KEGG   ENZYME: 2.5.1.43
Entry
EC 2.5.1.43                 Enzyme                                 
Name
nicotianamine synthase
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-L-methionine 3-amino-3-carboxypropyltransferase
Reaction(IUBMB)
3 S-adenosyl-L-methionine = 3 S-methyl-5'-thioadenosine + nicotianamine [RN:R00075]
Reaction(KEGG)
R00075
Substrate
S-adenosyl-L-methionine [CPD:C00019]
Product
S-methyl-5'-thioadenosine [CPD:C00170];
nicotianamine [CPD:C05324]
History
EC 2.5.1.43 created 1999
Pathway
ec00270  Cysteine and methionine metabolism
ec00999  Biosynthesis of various plant secondary metabolites
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K05953  nicotianamine synthase
Genes
BCOO119070648
BTAB109044732
ATHAT1G09240(NAS3) AT1G56430(NAS4) AT5G04950(NAS1) AT5G56080(NAS2)
ALY9300505 9309245 9328021 9328557
CRB17877070 17880913 17881818 17896008 17898438
CSAT104701054 104708618 104717596 104730756 104732729 104734502 104739516 104754956 104755112 104758977 104761659 104766177 104767547 104768692 104787782 104789480
EUSEUTSA_v10008206mg EUTSA_v10013812mg EUTSA_v10014123mg EUTSA_v10024166mg EUTSA_v10026750mg
BRP103845041 103847238 103847645 103851850 103855599 103866247 103867728 103871652
BNA106346288 106370283 106379260 106379334 106385040 106412811 106416128 106418370 106428166 106444095 106445243 106453283 111213986 125579103 125587435
BOE106294597 106310962 106315343 106316021 106325609 106327744 106329314
RSZ108816722 108840442 108841297 108843450 108844640 108845407 108850421 108860857 130507416
THJ104811690 104816890 104820632
CPAP110815380 110821244 110826411
CIT102608515 102609096 102609958 102621359
CICCICLE_v10001872mg CICLE_v10010328mg CICLE_v10010369mg CICLE_v10010452mg CICLE_v10010757mg
PVY116106954 116108649 116108744 116108807 116108817 116115971 116115972 116117803
MINC123193914 123206447 123221634
TCC18589241 18600574 18603633
GRA105761119 105767526 105781107 105792468 105793510
GHI107888338 107893879 107894796 107919611 107926213 107927171 107933758 121209352 121217412 121229198
GAB108463453 108468137 108469508 108472923 108485933
HSYR120117544 120124664 120157069 120189659
DZI111277381 111296000 111301967 111307514
EGR104414670 104428248
GMX100775553 100794250 100803630 100814069 100819726
GSJ114367111 114387347 114399003 114407543 114424311
PVUPHAVU_001G225000g PHAVU_005G052500g PHAVU_006G117300g
VRA106754071 106756794 106761843
VAR108328177 108333725 108342357
VUN114186325 114187489 114194913
VUM124829350 124838978 124846082
CCAJ109790589 109797885 109806164
APRC113853087 113856646 113861932
MTR11405947 11412482 25487054 25499657
TPRA123885093 123890199 123890973 123898269
CAM101509924 101510352 101513314 101514194
PSAT127092673 127115345 127132446
VVO131598892 131598893 131598894 131612805 131612807 131615868 131629605
LJALj1g3v4790630.1(Lj1g3v4790630.1) Lj3g3v1048990.1(Lj3g3v1048990.1) Lj6g3v1914550.1(Lj6g3v1914550.1)
ADU107459596 107465178 107492163
AIP107612042 107619807 107645954
AHF112695583 112703449 112710725 112758211 112768963 112779605
LANG109332192 109345844 109353668 109353704 109353753 109354068 109354808
PCIN129306734 129314816 129315568 129317812
QSAO6P43_002874 O6P43_007426 O6P43_011034
FVE101313617 101314050
RCN112180476 112193312
PPER18772486 18790379
PMUM103323493 103344131
PAVI110747490 110762851
PDUL117622689 117631595
MDM103433868 103450853
MSYL126594154 126617673
PXB103930560 103962314
ZJU107418990 125421187
MNT21385396 21405701
CSAV115718660 115718661 115720795 115720829 115721204 115722005
CSV101203651 101209464 101218907 101219339
CMO103492113 103494174 103494189 103494275
BHJ120070769 120071986 120080081 120080591
MCHA111023309 111025239
CMAX111465632 111485338 111486493 111493502
CMOS111430119 111437742 111444226 111450477
CPEP111780548 111785688 111792563 111799305 111804749
RCU8258799 8261713 8261714 8269821
MEAN126669664 126670448 126675397
JCU105635605 105635610 105643528 105647424
HBR110645864 110651885
MESC110600540 110620263 110621562 110623696 110630864 110630877
POP112327508 18098035
PEU105112194 105115144 105135643
PALZ118038804 118046328 118047659 118051673
JRE108981230 108987758 108998835
CILL122316727 122317470 122318255
CAVE132171738
QSU111986344 112028738
QLO115980241 115981763 115981915 115994087
TWL119996994 120006679 120008560 120010986 120013803
VVI100244492 100254544
VRI117924928 117929515
SLY101248619(CHLN)
SPEN107011178
SOT102578513
SSTN125851975
SDUL129884642
CANN107839697
LBB132598441
NTA107762888 107808712(NtNAS1) 107814310 107817799(NtNAS2)
NSY104237053 104249606
NTO104104973 104111414
NAU109223070 109233844
INI109174557 109180988 109182336
ITR116005496 116007614 116025017
SIND105168955 105172429
OEU111385856 111390250 111409892
EGT105954593 105958225
SSPL121754187 121758965 121807355
SMIL131009005 131009460
SHIS125193681 125219049
APAN127257173
HAN110877899 110885610 110890233 110913169 110932790
ECAD122593477 122594208 122596364
LSV111878037 111878402 111878404 111878908
CCAV112503529 112505540
DCR108200806 108210142 108226336
CSIN114279165 114297104
RVL131307468
AEW130750111 130754407 130758937 130775573 130778433 130785706
BVG104890766
SOE110796718
CQI110701176 110736499
ATRI130796950 130817861
MOF131153219 131153625
NNU104598782 104605079
MING122085701 122090294 122091275
TSS122646631 122660360 122669296
PSOM113286440 113286441 113291814 113301249 113306976 113326007 113332641 113333378 113334895 113348128 113348893 113352648 113352966 113352967 113352968 113353597 113353598 113353600 113353604 113354002 113354003 113358139 113359469 113361277
OSA4332607(NAS2) 4332608(NAS1) 4344361(NAS3)
DOSAOs03t0307200-01(Os03g0307200) Os03t0307300-01(Os03g0307300) Os07t0689600-01(Os07g0689600)
OBR102699669 102702270 102715132 121055712
OGL127767494 127767495 127778641
BDI100822873 100826723 100829217 100832895 100845767
ATS109733201 109738215 109738921 109739435 109741827 109748004 109776735 109777780 109779038 109787587 109787589
TDC119285513 119296327 119304374 119314708 119314969 119316430 119316432 119316457 119318492 119323111 119323112 119325023 119326313 119326368 119352811 119352918 119353188 119361851 119361948 119362308
TAES123040191 123043227 123043598 123048357 123051093 123051465 123059244 123083766 123094885 123097678 123099214 123099216 123106176 123106177 123130292 123130501 123130503 123130517 123131325 123131371 123133989 123133995 123135012 123135099 123141357 123141358 123142182 123144159 123146117 123184397 123187039 123187403
TUA125511657 125512992 125513000 125513062 125514551 125514663 125527469 125535178 125535247 125535551 125540768 125549185 125553908 125553909
LPER127295613 127305698 127327535 127331413 127331752 127334576 127336359 127345328
LRD124647583 124662036 124667091 124675918 124676040 124677875 124678417 124687245 124691561 124698080
SBI110435426 8057220 8077509
ZMA100191831 100284978 100285295 103634563 103639224 103643789 109942391 110386945 541637 542480
SITA101770261 101774809 101786975
SVS117840190 117843618
PVIR120652617 120662235 120690551 120694915
PHAI112873937 112876381 112880351
PDA103698830 103700975
EGU105045032 105057353
MUS103968353 103971978 103971979 103985619
ZOF122000908 122003540 122019124 122050754
DCT110105313
PEQ110032766
AOF109835915 109842924 109850903
MSIN131217155 131225701 131256115 131256116 131256331
NCOL116250413 116254804 116262031
ATR18430237 18434693
 » show all
Reference
1
  Authors
Higuchi, K., Kanazawa, K., Nishizawa, N.-K., Chino, M., Mori, S.
  Title
Purification and characterization of nicotianamine synthase from Fe-deficient barley root.
  Journal
Plant Soil 165:173-179 (1994)
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.43
IUBMB Enzyme Nomenclature: 2.5.1.43
ExPASy - ENZYME nomenclature database: 2.5.1.43
BRENDA, the Enzyme Database: 2.5.1.43
CAS: 161515-44-2

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