KEGG   ENZYME: 2.5.1.62
Entry
EC 2.5.1.62                 Enzyme                                 
Name
chlorophyll synthase
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
chlorophyllide-a:phytyl-diphosphate phytyltransferase
Reaction(IUBMB)
chlorophyllide a + phytyl diphosphate = chlorophyll a + diphosphate [RN:R06284]
Reaction(KEGG)
R06284;
(other) R09067
Substrate
chlorophyllide a [CPD:C02139];
phytyl diphosphate [CPD:C05427]
Product
chlorophyll a [CPD:C05306];
diphosphate [CPD:C00013]
Comment
Requires Mg2+. The enzyme is modified by binding of the first substrate, phytyl diphosphate, before reaction of the modified enzyme with the second substrate, chlorophyllide a, can occur. The reaction also occurs when phytyl diphosphate is replaced by geranylgeranyl diphosphate.
History
EC 2.5.1.62 created 2003
Pathway
ec00860  Porphyrin metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K04040  chlorophyll/bacteriochlorophyll a synthase
Genes
ATHAT3G51820(G4)
ALY9312173
CRB17887345
CSAT104711728 104781015 104791427
EUSEUTSA_v10010408mg
BRP103841124 103848641
BNA106349059 106367679 106402842 106437912
BOE106311688 106315573
RSZ108813242 108834478
THJ104805975
CPAP110820892
CIT102615732
CICCICLE_v10011985mg
PVY116115169 116115195
MINC123193996
TCC18597511
GRA105780406
GHI107899551 107931248
GAB108457926
HSYR120142838 120188285
DZI111295383 111312068
EGR104422084
GMX100779167 100787459 100800348
GSJ114389040 114397459 114419087
PVU137824125
VRA106758601
VAR108320403
VUN114186304
VUM124836463
CCAJ109815417
APRC113861494
MTR25498789
TPRA123888906 123890625
CAM101495080
PSAT127127434
VVO131611926
LJA130727964
ADU107475314 107484985 110277958
AIP107625774 107625777 107639575
AHF112728023 112728025 112743675 112750534 112797059
LANG109325993 109361302
PCIN129289005
QSAO6P43_016584
FVE101311975
RCN112192971
PPER18774974
PMUM103341648
PAVI110768439
PDUL117632895
MDM103425992 103450672
MSYL126591890 126619596
PXB103930527 103940196 103965133
ZJU107430876
MNT21399438
CSAV115697046
CSV101212175
CMO103502144
BHJ120074718
MCHA111013846
CMAX111466211 111478261
CMOS111438198 111453218
CPEP111781117 111803248
RCU8283148
MEAN126665366
HBR110672569
MESC110623146
POP7466089 7487329
PEU105111157 105121921
PALZ118037508 118048500
PNZ133676908 133690181
JRE108994946 108995111
CILL122277210 122278081
CAVE132191702
QSU112005559
QLO115953950
TWL119984598
VVI100250669
VRI117920752
SLY101246752
SPEN107031547
SOT102580726
SSTN125871625
SDUL129882395
CANN107842693
LBB132630833
NTA107781977(CHLG) 107794961(CHLG)
NSY104214712
NTO104101203
NAU109235321
INI109157707 109183446
ITR115999877 116011888
SIND105174586
OEU111377928 111407076 111408022
EGT105953109
SSPL121763746 121798078
SMIL131002620
SHIS125221899
APAN127251788
HAN110865767
ECAD122590723
LSV111908627
CCAV112506489
DCR108215742
CSIN114318527
RVL131321712 131321713
AEW130773083 130782421 130794251
BVG104892512
SOE110794882
CQI110710703 110733932
ATRI130800030 130804760
MOF131167770
NNU104594932 104602567
MING122088009
TSS122670977
PSOM113313327 113313440 113323264 113338745
OSA4338498(CHLG)
OBR102706758
OGL127775174
BDI100841031
ATS109739353
TDC119276180 119340167
TAES123052740 123129081 123181728
TUA125514162
LPER127311589
LRD124706360 124706365
SBI8061338
ZMA100274372
MFLO136516454
SITA101764766
SVS117856956
PVIR120673104 120709305
PHAI112893442
PDA103709366
EGU105044579
MUS135624755
ZOF121980436 121984344 122040898 122045407
DCT110111644
PEQ110023188
AOF109843060 109850608
MSIN131253337
ACAK137942446 137965975
NCOL116255104
ATR18433480
SMOSELMODRAFT_423983 SELMODRAFT_424937
PPP112290402
CRECHLRE_06g294750v5
VCNVOLCADRAFT_80530
MNGMNEG_2517
CSLCOCSUDRAFT_27450
CVRCHLNCDRAFT_34863
APROF751_6816
OLUOSTLU_16384
OTAOT_ostta08g01100
BPGBathy04g01050
MISMICPUN_59614(CHLG)
MPPMICPUCDRAFT_33362(CHLG)
CMECYME_CMT220C
GSLGasu_27160
CCPCHC_T00008377001
PTIPHATRDRAFT_46085
FCYFRACYDRAFT_223502(ChlG)
TPSTHAPSDRAFT_4748
AAFAURANDRAFT_54854
EHXEMIHUDRAFT_421924 EMIHUDRAFT_430815
GTTGUITHDRAFT_160205(CHLG)
PAQME0F26_06725(chlG)
ALVAlvin_2645
ATEPAtep_05710
TVIThivi_2413
TMBThimo_0921
MPURMARPU_13975
TSYTHSYN_31545
TTPE6P07_13130(chlG)
THIPN838_12620(chlG)
CJAPGWK36_13335(chlG)
THIMKFB96_13290(chlG)
TBOGLT988_09010(chlG)
TLRThiosp_04087(bchG)
TFRIThiofri_01157(bchG)
TWGThiowin_00725(bchG)
HHAHhal_1600
HHKHH1059_06400
HHCM911_08250
EBSECTOBSL9_2973
PDQCL55_00013290
PANIDCO16_03320
PCOSC2747_06805(chlG)
PWUA8O14_08465
POLYPSHI2_19060
POLNPSHI8_19070
RACRA876_06150
LIML103DPR2_01006(cyoE)
LIHL63ED372_00662(cyoE)
HYRBSY239_1280(bchG)
HCZG9Q37_21665(chlG)
METPC1M51_03450
RGERGE_33410(bchG)
RBNRBXJA2T_09587
RDPRD2015_1018
ROIN4261_01115(chlG)
ATERMW290_02655(chlG)
METRBSY238_2471(bchG)
BEBAEM42_07600
RPODE0E05_11920(chlG)
AGCBSY240_3642(bchG)
RROSD4A92_02765(chlG)
ABAWD5400_05065(chlG)
PDESFE840_002455(chlG)
BRABRADO1634(bchG)
BBTBBta_6422(bchG)
BRSS23_19270(bchG)
AOLS58_59030
BROBRAD285_5766(bchG)
BRQCIT40_23895(chlG)
BGZXH91_02720
BBETF8237_24720(chlG)
BROSQUH67_09880(chlG)
BOYLQG66_15895(chlG)
RPATX73_007870(chlG)
RPBRPB_3992
RPCRPC_1302
RPDRPD_3747
RPERPE_1336
RPTRpal_1719
RPXRpdx1_3989
RHOLRBJ75_13100(chlG)
BOSBSY19_4025(bchG)
MEAMex_1p5277(bchG)
MDIMETDI5877(bchG)
MEXMext_4820
MCHMchl_5287
MPOMpop_5365
MZAB2G69_06085
MRDMrad2831_1852
METM446_3714
MORMOC_2257(chlG)
METAY590_24630
MAQUMaq22A_c01660(ubiA)
MPHYMCBMB27_01474
MEEDA075_04030
METDC0214_26370
METXA3862_21665
METSDK389_01090
METIDK427_18045
MMESMMSR116_22230(chlG)
MTEADK419_04990
MINDmvi_09130
MOGMMB17_13835(chlG)
MTADM6G65_04520(chlG)
MECLCLZ_24185(chlG)
MSLMsil_2061
BBARRHAL1_00140(bchG)
RVARvan_1002
RLACQMO75_03345(chlG)
BVRBVIR_566
BLAGBLTE_02020
MROSEHO51_17155(chlG)
MESZLNB28_08010(chlG)
CMETK6K41_01520(chlG)
AUZSa4125_27500
AUBLXB15_06260(chlG)
JIEOH818_05155(chlG)
BSBBresu_3060
BRLBZG35_15520
BREAHZ989_04535(chlG)
RUTFIU92_10020
JANJann_0165(bchG)
RDERD1_0144(bchG)
RLIRLO149_p940670(bchG)
RPONG3256_18965(chlG)
RFUROLI_002440(menA)
DSHDshi_3530(bchG)
REDroselon_01091
SUAMBOO69_19345
SUALKDD17_18430(chlG)
TOMBWR18_20055
RMMROSMUCSMR3_00877
ROKRAK1035_3747
RIDRIdsm_01783
ROMEI983_05570(chlG)
ROHFIU89_14080
THAACFI11_23665
ROTFIV09_18135
RMHLVO79_15090(chlG)
MALUKU6B_16720
PLCGRVY76_14010(chlG)
MARUFIU81_13790
RMAIMACH21_32930(bchG)
RSPRSP_0279(bchG)
RSHRsph17029_1922
RSQRsph17025_1016
RSKRSKD131_1605
CAZTLV780_04430(chlG)
RBLB6K69_03450
FYTQF092_06680(chlG)
PTPRCA23_c29750(bchG)
RSUNHU_00207(bchG)
RHMB5V46_02435
RHCRGUI_1990
LVSLOKVESSMR4R_03328(ubiA)
GEHHYN69_05445
TAWEI545_18865(chlG)
POZI0K15_16875(chlG)
NSMJO391_16385(chlG)
PBAEP8S53_17145(chlG)
RBGBG454_02955
FAQG5B39_09975(chlG)
RCPRCAP_rcc00671(bchG)
RBXI3V23_09455(chlG)
HBCAEM38_14355
NGFFRF71_09205(chlG)
NOGGKE62_08495(chlG)
NCPU0041_19885(chlG)
SPHITS85_23025
SSANNX02_18315
SAERNEF64_07805(chlG)
SGLCM1K48_13680(chlG)
SQONMP03_02255(chlG)
SRADLLW23_12275(chlG)
CIJWG74_05095
SLAAEUU25_10325(chlG)
BLASBSY18_2713(bchG)
BFWB5J99_04515
PALGHFP57_06890(chlG)
PARJJ4G78_07480(chlG)
SANDH3309_05830(chlG)
POQKZX46_18585(chlG)
PMEAKTC28_16895(chlG)
ALHG6N82_11490(chlG)
ARUEQQX03_04270(chlG)
ELQGa0102493_111827
ERKCD351_13930
ERFFIU90_13885
PNSA9D12_01340
ERYTKDC96_00955(chlG)
PORLBG023_112681
PHZCHX26_14555
POTE2E27_07280(chlG)
PORCCBR61_14980
AMVACMV_18920(bchG)
RFLRmf_21950(bchG)
SRFLHU95_14000(chlG)
RAPRHOA_2394(bchG)
NCBC0V82_18035
SKTIGS68_17210(chlG)
SMUCJL100_008825(chlG)
SROEJL101_015390(chlG)
RRURru_A0627
RRFF11_03215
RCERC1_2078(bchG)
RPMRSPPHO_00053(bchG)
ELIOKO353_02775(chlG)
THART8K17_11895(chlG)
HMOHM1_0692(bchG)
HCVFTV88_2637(bchG)
SYNslr0056(chlG)
SYZMYO_123410(chlG)
SYYSYNGTS_2317(chlG)
SYTSYNGTI_2316(chlG)
SYSSYNPCCN_2315(chlG)
SYQSYNPCCP_2315(chlG)
SYJD082_07670(chlG)
SYOC7I86_12110(chlG)
SYNHHTZ78_08300(chlG)
SYCsyc2009_d(chlG)
SYUM744_05965
SYFSynpcc7942_2084
SYDSyncc9605_0806
SYESyncc9902_1573
SYGsync_0696(chlG)
SYRSynRCC307_0577(chlG)
SYXSynWH7803_1776(chlG)
CYACYA_2138(chlG)
CYBCYB_0533(chlG)
SYNESyn6312_3275
SYNPSyn7502_01650
SYNKKR100_12045
SYNRKR49_13170
SYNDKR52_12905
SYHSyncc8109_1904(chlG)
SYNWSynWH8103_01908(chlG)
SYNCCB0101_13790(chlG)
SYNYBM449_03660
SYNZH8F24_11880(chlG)
SYNLKJJ24_08130(chlG)
SYNOLY254_05280(chlG)
DSLDacsa_1727
SYWSYNW1677(chlG)
CGCCyagr_1381
CYICBM981_1481(chlG)
PMAPro_0424(chlG)
PMMPMM0428(chlG)
PMTPMT_0272
PMNPMN2A_1759
PMIPMT9312_0427
PMBA9601_04831(chlG)
PMCP9515_04901(chlG)
PMFP9303_20661(chlG)
PMGP9301_04521(chlG)
PMHP9215_05071(chlG)
PMJP9211_04241(chlG)
PMENATL1_04811(chlG)
PRCEW14_0470
PRMEW15_0511
WNAKA717_19185(chlG)
CMPCha6605_3313
CYNCyan7425_3844
CEPCri9333_1423
TVNNIES2134_114550(chlG)
SLWBRW62_10570
TELtll1539(chlG)
THNNK55_04330(chlG)
THECFFX45_09895(chlG)
THEYJW907_02785(chlG)
TSQD3A95_12070(chlG)
AMRAM1_1019(chlG)
ACAMHRE53_03560(chlG)
TSZOOK60_13210(chlG)
LENLEP3755_21080
LETO77CONTIG1_00319
LBOLBWT_33300
LEPTJVX88_29190(chlG)
LEPVJ4558_20180(chlG)
LSCKIK02_04900(chlG)
LSKJ5X98_15775(chlG)
HHGXM38_003210(chlG)
PSEUPse7367_1220
PSERABRG53_2590(chlG)
PGXOA858_13420(chlG)
THEUHPC62_19980(chlG)
TOGHNI00_12410(chlG)
TSINOXH18_06735(chlG)
GLPGlo7428_4179
CHONNIES4102_14620
GDUP0S91_09475(chlG)
GENGM3709_3670
GEEGM3708_1057
CANCyan10605_1778
CSNCyast_0593
CYLAA637_08970(chlG)
SYPSYNPCC7002_A0548(chlG)
SYVAWQ23_02900
SYLAWQ21_02530
LEPLepto7376_1948
SYNNNIES970_10640(chlG)
PIPFEK30_06830(chlG)
MARMAE_22020(chlG)
MPKVL20_3821
MIQB5D77_20105
MVZmyaer102_54720(chlG)
HAOPCC7418_2316
ENNFRE64_01475(chlG)
CYUUCYN_08890
CYTcce_4122(chlG)
CWACwatDRAFT_6019
CYPPCC8801_1866
CYHCyan8802_1892
CYCPCC7424_1236
CYJCyan7822_3054
TERTery_0876
ARPNIES39_C02140(chlG)
PAGHNIES204_39460(chlG)
PPSUNO713_02092(CHLG)
PRUNPCC7821_04701(CHLG)
MVAGD0A34_07290(chlG)
LFSHFV01_12050(chlG)
LIXH2674_13925(chlG)
OXYHCG48_00270(chlG)
OACOscil6304_5614
ONIOsc7112_0816
MPROBJP34_26985
PHORJWS08_04265(chlG)
PYHNEA10_08275(chlG)
MICMic7113_5247
GEIGEI7407_0374
GVIglr1809(chlG)
GLJGKIL_1505(chlG)
GMLISF26_08495(chlG)
ANAall4480(chlG)
NPUNpun_R4525
NOSNos7107_0790
NOPNos7524_2510
NONNOS3756_25920
NFLCOO91_06421
NOECLI64_12480(chlG)
NSHGXM_02835
NEDHUN01_24980(chlG)
NPZACX27_13480
NLKNIES25_36280
NCWNIES2107_37180(chlG)
NCFANSO36C_08380(chlG)
AVAAva_3341
NAZAazo_0020
ANBANA_C11932(chlG)
ACYAnacy_4897
AWAAA650_17805
ANNEH233_06540(chlG)
CSGCylst_1393
RSINB6N60_00170
HBQQI031_27715(chlG)
CALOCal7507_5244
CALTCal6303_5487
CALHIJ00_11070
CALNNIES2098_53920(chlG)
CALSNIES3974_21470
RIVRiv7116_5903
MDPNIES3275_59010(chlG)
FISFIS3754_21730
NSPBMF81_03170(chlG)
NSPHBDGGKGIB_00678(menA_1)
DOUBMF77_00511
DFSHGD76_13480(chlG)
DHTNG743_07645(chlG)
DCMNIES806_25210
DOTEZY12_08635(chlG)
DOZHEP80_15585(chlG)
DOCHEQ26_01835(chlG)
CCURIAR63_11390(chlG)
CRKL3I90_01970(chlG)
AFLOHEQ12_11520(chlG)
STOQK2F26_14410(chlG)
SKVNIES73_18410
AEEIM676_01405(chlG)
RCSNIES932_22260
OCFWJM97_04245(chlG)
TOQHCG51_21055(chlG)
TTQNIES37_02790(chlG)
ALAXNIES50_17050(chlG)
SCYTSAMD_02370
SCYSNIES4073_26380
BSENDP114_00725(chlG)
BOXDP113_00715(chlG)
NCNBZZ01_22160
CTHEChro_5252
PLPPle7327_0041
SCSSta7437_2620
STANSTA3757_15840(chlG)
GLTGlitD10_1910(bchG)
GCYLQF76_13790(chlG)
CERRGRSB_1655
CEECP3F56_06870(chlG)
RRSRoseRS_3266
RCARcas_3752
CAUCaur_0138 Caur_2088
CHLChy400_0145 Chy400_2251
CAGCagg_1210 Cagg_2632
CALLOZ401_001677(chlG) OZ401_002285 OZ401_002374(chlG) OZ401_003162
VABWPS_26100(bchG)
UAMUABAM_01018
CTMCabther_A1763 Cabther_B0037
CVLJ8C06_01225(chlG) J8C06_05575 J8C06_11270(chlG)
CHLOJ8C02_08665(chlG) J8C02_11935(chlG)
GPHGEMMAAP_06375
GGRHKW67_08915(chlG)
PSPCStrain318_000120(chlG)
FLCKJS93_21160
FLVKJS94_17670
FKAKM029_20155
CTECT1270(chlG) CT1610(bchG)
CPCCpar_0576 Cpar_1271
CLZBIU88_02640 BIU88_04600
CCHCag_1105 Cag_1742
CPHCpha266_0583 Cpha266_1449
CPBCphamn1_0602 Cphamn1_1089
CLIClim_0630 Clim_1155
PVICvib_0745 Cvib_1395
PLTPlut_0911 Plut_1605
PPHPpha_0708 Ppha_1145
PAAPaes_0545 Paes_1390
PROCPtc2401_00566 Ptc2401_00764
PRSB9H02_02515 B9H02_04620
PROSCHL67_04500 CHL67_08975
PROWOO006_07960(chlG) OO006_10815(chlG)
PROIOO005_07345(chlG) OO005_09850(chlG)
CTSCtha_2034 Ctha_2606
CABYCabys_2935
 » show all
Reference
1  [PMID:12530542]
  Authors
Schmid HC, Rassadina V, Oster U, Schoch S, Rudiger W
  Title
Pre-loading of chlorophyll synthase with tetraprenyl diphosphate is an obligatory step in chlorophyll biosynthesis.
  Journal
Biol Chem 383:1769-78 (2002)
DOI:10.1515/BC.2002.198
  Sequence
Reference
2  [PMID:9092496]
  Authors
Oster U, Bauer CE, Rudiger W.
  Title
Characterization of chlorophyll a and bacteriochlorophyll a synthases by heterologous expression in Escherichia coli.
  Journal
J Biol Chem 272:9671-6 (1997)
DOI:10.1074/jbc.272.15.9671
Reference
3  [PMID:7408876]
  Authors
Rudiger W, Benz J, Guthoff C.
  Title
Detection and partial characterization of activity of chlorophyll synthetase in etioplast membranes.
  Journal
Eur J Biochem 109:193-200 (1980)
DOI:10.1111/j.1432-1033.1980.tb04784.x
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.62
IUBMB Enzyme Nomenclature: 2.5.1.62
ExPASy - ENZYME nomenclature database: 2.5.1.62
BRENDA, the Enzyme Database: 2.5.1.62
CAS: 9077-08-1

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