KEGG   ENZYME: 2.5.1.58
Entry
EC 2.5.1.58                 Enzyme                                 
Name
protein farnesyltransferase;
FTase
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
farnesyl-diphosphate:protein-cysteine farnesyltransferase
Reaction(IUBMB)
farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate [RN:R09844]
Reaction(KEGG)
R09844
Substrate
farnesyl diphosphate [CPD:C00448];
protein-cysteine [CPD:C20119]
Product
S-farnesyl protein [CPD:C20120];
diphosphate [CPD:C00013]
Comment
This enzyme, along with protein geranylgeranyltransferase types I (EC 2.5.1.59) and II (EC 2.5.1.60), constitutes the protein prenyltransferase family of enzymes. Catalyses the formation of a thioether linkage between the C-1 of an isoprenyl group and a cysteine residue fourth from the C-terminus of the protein. These protein acceptors have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably serine, methionine, alanine or glutamine; leucine makes the protein a substrate for EC 2.5.1.59. The enzymes are relaxed in specificity for A1, but cannot act if A2 is aromatic. Substrates of the prenyltransferases include Ras, Rho, Rab, other Ras-related small GTP-binding proteins, gamma-subunits of heterotrimeric G-proteins, nuclear lamins, centromeric proteins and many proteins involved in visual signal transduction. A zinc metalloenzyme that requires Mg2+ for activity.
History
EC 2.5.1.58 created 2003
Pathway
ec00900  Terpenoid backbone biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K05954  protein farnesyltransferase subunit beta
K05955  protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Genes
HSA2339(FNTA) 2342(FNTB)
PTR452971(FNTB) 472929(FNTA)
PPS100991890(FNTB) 103786897(FNTA)
GGO101147861(FNTA) 101150420(FNTB)
PON100436184(FNTB) 100448439(FNTA)
NLE100603548(FNTB) 100605797(FNTA)
MCC708129(FNTB) 712681(FNTA)
MCF101865967(FNTB) 101866500(FNTA)
CSAB103215701(FNTA) 103229180(FNTB)
CATY105582839(FNTB) 105595744(FNTA)
PANU101019526(FNTB) 101024345(FNTA)
TGE112628928(FNTB) 112629727(FNTA)
RRO104668310(FNTA) 104678437(FNTB)
RBB108542421(FNTB)
TFN117069465(FNTB) 117095876(FNTA)
PTEH111544166(FNTA) 111555921(FNTB)
CJC100392598(FNTB) 100401677(FNTA)
SBQ101053282(FNTB) 104649982(FNTA)
CSYR103262249(FNTA) 103272996(FNTB)
MMUR105878133(FNTA) 105878351
OGA100943586(FNTB) 100951363(FNTA)
MMU110606(Fntb) 14272(Fnta)
MCAL110299877(Fnta) 110306655(Fntb)
MPAH110324339(Fntb) 110336524(Fnta)
RNO25318(Fnta) 64511(Fntb)
MCOC116069073(Fnta) 116080961(Fntb)
MUN110547757 110566308(Fnta)
CGE100752221(Fntb) 100752295(Fnta)
PLEU114681353(Fnta) 114682548 114697749(Fntb)
NGI103749278(Fntb)
HGL101703640(Fnta) 101703774(Fntb)
CPOC100718610(Fnta) 100718688(Fntb)
CCAN109691132(Fntb) 109699820(Fnta)
DORD105985255 105993606(Fnta)
DSP122107673(Fnta) 122117965(Fntb)
OCU100341143 100343931(FNTB) 100347188(FNTA)
OPI101525746(FNTB) 101535950(FNTA)
TUP102479775(FNTB) 102494685(FNTA)
CFA475566(FNTA) 490735(FNTB)
VVP112916168(FNTA) 112927169(FNTB)
VLG121489954(FNTA) 121492883
AML100467230(FNTA) 100474526(FNTB) 105240778
UMR103674342 103677044(FNTA)
UAH113245570(FNTA) 113246287 113246325
UAR123780314(FNTA) 123800736
ELK111144545 111158098
LLV125086386 125092813 125093202 125103717 125103795
MPUF101680717(FNTB) 101690550(FNTA)
ORO101376890(FNTA) 101383702(FNTB) 101383786
EJU114218957(FNTB) 114219148 114224831(FNTA)
ZCA113908809 113912729 113925136(FNTA)
MLX118002294 118009909(FNTA)
FCA101088759(FNTB) 101097062(FNTA)
PYU121010952(FNTA) 121031903(FNTB)
PBG122469217(FNTB) 122472840(FNTA)
PTG102957564(FNTA) 102966415(FNTB)
PPAD109262249(FNTA) 109268319
AJU106971334(FNTB) 106990022(FNTA)
HHV120234020(FNTA) 120238402(FNTB)
BTA281169(FNTA) 327686(FNTB)
BOM102272299(FNTA) 102287965(FNTB)
BIU109553498(FNTA) 109565251(FNTB)
BBUB102403968(FNTA) 102408492(FNTB)
CHX102189488(FNTB) 102191016(FNTA)
OAS100302086(FNTA) 101110335(FNTB)
ODA120852822 120858665 120865867(FNTA)
CCAD122432460(FNTA) 122443757(FNTB)
SSC100512293(FNTB) 100627556(FNTA)
CFR102511020(FNTA) 102522965(FNTB)
CBAI105071090(FNTA) 105074677(FNTB)
CDK105086183(FNTB) 105094300(FNTA)
VPC102524798(FNTB) 102526086(FNTA)
BACU102999003(FNTB) 103014092(FNTA)
LVE103074104(FNTB) 103085981(FNTA)
OOR101277224(FNTB) 101288631(FNTA)
DLE111173060 111173563(FNTA)
PCAD102973180(FNTA) 102990655(FNTB)
PSIU116746809(FNTA) 116749054(FNTB)
ECB100052486(FNTB) 100053704(FNTA)
EPZ103541355(FNTA) 103550215(FNTB)
EAI106828969(FNTA) 106844888(FNTB)
MYB102255519(FNTA) 102261986(FNTB)
MYD102751880(FNTB) 102770189(FNTA)
MMYO118650290(FNTA) 118656482(FNTB) 118677058
MLF102422381(FNTB) 102424327(FNTA)
MNA107523930(FNTA) 107545681
PKL118716640 118729221(FNTA)
HAI109382065 109386282(FNTA)
DRO112312008(FNTB) 112321491(FNTA)
SHON118976738 118993221(FNTA)
AJM119034781 119059390 119063070(FNTA)
PDIC114491366(FNTB) 114508683(FNTA)
PHAS123807507(FNTA) 123808650(FNTB)
MMF118622858(FNTA) 118625775(FNTB)
RFQ117021605(FNTA) 117022983(FNTB)
PALE102881721(FNTB) 102890666(FNTA)
PGIG120595451(FNTA) 120612748(FNTB)
PVP105300643(FNTA) 105308396
RAY107501360(FNTA) 107509310
MJV108396030(FNTA) 108406933
TOD119239190(FNTB) 119257863(FNTA)
SARA101537908(FNTA) 101555126
LAV100655632(FNTB) 100669104(FNTA)
TMU101353464 101353928
DNM101411030(FNTA) 101418157(FNTB) 101443224
MDO100027938(FNTB) 100617990(FNTA)
GAS123232361 123234843(FNTA) 123237732 123246623
SHR100916157(FNTB) 100924354(FNTA)
PCW110196382(FNTA) 110220602(FNTB)
OAA100078580(FNTA) 114812144(FNTB)
GGA100857683(FNTB) 427299(FNTA)
PCOC116237858 116241709(FNTA)
MGP100544213(FNTA) 100548337
CJO107306423 107314159
NMEL110390019(FNTA) 110401482
APLA101793836(FNTA) 110354396
ACYG106040419(FNTA)
AFUL116490156 116500856(FNTA)
TGU100222812(FNTA) 100223864
LSR110472793(FNTA) 110485005
SCAN103821233(FNTA) 103822168
PMOA120503647 120509478(FNTA)
OTC121331494(FNTA) 121336792
PRUF121352334 121355676(FNTA)
GFR102031891(FNTA) 102043195(FNTB)
FAB101810421(FNTB) 101814503(FNTA)
PHI102102894(FNTB) 102111175(FNTA)
PMAJ107198168(FNTA) 107205595
CCAE111940897(FNTA) 111945042
CCW104689741(FNTA) 104693013
ETL114064978(FNTA) 114067960
ZAB102070147 102075236(FNTA)
FPG101913248(FNTA) 101920206(FNTB)
FCH102046284(FNTA) 102052180 102059349
CLV102095984 102098098
EGZ104126429(FNTA)
NNI104017579(FNTA) 104020564
ACUN113481054 113490035(FNTA)
TALA104365298(FNTA) 116962512
PADL103923240(FNTA)
ACHC115336467(FNTA) 115338445
AAM106482499 106487919 106487920
AROW112971677 112972297(FNTA)
NPD112954043 112956423(FNTA)
DNE112982251(FNTA) 112993459
ASN102382443(FNTA) 102385137
AMJ102564152(FNTA) 102574457(FNTB)
CPOO109318231 109323586
GGN109297398
PSS102452430(FNTA) 102459340
CMY102937672 102940529(FNTA)
CPIC101934158(FNTA) 101938834
TST117873112 117879098(FNTA)
CABI116822203 116824769(FNTA)
MRV120404041 120407579(FNTA)
ACS100559827 100561851(fnta)
PVT110083168(FNTA) 110085642
SUND121919833 121923240(FNTA)
PBI103049019 103051193(FNTA)
PMUR107289674(FNTA) 107295132
TSR106538907 106556953(FNTA)
PGUT117661638(FNTA) 117675319
VKO123027397 123030203(FNTA)
PMUA114587722(FNTA) 114602281
ZVI118075226(FNTA) 118090410
GJA107120943(FNTA) 107121947
XLA100137632(fnta.S) 108699724(fntb.S) 447605(fntb.L)
XTR100144648(fnta) 550012(fntb)
NPR108796770 108804918(FNTA)
RTEM120914553(FNTA) 120920963
BBUF120982194 120989666(FNTA)
BGAR122922182 122927353(FNTA)
DRE323500(fntb) 555882(fnta)
SRX107710485 107715177 107721314 107756604
SANH107668263 107671778 107676163 107678656
SGH107549080 107556846 107589126 107602629
CCAR109062179 109082285 109090484
CAUA113047820 113063073 113113795 113120886
IPU108257588(fntb) 108268629(fnta)
PHYP113529365(fnta) 113531985
SMEO124376993(fntb) 124386551(fnta)
AMEX103026998(fnta) 103033540
EEE113570149 113582062(fnta)
TRU101076206(fnta) 101079983
TNGGSTEN00011516G001 GSTEN00030423G001
LCO104926712 109141898(fnta)
NCC104949856
CGOB115014496(fnta) 115028758
ELY117260641(fnta) 117271286(fntb)
PLEP121948135(fnta) 121956004(fntb)
SLUC116036577(fnta) 116065981(fntb)
ECRA117952179(fnta) 117961679(fntb)
PFLV114562775(fnta) 114572762
GAT120807709(fntb) 120818454(fnta)
PPUG119194902(fntb) 119210776(fnta)
MSAM119889073(fnta) 119908497(fntb)
CUD121516007(fnta) 121520909(fntb)
MZE101468735(fnta) 101479885
ONL100705878(fnta) 100709246
OAU116312757(fntb) 116329444(fnta)
OLA101160126 101160920(fnta)
OML112153760(fnta) 112158416(fntb)
XMA102234643(fnta) 102235994
XCO114139528(fnta) 114159014
XHE116713955(fnta) 116734564
PRET103457641 103471041(fnta)
PFOR103130771 103149281(fnta)
PLAI106952411(fnta) 106960880
PMEI106921462(fnta) 106932454
GAF122824898(fntb) 122837223(fnta)
CVG107090164(fnta) 107093655
CTUL119778409(fnta) 119785644(fntb)
GMU124859761(fnta) 124882298(fntb)
NFU107377823 107381432(fnta)
KMR108228747(fnta) 108233508(fntb)
ALIM106518960(fnta) 106522425
NWH119409173(fnta) 119418599(fntb)
AOCE111567609 111569570 111572193
CSEM103381205 103391301(fnta)
POV109625378(fnta) 109636082
SSEN122778897(fnta) 122783807(fntb)
HHIP117758531(fntb) 117769091(fnta)
LCF108878782(fnta) 108887265
SDU111216443 111226657(fnta)
SLAL111646521(fnta) 111661543
XGL120784877(fnta) 120789417(fntb)
HCQ109515791(fnta) 109523733
BPEC110159349 110166430(fnta)
MALB109957583(fnta) 109962295
SASA106571088 106604549 106608156 106611536
OTW112221076 112256360 121846477(fntb)
OMY110488956 110505155 110529174(fntb)
OGO123990500(fntb) 123993531 124011313
ONE115115079 115129572 115130838
SALP111965854 111968202 112070172 112071854 112073675
SNH120048018 120060155(fntb) 120062234
ELS105006791(fnta) 105024336
SFM108919508 108938728(fnta)
PKI111835548(fnta) 111838904
AANG118207535 118209717(fnta) 118229681(fntb)
LOC102684798 102695133(fnta)
PSPA121323495(fnta) 121324820 121329662
ARUT117408744 117419499 117420607 117421913
LCM102349666(FNTA) 102350945(FNTB)
CMK103175221(fntb) 103191504(fnta)
RTP109925387 109935285(fnta)
BFO118412954 118421077
BBEL109471499 109482783
SCLV120327200 120329065
SPU576777 578890
APLC110983352 110987154
SKO100378820 100378865
DMEDmel_CG17565(CG17565) Dmel_CG2976(Fnta)
DER6543507 6553352
DSE6613382 6616886
DSIDsimw501_GD19096(Dsim_GD19096) Dsimw501_GD22689(Dsim_GD22689)
DYADyak_GE14673 Dyak_GE24394
DAN6497242 6501268
DSR110177356 110179159
DPODpse_GA14558 Dpse_GA15551
DPE6588913 6592031
DMN108155100 108163173
DWI6644134 6651543
DGR6561499 6564055
DMODmoj_GI16973 Dmoj_GI22551
DAZ108608835 108611994
DNV108650017 108653088
DHE111599344 111604840
DVI6628506 6629511
CCAT101454406 101463210
BOD106614942 106627682
MDE101896825 101897722
SCAC106084859 106087684
LCQ111676538 111680641
AGAAgaP_AGAP001729 AgaP_AGAP011767
ACOZ120951415 120958336
AARA120895810 120903672
AAG5564364 5565594
AALB109408764 109411504 109415925 109432704
CQUCpipJ_CPIJ000805 CpipJ_CPIJ011400
CPII120430842 120431860
CNS116347568
AME102656263 551732
ACER107992405 108000294
ALAB122712807 122715841
BIM100743778 100746668
BBIF117208581 117209940
BVK117230877 117238406
BVAN117159112 117166466
BTER100644280 100648031
BPYO122567132 122576037
CCAL108628820 108632140
OBB114873072 114879669
MGEN117218544 117219622 117219623
NMEA116431456 116431940
CGIG122398724 122398741 122405524
SOC105194675 105200351
MPHA105834524 105838194
AEC105143939 105154885
ACEP105620515 105625892
PBAR105425081 105428885
VEM105568003 105569045
HST105181982 105188016 112589840
DQU106748502 106750669
CFO105250428 105254323
FEX115241458 115245709
LHU105671601 105676870
PGC109854492 109859262
OBO105277666 105281700
PCF106784296 106790424
PFUC122521543 122523495
VPS122629624 122638019
NVI100123894 116417632
CSOL105362354 105363667
TPRE106651537 106651554
MDL103573411 103580607
CGLO123263688 123270626
FAS105266917 105271177
DAM107040672 107048416
AGIF122848434 122848828
CCIN107273070 107274116 107275022
TCA659329 661918
DPA109539749 109546132
SOY115874059 115876888
ATD109594364 109594856
CSET123307967 123315404
AGB108906521 108909167
LDC111504477 111506917
NVL108564375 108566731
APLN108739974 108744450
PPYR116164659 116171473
OTU111424560 111428475
BMOR692501 692537
BMAN114245613 114245617 114245820
MSEX115444022 115451525
DPLKGM_202269 KGM_203747
BANY112044288 112045679
PMAC106713859 106721521
PPOT106101111 106103046
PXU106120240 106121920
PRAP110997457 110998297
ZCE119828640 119833901
HAW110373406 110383240
TNL113498340 113504766
OFU114350178 114352746
PXY105382376 105392536
API100166879 100167417(Fnta)
DNX107172137 107173587
AGS114125211 114130403
RMD113555957 113560402
BTAB109043710 109044375
DCI103511525 103517803
CLEC106665237 106670966
HHAL106682887 106692644
NLU111047958 111059320 120351005 120356367
PHUPhum_PHUM420660 Phum_PHUM459460
FOC113203253 113206670
ZNE110836157 110839370
CSEC111865671 111868695
FCD110845875 110856750
DPXDAPPUDRAFT_194107 DAPPUDRAFT_209281
DMK116916055 116917760
PVM113823046
PJA122244754 122245186 122257761
HAME121856219 121868717
PCLA123772395 123772985
PTRU123510057 123512358
HAZT108669691 108682172
EAF111696450 111696687
ISCIscW_ISCW017213 IscW_ISCW018919
DSV119453949 119458094
RSAN119374283 119399282
RMP119167483 119181181
VDE111246449 111248052
VJA111262685 111262984
TUT107361832 107371809
DPTE113791043 113793583
DFR124491495 124497953
CSCU111626239 111640882
PTEP107441621 107448242
SDM118196093 118196822
CELCELE_F23B12.6(fntb-1) CELE_R02D3.5(fnta-1)
CBRCBG_01666 CBG_04611(Cbr-tag-114)
BMYBM_BM13710(Bma-fntb-1) BM_BM13738(Bma-fnta-1)
LOALOAG_01284 LOAG_17424
NAINECAME_03729
TSPTsp_01343 Tsp_08562 Tsp_12506a
HROHELRODRAFT_110647 HELRODRAFT_185749
LGILOTGIDRAFT_201479 LOTGIDRAFT_222587
PCAN112563576 112570052
BGT106069690 106071577
GAE121370957 121382556
HRF124141973 124143389
HRJ124280088 124284089
CRG105331136 105343103 117685575
MYI110441901 110455386 110457043
PMAX117323475 117339444
MMER123530009 123547387
OBI106867415 106879051
OSN115212343 115223203
LAK106153672 106156335
SMMSmp_065780 Smp_091770
SHXMS3_0020534
OVIT265_03082 T265_06277
EGLEGR_02831 EGR_07671
NVE5517875 5521432
EPA110232498 110243655
ATEN116302995 116308426
ADF107335525
AMIL114947047 114951204
PDAM113668511 113677081
SPIS111325145 111328352
DGT114515817 114531662
XEN124444961 124452667
HMG100199701 100210265
TADTRIADDRAFT_29686 TRIADDRAFT_32965
AQU100635380 100638673
ATHAT3G59380(FTA) AT5G40280(ERA1)
ALY110226330 9314337
CRB17880934 17885789
CSAT104699500 104699974 104719661 104724361 104732806 104749418 104788180
EUSEUTSA_v10025709mg EUTSA_v10027764mg
BRP103863970 103864229 103870807
BNA106352548 106380632 106385767 106402436 106446141 106454449
BOE106322984 106337353
RSZ108816471 108848594
THJ104803670 104805397
CPAP110816251 110816345
CIT102617661 102620973
CICCICLE_v10015290mg CICLE_v10021008mg
PVY116115121 116123639
MINC123195471 123206025 123207456 123207742 123207926 123221937 123222534
TCC18600750 18603783
GRA105770666 105798312
GHI107888645 107892292 107904382 121217939
GAB108453116 108487072
DZI111280056 111292433 111306992 111316638
EGR104419274 104433178 104450953 104451622
GMX100306703(ERA1B) 100790130 100811502 100814543(ERA1A)
GSJ114373502 114376009 114386333 114416479
PVUPHAVU_004G014500g PHAVU_005G152400g
VRA106767338 106778445
VAR108332340 108343850
VUN114182673 114186023
CCAJ109788827 109805895
APRC113853848 113867492
MTRMTR_2g098650 MTR_6g007165
CAM101501751 101511370
LJALj0g3v0089459.1(Lj0g3v0089459.1) Lj2g3v1014160.1(Lj2g3v1014160.1)
ADU107461489 107462171
AIP107613569 107644030
AHF112706610 112707122 112750798 112771678 112802464
LANG109341002 109341015 109342939
FVE101293216 101314529
RCN112190127 112197549
PPER109947641 18782183
PMUM103318855 103322403 103329871
PAVI110754256 110758558 110760044
PDUL117615559 117621468 117630985
MDM103404346 103429024 103432715
PXB103936243 103953612 103963949
ZJU107415381 107421848
MNT21403390 21407401
CSV101212104 101213752
CMO103487088 103494543
BHJ120087890 120089773
MCHA111014704 111025377
CMAX111479431 111481524
CMOS111441906 111457674
CPEP111790580 111790652
RCU8266391 8269307
JCU105629228 105641740
HBR110645010 110647353 110652629 110657017 110657557
MESC110603855 110605314 110605316 110613490
POP18107281 7491765
PEU105117053 105127018
PALZ118032070 118058272
JRE108980046 108992807
QSU111987646 111993524 111996298 112014889 112033754
QLO115963191 115976671
TWL119989216 120011561
VVI100247502 100266301
VRI117914400 117930344
SLY544036(FTA) 544037(FTB)
SPEN107008797 107021133
SOT102589815 102593792
CANN107860637 107875743
NTA107777651 107798306 107814428(Ntalpha) 107827532(NtbetaF)
NSY104210829 104230207
NTO104085976 104103977
NAU109206883 109213567
INI109161940 109178319
ITR116018978 116020958
SIND105172358 105172359 105177137
OEU111396929 111409583
EGT105956244 105969251
SSPL121775168 121776290 121804521 121809933
HAN110867580 110868635
ECAD122605473 122609598
LSV111876435 111876515 111891252
CCAV112521988 112529162
DCR108206860 108219387
CSIN114284046 114285878
BVG104888775 104906039
SOE110777583 110789101
CQI110686821 110688461 110689264 110718300
NNU104587019 104587193
MING122076889 122083826
TSS122657067 122667210
PSOM113276436 113282400 113316854 113329471
NCOL116248626 116260174
OSA4327880 4347566
DOSAOs09t0514400-01(Os09g0514400)
OBR102705494 102709026
BDI100830567 100845294
ATS109744376 109773598 109778677
TDC119268914 119279619 119302288 119309852 119311114
TAES100127062 123061975 123079088 123104391 123112677 123114911 123120739 123120955 123122168 123125153 123176585
SBI8054810 8062157
ZMA100272584 100273635
SITA101755480 101777190
SVS117845435 117858896
PVIR120661224 120672284 120675169 120683837 120707968
PHAI112880696 112895850
PDA103715282 103722105 120106532
EGU105034304 105038116 105047140 105047991
MUS103969298 103978359 103996150
DCT110104042 110110010 110110255
PEQ110028754 110032538
AOF109837606 109837776
ATR18434837 18448558
SMOSELMODRAFT_228081 SELMODRAFT_228128 SELMODRAFT_232856 SELMODRAFT_233552
PPP112286658 112291220
CRECHLRE_01g016950v5 CHLRE_14g612500v5
VCNVOLCADRAFT_107343 VOLCADRAFT_85812
MNGMNEG_5015
CSLCOCSUDRAFT_17363 COCSUDRAFT_29686
CVRCHLNCDRAFT_28585 CHLNCDRAFT_37079
APROF751_3684 F751_5631
OLUOSTLU_26200 OSTLU_86397
OTAOT_ostta02g03570 OT_ostta10g02435
BPGBathy03g02240
MISMICPUN_70506 MICPUN_81968
MPPMICPUCDRAFT_23673 MICPUCDRAFT_2945
CMECYME_CML138C CYME_CMS122C
GSLGasu_14150 Gasu_19270
CCPCHC_T00003240001 CHC_T00003446001
SCEYDL090C(RAM1) YKL019W(RAM2)
AGOAGOS_ACR094C AGOS_ADR275W
ERCEcym_3385 Ecym_5611
KLAKLLA0_E17975g KLLA0_F07161g
KMXKLMA_20389(RAM1) KLMA_60145(RAM2)
LTHKLTH0C00660g KLTH0F10340g
VPOKpol_1043p8 Kpol_1057p11
ZROZYRO0A07898g ZYRO0D00660g
CGRCAGL0L07106g CAGL0L09801g
NCSNCAS_0B05820(NCAS0B05820) NCAS_0H03470(NCAS0H03470)
NDINDAI_0B03130(NDAI0B03130) NDAI_0C00210(NDAI0C00210)
TPFTPHA_0C03780(TPHA0C03780) TPHA_0N01840(TPHA0N01840)
TBLTBLA_0A00700(TBLA0A00700) TBLA_0B09490(TBLA0B09490)
TDLTDEL_0B07560(TDEL0B07560) TDEL_0G02960(TDEL0G02960)
TGBHG536_0A02950 HG536_0G00230
KAFKAFR_0A06950(KAFR0A06950) KAFR_0C03850(KAFR0C03850)
ZMKHG535_0D01220 HG535_0H00250
PPAPAS_chr1-3_0192 PAS_chr3_0636
DHADEHA2F11022g DEHA2G16918g
PICPICST_55783(RAM2) PICST_82404(RAM1)
PGUPGUG_04045 PGUG_04528
SPAASPAPADRAFT_131635 SPAPADRAFT_142820
LELLELG_00427 LELG_04546
CALCAALFM_C109530WA(RAM2) CAALFM_C403900CA(RAM1)
CTPCTRG_00312 CTRG_03407
COTCORT_0A05300 CORT_0B03140
CDUCD36_08990 CD36_43630
CTENCANTEDRAFT_116652 CANTEDRAFT_97171
YLIYALI0B16126g YALI0D14762g
CLUCLUG_03869 CLUG_05520
CLUSA9F13_01g02662 A9F13_16g00693
CAURCJI97_000306 CJI97_005612
SLBAWJ20_185(RAM2) AWJ20_887(RAM1)
PKZC5L36_0C03490 C5L36_0C04570
BNNFOA43_002517 FOA43_002628
BBRXBRETT_000068 BRETT_000197
NCRNCU03632 NCU05999
NTENEUTE1DRAFT144524(NEUTE1DRAFT_144524) NEUTE1DRAFT88206(NEUTE1DRAFT_88206)
SMPSMAC_03092 SMAC_07927
PANPODANSg3085 PODANSg8778
TTTTHITE_2109960 THITE_39903
MTMMYCTH_2300958 MYCTH_2306596
CTHRCTHT_0042280 CTHT_0065490
MGRMGG_01287 MGG_16220
TMNUCRPA7_6956
SSCKSPSK_05151 SPSK_05989
FGRFGSG_05911 FGSG_08771
FPUFPSE_03068 FPSE_10042
FVRFVEG_01886 FVEG_04522
FOXFOXG_03028 FOXG_07593
NHENECHADRAFT_35834 NECHADRAFT_49141
TRETRIREDRAFT_109078 TRIREDRAFT_22093
TRRM419DRAFT_100822 M419DRAFT_140969
MAWMAC_02644 MAC_06013
MAJMAA_02158 MAA_06143
CMTCCM_05066 CCM_07935
PLJVFPFJ_02822 VFPFJ_10820
VALVDBG_03368 VDBG_08024
VDAVDAG_05598 VDAG_09974
CFJCFIO01_10536 CFIO01_12204
SAPOSAPIO_CDS10493 SAPIO_CDS8150
ELAUCREL1_3997
PFYPFICI_12069 PFICI_14185
SSLSS1G_00169 SS1G_06080
BFUBCIN_03g06350(Bcram1) BCIN_05g03760
MBEMBM_01045 MBM_07807
PSCOLY89DRAFT_576435 LY89DRAFT_588064
GLZGLAREA_00453 GLAREA_02940
ANIAN2002.2 AN3867.2
AFMAFUA_4G07800 AFUA_4G10330
ACTACLA_047170 ACLA_049530
NFINFIA_105740 NFIA_108370
AORAO090003001188 AO090023000791
ANGANI_1_1988184(An04g06620) ANI_1_462184(An04g02210)
AFVAFLA_000479 AFLA_007137
ALUCAKAW2_30334S(RAM1) AKAW2_51251S(RAM2)
ACHEACHE_10756A(RAM1) ACHE_70801A(RAM2)
APUUAPUU_21050A(RAM1) APUU_40526A(RAM2)
PCSPc13g07290 Pc22g12410
PDPPDIP_16250
TMFPMAA_040340 PMAA_094380
TRGTRUGW13939_02738 TRUGW13939_09879
CIMCIMG_05727 CIMG_12864(CIMG00563)
CPWCPC735_019440 CPC735_056760
UREUREG_00585 UREG_04740
PBLPAAG_07086
PBNPADG_01610 PADG_04113
ABEARB_01090 ARB_03728
TVETRV_02860 TRV_06247
AJEHCAG_04241 HCAG_06093
BGHBDBG_01859 BDBG_02303
PNOSNOG_03798 SNOG_06663
PTEPTT_05307 PTT_14555
BZECOCCADRAFT_6868 COCCADRAFT_82711
BSCCOCSADRAFT_173531 COCSADRAFT_33087
BORCOCMIDRAFT_105216 COCMIDRAFT_95956
AALTCC77DRAFT_843724 CC77DRAFT_935191
ZTRMYCGRDRAFT_69467 MYCGRDRAFT_73812
PFJMYCFIDRAFT_78077 MYCFIDRAFT_98333
BCOMBAUCODRAFT_326503 BAUCODRAFT_403486
NPAUCRNP2_2026 UCRNP2_2132
TMLGSTUM_00001514001 GSTUM_00007324001
SPOSPAC17G6.04c(cpp1) SPAPB1A10.04c(cwp1)
CNECNE03110 CNF02370
CNBCNBE3110 CNBF2330
CGICGB_E4110W CGB_F3420C
TMSTREMEDRAFT_57242 TREMEDRAFT_74941
TASAA1Q1_04595 A1Q1_06791
TVSTRAVEDRAFT_135718 TRAVEDRAFT_30914
DSQDICSQDRAFT_85477 DICSQDRAFT_88928
PCOPHACADRAFT_212873 PHACADRAFT_251373
SHSSTEHIDRAFT_166939 STEHIDRAFT_79483
HIRHETIRDRAFT_325323 HETIRDRAFT_478327
PSQPUNSTDRAFT_114041 PUNSTDRAFT_121677
ADLAURDEDRAFT_111856 AURDEDRAFT_182126
FMEFOMMEDRAFT_113019 FOMMEDRAFT_143336
GTRGLOTRDRAFT_139894 GLOTRDRAFT_80586
LBCLACBIDRAFT_178594 LACBIDRAFT_191455 LACBIDRAFT_191458 LACBIDRAFT_253023
MPRMPER_08954
MRRMoror_1096 Moror_4989
CCICC1G_05578 CC1G_07486
SCMSCHCODRAFT_68620 SCHCODRAFT_83386
ABPAGABI1DRAFT115274(AGABI1DRAFT_115274) AGABI1DRAFT61805(AGABI1DRAFT_61805)
ABVAGABI2DRAFT194236(AGABI2DRAFT_194236) AGABI2DRAFT210804(AGABI2DRAFT_210804)
CPUTCONPUDRAFT_127885 CONPUDRAFT_157249
SLASERLADRAFT_433805 SERLADRAFT_450894
WSEWALSEDRAFT_44367 WALSEDRAFT_60563
WICJ056_000119 J056_004663
UMAUMAG_05348 UMAG_11672
PFPPFL1_01980 PFL1_05389
MGLMGL_3801
MRTMRET_0119 MRET_0605
MSYMMSY001_1834
PGRPGTG_07083 PGTG_15593 PGTG_15594 PGTG_19767 PGTG_19768
MLRMELLADRAFT_26326 MELLADRAFT_26510 MELLADRAFT_26531 MELLADRAFT_32910 MELLADRAFT_33476 MELLADRAFT_38891 MELLADRAFT_41054
MBRMONBRDRAFT_29023 MONBRDRAFT_33884
SREPTSG_04176 PTSG_07310
DDIDDB_G0270948(fntB) DDB_G0283053(fntA)
DPPDICPUDRAFT_28303 DICPUDRAFT_41593 DICPUDRAFT_75786
DFADFA_05584(fntA) DFA_10414(fntB)
EHIEHI_006190(83.t00031) EHI_074760(288.t00007)
EDIEDI_044760 EDI_198980
EIVEIN_056290 EIN_489710
ACANACA1_064640 ACA1_245060
PFAPF3D7_1147500
PFDPFDG_01874
PFHPFHG_01534
PREIPRSY57_1145800
PYOPY17X_0903000
PCBPCHAS_070280
PBEPBANKA_0901600
PVVPVVCY_0904570
PKNPKNH_0945400
PVXPVX_092960 PVX_101030
PCYPCYB_095270
TANTA15255 TA17870
TPVTP02_0810
TOTTOT_020000747 TOT_030000161
BEQBEWA_027850 BEWA_052690
BBOBBOV_III002550(17.m07246) BBOV_III004550(17.m07408)
BMICBMR1_02g01605 BmR1_04g08860
BBIGBBBOND_0304100 BBBOND_0310410
CPVcgd1_1980 cgd6_2510
CHOChro.10227 Chro.60290
TGOTGME49_200370
TETTTHERM_00248530 TTHERM_00532030
PTMGSPATT00009156001 GSPATT00018136001 GSPATT00029013001
SMINv1.2.028464.t1(symbB.v1.2.028464.t1)
PTIPHATRDRAFT_16932 PHATRDRAFT_45841
FCYFRACYDRAFT_159653 FRACYDRAFT_193048
TPSTHAPSDRAFT_264607 THAPSDRAFT_268577(GGTA1)
NGDNGA_0546400
AAFAURANDRAFT_24404 AURANDRAFT_4335
PIFPITG_11142 PITG_16071
PSOJPHYSODRAFT_350539 PHYSODRAFT_556892
SPARSPRG_00725 SPRG_05623 SPRG_18431
EHXEMIHUDRAFT_197718 EMIHUDRAFT_54874 EMIHUDRAFT_61152
GTTGUITHDRAFT_142121
TBRTb927.3.4490 Tb927.7.460
TBGTbgDal_III4930 TbgDal_VII310
TCR507257.70 510329.280
LMALMJF_26_1470 LMJF_29_1950
LIFLINJ_26_1450 LINJ_29_2070
LDOLDBPK_261450 LDBPK_292070
LMILMXM_08_29_1950 LMXM_26_1470
LBZLBRM_26_1490 LBRM_29_1920
LPANLPMP_261450 LPMP_291960
NGRNAEGRDRAFT_2982 NAEGRDRAFT_35542
TVATVAG_021630 TVAG_151840 TVAG_190520 TVAG_230550 TVAG_257590 TVAG_338240 TVAG_366000 TVAG_434060 TVAG_462400 TVAG_464130
GLAGL50803_0015820 GL50803_009382
 » show all
Reference
1  [PMID:7756316]
  Authors
Furfine ES, Leban JJ, Landavazo A, Moomaw JF, Casey PJ.
  Title
Protein farnesyltransferase: kinetics of farnesyl pyrophosphate binding and product release.
  Journal
Biochemistry 34:6857-62 (1995)
DOI:10.1021/bi00020a032
Reference
2  [PMID:8621375]
  Authors
Casey PJ, Seabra MC.
  Title
Protein prenyltransferases.
  Journal
J Biol Chem 271:5289-92 (1996)
DOI:10.1074/jbc.271.10.5289
Reference
3  [PMID:9657673]
  Authors
Long SB, Casey PJ, Beese LS.
  Title
Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate.
  Journal
Biochemistry 37:9612-8 (1998)
DOI:10.1021/bi980708e
  Sequence
[rno:25318 64511]
Reference
4  [PMID:11591144]
  Authors
Micali E, Chehade KA, Isaacs RJ, Andres DA, Spielmann HP.
  Title
Protein farnesyltransferase isoprenoid substrate discrimination is dependent on isoprene double bonds and branched methyl groups.
  Journal
Biochemistry 40:12254-65 (2001)
DOI:10.1021/bi011133f
Reference
5  [PMID:12374986]
  Authors
Long SB, Casey PJ, Beese LS.
  Title
Reaction path of protein farnesyltransferase at atomic resolution.
  Journal
Nature 419:645-50 (2002)
DOI:10.1038/nature00986
  Sequence
[rno:25318 64511]
Reference
6
  Authors
Gibbs, R.A.
  Title
Prenyl transfer and the enzymes of terpenoid and steroid biosynthesis.
  Journal
In: Sinnott, M. (Ed.), Comprehensive Biological Catalysis. A Mechanistic Reference, vol. 1, Academic Press, San Diego, CA, 1998, p. 31-118.
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.58
IUBMB Enzyme Nomenclature: 2.5.1.58
ExPASy - ENZYME nomenclature database: 2.5.1.58
BRENDA, the Enzyme Database: 2.5.1.58
CAS: 131384-38-8

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