KEGG   ENZYME: 2.4.99.16
Entry
EC 2.4.99.16                Enzyme                                 

Name
starch synthase (maltosyl-transferring);
alpha1,4-glucan:maltose-1-P maltosyltransferase;
GMPMT
Class
Transferases;
Glycosyltransferases;
Transferring other glycosyl groups
Sysname
alpha-maltose 1-phosphate:(1->4)-alpha-D-glucan 4-alpha-D-maltosyltransferase
Reaction(IUBMB)
alpha-maltose 1-phosphate + [(1->4)-alpha-D-glucosyl]n = phosphate + [(1->4)-alpha-D-glucosyl]n+2 [RN:R09994]
Reaction(KEGG)
R09994
Substrate
alpha-maltose 1-phosphate [CPD:C20237];
[(1->4)-alpha-D-glucosyl]n
Product
phosphate [CPD:C00009];
[(1->4)-alpha-D-glucosyl]n+2
Comment
The enzyme from the bacterium Mycobacterium smegmatis is specific for maltose. It has no activity with alpha-D-glucose.
History
EC 2.4.99.16 created 2012
Pathway
ec00500  Starch and sucrose metabolism
ec01100  Metabolic pathways
Orthology
K16147  starch synthase (maltosyl-transferring)
Genes
XCC: XCC0133
XCB: XC_0141
XCA: xcc-b100_0148
XCP: XCR_4406
XCV: XCV0139
XAX: XACM_0139
XAC: XAC0154
XCI: XCAW_00548
XCT: J151_00271
XCJ: J158_00269
XOM: XOO0175(XOO0175)
XOO: XOO0197(AmyA)
XOP: PXO_03667
XOR: XOC_0249
XPH: XppCFBP6546_11155(XppCFBP6546P_11155)
PSD: DSC_13535
RBD: ALSL_1673
PAE: PA2151
PAEV: N297_2221
PAEI: N296_2221
PAEP: PA1S_14940
PAEM: U769_14535
PAEL: T223_16220
PAEG: AI22_18830
PAEC: M802_2218
PAEO: M801_2220
PMY: Pmen_2295
PMK: MDS_2437
PCQ: PcP3B5_27320(glgE2)
PPU: PP_4060(glgE)
PPF: Pput_1783
PPT: PPS_3465
PPI: YSA_08674
PPX: T1E_3318(aam1)
PPUH: B479_17225
PPUT: L483_22670
PPUN: PP4_17000
PPUD: DW66_3911
PMON: X969_16525
PMOT: X970_16170
PSB: Psyr_2489
PSYR: N018_14830
PVD: CFBP1590__2623(glgE)
PFL: PFL_2872
PPRC: PFLCHA0_c29180(aam)
PPRO: PPC_2904
PFO: Pfl01_2534(pep1B)
PFS: PFLU_2761
PFB: VO64_0091
PMAN: OU5_0596
PFW: PF1751_v1c24250(glgE)
PEN: PSEEN2044
PSA: PST_2154
PSTT: CH92_11410
PSES: PSCI_3997
PSEM: TO66_14305
PSEC: CCOS191_3457(glgE)
PSOS: POS17_3204
PANR: A7J50_2640
PSIL: PMA3_14965
PALL: UYA_12735
POJ: PtoMrB4_31750(glgE)
AVN: Avin_28010(glgE)
AVL: AvCA_28010(glgE)
AVD: AvCA6_28010(glgE)
ACX: Achr_19650(glgE)
PIN: Ping_1954
LJR: NCTC11533_01535(glgE2)
MCA: MCA2605
MAH: MEALZ_3500(amyA)
MMAI: sS8_2330
THIP: N838_18950
SVA: SVA_1495
RSO: RSp0241
RSL: RPSI07_mp0203(glgE)
RSN: RSPO_m00239(glgE)
RSE: F504_3681
RSY: RSUY_35760(glgE1)
RPI: Rpic_3939
REH: H16_B1557(h16_B1557)
CNC: CNE_2c15570(aam)
CTI: RALTA_B1364(glgE)
CGD: CR3_4209(glgE)
BMAL: DM55_2797
BMAQ: DM76_2780
BMAI: DM57_2893
BMAF: DM51_592
BMAZ: BM44_2412
BMAB: BM45_1977
BPS: BPSL2074
BPSE: BDL_613
BPSM: BBQ_1953
BPSU: BBN_2079
BPSD: BBX_2552
BPK: BBK_117
BPSH: DR55_3194
BPSA: BBU_789
BPSO: X996_2801
BUT: X994_1258
BVE: AK36_5297
BCN: Bcen_1330
BCEN: DM39_7063
BCEW: DM40_5154
BCEO: I35_7567
BAM: Bamb_5590
BMU: Bmul_5491
BMK: DM80_5711
BMUL: NP80_5560
BCED: DM42_7082
BDL: AK34_5082
BUB: BW23_5000
BLAT: WK25_16445
BTEI: WS51_27175
BSEM: WJ12_16870
BPSL: WS57_15695
BMEC: WJ16_18150
BGU: KS03_4383
BGO: BM43_4568
BUK: MYA_5327
BXE: Bxe_B2861
BXB: DR64_5190
BPH: Bphy_4393
BFN: OI25_5277
PPUL: RO07_21225
PLG: NCTC10937_02796(glgE2)
CABA: SBC2_56500(glgE)
BBR: BB2862
BPT: Bpet2371
AXX: ERS451415_04236(glgE2)
ODI: ODI_R0753
RFR: Rfer_2161
AAV: Aave_2023
AAA: Acav_3136
ACRA: BSY15_1578
VPD: VAPA_1c21100(glgE)
HYR: BSY239_10
PBH: AAW51_0802(glgE)
MFA: Mfla_1419
MEP: MPQ_2503(amyA)
URU: DSM104443_02106(glgE)
EBA: ebA7002
ABRE: pbN1_34250(glgE)
AZO: azo1726(pep1)
AOA: dqs_1876
GBM: Gbem_0135
GEO: Geob_1218
GEM: GM21_0116
GEB: GM18_0117
GBN: GEOBRER4_01200(glgE)
DRT: Dret_0034
DOL: Dole_0851
DAL: Dalk_0887
DALK: DSCA_49270
MXA: MXAN_3685
HOH: Hoch_4097
MES: Meso_2679
PLA: Plav_0540
AVI: Avi_5565
REL: REMIM1_PF00642(glgE)
REP: IE4803_PC00284(glgE)
REI: IE4771_PD00283(glgE)
RLE: pRL120708
RLG: Rleg_5097
RGA: RGR602_PC00715(glgE)
RHN: AMJ98_PE00369(glgE)
RPHA: AMC79_PD00504(glgE)
RHX: AMK02_PD00228(glgE)
RHK: Kim5_PC00266(glgE)
REZ: AMJ99_PD00369(glgE)
NEN: NCHU2750_04900(glgE)
RHT: NT26_2209
BJA: blr6766(blr6766)
BRS: S23_15470
BRAD: BF49_4885
BARH: WN72_38710
BVZ: BRAD3257_2489(glgE)
RPA: RPA3642
RPB: RPB_1884
RPC: RPC_3678
RPD: RPD_3482
RPE: RPE_3716
RPT: Rpal_4163
NWI: Nwi_1209
NHA: Nham_1466
OCA: OCAR_7063
VGO: GJW-30_1_02170(glgE2)
MDI: METDI3475
MEX: Mext_2712
MCH: Mchl_2939
MPO: Mpop_2834
MET: M446_6808
MNO: Mnod_7547
MOR: MOC_1983
META: Y590_13035
MAQU: Maq22A_c04000(amyA)
BBAR: RHAL1_02682(glgE)
MCG: GL4_0144
RSP: RSP_2445
LVS: LOKVESSMR4R_03644(glgE1)
SECH: B18_22685
ALB: AEB_P2570
ACR: Acry_2934
SHUM: STHU_20630
SVC: STVA_35440(glgE)
RRU: Rru_A1604
RRF: F11_08275
RCE: RC1_0519
TMO: TMO_a0215(aam1)
PRI: PRIO_4932
HMO: HM1_1304
HCV: FTV88_0032(amyA)
ABRA: BN85310480
MBJ: KQ51_00936(glgE)
MTU: Rv1327c(glgE)
MTC: MT1369
MRA: MRA_1335(glgE)
MTUR: CFBS_1412(glgE)
MTO: MTCTRI2_1364(glgE)
MTD: UDA_1327c(glgE)
MTN: ERDMAN_1487(glgE)
MTUC: J113_09240
MTUE: J114_07140
MTUH: I917_09435
MTUL: TBHG_01314
MTUT: HKBT1_1411(glgE)
MTUU: HKBT2_1417(glgE)
MTQ: HKBS1_1415(glgE)
MBO: BQ2027_MB1362C(glgE)
MBB: BCG_1389c(glgE)
MBT: JTY_1363(glgE)
MBM: BCGMEX_1361c(glgE)
MBX: BCGT_1162
MAF: MAF_13510(glgE)
MMIC: RN08_1486
MCE: MCAN_13451(glgE)
MCQ: BN44_11492(glgE)
MCV: BN43_30425(glgE)
MCX: BN42_21235(glgE)
MCZ: BN45_30409(glgE)
MPA: MAP_2433
MAO: MAP4_1390
MAVI: RC58_06895
MAV: MAV_1547
MIT: OCO_16100
MIA: OCU_16300
MID: MIP_02222
MYO: OEM_14140
MIR: OCQ_13780
MLP: MLM_2907
MUL: MUL_3935
MMC: Mmcs_3860
MKM: Mkms_3934
MJL: Mjls_3846
MMI: MMAR_4071
MMM: W7S_06745
MLI: MULP_04237(glgE)
MHAD: B586_08280
MSHG: MSG_03642(glgE)
MFJ: MFLOJ_50240(glgE)
MSTO: MSTO_54500(glgE)
MXE: MYXE_16520(glgE)
MNV: MNVI_03650(glgE)
MNM: MNVM_05270(glgE_1) MNVM_23330(glgE_2)
MCOO: MCOO_17130(glgE)
MBAI: MB901379_03535(glgE)
MSEO: MSEO_24420(glgE)
MVA: Mvan_4301
MGI: Mflv_2344
MPHL: MPHLCCUG_03894(glgE)
MVQ: MYVA_4116
MTHN: 4412656_03150(glgE)
MHAS: MHAS_02677(glgE)
MDU: MDUV_03680(glgE)
MCHT: MCHIJ_28250(glgE)
MDR: MDOR_27170(glgE)
MAUU: NCTC10437_04045(glgE)
MMAG: MMAD_40220(glgE)
MMOR: MMOR_22430(glgE)
MFX: MFAL_00460(glgE)
MAIC: MAIC_39160(glgE)
MIJ: MINS_36280(glgE)
MALV: MALV_51270(glgE)
MTY: MTOK_01050(glgE)
MPSC: MPSYJ_25200(glgE)
MARZ: MARA_57070(glgE)
MGAD: MGAD_55620(glgE)
MHEV: MHEL_06300(glgE)
MSAR: MSAR_30130(glgE)
MANY: MANY_22540(glgE)
MAUB: MAUB_46410(glgE)
MPOF: MPOR_43990(glgE)
MAB: MAB_1468c
MABB: MASS_1460
MCHE: BB28_07310
MSTE: MSTE_01444(glgE)
MSAL: DSM43276_01331(glgE)
MTER: 4434518_01252(glgE_1) 4434518_03740(glgE_2)
MMIN: MMIN_29270(glgE)
MHIB: MHIB_08200(glgE)
ASD: AS9A_1342
MKR: MKOR_08480(glgE)
CGL: NCgl1178(Cgl1225)
CGB: cg1382(glgE)
CGU: WA5_1178(GlgE)
CGT: cgR_1303
CGM: cgp_1382(glgE)
CGJ: AR0_06625
CEF: CE1324
CDI: DIP1066
CDP: CD241_0975(glgE)
CDH: CDB402_0942(glgE)
CDT: CDHC01_0975(glgE)
CDE: CDHC02_0974(glgE)
CDR: CDHC03_0970(glgE)
CDA: CDHC04_0981(glgE)
CDZ: CD31A_1074(glgE)
CDB: CDBH8_1043(glgE)
CDS: CDC7B_0984(glgE)
CDD: CDCE8392_0971(glgE)
CDW: CDPW8_1040(glgE)
CDV: CDVA01_0937(glgE)
CDIP: ERS451417_00975(glgE)
CJK: jk1329(glgE)
CAR: cauri_1084(glgE)
CPL: Cp3995_0871(glgE)
CPP: CpP54B96_0869(glgE)
CPZ: CpPAT10_0855(glgE)
COR: Cp267_0893(glgE)
COD: Cp106_0841(glgE)
COS: Cp4202_0848(glgE)
CPSE: CPTA_01414
CPSU: CPTB_00118
CPSF: CPTC_01404
CRD: CRES_1407(glgE)
CUL: CULC22_00919(glgE)
CUC: CULC809_00904(glgE)
CUE: CULC0102_1017(glgE)
CUN: Cul210932_0947(glgE)
CUS: CulFRC11_0913(glgE)
CUQ: Cul210931_0907(glgE)
CUZ: Cul05146_0972(glgE)
CUJ: CUL131002_0925c(glgE)
COA: DR71_1888
CSX: CSING_05940(glgE)
CMQ: B840_05135(glgE)
CKU: UL82_03920(glgE)
CCJ: UL81_05040(glgE)
CMV: CMUST_06470(glgE)
CEI: CEPID_05170(glgE)
CTED: CTEST_05420(glgE)
CUT: CUTER_04515(glgE)
CDX: CDES_05955(glgE)
CSP: WM42_0268
CPHO: CPHO_07450
CGV: CGLAU_05370(glgE)
CAQU: CAQU_05295
CAMG: CAMM_08080
CMIN: NCTC10288_01452(glgE)
CPEG: CPELA_06515(glgE)
CEE: CENDO_04850(glgE)
CGK: CGERO_04685(glgE)
CCHO: CCHOA_04705(glgE)
CPSO: CPPEL_06735(glgE)
CSUR: N24_1347(glgE)
CCYS: SAMEA4530656_1341(glgE)
NFA: NFA_10790
NFR: ERS450000_03032(glgE)
NNO: NONO_c12760(glgE)
NSR: NS506_07170(glgE)
NAD: NCTC11293_01968(glgE)
NWL: NWFMUON74_59400(glgE)
RER: RER_38890(glgE)
REY: O5Y_18020
ROP: ROP_11570(glgE)
REQ: REQ_17750(glgE)
RHB: NY08_281
RFA: A3L23_03573(glgE)
RHS: A3Q41_04653(glgE)
RHU: A3Q40_00839(glgE)
RRT: 4535765_01720(glgE)
RCR: NCTC10994_01145(glgE)
GBR: Gbro_1956
GOR: KTR9_1890
GRU: GCWB2_09540(glgE)
GOM: D7316_00467(glgE_1)
TPR: Tpau_1279
SRT: Srot_1826
SCO: SCO5443(pep1A) SCO7335(pep1B)
SALB: XNR_1394
SMA: SAVERM_2802(amyA3) SAVERM_7395(amyA5)
SGR: SGR_2098
SGB: WQO_25005
SCB: SCAB_27981(pep1A) SCAB_83391(pep1B)
SMAL: SMALA_5398
SCT: SCAT_4255(pep1A)
SFA: Sfla_1893
SBH: SBI_03685(amyA1)
SVE: SVEN_5097
SDV: BN159_2960(pep1A) BN159_8322(pep1B)
SALS: SLNWT_1835
STRP: F750_4937
SFI: SFUL_5238
SALU: DC74_5569
SALL: SAZ_29425
SLV: SLIV_02620(glgE2) SLIV_11290(glgE1)
SGU: SGLAU_02530(glgE2) SGLAU_23370(glgE1)
STRE: GZL_03308
SLD: T261_2630
STRM: M444_23860
SAMB: SAM23877_0873(glgE) SAM23877_5185(glgE)
SPRI: SPRI_2442
SRW: TUE45_00877(glgE2) TUE45_05920(glgE1)
SLE: sle_22140(sle_22140) sle_65350(sle_65350)
SRN: A4G23_04019(glgE1)
SNR: SNOUR_14445(glgE1)
SLAU: SLA_5334
SALF: SMD44_06026(glgE)
SALJ: SMD11_2124(glgE)
SLX: SLAV_12640(glgE1)
SFK: KY5_5579c
SGE: DWG14_02702(glgE1) DWG14_07959(glgE2)
KSK: KSE_50690
LXL: KDY119_02470(glgE)
LXX: Lxx12580
CMI: CMM_1398
CMS: CMS0786
CMC: CMN_01370
MTS: MTES_3287
MOO: BWL13_01506(glgE1)
MLV: CVS47_01622(glgE1)
MOY: CVS54_01988(glgE1)
AMIN: AUMI_17880
AUW: AURUGA1_00584(glgE2)
AGX: AGREI_1139(glgE)
ART: Arth_0737
ARM: ART_3328
ARX: ARZXY2_3120(glgE)
AAGI: NCTC2676_1_00456(glgE1)
AAU: AAur_0908
ACH: Achl_0861
KRH: KRH_18650(glgE)
KVR: CIB50_0001225(glgE1)
BCV: Bcav_1337
JDE: Jden_1727
LMOI: VV02_19255
XCE: Xcel_2417
IDO: I598_3478(glgE2)
CFL: Cfla_1097
CFI: Celf_2761
SERJ: SGUI_1223
DCO: SAMEA4475696_0984(glgE1)
PAC: PPA1114
PAW: PAZ_c11630(glgE)
PACC: PAC1_05835
PACH: PAGK_1039
CACN: RN83_05940
CGRN: 4412665_01375(glgE2)
PFR: PFREUD_10660(glgE)
PFRE: RM25_1111
ACIJ: JS278_01563(glgE1)
MPH: MLP_29700(glgE)
TLA: TLA_TLA_00251(glgE1)
NCA: Noca_1809
NDK: I601_3877(glgE1)
PSIM: KR76_17900
MGG: MPLG2_1117(glgE)
KFL: Kfla_4941
TFU: Tfu_0585
NDA: Ndas_0249
NAL: B005_3113
STRR: EKD16_05675(glgE1)
TCU: Tcur_3583
SRO: Sros_8140
TBI: Tbis_2858
FAL: FRAAL5899
ACE: Acel_0679
NML: Namu_3176
GOB: Gobs_4100
MMAR: MODMU_4513(glgE)
KRA: Krad_1297
AMD: AMED_2596
AMN: RAM_13190
AMM: AMES_2568
AMZ: B737_2569
PDX: Psed_1730
PSEA: WY02_10615
PSEE: FRP1_03595
PSEH: XF36_19200
PAUT: Pdca_54250(glgE)
AMI: Amir_6072
SESP: BN6_72770(glgE)
KAL: KALB_7503
AHG: AHOG_06980(glgE)
MIL: ML5_2214
MSAG: GCM10017556_43760(glgE)
ASE: ACPL_5329(glgE)
ACTN: L083_5205(glgE)
ACTS: ACWT_5199
ATL: Athai_21200(glgE)
PRY: Prubr_33520(glgE)
AHE: Arch_0386
TPYO: X956_07815
TBW: NCTC13354_01509(glgE2)
AHW: NCTC11636_02541(glgE1)
AIR: NCTC12972_01298(glgE1)
ASLA: NCTC11923_01355(glgE1)
AVC: NCTC10951_01332(glgE1)
BLO: BL0388
BLJ: BLD_1190(dexA)
BLN: Blon_0282
BLON: BLIJ_0286
BLF: BLIF_0229
BLL: BLJ_0264
BLB: BBMN68_1127(dexA)
BLM: BLLJ_0247
BLG: BIL_17040
BAD: BAD_1435
BADL: BADO_1572
BLA: BLA_0654
BBB: BIF_01519
BBC: BLC1_1411
BLV: BalV_1412
BLW: W7Y_1454
BLS: W91_1485
BANI: Bl12_1368
BANL: BLAC_07325
BANM: EN10_07370
BDE: BDP_1968
BDN: BBDE_1855
BBP: BBPR_1658
BBI: BBIF_1599
BBF: BBB_1655
BBRU: Bbr_0296
BBRE: B12L_0253
BBRV: B689b_0282
BBRJ: B7017_0276
BBRC: B7019_0287
BBRN: B2258_0282
BBRS: BS27_0308
BBRD: BBBR_0257
BTP: D805_1569
BKS: BBKW_1684
BCAT: BBCT_1502
BPSP: AH67_07835
BANG: BBAG_0103
BPSC: BBPC_1592
BSCA: BBSC_0306
SIJ: SCIP_0146
PDO: PSDT_1415
RXY: Rxyl_0314
CYA: CYA_0263
RCA: Rcas_0393
CAU: Caur_1159
CAG: Cagg_2089
HAU: Haur_3868
TRO: trd_1930
STI: Sthe_1093
TTR: Tter_0331
TRA: Trad_1421
PNL: PNK_0134
WCH: wcw_1879
OTE: Oter_1105
XII: AMD24_00635(glgE1)
MIN: Minf_1992(amyA)
MKC: kam1_325
MEAP: MTHMO_1693(glgE)
PLS: VT03_15230(glgE2)
IPA: Isop_1163
SACI: Sinac_5857
AGV: OJF2_31890(glgE1)
PBU: L21SP3_00798(glgE2)
PBP: STSP1_00166(glgE)
ALUS: STSP2_01617(glgE1)
VBL: L21SP4_00491(glgE2)
ACA: ACP_0843
ABAS: ACPOL_5693
FSC: FSU_2442
GBA: J421_3816
PGI: PG_0897
PGN: PGN_1044
SRU: SRU_0848
SRM: SRM_01031
MGOT: MgSA37_01546(glgE1)
DFE: Dfer_0153
SLI: Slin_4658
FAE: FAES_1905
GFL: GRFL_1069
FSN: GS03_01565(glgE1)
MLT: VC82_334
WIN: WPG_2893
KOS: KORDIASMS9_04308(glgE2)
KAN: IMCC3317_13900(glgE2)
CTE: CT2089
CPC: Cpar_1961
CCH: Cag_1984
CLI: Clim_2379
PVI: Cvib_1673
PLT: Plut_2030
PPH: Ppha_2783
PAA: Paes_0210
PROC: Ptc2401_00162(glgE2)
FNO: Fnod_1144
MARN: LN42_04305
NMV: NITMOv2_3870(glgE)
NJA: NSJP_2229(glgE)
LFC: LFE_1036
PTO: PTO0068
CDIV: CPM_1881
 » show all
Reference
1  [PMID:20118231]
  Authors
Elbein AD, Pastuszak I, Tackett AJ, Wilson T, Pan YT
  Title
Last step in the conversion of trehalose to glycogen: a mycobacterial enzyme that transfers maltose from maltose 1-phosphate to glycogen.
  Journal
J Biol Chem 285:9803-12 (2010)
DOI:10.1074/jbc.M109.033944
  Sequence
Reference
2  [PMID:21914799]
  Authors
Syson K, Stevenson CE, Rejzek M, Fairhurst SA, Nair A, Bruton CJ, Field RA, Chater KF, Lawson DM, Bornemann S
  Title
Structure of Streptomyces maltosyltransferase GlgE, a homologue of a genetically validated anti-tuberculosis target.
  Journal
J Biol Chem 286:38298-310 (2011)
DOI:10.1074/jbc.M111.279315
  Sequence
[sco:SCO5443 SCO7335] [msm:MSMEG_4916] [mtu:Rv1327c]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.99.16
IUBMB Enzyme Nomenclature: 2.4.99.16
ExPASy - ENZYME nomenclature database: 2.4.99.16
BRENDA, the Enzyme Database: 2.4.99.16

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