KEGG   ENZYME: 2.5.1.147
Entry
EC 2.5.1.147                Enzyme                                 
Name
5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase;
cofH (gene name);
cbiF (gene name) (ambiguous)
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
5-amino-6-(D-ribitylamino)uracil:L-tyrosine, 4-hydroxyphenyl transferase
Reaction(IUBMB)
5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine = 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + L-methionine + 5'-deoxyadenosine [RN:R12161]
Reaction(KEGG)
R12161
Substrate
5-amino-6-(D-ribitylamino)uracil [CPD:C04732];
L-tyrosine [CPD:C00082];
S-adenosyl-L-methionine [CPD:C00019]
Product
5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil [CPD:C21971];
2-iminoacetate [CPD:C15809];
L-methionine [CPD:C00073];
5'-deoxyadenosine [CPD:C05198]
Comment
The enzyme is involved in the production of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), the precursor of the redox cofactor coenzyme F420, which is found in methanogens and in various actinobacteria. FO is also produced by some cyanobacteria and eukaryotes. The enzyme, which forms a complex with EC 4.3.1.32, 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, is a radical SAM enzyme that uses the 5'-deoxyadenosyl radical to initiate the reaction.
History
EC 2.5.1.147 created 2010 as EC 2.5.1.77, part transferred 2018 to EC 2.5.1.147
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K11779  FO synthase
K11781  5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase
Genes
VAQFIV01_04135(bioB1) FIV01_04140(mqnE)
PPHABVH74_17775(fbiC)
CPSCPS_4048 CPS_4049
ALTambt_18390(cofG) ambt_18395
AALEP13_00575 EP13_00580
AAUSEP12_00555
ASPAOR13_3368 AOR13_3369
ASQAVL57_01940 AVL57_01945
AAWAVL56_00750 AVL56_00755
ALEAV939_00755 AV939_00760
ALZAV940_00755 AV940_00760
ALTEALT761_00154 ALT761_00155
SNANI6N98_04750(cofH)
ZALAZF00_12035(fbiC)
OSGBST96_15205
MAGAMag101_11125(fbiC)
HJABST95_09655
HALCEY643_13155(cofH)
KIMG3T16_02855(cofH)
MPCMar181_0278 Mar181_0279
MPRIMP3633_0352(cofG) MP3633_0353(cofH)
MFOIJSY38_07525(cofH) JSY38_07530(cofG)
MRHIKDW99_18330(cofH) KDW99_18335(cofG)
MPONMACH16_28810 MACH16_28820
MARSA8C75_03565 A8C75_03570
MRZKDW95_12775(cofH) KDW95_12780(cofG)
SDFACG33_00245(fbiC)
BPYBphyt_4251 Bphyt_4252
PSPWBJG93_33610(cofH)
BRHRBRH_02551
APESFOC84_15060(cofH)
PUDG9Q38_02370(cofH)
DOEDENOEST_1265(fbiC) DENOEST_3709(fbiC)
EBAp2A350
AZIAzCIB_1481
AZDCDA09_09830(fbiC)
TAKTharo_0194
THAGCKCBHOJB_02347(fbiC_1) CKCBHOJB_02385(fbiC_2)
MESPC1M53_21080(cofH) C1M53_21085(cofG)
ANJAMD1_0564(fbiC)
SMEGC770_GR4pC0061
ARUIG6M88_23510(cofH)
KAIK32_16310(fbiC)
BRKCWS35_20200(fbiC)
BQBJ4P68_0009780(cofH)
BRAZLRP30_33420(cofH)
RPBRPB_4423
OCAOCAR_5007
OCGOCA5_c29510(fbiC)
STARG3545_06785(cofH)
LNEFZC33_07430(cofH)
SNOSnov_4230
APRAG3A50_01690(cofH)
MOGMMB17_16620(cofH)
HMCHYPMC_3547(fbiC)
METGHT051_05445(cofH) HT051_12625(cofH)
RBMTEF_20090(fbiC)
PSFPSE_2792(fbiC) PSE_2793(fbiC)
PZUPHZ_c2536
LMDMETH_04450 METH_04455
LAQUR2C4_00575(cofH) R2C4_00580(cofG)
LCAEK3721_20520(cofH) K3721_20525(cofG)
PDEPden_1114 Pden_1115
PALPJHW40_21090(cofH) JHW40_21095(cofG)
RMBK529_001420 K529_001425
THASC6Y53_09640(cofH) C6Y53_09645(cofG)
LVRT8T21_15005(cofH) T8T21_15010(cofG)
BOSGGKR98_14125(cofH)
NPNJI59_17370(fbiC)
NREBES08_02715(fbiC) BES08_26705(fbiC)
NOVTQ38_007750(fbiC)
SPHOC3E99_13050(fbiC)
SPHUSPPYR_1437(fbiC)
SWISwit_0717
SPHDHY78_17635(fbiC) HY78_23110(fbiC)
RDICMV14_13670(fbiC)
SPHMG432_01225(fbiC)
SPKCKC8_02690 KC8_06240
SBINSBA_ch2_0980(fbiC)
SNAPPQ455_18695(cofH)
SCHSphch_0610 Sphch_2129
SYBTZ53_17125(fbiC) TZ53_18465(fbiC)
SBDATN00_17480(fbiC)
SPMIK663_16861(fbiC)
SPHBEP837_03073(fbiC)
SPHTK426_12255(fbiC) K426_23844(fbiC)
SHYDCJD35_15490(fbiC)
SYAA6768_05840(fbiC)
SCLOSCLO_1006370
SUFLFIL70_06835(cofH)
SBARH5V43_00775(cofH) H5V43_05145(cofH)
SPPHKFK14_07095(cofH)
BLASBSY18_2471(cofG)
SPHJBSL82_04895(fbiC) BSL82_08920(fbiC)
CMANA9D14_14800(fbiC)
NTDEGO55_02465(cofH)
CAENK5X80_05825(cofH)
KHAIFJ82_10850(cofH)
MZLGKS04_01915(cofH)
PAUUE8A73_035590(cofH) E8A73_035595(cofG)
HOHHoch_0059
BBEVBBEV_1716(cofG) BBEV_1717(fbiC)
BSEBsel_1864 Bsel_1865
NCDACONDI_01245(fbiC_1)
ERZER308_14055
EUZDVS28_a4427
MTURv1173(fbiC)
MTVRVBD_1173
MTCMT1210
MRAMRA_1184(fbiC)
MTFTBFG_11198
MTBTBMG_02808
MTKTBSG_02822
MTZTBXG_002788
MTGMRGA327_07395(fbiC)
MTECCDC5079_1085
MTURCFBS_1252(fbiC)
MTLCCDC5180_1078
MTOMTCTRI2_1205(fbiC)
MTDUDA_1173(fbiC)
MTNERDMAN_1316(fbiC)
MTJJ112_06345(fbiC)
MTUBMT7199_1203
MTUEJ114_06345(fbiC)
MTXM943_06155(fbiC)
MTULTBHG_01157
MTUTHKBT1_1250(fbiC)
MTUUHKBT2_1256(fbiC)
MTQHKBS1_1254(fbiC)
MBOBQ2027_MB1206(fbiC)
MBBBCG_1236(fbiC)
MBTJTY_1209(fbiC)
MBMBCGMEX_1208(fbiC)
MBKK60_012660
MBXBCGT_1005
MAFMAF_11920(fbiC)
MMICRN08_1318
MCEMCAN_11841(fbiC)
MCQBN44_11312(fbiC)
MCVBN43_30241(fbiC)
MCXBN42_21039(fbiC)
MCZBN45_30234(fbiC)
MORYMO_001264
MLEML1492
MLBMLBr01492
MPAMAP_2611c
MAOMAP4_1207
MAVIRC58_05980(fbiC)
MAVURE97_05975(fbiC)
MAVMAV_1312
MITOCO_12230
MIAOCU_12190
MIDMIP_01953
MYOOEM_12380
MCHIAN480_07165(fbiC)
MIROCQ_12250 OCQ_17070
MMALCKJ54_05940(fbiC)
MLPMLM_1243
MMANMMAN_27770(fbiC)
MSAMycsm_04923
MULMUL_1020(fbiC)
MMIMMAR_4279(fbiC)
MMAEMMARE11_40940(fbiC)
MLIMULP_04464(fbiC)
MPSEMPSD_44060(fbiC)
MSHOMSHO_14720(fbiC)
MMCMmcs_4032
MKMMkms_4107
MJLMjls_4262
MMMW7S_05970(fbiC)
MKNMKAN_07265(fbiC)
MYVG155_22255(fbiC)
MYEAB431_23285(fbiC)
MHADB586_07415(fbiC)
MDXBTO20_08855(fbiC)
MSHGMSG_03833(fbiC)
MFJMFLOJ_48330(fbiC)
MSTOMSTO_52240(fbiC)
MSIMMSIM_38270(fbiC)
MSAKMSAS_21160(fbiC)
MKUI2456_20125
MLWMJO58_21010
MXEMYXE_14930(fbiC)
MNVMNVI_05210(fbiC)
MPAGC0J29_23420(fbiC)
MNMMNVM_06740(fbiC)
MGORH0P51_21610
MCOOMCOO_19510(fbiC)
MBAIMB901379_03732
MSEOMSEO_26110(fbiC)
MHEKJMUB5695_01421(fbiC)
MGAUMGALJ_28990(fbiC)
MLJMLAC_07790(fbiC)
MBRDMBRA_28580(fbiC)
MSHJMSHI_03820(fbiC)
MMAMK3U93_18445
MSPGF6B93_17105
MOTLTS72_03905
MLMMLPF_2144(fbiC)
MPAAMKK62_06105
MMEHM5I08_20060
MKYIWGMT90018_48980(fbiC)
MADIA7U43_09785(fbiC)
MWUPT015_11255
MSMMSMEG_5126
MSGMSMEI_4998(fbiC)
MSBLJ00_25350(fbiC)
MSNLI99_25355(fbiC)
MSHLI98_25360(fbiC)
MVAMvan_4533
MGIMflv_2167
MSPMspyr1_15990
MCBMycch_3937
MNED174_20945(fbiC)
MYNMyAD_20555(fbiC)
MFTXA26_45380
MPHLMPHLCCUG_04074(mqnE)
MVQMYVA_4308(fbiC)
MLLB1R94_06840(fbiC)
MRHMycrhN_3645
MTHN4412656_03414
MHASMHAS_02879(fbiC)
MDUMDUV_01960(fbiC)
MCHTMCHIJ_26390(fbiC)
MDRMDOR_28370(fbiC)
MAUUNCTC10437_04265
MMAGMMAD_41900(fbiC)
MMORMMOR_20550(fbiC)
MFXMFAL_38670(fbiC)
MAICMAIC_42080(fbiC)
MIJMINS_37690(fbiC)
MALVMALV_49400(fbiC)
MTYMTOK_03550 MTOK_55600(fbiC)
MPSCMPSYJ_23260(fbiC)
MARZMARA_55100(fbiC)
MGADMGAD_53420(fbiC)
MHEVMHEL_08660(fbiC)
MSARMSAR_27780(fbiC)
MANYMANY_25620(fbiC)
MAUBMAUB_44400(fbiC)
MPOFMPOR_45990(fbiC)
MPHUMPHO_24960(fbiC)
MMUCC1S78_005905
MMATMMAGJ_04430(fbiC)
MBOKMBOE_28340(fbiC)
MFGK6L26_09515
MSEIMSEDJ_54070(fbiC)
MFLVNCTC10271_01195
MCEEMCEL_45020(fbiC)
MBRML2Z93_000870
MMONEWR22_21865
MGOAFA91_14910(fbiC)
MHOLK3U96_06440
MSENK3U95_21350
MPAEK0O64_22840
MRFMJO55_20460
MDFK0O62_21950
MCROMI149_23265
MGROFZ046_26035
MKRMKOR_00500(fbiC)
MABMAB_1319
MMVMYCMA_0695(fbiC)
MABBMASS_1319(fbiC)
MABLMMASJCM_1346
MIZBAB75_07105(fbiC)
MSTEMSTE_01287
MSAOMYCSP_05810(fbiC)
MSALDSM43276_01185(mqnE)
MJDJDM601_1161(fbiC)
MTER4434518_01112(fbiC)
MMINMMIN_27930(fbiC)
MHIBMHIB_06830(fbiC)
MHERK3U94_06425
MVMMJO54_06595
ASDAS9A_3366(fbiC)
NFANFA_47520
NFRERS450000_05176
NCYNOCYR_4499(fbiC)
NBRO3I_035915(fbiC)
NNONONO_c64550(fbiC)
NSLBOX37_25530(fbiC)
NSRNS506_01897(fbiC)
NTPCRH09_33525(fbiC)
NOZDMB37_14595(fbiC)
NODFOH10_02850
NAHF5544_37870
NADNCTC11293_06076
NWLNWFMUON74_12070
NIEKV110_34935
NTCKHQ06_12095(cofG)
NHUH0264_11435
NYALTV02_21365
NGPLTT66_19030
NSPUIFM12276_07970
NYUD7D52_01405
RHARHA1_ro05944 RHA1_ro11041
RERRER_41830(fbiC)
REYO5Y_19555(fbiC)
REBXU06_19700(fbiC)
RQIC1M55_20650(fbiC)
ROPROP_60060(fbiC)
ROAPd630_LPD02578
RPYY013_22830(fbiC)
RBYCEJ39_09030(fbiC)
RHBNY08_5017
RAVAAT18_08315(fbiC)
RFAA3L23_03076(fbiC)
RHSA3Q41_00251(fbiC)
RHWBFN03_02640(fbiC)
RRZCS378_23345(fbiC)
RHUA3Q40_02330(fbiC)
RHQIM25_12240(fbiC)
RHODAOT96_01090(fbiC)
RRT4535765_01329
RCRNCTC10994_01473
RTMG4H71_03820
RKOJWS14_25800 JWS14_32470
RGOKYT97_28070
ROZCBI38_21010(fbiC)
RPSKJWS13_11460 JWS13_28415(cofH)
RGORNMQ04_05840
RANTRHODO2019_12410
RHOPD8W71_24065
RHOORA302_20300
RHOUKZJ41_08890
REQREQ_14170
WHROG579_06020
GBRGbro_3324 Gbro_3326
GPOGPOL_c31220(fbiC1) GPOL_c31240(fbiC2)
GORKTR9_3363 KTR9_3365
GOQACH46_05885(fbiC)
GTABCM27_17075 BCM27_17085
GOCCXX93_08415(fbiC)
GITC6V83_14745(fbiC)
GRUGCWB2_17295 GCWB2_17305(mqnE)
GOMD7316_05361(fbiC_1) D7316_05363(fbiC_2)
GAVC5O27_10895 C5O27_10905(cofG)
GODGKZ92_16225(cofG) GKZ92_16235
GAMGII34_16115(cofG) GII34_16125
GPDGII33_15575(cofG) GII33_15585
GJIH1R19_16160(cofG) H1R19_16170
GOILK459_17770(cofG)
GHNMVF96_16540(cofG) MVF96_16550
GAMIIHQ52_20080(cofG) IHQ52_20090
GMGNWF22_01595(cofG)
GSIP5P27_13840
SPINKV203_14900
TPRTpau_1148
TSMASU32_06460(fbiC)
TPULTPB0596_34700
TSDMTP03_12000
SRTSrot_0835
DTMBJL86_2044
DITC3V38_15800(fbiC)
DIZCT688_09915(fbiC)
DPCA6048_10140(fbiC)
DLUA6035_09660(fbiC)
DKNNHB83_09505
TOYFO059_07605
SCOSCO4429(fbiC)
SALBXNR_2222
SMASAVERM_3794(cofG)
SGRSGR_4235
SGBWQO_14275(fbiC)
SFISFUL_2886
SANLKZO11_14740
SGRFSGFS_053720
SCYER2B67_21015
SCBSCAB_52181(fbiC)
SSXSACTE_2687
SVLStrvi_1011
SHYSHJG_4710
SHOSHJGH_4472
SRCM271_20760(fbiC) M271_38995(fbiC)
SMALSMALA_4583 SMALA_6223
SSOII1A49_26975 I1A49_34955
SFASfla_3633
SBHSBI_06333(fbiC)
SVESVEN_3084
SDVBN159_5026(fbiC)
SALSSLNWT_4334
STRPF750_3084
SCIB446_16865(fbiC)
SLVSLIV_16290(fbiC)
SGUSGLAU_14900(fbiC)
SVTSVTN_16080(fbiC)
STREGZL_05186
SCWTU94_14370(fbiC)
SLDT261_4807
SLCSL103_02830(fbiC)
SXISXIM_33060
STRMM444_15375(fbiC)
STRCAA958_12800(fbiC)
SAMBSAM23877_3304(fbiC)
SPRISPRI_4317
SCZABE83_21500(fbiC)
SCXAS200_26105(fbiC)
SRWTUE45_04323(mqnE_1)
STRFASR50_19115(fbiC)
SLEsle_40200(sle_40200)
SRNA4G23_02305(mqnE_1)
SPAVSpa2297_14305(fbiC)
STRTA8713_13345(fbiC)
SCLFBB341_11230(fbiC)
SGSAVL59_44175(fbiC)
STSIA4E84_17315(fbiC)
SKYD0C37_12855
SALWCP975_15010
SGMGCM10017557_35530(fbiC)
SCADDN051_22345(fbiC)
SPHWNFX46_37170
SLSSLINC_3698
SNRSNOUR_23810(fbiC)
SALUDC74_3703
SALLSAZ_19675(fbiC)
SPLULK06_018940(fbiC)
STRDNI25_22395(fbiC)
SNWBBN63_19680(fbiC)
SAUOBV401_26765(fbiC) BV401_35045(fbiC)
SSIAA7J05_20325(fbiC)
SVUB1H20_13635(fbiC)
SPUNBFF78_24080(fbiC)
SGVB1H19_17935(fbiC)
SLAUSLA_3135
SALFSMD44_03660(fbiC)
SALJSMD11_3959(fbiC)
SLXSLAV_16495(mqnE2)
STROSTRMOE7_16995(fbiC)
SFKKY5_3501c
SNZDC008_14780(fbiC)
SGEDWG14_04813(fbiC)
SRJSRO_4209
SLKSLUN_16960(fbiC)
SDXC4B68_22925(fbiC)
SGDELQ87_22200
SQZFQU76_13045
SCYAEJ357_19745
SASTCD934_19070(fbiC)
SNQCP978_15160
STIRDDW44_12900(fbiC)
SKACP970_24850
SGZC0216_28065(fbiC)
SVNCP980_19530
SNKCP967_19890
SHAWCEB94_17765(fbiC)
SRKFGW37_13610
SFICEIZ62_19010
SGALCP966_15640
SSPODDQ41_12865(fbiC)
SVRCP971_13825
SPADDVK44_19985
SFYGFH48_04685 GFH48_23250
SAQUEJC51_21990
SGFHEP81_04381
SCAVCVT27_13110(fbiC)
SSEOD0Z67_12435
SBYH7H31_12565
SRIMCP984_22985
SSUBCP968_19360
SPHVF9278_20425
SCINCP977_14980
SFUGCNQ36_15020(fbiC)
SPACB1H29_21215(fbiC)
STSUB7R87_12590(fbiC)
SCHACP983_24350
SGXH4W23_17365
SCOECP976_19180
SBATG4Z16_19750
SSPBCP982_19215
SNFJYK04_03838(fbiC)
SPLACP981_16730
SBROGQF42_20285
STUIGCM10017668_29810(fbiC)
SATAC5746_17895(fbiC)
SCHFIPT68_15990
SHUNDWB77_04425(fbiC)
SHARHUT13_16975
SCYGS1361_17510(mqnE1)
SFEUIM697_04550
SLIAHA039_20010
SDWK7C20_15990
SCALI6J39_13895
SAUHSU9_014230
SFBCP974_12675
SMOBJ7W19_13420
SPRACP972_15785
SPEUCGZ69_15300(fbiC)
SROIIAG44_23535
SXNIAG42_20105
SGJIAG43_13245
SHKJ2N69_15415
SANUK7396_20810
SDDD9753_20105
SACTDMT42_17110(fbiC)
SMAOCAG99_16115(fbiC)
SGOBtest1122_09690
SINEKI385_19785
SLFJEQ17_20290
SDECL3078_19665
SAOVG3H79_21110
SDURM4V62_24300
SYANNRK68_14460
SRUGF0345_17100
SAKBK1J60_25135
STAALDH80_23135
SNIGHEK616_00550(fbiC)
SVIOHWN34_11700
SCAEIHE65_25655
STUBMMF93_14250
SSPNLXH13_23380
SCIRSTRCI_003624
SXTKPP03845_103369(fbiC)
SLONLGI35_20770
SDRZNEH16_18230
STUDSTRTU_004112
STEEF3L20_29425
SENGOJ254_11855
SGKPET44_14130
SANTQR300_18265 QR300_34400
SYUNMOV08_24245
SARGHKX69_19635
SJNRI060_24320
SCYNN8I84_18200
SOVQZH56_20860
SFIYF0344_20995
SHAUK9S39_25675
SKGKJK29_21620
SCOAQU709_24225
SROCRGF97_19325
SFPQUY26_22730
SCHGNRO40_12830
STTNBSL84_14230(fbiC)
SINNABB07_21615(fbiC)
STRZOYE22_12340
SCAYPYS65_20555
KBUQ4V64_22495
SARMDVA86_19975
SPRFK4G22_17625
SCTSCAT_2338(fbiC)
SCYSCATT_23240
KSKKSE_45370(fbiC)
KABB7C62_13575(fbiC)
KAUB6264_08870(fbiC)
KITCFP65_4503
KISHUT16_20905
STRIC7M71_018075 C7M71_029935
YIALO772_20335
STRHGXP74_04320
ABRYNYE86_04115
AGLAOIE69_23170
MTSMTES_1880
MCWA8L33_02330(fbiC)
MIHBJP65_10345(fbiC)
MLVCVS47_03051(fbiC)
MWAE4K62_17115(cofG)
MPRTET475_03910(cofG)
MSEDE3O41_12525(cofG)
MSFIT882_14560(cofG)
MCAWF6J84_13710(cofG)
MLZF6J85_16135(cofG)
MBINLXM64_14320(cofG)
MTECOAU46_00565(cofG)
MRGSM116_03190(cofG)
MINVT9R20_15320(cofG)
MOJD7D94_11955(cofG)
MLIYRYJ27_01240(cofG)
MICEEHF32_14365(cofG)
RTNA6122_2036
RRYC1O28_02855(cofG)
RIAC7V51_08340(cofG)
RFSC1I64_01800(cofG)
RTEGSU10_11030(cofG)
ROEQ0F99_01835(cofG)
FSBGCM10025867_09910(fbiC)
AMAUDSM26151_01330(fbiC)
CPHYB5808_13295
CHREIE160_09580
MHUMNNL39_01305
MDBOVN18_01215
HUMDVJ78_07475(cofG)
HUWFPZ11_07345
GRYD7I44_06910(cofG)
HEAHL652_10815
GLNF1C58_11635(cofG)
AGXAGREI_2251(fbiC)
SUBALQ955_13810(cofG)
AOGLH407_06225(cofG)
LMOIVV02_14120(fbiC)
BEIGCM100_11710(fbiC)
SKESked_13970
ARSADJ73_02705(fbiC)
TEDU5C87_00695(cofG)
NCANoca_0814 Noca_0863 Noca_3619
NDKI601_0314(mqnE)
NOYEXE57_07410
NOOFE634_06500
NSNEXE58_11165
NBEBack2_26860(fbiC)
NANOG5V58_03040
NAROCFH99_19185(fbiC) CFH99_24610(fbiC)
NAQUENKNEFLB_01161(fbiC)
NROK8W59_12810
NOQLN652_12940
NPCKUV85_09375
NMARHPC71_17040
PSIMKR76_06880
AEFGEV26_03330
ASEZH9L21_12180(cofG)
ADBNP095_12130(cofG)
AWNNQV15_14405
MUZH4N58_04665
NBTKLP28_08780
KFLKfla_6490
KQIF1D05_17210
KSLOG809_08315
KRIOX958_04495
TFUTfu_2519
THAONI17_015405
TALXFOF52_12875
NDANdas_3771
NALB005_0949(cofG)
NGVCDO52_24260(fbiC)
NEXNE857_28345
NAKEKGD83_06355
NCGKGD84_05625
STRREKD16_20105(mqnE)
SNAHOUQ99_05220
SAIUJ4H86_12310
TCUTcur_4075
ACTWF7P10_11805
AGRAAGRA3207_002960
AMAZLUW76_18155
ACIROG979_24040
SPIQOHA34_18505
ACTQOG417_07100
SROSros_1376
NOABKM31_38790(fbiC)
NOWGBF35_06580
NCXNocox_05935(mqnE)
NGNLCN96_06620
NFSOIE67_40380
TBITbis_0746
MHAIOHB01_17490
FRAFrancci3_0745
FALFRAAL1263
FREFranean1_5865
FSYFsymDg_1082
FRIFraEuI1c_6068
ACEAcel_0769
NMLNamu_4262
NAKEH165_03525
NAKAH7F38_14650
GOBGobs_1483
BSDBLASA_1295(fbiC)
BLAPMVA48_07520 MVA48_08880
MMARMODMU_1466(fbiC)
MOMKUM42_16635
KRAKrad_3629 Krad_3632
SENSACE_6594
SACGFDZ84_07940
AMDAMED_6904(fbiC)
AMNRAM_35420(fbiC)
AMMAMES_6798(fbiC)
AMZB737_6798(fbiC)
AOIAORI_1815(fbiC)
AJAAJAP_30405(fbiC)
AMQAMETH_5642(fbiC)
AMYCCU254_27985(fbiC)
AMYBBKN51_01275(fbiC)
AABA4R43_34635(fbiC)
AMYYYIM_43415(mqnE)
AORISD37_32150(fbiC)
AACDLWP59_32540
APRTMUY14_02010
AROONQK81_13895
ATHML1857_31135
ARHDVSH64_23995
AMOGQRX60_24495
ACYNORV05_03545
PDXPsed_5307
PSEAWY02_11900(fbiC)
PSEEFRP1_02325(fbiC)
PSEHXF36_01695(fbiC)
PSEQAD006_09945(fbiC)
PECQAD017_17775(fbiC)
PHHAFB00_15685(fbiC)
PAUTPdca_57260(fbiC)
PBROHOP40_12740
PPELH6H00_12765
APRECNX65_31760(fbiC)
AMIAmir_6472
SESPBN6_77580(fbiC)
SSYIEKG83_43130
SACXIOD16_32880
KALKALB_8047
KUTJJ691_85780(fbiC)
KPHYAOZ06_48880(fbiC)
LEDBBK82_18465(fbiC)
AHMTL08_13605
ACTIUA75_18405
ACADUA74_17915
AHGAHOG_15900(mqnE)
ACTAC1701_18075(fbiC)
ALOCRK57346
PMADBAY61_03415(fbiC)
SACEGIY23_19430
ACTUActkin_03687
CROSN8J89_04080
UMERM788_21350
STPStrop_0946
SAQSare_0888
MAUMicau_0954
MILML5_1202
MICBMicB006_1000
MTUACSH63_19720(fbiC)
MICHFJK98_05060
MTEMGCE86_30280
MCABHXZ27_05710
MSAGGCM10017556_35230(fbiC)
VMAVAB18032_09475(fbiC)
MCRAID554_08055
VERHUT12_05635
MENOJiend_19020(fbiC)
MCHLPVK74_26035
MFEUH1D33_11390
MPRNQ3V37_02275
MHAWRMN56_06860
ASEACPL_1050(fbiC)
AMSAMIS_34700 AMIS_8560
ACTNL083_1155(fbiC)
AFSAFR_05660(fbiC)
ACTSACWT_0932
AIHAiant_52230(fbiC)
ACTRAsp14428_35930(fbiC)
ACTLL3i22_009090(fbiC)
ASICQ0Z83_079550
AOUACTOB_000877
PLABC6361_20395(fbiC)
PLATC6W10_23365(fbiC)
PFLAPflav_062050 Pflav_062060
PSUUPsuf_023990 Psuf_024000
PRYPrubr_13790(fbiC)
CATICS0771_04600(fbiC)
DVCDvina_48720
DFUDfulv_43300
DROSDrose_33150
DAURDaura_46955
DMATDmats_43260
DACTKZZ52_55295
NHYJQS43_20520
CCAZCOUCH_33970
CAICaci_8766
AEYCDG81_19075(fbiC)
EKEEK0264_11715
JTLM6D93_14695
JCYM6B22_08540
ABAIIMCC26256_111175
RXYRxyl_0975
RRDRradSPS_0884
RUBGBA63_07155(cofH)
RMARGBA65_08975(cofH)
BSOLFSW04_11700(cofH)
BALADSM104299_01943(fbiC)
PBAJLRS13_14345(cofH)
CWOCwoe_4090 Cwoe_4147 Cwoe_4165
PARNNBH00_07350(cofH)
SBAEDSM104329_01345(fbiC_1) DSM104329_02932(fbiC_2)
TALUJDY09_03360(cofH)
AFOAfer_0900
AYMYM304_13120(fbiC)
ATQGH723_13920(cofH)
AQZKSP35_04415(cofH)
IAMHC251_10875
IMAPO878_10650
DHILH044_02515
SYNsll1659
SYZMYO_12520
SYYSYNGTS_0250(cofH)
SYTSYNGTI_0250(cofH)
SYSSYNPCCN_0250(cofH)
SYQSYNPCCP_0250(cofH)
SYJD082_03150
SYOC7I86_01305
SYCsyc0843_c
SYUM744_13360
SYFSynpcc7942_0686
SYNESyn6312_0669
SYNCCB0101_02280
DSLDacsa_2777
CYICBM981_0450(cofH)
WNAKA717_35230(cofH)
CMPCha6605_0213
CYNCyan7425_3281
CEPCri9333_0183
TVNNIES2134_115350
SLWBRW62_07230
TELtlr1597
THNNK55_04740(cofH)
THECFFX45_05945(cofH)
THEYJW907_10010(cofH)
TSZOOK60_08670(cofH)
LENLEP3755_03060
LETO77CONTIG1_00551(mqnE)
LBOLBWT_33850
LEPTJVX88_12175(cofH)
KOVK9N68_30215(cofH)
LSCKIK02_21135(cofH)
LSKJ5X98_12360(cofH)
HHGXM38_009170(cofH)
THEUHPC62_14945(cofH)
TOGHNI00_17830(cofH)
TSINOXH18_10610(cofH)
GLPGlo7428_1689
CHONNIES4102_20330
GDUP0S91_19785(cofH)
GENGM3709_1153
GEEGM3708_16
CANCyan10605_1120
CSNCyast_0246
CYLAA637_02275(cofH)
SYPSYNPCC7002_A1920
SYVAWQ23_09655
SYLAWQ21_08970
LEPLepto7376_2105
SYNNNIES970_22200
PIPFEK30_13935(cofH)
MARMAE_44400
MPKVL20_2553
MIQB5D77_03435
MVZmyaer102_18520
HAOPCC7418_2609
ENNFRE64_08190(cofH)
CYUUCYN_08790
CYTcce_4539
CWACwatDRAFT_4020
CYPPCC8801_3080
CYHCyan8802_3040
CYCPCC7424_1434
CYJCyan7822_2858
TERTery_2116
ARPNIES39_L02990(cofH)
PAGHNIES204_22650
PPSUNO713_00547(cofH)
PRUNPCC7821_02736(cofH)
OXYHCG48_14355(cofH)
MVAGD0A34_20040(cofH)
LFSHFV01_04975(cofH)
LIXH2674_20600(cofH)
OACOscil6304_4047
ONIOsc7112_3345
MPROBJP34_21195
PHORJWS08_17640(cofH)
PYHNEA10_15280(cofH)
MICMic7113_5310
GEIGEI7407_2659
GVIglr0776
GLJGKIL_2220(cofH)
GMLISF26_03635(cofH)
ANAalr4129
NPUNpun_R6205
NOSNos7107_3642
NOPNos7524_0859
NONNOS3756_00900
NFLCOO91_07430
NOECLI64_00875
NSHGXM_01176
NEDHUN01_31190(cofH)
NPZACX27_05495
NLKNIES25_22540
AVAAva_0775
NAZAazo_0194
ANBANA_C11401(cofH)
ACYAnacy_2798
AWAAA650_07120
ANNEH233_04440(cofH)
CSGCylst_3746
RSINB6N60_01462
HBQQI031_24085(cofH)
CALOCal7507_2039
CALTCal6303_4393
CALHIJ00_17760
CALNNIES2098_55660
CALSNIES3974_40850
RIVRiv7116_1180
MDPNIES3275_61510
FISFIS3754_21440
NSPBMF81_01996(cofH)
NSPHBDGGKGIB_02192(fbiC_1)
DOUBMF77_01492(fbiC_1)
DFSHGD76_10455(cofH)
DHTNG743_18275(cofH)
DCMNIES806_20470
DOTEZY12_07385(cofH)
DOZHEP80_11255(cofH)
CCURIAR63_12380(cofH)
CRKL3I90_11785(cofH)
AFLOHEQ12_13685(cofH)
STOQK2F26_10480(cofH)
SKVNIES73_31930
AEEIM676_09145(cofH)
RCSNIES932_30160
TOQHCG51_15175(cofH)
ALAXNIES50_14340
SCYTSAMD_34770
SCYSNIES4073_68460
BSENDP114_12470
BOXDP113_12405
NCNBZZ01_30745
CTHEChro_1933
PLPPle7327_4035
SCSSta7437_2830
STANSTA3757_07450
GLTGlitD10_1239(cofH)
GCYLQF76_08785(cofH)
CERRGRSB_1810
CEECP3F56_06015(cofH)
KBSEPA93_00450(cofH)
KBBccbrp13_11350(fbiC)
TBHTbon_00585(cofH)
TFLAO0235_13590(cofH)
TTRTter_2623
TROtrd_A0899(cofH) trd_A0900(cofG)
MICAP0L94_12405(cofG)
MJAMJ_1431
MFEMefer_1391
MVUMetvu_0742
MFSMFS40622_0622
MIFMetin_1060
MJHJH146_0555
MESGMLAUSG7_0638(cofH)
MESAMLASG1_0187(cofH)
MIGMetig_1294
MMPMMP0056(cofH) MMP0057(cofH)
MMQMmarC5_1620 MmarC5_1621
MMXMmarC6_0893
MMZMmarC7_1053 MmarC7_1054
MMDGYY_00285 GYY_00290
MMAKMMKA1_00580(cofH) MMKA1_00590(cofH)
MMAOMMOS7_00820(cofH) MMOS7_00830(cofH)
MMADMMJJ_10390(mqnE_1) MMJJ_10400(mqnE_2)
MAEMaeo_0750
MVNMevan_1071 Mevan_1072
MVOMvol_1375
MOKMetok_0201
METFCFE53_02480(cofH)
MTHMTH_820
MMGMTBMA_c12170(cofH)
MWOMWSIV6_1196(cofH)
MTEEMTTB_05630
METCMTCT_0736
METEtca_00787(fbiC_1)
METZMETMT2_0885
METKFVF72_07445(cofH)
MTHMFZP57_05680(cofH)
METJFZP68_00525(cofH)
MSTMsp_0392(cofH)
METBAW729_05100(cofH)
MEISPXD04_05780(cofH)
MRUmru_1266(cofH)
MSIMsm_0079
MEBAbm4_0772(cofH)
MMILsm9_0991(cofH)
MEYETL18_05430(cofH)
MOLYLM1_0639
MAROMarbSA_18830 MarbSA_18880
METVK4897_00820(cofH)
MELMetbo_0140 Metbo_1931
MEWMSWAN_0164 MSWAN_0688
METHMBMB1_0707(cofH1) MBMB1_1031(cofH3)
MFCBRM9_1217(cofH1) BRM9_1488(cofH2)
MFIDSM1535_1898(cofH1) DSM1535_2180(cofH3)
MCUBMCBB_0164(cofH_1) MCBB_0722(cofH_3)
MSUBBK009_01775 BK009_03140
METNBK008_09150 BK008_10855
METTCIT01_01905(cofH) CIT01_08975(cofH)
METOCIT02_01855(cofH) CIT02_03225(cofH)
MEMEHYG87_03440(cofH)
MFEGGCM10025860_17800 GCM10025860_21330
MFVMfer_0690
MKAMK0897(thiH_1)
AFUAF_0798
AFGAFULGI_00008800
APOArcpr_1291
AVEArcve_1610
ASTAsulf_02117
FPLFerp_0003
GACGACE_2059
GAHGAH_00663
MBAMbar_A3416 Mbar_A3417
MBYMSBRM_1567 MSBRM_1568
MBWMSBRW_1317 MSBRW_1318
MBARMSBR2_0841 MSBR2_0842
MBAKMSBR3_1291 MSBR3_1292
MACMA_1489 MA_1490
MMAMM_2495 MM_2496
MMAZMmTuc01_2546
MMJMSMAS_2206 MSMAS_2207
MMACMSMAC_2247 MSMAC_2248
MVCMSVAZ_1511 MSVAZ_1512
MEKMSKOL_1452 MSKOL_1453
MLSMSLAZ_1444 MSLAZ_1445
METMMSMTP_0957 MSMTP_0958
MEFMSWH1_1901 MSWH1_1902
MEQMSWHS_3169 MSWHS_3170
MSJMSSAC_1456 MSSAC_1457
MSZMSSIH_1498 MSSIH_1499
MSWMSSIT_1556 MSSIT_1557
MTHRMSTHT_0213 MSTHT_0214
MTHEMSTHC_0517 MSTHC_0518
MHORMSHOH_2816 MSHOH_2817
MFZAOB57_001355(cofH) AOB57_001360(cofH)
MBUMbur_1303 Mbur_1304
MMETMCMEM_1252 MCMEM_1750 MCMEM_1751
MELOJ7W08_07780(cofH) J7W08_07785(cofH)
MMHMmah_1609 Mmah_1610
MHAZBHR79_05675
MPOTBKM01_01770 BKM01_01775
MEVMetev_0265
MZHMzhil_1605
MPYMpsy_2557 Mpsy_2558
MZIHWN40_09685(cofH)
MMAVRE476_00465(cofH) RE476_00470(cofH)
MSEBRE474_10200(cofH) RE474_10205(cofH)
MHZMetho_0950 Metho_0951
MEHFMmiHf6_10450(fbiC_2)
MEESMmiEs2_00700(fbiC_1)
MTPMthe_0284
MCJMCON_3335(cofH)
MHIMhar_0763
MHUMhun_2410 Mhun_2970
MRTJKHC33_02055(cofH) KHC33_16470(cofH)
MLAMlab_0123
MEMMemar_0047 Memar_0048
MBGBN140_0224(cofH1) BN140_1481(cofH3)
MEMAMMAB1_0286(cofH) MMAB1_1902(cofH)
MCHKMchiMG62_02390
MSUMOH143_07020(cofH) OH143_07030(cofH)
MRCR6Y96_01050(cofH) R6Y96_01055(cofH)
MPIMpet_0331 Mpet_2579
MENDL6E24_06540(cofH)
MEFWF1737_09415(cofH)
MAQERJ40_08105(cofH)
MFKE2N92_07845(cofH)
MOUOU421_04860(cofH) OU421_06495(cofH)
MESBL1S32_09875(cofH)
MANQL1994_05745(cofH) L1994_09265(cofH)
MBNMboo_0038 Mboo_0040
MFOMetfor_0135 Metfor_0137
MESKMETHP_00855
MPLMpal_0050 Mpal_0411
MPDMCP_2456(cofH-1) MCP_2457(cofH-2)
MEZMtc_0997(cofH-1) Mtc_0998(cofH-2)
RCIRCIX459(cofH-2) RCIX460(cofH-1)
HALVNG_1938C
HSLOE_3723R(cofH)
HANRLJ422_07800(cofH)
HDLHALDL1_14670
HHBHhub_3265(cofH)
HAGSJT689_09130(cofH)
HABOJRZ79_07540(cofH)
HNOLT974_13120(cofH)
HLULT972_01715(cofH)
HALHHTSR_1968(cofH)
HHSRHSR6_2043(cofH)
HSUHLASF_1952
HSFHLASA_1938
HAHSHSRCO_2584(thiH2)
SALRFQU85_06460(cofH)
HALREFA46_002145(cofH)
HJEHacjB3_04925
HDOMUK72_01425(cofH)
HALXM0R89_03565(cofH)
HAXZM0R88_03780(cofH)
HAYCNGM10_11460(cofH)
HAXYNGM07_09340(cofH)
SALIL593_13865
SAIMK0C01_04275(cofH)
HARAAArcS_2531(thiH2)
HMArrnAC3278
HHIHAH_0519(cofH)
HHNHISP_02690
HABSG26_10480
HTABVU17_02560
HALJG9465_17525(cofH)
HSINKDQ40_10920(cofH)
NPHNP_2394A(cofH)
NMONmlp_3320(cofH)
NHOHWV23_01195(cofH)
NSALHWV07_16080(cofH)
HUTHuta_1308
HTIHTIA_1198
HALAHrd1104_08980(cofH)
HASVSVXHr_0316(cofH)
HABNHBNXHr_0304(cofH)
HMUHmuk_1418
HALZE5139_10245(cofH)
HALLLC1Hm_0634(cofH)
HAZPGBQ70_10240(cofH)
HALIBV210_12040
HSNDV733_02265
HDSHSR122_0697(thiH2)
HRRHZS55_04965(cofH)
HPELHZS54_05045(cofH)
HLTI7X12_07290(cofH)
HARCHARCEL1_05825
SSAIN0B31_11700(cofH)
HAADMW046_12090(cofH)
HWAHQ_3127A(cofH)
HWCHqrw_3668(cofH)
HVOHVO_2198(cofH)
HALEG3A49_14430(cofH)
HLNSVXHx_2370(cofh)
HMEHFX_2254(thiH)
HGIABY42_11005
HLSKU306_02070(cofH)
HBOHbor_06350
HAQDU484_16980
HAJDU500_00025
HAERDU502_15190(cofH)
HRAEI982_15065(cofH)
HALMFCF25_02470(cofH)
HLAHlac_2018
HALPDOS48_10705
HALBEKH57_14575(cofH)
HEZZEO776_10065(cofH)
HALQHrr1229_009800(cofH)
HSSJ7656_05370(cofH)
HSAIHPS36_10585(cofH)
HAZZKI388_09380(cofH)
SRUBC2R22_17195
HAEhalTADL_3053
HALNB4589_007640(cofH)
HALGHUG10_09405(cofH)
HALUHUG12_06420(cofH)
HMPK6T50_07215(cofH)
HREK6T36_06985(cofH)
HRMK6T25_08820(cofH)
HACBHbl1158_13555(cofH)
HDFAArcSl_2517(cofH)
HAHHalar_2231
HTUHtur_0645
HSALJMJ58_05895(cofH)
HAKZJ0X25_10550(cofH) J0X25_19475(cofH)
NMGNmag_2637(cofH)
HXAHalxa_1693
NATNJ7G_3947
NPENatpe_3133
NVRFEJ81_14745(cofH) FEJ81_22750(cofH)
NPLFGF80_13885(cofH)
NAYHYG81_17945(cofH)
HALYHYG82_19890(cofH)
HJTDVR14_05790
HLOJ0X27_17425(cofH)
NGENatgr_1100
HRUHalru_2256
SAWLNGM29_04345(cofH)
HALVNGM15_13950(cofH) NGM15_17035(cofH)
NOUNatoc_0467
HLRHALLA_06755
HLCCHINAEXTREME01655
NAJB1756_06090
NAGAArcMg_3390
NANAArc1_3296
NARAQQ977_12075(cofH)
NBGDV706_04200
NASGCU68_09425(cofH)
HDABB347_10765
MELUMTLP_05340
MEAMMU439_00990(cofH)
MEAEQEN48_01615(cofH)
NMRNmar_0592
NIRNSED_03095
NKRNKOR_03085
NIDNPIRD3C_1666(cofH)
NINNADRNF5_1569(cofH)
NIWNisw_01900(cofH)
NCLC5F47_06150(cofH)
NOXC5F49_05910(cofH)
NUEC5F50_04480(cofH)
NIPNsoK4_05355(cofH)
NZTNZOSNM25_001398
NCTNMSP_1084(cofH_2)
NICDSQ20_03190(cofH)
NGANgar_c12350(cofH1)
NVNNVIE_011280(cofH1)
NEVNTE_02502
TAANMY3_02529(mqnE_1)
NFNNFRAN_0113(cofH)
NCVNCAV_0880(cofH)
CSYCENSYa_1240
TAHSU86_003155
NIUDSQ19_03440(cofH)
NDVNDEV_0671(cofH)
CCAINAS2_0578
 » show all
Reference
1  [PMID:23072415]
  Authors
Decamps L, Philmus B, Benjdia A, White R, Begley TP, Berteau O
  Title
Biosynthesis of F0, precursor of the F420 cofactor, requires a unique two radical-SAM domain enzyme and tyrosine as substrate.
  Journal
J Am Chem Soc 134:18173-6 (2012)
DOI:10.1021/ja307762b
Reference
2  [PMID:25781338]
  Authors
Philmus B, Decamps L, Berteau O, Begley TP
  Title
Biosynthetic versatility and coordinated action of 5'-deoxyadenosyl radicals in deazaflavin biosynthesis.
  Journal
J Am Chem Soc 137:5406-13 (2015)
DOI:10.1021/ja513287k
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.147
IUBMB Enzyme Nomenclature: 2.5.1.147
ExPASy - ENZYME nomenclature database: 2.5.1.147
BRENDA, the Enzyme Database: 2.5.1.147

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