KEGG   ENZYME: 2.5.1.131
Entry
EC 2.5.1.131                Enzyme                                 

Name
(4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase;
MfnF
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
[5-(aminomethyl)furan-3-yl]methyl-diphosphate:gamma-L-glutamyltyramine [5-(aminomethyl)furan-3-yl]methyltransferase
Reaction(IUBMB)
[5-(aminomethyl)furan-3-yl]methyl diphosphate + gamma-L-glutamyltyramine = (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate [RN:R11040]
Reaction(KEGG)
R11040
Substrate
[5-(aminomethyl)furan-3-yl]methyl diphosphate [CPD:C21069];
gamma-L-glutamyltyramine [CPD:C20926]
Product
(4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine [CPD:C21070];
diphosphate [CPD:C00013]
Comment
The enzyme, isolated from the archaeon Methanocaldococcus jannaschii, participates in the biosynthesis of the methanofuran cofactor.
History
EC 2.5.1.131 created 2015
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
Orthology
K07072  (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase
Genes
MCA: MCA2869
METU: GNH96_03500
MMT: Metme_2271
MDN: JT25_019365
MDH: AYM39_08570
MKO: MKLM6_1784
METL: U737_14790
MAH: MEALZ_2434
MBUR: EQU24_09085
MPSY: CEK71_02035
MMAI: sS8_3387
MEJ: Q7A_51
MEC: Q7C_1778
NOC: Noc_0256
NHL: Nhal_3882
NWA: Nwat_0354
NTT: TAO_1760
MPT: Mpe_A2620
LCH: Lcho_3139
RGE: RGE_40350
MFA: Mfla_1649
MMB: Mmol_1334
MEH: M301_1543
MEP: MPQ_1555
XAU: Xaut_1791
SNO: Snov_0745
MDI: METDI2520
MEX: Mext_1836
MCH: Mchl_2171
MPO: Mpop_1787
MET: M446_5788
MNO: Mnod_6009
MOR: MOC_1181
META: Y590_08795
MSL: Msil_2392
HDN: Hden_1472
MSC: BN69_1050
MCG: GL4_1781
HDI: HDIA_2317
RBA: RB6209
PSL: Psta_3592
RUL: UC8_21020
PLM: Plim_0257
IPA: Isop_3533
SACI: Sinac_1216
MOX: DAMO_2658
MJA: MJ_0840
MMP: MMP0072
MMD: GYY_00365
MMAD: MMJJ_10220
MAE: Maeo_0623
MVO: Mvol_1437
MTH: MTH_834
METC: MTCT_0748
MWO: MWSIV6_1211(mfnF)
METE: tca_00801
MST: Msp_0386
MRU: mru_1695
MSI: Msm_0851
MEB: Abm4_0505
MMIL: sm9_1778
MEYE: TL18_07945
MOL: YLM1_1163
METH: MBMB1_0691
MFC: BRM9_1504
MCUB: MCBB_0702(mfnF)
MFV: Mfer_0209
MKA: MK0113
AFU: AF_0479
FPL: Ferp_0819
GAC: GACE_1625
GAH: GAH_00950
MBAR: MSBR2_1212
MBAK: MSBR3_1317
MAC: MA_1474
MMA: MM_2511
MMAC: MSMAC_2262
METM: MSMTP_0946
MTHR: MSTHT_0226
MTHE: MSTHC_0506
MHOR: MSHOH_2801
MBU: Mbur_1316
MMET: MCMEM_1763
MMH: Mmah_1620
MPY: Mpsy_2545
MTP: Mthe_0173
MCJ: MCON_2321
MHI: Mhar_2357
MHU: Mhun_0572
MLA: Mlab_0269
MEMA: MMAB1_1686
MPI: Mpet_1052
MBN: Mboo_0921
MPL: Mpal_0580
MPD: MCP_1325
MEZ: Mtc_1030
RCI: RCIX2219
BARB: AOA66_0933
 » show all
Reference
1  [PMID:26100040]
  Authors
Wang Y, Xu H, Jones MK, White RH
  Title
Identification of the Final Two Genes Functioning in Methanofuran Biosynthesis in Methanocaldococcus jannaschii.
  Journal
J Bacteriol 197:2850-8 (2015)
DOI:10.1128/JB.00401-15
  Sequence
[mja:MJ_0840]
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.131
IUBMB Enzyme Nomenclature: 2.5.1.131
ExPASy - ENZYME nomenclature database: 2.5.1.131
BRENDA, the Enzyme Database: 2.5.1.131

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