KEGG   ENZYME: 2.5.1.133
Entry
EC 2.5.1.133                Enzyme                                 

Name
bacteriochlorophyll a synthase;
bchG (gene name)
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
geranylgeranyl-diphosphate:bacteriochlorophyllide-a geranylgeranytransferase
Reaction(IUBMB)
geranylgeranyl diphosphate + bacteriochlorophyllide a = geranylgeranyl-bacteriochlorophyllide a + diphosphate [RN:R11514]
Reaction(KEGG)
R11514;
(other) R11517
Substrate
geranylgeranyl diphosphate [CPD:C00353];
bacteriochlorophyllide a [CPD:C18155]
Product
geranylgeranyl bacteriochlorophyllide a [CPD:C21217];
diphosphate [CPD:C00013]
Comment
The enzyme catalyses the addition of a geranylgeranyl hydrophobic chain to bacteriochlorophyllide a via an ester bond with the 17-propionate residue. The side chain is later modified to a phytyl chain, resulting in bacteriochlorophyll a.
History
EC 2.5.1.133 created 2016
Pathway
ec00860  Porphyrin and chlorophyll metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K04040  chlorophyll/bacteriochlorophyll a synthase
Genes
ATH: AT3G51820(G4)
ALY: 9312173
CRB: 17887345
CSAT: 104711728 104781015 104791427
EUS: EUTSA_v10010408mg
BRP: 103841124 103848641
BNA: 106349059 106367679 106388176 106402842 106402855 106437912
BOE: 106311688 106315573
RSZ: 108813242 108834478 108841552
THJ: 104805975
CPAP: 110820892
CIT: 102615732
TCC: 18597511
GRA: 105780406
GAB: 108457926
EGR: 104422084
VRA: 106758601
VAR: 108320403
VUN: 114186304
CCAJ: 109815417
APRC: 113861494
CAM: 101495080
LJA: Lj1g3v2372140.1(Lj1g3v2372140.1) Lj1g3v2372140.2(Lj1g3v2372140.2)
FVE: 101311975
RCN: 112192971
PPER: 18774974
PMUM: 103341648
PAVI: 110768439
PDUL: 117632895
ZJU: 107430876
MNT: 21399438
CSV: 101212175
CMO: 103502144
BHJ: 120074718
MCHA: 111013846
RCU: 8283148
HBR: 110672569
MESC: 110623146
QSU: 112005559
QLO: 115953950
TWL: 119984598
VVI: 100250669
VRI: 117920752
SLY: 101246752
SPEN: 107031547
SOT: 102580726
CANN: 107842693
NTA: 107781977(CHLG) 107794961(CHLG)
NSY: 104214712
NTO: 104101203
NAU: 109235321
SIND: 105174586
EGT: 105953109
HAN: 110865767
LSV: 111908627
CCAV: 112506489
DCR: 108215742
CSIN: 114318527
BVG: 104892512
SOE: 110794882
MING: 122088009
NCOL: 116255104
OSA: 4338498
DOSA: Os05t0349700-01(Os05g0349700)
OBR: 102706758
BDI: 100841031
ATS: 109739353
SBI: 8061338
ZMA: 100274372
SITA: 101764766
PHAI: 112893442
PDA: 103709366
EGU: 105044579
MUS: 104000955
DCT: 110111644
PEQ: 110023188
ATR: 18433480
PPP: 112290402
MNG: MNEG_2517
APRO: F751_6816
MIS: MICPUN_59614(CHLG)
MPP: MICPUCDRAFT_33362(CHLG)
SMIN: v1.2.019007.t1(symbB.v1.2.019007.t1)
FCY: FRACYDRAFT_223502(ChlG)
GTT: GUITHDRAFT_160205(CHLG)
ATEP: Atep_05710
TTP: E6P07_13130(chlG)
THIP: N838_12620(chlG)
CJAP: GWK36_13335(chlG)
THIM: KFB96_13290(chlG)
HHA: Hhal_1600
LIM: L103DPR2_01006(cyoE)
LIH: L63ED372_00662(cyoE)
HYR: BSY239_1280(bchG)
RGE: RGE_33410(bchG)
METR: BSY238_2471(bchG)
RPOD: E0E05_11920(chlG)
AGC: BSY240_3642(bchG)
ABAW: D5400_05065(chlG)
PDES: FE840_002455(chlG)
BRA: BRADO1634(bchG)
BBT: BBta_6422(bchG)
BRS: S23_19270(bchG)
AOL: S58_59030
BRO: BRAD285_5766(bchG)
BBET: F8237_24720(chlG)
RPA: RPA1530(bchG)
RPB: RPB_3992
RPC: RPC_1302
RPD: RPD_3747
RPE: RPE_1336
RPT: Rpal_1719
BOS: BSY19_4025(bchG)
MEA: Mex_1p5277(bchG)
MDI: METDI5877(bchG)
MEX: Mext_4820
MCH: Mchl_5287
MPO: Mpop_5365
MET: M446_3714
MOR: MOC_2257(chlG)
META: Y590_24630
MAQU: Maq22A_c01660(ubiA)
MMES: MMSR116_22230(chlG)
MSL: Msil_2061
BBAR: RHAL1_00140(bchG)
RVA: Rvan_1002
BVR: BVIR_566
BLAG: BLTE_02020
MROS: EHO51_17155(chlG)
CMET: K6K41_01520(chlG)
JAN: Jann_0165(bchG)
RDE: RD1_0144(bchG)
RLI: RLO149_p940670(bchG)
RPON: G3256_18965(chlG)
DSH: Dshi_3530(bchG)
ROM: EI983_05570(chlG)
MALU: KU6B_16720
RSP: RSP_0279(bchG)
RCP: RCAP_rcc00671(bchG)
PTP: RCA23_c29750(bchG)
RSU: NHU_00207(bchG)
RHC: RGUI_1990
LVS: LOKVESSMR4R_03328(ubiA)
TAW: EI545_18865(chlG)
POZ: I0K15_16875(chlG)
FAQ: G5B39_09975(chlG)
NGF: FRF71_09205(chlG)
NOG: GKE62_08495(chlG)
SPHI: TS85_23025
SSAN: NX02_18315
BLAS: BSY18_2713(bchG)
PALG: HFP57_06890(chlG)
PARJ: J4G78_07480(chlG)
SAND: H3309_05830(chlG)
POQ: KZX46_18585(chlG)
ALH: G6N82_11490(chlG)
POT: E2E27_07280(chlG)
AMV: ACMV_18920(bchG)
SKT: IGS68_17210(chlG)
RRU: Rru_A0627
RRF: F11_03215
RCE: RC1_2078(bchG)
RPM: RSPPHO_00053(bchG)
ELIO: KO353_02775(chlG)
HMO: HM1_0692(bchG)
HCV: FTV88_2637(bchG)
SYN: slr0056(chlG)
SYZ: MYO_123410(chlG)
SYY: SYNGTS_2317(chlG)
SYT: SYNGTI_2316(chlG)
SYS: SYNPCCN_2315(chlG)
SYQ: SYNPCCP_2315(chlG)
SYJ: D082_07670(chlG)
SYO: C7I86_12110(chlG)
SYC: syc2009_d(chlG)
SYG: sync_0696(chlG)
SYR: SynRCC307_0577(chlG)
SYX: SynWH7803_1776(chlG)
SYP: SYNPCC7002_A0548(chlG)
CYA: CYA_2138(chlG)
CYB: CYB_0533(chlG)
SYNR: KR49_13170
SYND: KR52_12905
SYH: Syncc8109_1904(chlG)
SYNW: SynWH8103_01908(chlG)
SYNC: CB0101_13790(chlG)
SYW: SYNW1677(chlG)
CYI: CBM981_1481(chlG)
PMA: Pro_0424(chlG)
PMM: PMM0428(chlG)
PMT: PMT_0272
PMB: A9601_04831(chlG)
PMC: P9515_04901(chlG)
PMF: P9303_20661(chlG)
PMG: P9301_04521(chlG)
PMH: P9215_05071(chlG)
PMJ: P9211_04241(chlG)
PME: NATL1_04811(chlG)
PRC: EW14_0470
PRM: EW15_0511
AMR: AM1_1019(chlG)
TVN: NIES2134_114550(chlG)
TEL: tll1539(chlG)
THN: NK55_04330(chlG)
THEC: FFX45_09895(chlG)
HHG: XM38_003210(chlG)
PSER: ABRG53_2590(chlG)
THEU: HPC62_19980(chlG)
MAR: MAE_22020(chlG)
MPK: VL20_3821
MVZ: myaer102_54720(chlG)
CYL: AA637_08970(chlG)
ENN: FRE64_01475(chlG)
CYT: cce_4122(chlG)
TER: Tery_0876
ARP: NIES39_C02140(chlG)
PAGH: NIES204_39460(chlG)
OXY: HCG48_00270(chlG)
LFS: HFV01_12050(chlG)
GVI: gvip248(chlG)
GLJ: GKIL_1505(chlG)
ANA: all4480(chlG)
NOE: CLI64_12480(chlG)
NSH: GXM_02835
NED: HUN01_24980(chlG)
AVA: Ava_3341
NAZ: Aazo_0020
ANB: ANA_C11932(chlG)
ANN: EH233_06540(chlG)
CALH: IJ00_11070
NSP: BMF81_03170(chlG)
DFS: HGD76_13480(chlG)
CCUR: IAR63_11390(chlG)
AFLO: HEQ12_11520(chlG)
TOQ: HCG51_21055(chlG)
CTHE: Chro_5252
STAN: STA3757_15840(chlG)
RCA: Rcas_3752
CHLO: J8C02_08665(chlG) J8C02_11935(chlG)
CTE: CT1270(chlG) CT1610(bchG)
CABY: Cabys_2935
 » show all
Reference
1  [PMID:9092496]
  Authors
Oster U, Bauer CE, Rudiger W.
  Title
Characterization of chlorophyll a and bacteriochlorophyll a synthases by heterologous expression in Escherichia coli.
  Journal
J Biol Chem 272:9671-6 (1997)
DOI:10.1074/jbc.272.15.9671
Reference
2  [PMID:10809697]
  Authors
Addlesee HA, Fiedor L, Hunter CN.
  Title
Physical mapping of bchG, orf427, and orf177 in the photosynthesis gene cluster of Rhodobacter sphaeroides: functional assignment of the bacteriochlorophyll synthetase gene.
  Journal
J Bacteriol 182:3175-82 (2000)
DOI:10.1128/JB.182.11.3175-3182.2000
  Sequence
[rsp:RSP_0279]
Reference
3  [PMID:12560989]
  Authors
Garcia-Gil LJ, Gich FB, Fuentes-Garcia X
  Title
A comparative study of bchG from green photosynthetic bacteria.
  Journal
Arch Microbiol 179:108-15 (2003)
DOI:10.1007/s00203-002-0506-3
Reference
4  [PMID:26258685]
  Authors
Saga Y, Hirota K, Harada J, Tamiaki H
  Title
In Vitro Enzymatic Activities of Bacteriochlorophyll a Synthase Derived from the Green Sulfur Photosynthetic Bacterium Chlorobaculum tepidum.
  Journal
Biochemistry 54:4998-5005 (2015)
DOI:10.1021/acs.biochem.5b00311
  Sequence
[cte:CT1610]
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.133
IUBMB Enzyme Nomenclature: 2.5.1.133
ExPASy - ENZYME nomenclature database: 2.5.1.133
BRENDA, the Enzyme Database: 2.5.1.133

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