Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
geranyl-diphosphate:2-O,3-dimethylflaviolin geranyltransferase (7-O-geranyl-2-O,3-dimethylflaviolin-forming)
geranyl diphosphate + 2-O,3-dimethylflaviolin = diphosphate + 7-O-geranyl-2-O,3-dimethylflaviolin [RN:
geranyl diphosphate [CPD:
The enzyme is involved in furaquinocin biosynthesis in the bacterium Streptomyces sp. KO-3988. It catalyses the transfer of a geranyl group to 2-O,3-dimethylflaviolin to yield 7-O-geranyl-2-O,3-dimethylflaviolin and 6-linalyl-2-O,3-dimethylflaviolin (cf. EC
, 6-linalyl-2-O,3-dimethylflaviolin synthase) in a 1:10 ratio.
EC 188.8.131.52 created 2014
K21341 6-linalyl-2-O,3-dimethylflaviolin/7-geranyloxy-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase
SQZ: FQU76_00200 FQU76_33540
PSUU: Psuf_091250 Psuf_091420 Taxonomy
Kumano T, Tomita T, Nishiyama M, Kuzuyama T
Functional characterization of the promiscuous prenyltransferase responsible for furaquinocin biosynthesis: identification of a physiological polyketide substrate and its prenylated reaction products.
ExPASy - ENZYME nomenclature database: 184.108.40.206