KEGG ENZYME: 2.5.1.27

ENZYME: 2.5.1.27

Entry

EC 2.5.1.27                 Enzyme

Name

adenylate dimethylallyltransferase (AMP-dependent);
cytokinin synthase (ambiguous);
isopentenyltransferase (ambiguous);
2-isopentenyl-diphosphate:AMP Delta2-isopentenyltransferase;
adenylate isopentenyltransferase (ambiguous);
IPT;
adenylate dimethylallyltransferase;
dimethylallyl-diphosphate:AMP dimethylallyltransferase

Class

Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

Sysname

prenyl-diphosphate:AMP prenyltransferase

Reaction(IUBMB)

prenyl diphosphate + AMP = diphosphate + N6-prenyladenosine 5'-phosphate [RN:R04038]

Reaction(KEGG)

R04038

Substrate

prenyl diphosphate [CPD:C00235];
AMP [CPD:C00020]

Product

diphosphate [CPD:C00013];
N6-prenyladenosine 5'-phosphate [CPD:C04713]

Comment

Involved in the biosynthesis of cytokinins in plants. Some isoforms from the plant Arabidopsis thaliana are specific for AMP while others also have the activity of EC 2.5.1.112, adenylate dimethylallyltransferase (ADP/ATP-dependent).

History

EC 2.5.1.27 created 1984, modified 2002, modified 2013

Pathway

ec00908

Zeatin biosynthesis

ec01110

Biosynthesis of secondary metabolites

Orthology

K10760

adenylate dimethylallyltransferase (cytokinin synthase)

K22871

adenylate dimethylallyltransferase

Genes

PMAX:

117318651

ATH:	AT1G25410(IPT6) AT1G68460(IPT1) AT3G19160(IPT8) AT3G23630(IPT7) AT3G63110(IPT3) AT4G24650(IPT4) AT5G19040(IPT5)

ALY:	9303727 9309993 9314564 9319508 9321363 9324728

CRB:	17880049 17881630 17885744 17893373 17893971 17894591 17899213

CSAT:

104699569 104701473 104705566 104706220 104730983 104735965 104741270 104746867 104748316 104749004 104750663 104756961 104759387 104766279 104767634 104770241 104784266 104787884 104788590 104788646 104788907 104792695

EUS:	EUTSA_v10006499mg EUTSA_v10009876mg EUTSA_v10015859mg EUTSA_v10019632mg EUTSA_v10022241mg EUTSA_v10022249mg EUTSA_v10026816mg

BRP:	103828720 103830971 103837506 103842115 103845790 103851202 103852484 103859798 103862713 117127968

BNA:	106345617 106355091 106356241 106356242 106357100 106357101 106365430 106370472 106370918 106374178 106374850 106377813 106379815 106385487 106385904 106395095 106395535 106409499 106413713 106420240 106431451 106444096 106444949

BOE:	106298696 106298938 106299932 106304865 106309827 106316542 106319832 106325343 106333499 106340154

RSZ:	108810869 108811090 108811091 108814934 108816322 108831384 108832634 108840120 108840416 108852152 108852963 108858886 108859273 108859686

THJ:	104802229 104817551 104820104 104821927 104822228 104822312 104824559

CPAP:

110813518 110819072 110819969 110824206

CIT:	102623172 102624816 102626258 102627215 102631412

CIC:	CICLE_v10005414mg CICLE_v10015747mg CICLE_v10021361mg CICLE_v10025914mg CICLE_v10029953mg

PVY:	116114223 116122022 116125461 116132356 116146309

MINC:

123214025 123217576 123220602 123224541

TCC:	108660727 18602885 18609229 18609940 18609941 18609974 18613391

GRA:	105766147 105778656 105780987 105790749 105793475 105803090 105803213

GHI:	107893329 107897698 107899616 107903869 107912422 107918667 107923176 107949196 107957227 121204743 121219980

GAB:	108460038 108463398 108468494 108472909 108475750 108488804

DZI:	111279863 111283763 111287562 111289035 111307312 111313417

EGR:	104414901 104424863 104427522 104427947 104439813 104439816 104439818 104439819 104439822 104439824 104453788 104454948 104455548

GMX:	100777757 100778430 100779563 100782474 100799145 100799520 100803964 100812928 100813761 100817288 547754(IPT)

GSJ:	114370753 114370884 114374836 114387352 114390202 114392867 114394831 114396048 114397914 114402631 114406840 114420131 114424261

PVU:	PHAVU_001G149400g PHAVU_003G093100g PHAVU_006G154200g PHAVU_007G028100g PHAVU_007G170100g PHAVU_008G005300g

VRA:	106757524 106758528 106768196 106770715 106771461 106775423

VAR:	108319684 108321674 108325195 108325323 108328695 108341364 108342262

VUN:	114164424 114179334 114182920 114187278 114192358 114192462

CCAJ:

109793836 109795018 109806243 109806651 109807406 109816910 109817844

APRC:

113852975 113862126 113870345 113873555 113873643 113874653

MTR:	MTR_1g072540 MTR_1g110590 MTR_2g022140 MTR_2g075100 MTR_3g011590 MTR_3g019820 MTR_3g019900 MTR_3g019930 MTR_3g019980 MTR_3g020100 MTR_3g020155 MTR_3g020740 MTR_3g020760 MTR_4g117330 MTR_6g045287 MTR_6g045293 MTR_7g024250 MTR_7g028880 MTR_7g407170

CAM:	101496203 101496908 101499412 101511214

LJA:	Lj0g3v0154359.1(Lj0g3v0154359.1) Lj4g3v2400530.1(Lj4g3v2400530.1) Lj5g3v0962690.1(Lj5g3v0962690.1) Lj5g3v2183860.1(Lj5g3v2183860.1)

ADU:	107465524 107467295 107475868 107482664 107486884 107492736

AIP:	107617217 107619893 107626050 107638207 107638577 107646203

AHF:	112705443 112712080 112722977 112728401 112741152 112744974 112754834 112758129 112775124 112795845 112798260 112805344

LANG:

109335259 109335368 109337589 109339727 109342514 109347136 109353770 109354536 109357856 109361964

FVE:	101292691 101294272 101295477 101295902 105350247

RCN:	112171809 112172866 112184661 112197816 112198339 112202525

PPER:

18766570 18776356 18791298 18792684

PMUM:

103322847 103329038 103334093 103341494 107880549

PAVI:

110749856 110750473 110759012 110764088 110766135

PDUL:

117613518 117614824 117615577 117628853 117638196

MDM:	103402691 103403839 103432442 103436938 103449027 103451645 103453066

PXB:	103931610 103934169 103940982 103947125 103947564 103947653 103955627 103961092

ZJU:	107404440 107404569 107404570 107423266 107433909 107433912 112492801

MNT:	21393340 21398523 21407760 21409582

CSV:	101204427 101209073 101212201 101215150 101217223 101217256

CMO:	103483750 103488599 103489774 103492689 103497923 107990777

BHJ:	120068268 120076582 120077564 120078569 120082126 120086389 120086859

MCHA:

111007596 111018461

CMAX:

111466978 111467363 111470452 111470933 111472279 111475399 111480109 111486565 111486604 111488830 111489858 111494482 111497849 111499016

CMOS:

111436795 111437772 111443341 111445165 111449909 111455496 111456395 111457751 111460117 111460993 111463593 111464017

CPEP:

111778376 111779083 111779682 111786002 111786246 111787133 111790042 111792726 111800656 111802018 111806355 111806983 111809068 111811102 111811906

RCU:	8266786 8271502 8279533 8279540 8280935

JCU:	105631909 105631956 105642038 105650227

HBR:	110633565 110640842 110647477 110658696 110664998 110665489 110670930

MESC:

110600221 110601521 110602014 110610842 110611851 110616314 110617168

POP:	7461197 7466281 7466894 7479856 7481630 7486764 7497975

PEU:	105113181 105113338 105114734 105116605 105124071 105130823 105132094 105134765

PALZ:

118034536 118039915 118041850 118045644 118060321

JRE:	108979490 108984109 108994970 109005893 109008655 109010913

QSU:	111994109 111998686 111998748 111998775

QLO:	115955987 115970401 115970403 115972330 115994176

TWL:	119982275 119984616 120001720 120007094 120011771 120014990

VVI:	100245931(IPT1) 100247527 100249482 100261184 100854018

VRI:	117910278 117912426 117914155 117917775 117920626

SLY:	100874541(SlIPT1) 100874542(SlIPT2) 100874543(SlIPT4) 101245611 101245726 101246020 101246496 101246596 101251547 101252651 101259193(SlIPT3) 101264142 101265049 101265353 101265662 104644794 109118913 112940050 112940065 112940273 112940274

SPEN:

107003647 107003648 107003649 107003650 107003681 107003683 107003716 107003973 107003974 107003978 107003981 107003992 107013666 107017324 107020035 107027700 107027702 107029782 114073888 114074767 114074769

SOT:	102579012 102595379 102599418 102604151

CANN:

107842013 107845616 107846900 107857008 107874434 107874513

NTA:	107760037 107766196 107781850 107795022 107805874 107811981 107814501 107816040 107818758 107821104

NSY:	104214225 104220386 104228080 104231356 104231357 104231418 104249486

NTO:	104096377 104098434 104098852 104102802 104110738 104118149 104120683

NAU:	109214324 109216970 109227133 109231729 109234959 109236208 109243717 109244780

INI:	109146837 109152289 109152347 109160766(PnIPT1) 109160790 109161265 109161266 109161312 109164724 109167419 109167425 109167428 109191304 109191511(PnIPT2)

ITR:	115996768 116004733 116005189 116015597 116017679 116028965 116028966

SIND:

105156376 105157068 105160874 105162346 105162348 105162351 105162356 105163243 105165356 105171588 105172322 105172326 105179174 105179177 105179790 105179837 105179839 105180048 105180050 105180051 105180052 105180086 105180091 105180094 105180176 105180177 105180256

OEU:	111369488 111369877 111375647 111376556 111381363 111388565 111393432 111396297 111410989

EGT:	105949473 105953418 105954203 105962215 105966018

SSPL:

121747341 121751251 121764038 121767394 121767930 121791723 121793788 121799605 121800333 121802290

HAN:	110884138 110897068 110910273 110915128 110924482 110925784 110927578 110927866 110930685 110930687 110943318

ECAD:

122582908 122592622 122597374 122601231 122607265 122610996

LSV:	111886393 111893033 111894374 111904582 111913731 111913743

CCAV:

112499869 112508072 112513680 112517814 112522373 112528453 112528669

DCR:	108195670 108195679 108198975 108199038 108202067 108206811 108207427 108215448 108220426 108222270

CSIN:

114257665 114270190 114277550 114295006 114302377 114321062

BVG:	104884192 104896430 104898878 104906803

SOE:	110776384 110776590 110798332 110805102

CQI:	110691194 110695030 110710939 110716049 110719118 110721064 110722131

NNU:	104596425 104602154 104602941 104612639

MING:

122066090 122069023 122071993 122091316

TSS:	122647386 122664929 122668250 122668459 122668748 122668749

PSOM:

113294472 113319460 113328032 113345142 113354350 113355300

NCOL:

116261136 116264652 116264783

OSA:	107275347 107275425 107276332 107277295 107278247 4332870 4334529 4339535

DOSA:

Os01t0688300-00(Os01g0688300) Os03t0356900-01(Os03g0356900) Os03t0358900-00(Os03g0358900) Os03t0810100-01(Os03g0810100) Os05t0311801-00(Os05g0311801) Os05t0551700-01(Os05g0551700) Os07t0190150-00(Os07g0190150) Os07t0211700-00(Os07g0211700)

OBR:	102700816 102704691 102721739 102722293 107303714

BDI:	100820995 100821993 100822276 100831164 100833673 100835937 100838252

ATS:	109743451 109761602 109775740 109784495 109787247

TDC:	119268776 119272055 119279428 119281440 119299496 119301589 119303701 119309498 119312383 119332091 119349391 119360800

TAES:

101290601 101290602 101290678 123056848 123058494 123065576 123067418 123101319 123108136 123114770 123117349 123120515 123125875 123144059 123175463 123180738

SBI:	8057086 8068035 8072042 8074559 8075359 8078433

ZMA:	100158226 100158230(IPT4) 103630695 103636191 103644233 103646537 103649047 103651327 103651988

SITA:

101759571 101760010 101762229 101764222 101775321 101776169 101779949 101781905 101782512 111256722

SVS:	117834344 117836933 117846178 117847730 117853491 117855945 117858980 117864685

PVIR:

120643003 120649350 120658725 120662367 120664720 120674728 120675357 120681081 120693420 120695287 120695923 120695965 120697921 120707662 120710604

PHAI:

112876741 112882997 112887399 112892661 112894267 112900674

PDA:	103705113 103708034 103712809 103717091 103718073 120103908 120104567 120104568 120104574 120104575 120112961

EGU:	105034155 105049138 105052792 105057772 105060472

MUS:	103972864 103974113 103978079 103980077 103981583 103981710 103984400 103989539 103994851 103998939

DCT:	110093676 110093677 110111877 110113791 110116586

PEQ:	110025920 110025924 110027775 110030529

AOF:

109848379

ATR:	18432129 18440579

AALT:

CC77DRAFT_1070056

ZTR:	MYCGRDRAFT_107854

DDI:	DDB_G0277215(iptA)

DPP:	DICPUDRAFT_92712(IPTA)

DDQ:

DDI_0145

DIC:	Dpoa569_003578

LBQ:	CKQ53_16075

LPOP:

I6N93_09915

ETP:	LU633_13785

PSTW:

DSJ_22575

XOM:	XOO2787(XOO2787)

XOO:	XOO2936(MiaA)

XOP:

PXO_00142

XOY:	AZ54_09335

XOR:

XOC_2765

XOZ:	BE73_13405

XAL:	XALC_2569(tzs)

XTH:	G4Q83_15815

PPSL:

BJP27_10585

RSO:	RSp1225(tzs)

RSL:	RPSI07_mp1252(tzs)

RSN:	RSPO_m00787(tzs)

RSM:	CMR15_mp20328(tzs)

RSE:

F504_4721

RSY:	RSUY_44080(tzs)

RPU:	CDC45_23775

RSG:	JK151_06715

CCRO:

CMC5_015860

ATU:	Atu6012(ipt) Atu6164(tzs)

ATF:	Ach5_51180(ipt)

AVI:	Avi_8294(ipt)

ARO:	B0909_24365

ALF:	CFBP5473_23870

ARUI:

G6M88_25130 G6M88_25345

NEN:	NCHU2750_55460(ipt) NCHU2750_57020(tzs)

RFA:	A3L23_04945(fas4)

SBH:

SBI_01724

SAQU:

EJC51_41795

SPHV:

F9278_43500

ANA:

all0220

AVA:

Ava_2711

ANN:	EH233_26340

» show all

Reference

1 [PMID:499537]

Authors

Chen CM, Melitz DK.

Title

Cytokinin biosynthesis in a cell-free system from cytokinin-autotrophic tobacco tissue cultures.

Journal

FEBS Lett 107:15-20 (1979)
DOI:10.1016/0014-5793(79)80452-4

Reference

2 [PMID:11313355]

Authors

Takei K, Sakakibara H, Sugiyama T.

Title

Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana.

Journal

J Biol Chem 276:26405-10 (2001)
DOI:10.1074/jbc.M102130200

Sequence

[ath:AT1G68460]

Reference

3 [PMID:15381407]

Authors

Sakano Y, Okada Y, Matsunaga A, Suwama T, Kaneko T, Ito K, Noguchi H, Abe I

Title

Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.).

Journal

Phytochemistry 65:2439-46 (2004)
DOI:10.1016/j.phytochem.2004.08.006

Sequence

[ag:AAS94327]

Other DBs

ExplorEnz - The Enzyme Database:

2.5.1.27

IUBMB Enzyme Nomenclature:

2.5.1.27

ExPASy - ENZYME nomenclature database:

2.5.1.27

BRENDA, the Enzyme Database:

2.5.1.27

CAS:	72840-95-0

DBGET integrated database retrieval system