
PPACPAP_07820
MBAMbar_A1088
MBYMSBRM_3344
MBWMSBRW_3634
MBARMSBR2_3297
MBAKMSBR3_3298
MACMA_4419(tgt)
MMAMM_1101
MMAZMmTuc01_1140
MMJMSMAS_0201
MMACMSMAC_0206
MVCMSVAZ_0184
MEKMSKOL_0178
MLSMSLAZ_2930
METMMSMTP_0234
MEFMSWH1_0500
MEQMSWHS_0512
MSJMSSAC_4105
MSZMSSIH_3641
MSWMSSIT_3696
MTHRMSTHT_1729
MTHEMSTHC_1559
MHORMSHOH_0253
MFZAOB57_007830(tgtA)
MBUMbur_0941(tgtA)
MMETMCMEM_1443
MELOJ7W08_05930(tgtA)
MMHMmah_0673
MHAZBHR79_10235
MEVMetev_1733
MZHMzhil_0233
MPYMpsy_1469
MZIHWN40_01420(tgtA)
MHZMetho_0237
MTPMthe_1660
MCJMCON_0339
MHIMhar_0739
MHUMhun_1120
MRTJKHC33_08525(tgtA)
MLAMlab_1207
MEMMemar_1287
MBGBN140_2027(tgt3)
MEMAMMAB1_2627(tgtA)
MCHKMchiMG62_14730
MPIMpet_2091
MBNMboo_1313
MFOMetfor_1670
MPLMpal_1831
MPDMCP_1180(tgtA)
MEZMtc_1497(tgtA)
RCIRCIX2688(tgt-2)
HALVNG_1959G(tgtA1)
HSLOE_3749R(tgtA)
HDLHALDL1_14740
HHBHhub_3276(tgtA)
HAGSJT689_09220(tgtA)
HABOJRZ79_07630(tgtA)
HNOLT974_13175(tgtA)
HLULT972_01610(tgtA)
HANRLJ422_07885(tgtA)
HJEHacjB3_04665
HALHHTSR_1954(tgtA1)
HHSRHSR6_2029(tgtA1)
HSUHLASF_1961(tgtA1)
HSFHLASA_1947(tgtA1)
SALRFQU85_06365(tgtA) FQU85_13150
HALREFA46_002245(tgtA)
HARAAArcS_1165(tgt) AArcS_1595 AArcS_1597(tgt2)
HAADMW046_01310(tgtA)
HALXM0R89_03445(tgtA)
HAXZM0R88_03655(tgtA)
HMArrnAC3258(tgt)
HHIHAH_0503(tgt1)
HHNHISP_02605
HABSG26_10395
HTABVU17_02475
HALJG9465_17745(tgtA)
HSINKDQ40_11020(tgtA) KDQ40_22875
NPHNP_2508A(tgtA)
NMONmlp_3669(tgtA)
NHOHWV23_14775(tgtA)
NSALHWV07_18015(tgtA)
HUTHuta_2181
HTIHTIA_2061
HALAHrd1104_02875(tgtA)
HMUHmuk_1434
HALZE5139_10325(tgtA)
HALLLC1Hm_0973(tgtA)
HAZPGBQ70_10320(tgtA)
HALIBV210_11915
HSNDV733_01170 DV733_01180 DV733_03190
HDSHSR122_2696(tgt)
HRRHZS55_06675(tgtA)
HPELHZS54_07205(tgtA)
HLTI7X12_06790(tgtA)
HARCHARCEL1_04695 HARCEL1_12085 HARCEL1_12905
HDOMUK72_01460(tgtA)
HVOHVO_2001(tgtA1)
HMEHFX_2097(tgt)
HGIABY42_09780
HALEG3A49_13005(tgtA)
HBOHbor_06020
HAQDU484_04520
HAJDU500_04935
HAERDU502_02835(tgtA)
HRAEI982_10760(tgtA) EI982_16750 EI982_16760
HLMDV707_02085
HALMFCF25_00300 FCF25_00315 FCF25_02275(tgtA)
HLAHlac_2160
HALPDOS48_10425
HALBEKH57_05930(tgtA)
HEZZEO776_06595(tgtA)
HALQHrr1229_011360(tgtA)
HSSJ7656_10015(tgtA) J7656_11510 J7656_11520
HSAIHPS36_00365(tgtA)
HAZZKI388_07410
SRUBC2R22_19070
HAEhalTADL_2549
HALNB4589_007885(tgtA)
HALGHUG10_09565(tgtA)
HALUHUG12_06155(tgtA)
HMPK6T50_07365(tgtA)
HREK6T36_07135(tgtA)
HRMK6T25_08640(tgtA)
HACBHbl1158_13730(tgtA)
HDFAArcSl_0263(tgtA)
HAHHalar_1993
HTUHtur_0719
HDABB347_00680
HSALJMJ58_05490(tgtA)
HLOJ0X27_03265(tgtA) J0X27_05370
HAKZJ0X25_10800(tgtA) J0X25_12290
NMGNmag_2676(tgtA)
HXAHalxa_3588
NATNJ7G_3961
NPENatpe_3147
NVRFEJ81_14805(tgtA)
NPLFGF80_12285 FGF80_13845(tgtA)
NAYHYG81_13910(tgtA)
HALYHYG82_18350 HYG82_18360 HYG82_20000(tgtA)
HJTDVR14_05860
NGENatgr_1056
HRUHalru_0675
NOUNatoc_0816
SALIL593_08885
SAIMK0C01_07490(tgtA)
HLRHALLA_08145
HLCCHINAEXTREME01480
NAJB1756_06790
NAGAArcMg_0720
NANAArc1_2903
NBGDV706_03675
NASGCU68_09815(tgtA) GCU68_16940
SAWLNGM29_01750(tgtA) NGM29_19440
MELUMTLP_07920
MEAMMU439_02540(tgtA)
TACTa1493
TVOTVG1580555(TVG1580555)
PTOPTO0454
FACFACI_IFERC01G0857
FAIFAD_1747
CDIVCPM_0489
TARTALC_00617
MAXMMALV_05930
MERMMINT_14750
MEARMpt1_c02640(tgtA1)
MEUZKRP56_05120(tgtA)
MARCAR505_0637
ABIAboo_0570
ACFAciM339_0479
APEAPE_2017
ACJACAM_1266
SMRSmar_0911
SHCShell_1554
IHOIgni_0478 Igni_0817
IISEYM_03435 EYM_04515
DKADKAM_1258
DFDDesfe_1359
DMUDesmu_1248
TAGTagg_1283
IAGIgag_0098
THGTCELL_0281
HBUHbut_0469
PFMPyrfu_0098 Pyrfu_0491
PDLPyrde_0066 Pyrde_1365
STOSTK_03270(tgtA)
SOHD1869_01245(tgtA)
SSOSSO0274(tgtA)
SOLSsol_1251
SSOASULA_1292(tgtA)
SSOLSULB_1293(tgtA)
SSOFSULC_1291(tgtA)
SSHIJ5U23_03193
SCASSACC_01920
SAISaci_0659
SACNSacN8_03185
SACRSacRon12I_03175
SACSSUSAZ_02975
SISLS215_1966
SIAM1425_1857
SIMM1627_1944
SIDM164_1874
SIYYG5714_1943
SINYN1551_0979
SIILD85_2086
SIHSiH_1803
SIRSiRe_1723
SICSiL_1717
SULABFU36_04805
SULEGFS03_10220(tgtA)
SULOGFS33_02035(tgtA)
SULLEWF20_02695(tgtA)
MSEMsed_2272
MCNMcup_2018
MHKDFR87_06845(tgtA)
MPRUDFR88_06835
MTENGWK48_05310(tgtA)
MJNMjAS7_0566
MEMJMJ1HA_2597
AHOAhos_0803
AMANB6F84_07480
ABRIDFR85_07390(tgtA)
ASULDFR86_06535(tgtA)
AAMBD1866_11860(tgtA)
ACIHHS5_21770
SACDHS1genome_0368
SAZOD1868_01985(tgtA)
CSTYKN1_18910
STEPIC006_1769
SAHSHS7_08210
PAIPAE0777
PISPisl_1072 Pisl_2003
PCLPcal_2149
PASPars_0033 Pars_2160
PYRP186_1074
POGPogu_2457 Pogu_2729
TNETneu_0030
PYWPYWP30_00035 PYWP30_02110
CMACmaq_0024
TTNTTX_1934(tgtA) TTX_1975
TUZTUZN_1496 TUZN_1566
VDIVdis_1864
VMOVMUT_0301
TPETpen_0356
THBN186_02800
TCBTCARB_1628
THELIG193_05765(tgtA)
ASCASAC_0308
CLGCalag_1247
FFOFFONT_1048
NMRNmar_1536
NIRNSED_08445
NKRNKOR_08355
NIDNPIRD3C_0009(tgtA)
NINNADRNF5_0355(tgtA)
NIWNisw_06235(tgtA)
NCLC5F47_08050
NOXC5F49_07935
NUEC5F50_11275
NIPNsoK4_00600(tgtA)
NCTNMSP_0225(tgtA_1)
NICDSQ20_08960
CSYCENSYa_1646
NGANgar_c32140(tgtA)
NVNNVIE_022530(tgtA)
NEVNTE_03307
TAANMY3_00824(tgt)
NFNNFRAN_1814(tgt)
NCVNCAV_0711(tgtA)
CSUCSUB_C1315
NBVT478_1256
TAHSU86_004490
NIUDSQ19_01565
NDVNDEV_0261(tgtA)
CCAINAS2_1317
KCRKcr_1361
BARCAOA65_1371(tgtA_1)
BARBAOA66_1126(tgtA_2)
NEQNEQ124
LOKILokiarch_50690(tgtA_2) Lokiarch_52540(tgtA_3)
PSYTDSAG12_00760(tgtA_2)
 » show all
Reference
1  [PMID:10862614]
  Authors
Bai Y, Fox DT, Lacy JA, Van Lanen SG, Iwata-Reuyl D
  Title
Hypermodification of tRNA in Thermophilic archaea. Cloning, overexpression, and characterization of tRNA-guanine transglycosylase from Methanococcus jannaschii.
  Journal
J Biol Chem 275:28731-8 (2000)
DOI:10.1074/jbc.M002174200
  Sequence
[mja:MJ_0436]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.2.48
IUBMB Enzyme Nomenclature: 2.4.2.48
ExPASy - ENZYME nomenclature database: 2.4.2.48
BRENDA, the Enzyme Database: 2.4.2.48

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