KEGG   ENZYME: 2.5.1.89
Entry
EC 2.5.1.89                 Enzyme                                 
Name
tritrans,polycis-undecaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
geranylgeranyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 7 isopentenyl units)
Reaction(IUBMB)
geranylgeranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + tritrans,heptacis-undecaprenyl diphosphate [RN:R09730]
Reaction(KEGG)
R09730
Substrate
geranylgeranyl diphosphate [CPD:C00353];
isopentenyl diphosphate [CPD:C00129]
Product
diphosphate [CPD:C00013];
tritrans,heptacis-undecaprenyl diphosphate [CPD:C19852]
Comment
This enzyme is involved in the biosynthesis of the glycosyl carrier lipid in some archaebacteria. Unlike EC 2.5.1.31, its counterpart in most bacteria, it prefers geranylgeranyl diphosphate to farnesyl diphosphate as the allylic substrate, resulting in production of a tritrans,polycis variant of undecaprenyl diphosphate [1].
History
EC 2.5.1.89 created 2010, modified 2011
Pathway
ec00900  Terpenoid backbone biosynthesis
Orthology
K15888  tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific]
Genes
MARW: MNSC_05880(uppS)
MJA: MJ_1372
MFE: Mefer_0013
MVU: Metvu_0730
MFS: MFS40622_0557
MIF: Metin_0747
MJH: JH146_0409
MESG: MLAUSG7_0959(uppS)
MESA: MLASG1_0294(uppS)
MIG: Metig_0007
MMP: MMP1345
MMQ: MmarC5_0233
MMX: MmarC6_1328
MMZ: MmarC7_0590
MMD: GYY_07550
MMAK: MMKA1_15680(uppS)
MMAO: MMOS7_14490(uppS)
MMAD: MMJJ_14940
MAE: Maeo_1136
MVN: Mevan_0656
MVO: Mvol_0149
MOK: Metok_0698
METF: CFE53_05195(uppS)
MTH: MTH_232
MMG: MTBMA_c06810(uppS)
MWO: MWSIV6_0644(uppS)
MTEE: MTTB_08750
METC: MTCT_0194
METE: tca_00212
METZ: METMT2_0676
METK: FVF72_01145(uppS)
MTHM: FZP57_03065(uppS)
METJ: FZP68_08100(uppS)
MST: Msp_1182(uppS)
METB: AW729_09855
MEIS: PXD04_01710(uppS)
MRU: mru_1005(uppS)
MSI: Msm_0096
MEB: Abm4_0676(uppS)
MMIL: sm9_0974(uppS)
MEYE: TL18_05495
MOL: YLM1_0546
MARO: MarbSA_04520
METV: K4897_00900(uppS)
MEL: Metbo_2128
MEW: MSWAN_0483
METH: MBMB1_0608(uppS)
MFC: BRM9_1627(uppS)
MFI: DSM1535_2322(uppS)
MCUB: MCBB_0494(uppS)
MSUB: BK009_01135
METN: BK008_08825
METT: CIT01_09500(uppS)
METO: CIT02_03890(uppS)
MEME: HYG87_09880(uppS)
MFEG: GCM10025860_16180 GCM10025860_19110
MEER: NKF70_09335(uppS)
MRID: FGU46_02375(uppS)
MFV: Mfer_0595
MKA: MK0767(uppS)
AFU: AF_1219
AFG: AFULGI_00013180
APO: Arcpr_0491
AVE: Arcve_0125
AST: Asulf_00506
FPL: Ferp_1985
GAC: GACE_0233
GAH: GAH_00064
PFU: PF1599
PFI: PFC_07225
PHO: PH1590(PH1590)
PAB: PAB0394(hypoth)
PYN: PNA2_0175
PYA: PYCH_04910
PYS: Py04_1477
PYC: TQ32_08915
TKO: TK1173
TON: TON_0373
TGA: TGAM_0719(uppS)
TSI: TSIB_1513
TBA: TERMP_00685
THE: GQS_03365
THA: TAM4_934
THM: CL1_0304
TLT: OCC_03007
THS: TES1_0768
TNU: BD01_0338
TEU: TEU_07395
TGY: X802_06815
THV: ADU37_CDS16370
TCH: CHITON_1826
TPEP: A0127_09070
TPIE: A7C91_07885
TGG: A3K92_05410
TCE: A3L02_09525
TBS: A3L01_02570
THH: CDI07_02520(uppS)
TSL: A3L11_06495
TTD: A3L14_04035
TPRF: A3L09_07815
TRL: A3L10_04015
TPAF: A3L08_05560
THY: A3L12_06160
TIC: FH039_04835(uppS)
TCQ: TIRI35C_0737(uppS)
THEM: FPV09_04325(uppS)
THEI: K1720_00380(uppS)
TAGG: NF865_05155(uppS)
PPAC: PAP_02925
MBA: Mbar_A0263
MBY: MSBRM_2692
MBW: MSBRW_0733
MBAR: MSBR2_2648
MBAK: MSBR3_2777
MAC: MA_3723(uppS)
MMA: MM_0618
MMAZ: MmTuc01_0629
MMJ: MSMAS_0691
MMAC: MSMAC_0692
MVC: MSVAZ_0672
MEK: MSKOL_0650
MLS: MSLAZ_2243
METM: MSMTP_0756
MEF: MSWH1_0870
MEQ: MSWHS_0929
MSJ: MSSAC_3535
MSZ: MSSIH_3076
MSW: MSSIT_3134
MTHR: MSTHT_2395
MTHE: MSTHC_0884
MHOR: MSHOH_0806
MFZ: AOB57_003440(uppS)
MHAB: RSJ42_12145(uppS)
METW: AAY43_06165
MBU: Mbur_0041
MMET: MCMEM_0626
MELO: J7W08_01190(uppS)
MMH: Mmah_1238
MHAZ: BHR79_07355
MPOT: BKM01_03600
MEV: Metev_0825 Metev_2270
MZH: Mzhil_1185
MPY: Mpsy_1109
MZI: HWN40_03045(uppS)
MMAV: RE476_07200(uppS)
MSEB: RE474_03465(uppS)
MHZ: Metho_1987
MEHF: MmiHf6_01370(uppS_1)
MEES: MmiEs2_08520(uppS_1)
MTP: Mthe_0589
MCJ: MCON_0296(uppS)
MHI: Mhar_2350
MHU: Mhun_0785
MRTJ: KHC33_09690(uppS)
MLA: Mlab_0118
MEM: Memar_1788
MBG: BN140_0601(uppS)
MEMA: MMAB1_0780(uppS)
MCHK: MchiMG62_20500
MSUM: OH143_03155(uppS)
MRC: R6Y96_08595(uppS)
MPI: Mpet_0736
MEND: L6E24_04925(uppS)
MEFW: F1737_07380(uppS)
MAQE: RJ40_09710(uppS)
MFK: E2N92_09930(uppS)
MOU: OU421_12925(uppS)
MESB: L1S32_04680(uppS)
MANQ: L1994_07620(uppS)
MBN: Mboo_2063
MFO: Metfor_0792
MPL: Mpal_0107
MPD: MCP_1817(uppS)
MEZ: Mtc_1306(uppS-2)
RCI: RRC441(uppS-2)
HAL: VNG_1779C
HSL: OE_3503F(uppS1)
HANR: LJ422_07170(uppS)
HDL: HALDL1_13885
HHB: Hhub_3075(uppS1)
HAGS: JT689_08515(uppS)
HABO: JRZ79_06925(uppS)
HNO: LT974_12305(uppS)
HLU: LT972_02610(uppS)
HANX: ABSL23_15225(uppS)
HALH: HTSR_0407
HHSR: HSR6_0392(uppS2)
HSU: HLASF_1850(uppS1)
HSF: HLASA_1836(uppS1)
HAHS: HSRCO_2460(uppS)
SALR: FQU85_06950(uppS)
HALR: EFA46_001210(uppS)
HJE: HacjB3_06135
HDO: MUK72_12540(uppS)
HALX: M0R89_02070(uppS)
HAXZ: M0R88_02045(uppS)
HAYC: NGM10_12020(uppS)
HAXY: NGM07_07480(uppS)
SALI: L593_09975
SAIM: K0C01_03025(uppS)
HARA: AArcS_0442(uppS)
HMA: rrnAC1716(uppS)
HHI: HAH_2250(uppS1)
HHN: HISP_11460
HAB: SG26_03830
HTA: BVU17_10985
HALJ: G9465_16135(uppS)
HSIN: KDQ40_02130(uppS)
NPH: NP_4550A(uppS1)
NMO: Nmlp_2341(uppS1)
NHO: HWV23_03155(uppS)
NSAL: HWV07_17065(uppS)
HUT: Huta_2829
HTI: HTIA_2734
HALA: Hrd1104_05035(uppS)
HASV: SVXHr_1747(uppS2)
HABN: HBNXHr_1734(uppS2)
HMU: Hmuk_1548
HALZ: E5139_10865(uppS)
HALL: LC1Hm_0765(uppS)
HAZP: GBQ70_10860(uppS)
HALI: BV210_13510
HSN: DV733_13415(uppS)
HDS: HSR122_1525(uppS)
HRR: HZS55_13135(uppS)
HPEL: HZS54_17080(uppS)
HLT: I7X12_00640(uppS)
HARC: HARCEL1_06025(uppS)
SSAI: N0B31_12275(uppS)
HAAD: MW046_02285(uppS)
HWA: HQ_3332A(uppS2)
HWC: Hqrw_3861(uppS2)
HVO: HVO_2315(uppS1)
HALE: G3A49_14790(uppS)
HLN: SVXHx_2297(uppS2)
HME: HFX_2325(uppS)
HGI: ABY42_11520
HLS: KU306_01670(uppS)
HBO: Hbor_07310
HAQ: DU484_16985(uppS)
HAJ: DU500_00030(uppS)
HAER: DU502_15195(uppS)
HRA: EI982_15070(uppS)
HLM: DV707_01865(uppS)
HALM: FCF25_03620(uppS)
HLA: Hlac_2063
HALP: DOS48_09765(uppS)
HALB: EKH57_14675(uppS)
HEZZ: EO776_10170(uppS)
HALQ: Hrr1229_012105(uppS)
HSS: J7656_05270(uppS)
HSAI: HPS36_03735(uppS) HPS36_10485(uppS)
HAZZ: KI388_09475(uppS)
SRUB: C2R22_16735(uppS)
HAE: halTADL_0759 halTADL_1546
HALN: B4589_014625(uppS)
HALG: HUG10_08895(uppS)
HALU: HUG12_07165(uppS)
HMP: K6T50_06435(uppS)
HRE: K6T36_06210(uppS)
HRM: K6T25_09575(uppS)
HACB: Hbl1158_13150(uppS)
HDF: AArcSl_1515
HAH: Halar_2577
HTU: Htur_3250
HSAL: JMJ58_12205(uppS)
HAKZ: J0X25_04460(uppS)
NMG: Nmag_1224(uppS1)
HXA: Halxa_2121
NAT: NJ7G_2495
NPE: Natpe_0579
NVR: FEJ81_03230(uppS)
NPL: FGF80_07730(uppS)
NAY: HYG81_07640(uppS)
HALY: HYG82_10385(uppS)
HJT: DVR14_12120(uppS)
HLO: J0X27_13255(uppS)
NGE: Natgr_3192
HLC: CHINAEXTREME08125
HRU: Halru_2195
SAWL: NGM29_01480(uppS)
HALV: NGM15_11090(uppS)
NOU: Natoc_2038
HLR: HALLA_17025
NAJ: B1756_11845
NAG: AArcMg_3021
NAN: AArc1_0682
NARA: QQ977_04530(uppS)
NBG: DV706_03890(uppS)
NAS: GCU68_09075(uppS)
HDA: BB347_00350
MEAM: MU439_01005(uppS)
MEAE: QEN48_01600(uppS)
TAC: Ta0546
TVO: TVG0591988(TVG0591988)
OMR: OXIME_000394(uppS)
PTO: PTO1378
FAC: FACI_IFERC01G1594
FAI: FAD_0573
CDIV: CPM_0361
TAR: TALC_00206
MAX: MMALV_01930
MER: MMINT_01960
MEAR: Mpt1_c12690(uppS)
MEUZ: KRP56_01080(uppS)
MARC: AR505_1636
ABI: Aboo_0417
ACF: AciM339_0631
ACJ: ACAM_0874(uppS)
SMR: Smar_1245
SHC: Shell_1211
IHO: Igni_0586
IIS: EYM_01550
IPC: IPA_03285
DKA: DKAM_0927
DFD: Desfe_1048
DMU: Desmu_0134
TAG: Tagg_0145
TCS: IMZ38_06800(uppS)
IAG: Igag_0013
THG: TCELL_0064
HBU: Hbut_1087
PFM: Pyrfu_1960
PDL: Pyrde_0981
PABI: PABY_07930(uppS)
PARE: PYJP_13650(uppS)
STO: STK_01890(uppS)
SOH: D1869_00415(uppS)
SJV: SJAV_11540(uppS)
SSO: SSO0163
SOL: Ssol_1140
SSOA: SULA_1176(uppS)
SSOL: SULB_1177(uppS)
SSOF: SULC_1175(uppS)
SSHI: J5U23_00102
SCAS: SACC_00750
SIS: LS215_2142
SIA: M1425_1977
SIM: M1627_2055
SID: M164_1983
SIY: YG5714_2100
SIN: YN1551_0818
SII: LD85_2238
SIH: SiH_1921
SIR: SiRe_1848
SIC: SiL_1830
SULA: BFU36_05125
SULE: GFS03_10830(uppS)
SAI: Saci_0757
SACN: SacN8_03680
SACR: SacRon12I_03665
SACS: SUSAZ_03395
SULL: EWF20_01855(uppS)
MSE: Msed_0171
MEMJ: MJ1HA_0250
MCN: Mcup_1902
MHK: DFR87_05955(uppS)
MPRU: DFR88_05785(uppS)
MTEN: GWK48_06235(uppS)
MJN: MjAS7_0754
AHO: Ahos_0890
AMAN: B6F84_08300
ABRI: DFR85_06545(uppS)
ASUL: DFR86_07315(uppS)
AAMB: D1866_12345(uppS)
ACIH: HS5_22650
SACD: HS1genome_0851
SAZO: D1868_01560(uppS)
CSTY: KN1_18100
STEP: IC006_1909
SMET: RQ359_002314(uppS)
SAHS: HS7_19990
PAI: PAE2942
PIS: Pisl_0348
PCL: Pcal_1157
PAS: Pars_1319
PYR: P186_1582
POG: Pogu_0896
TNE: Tneu_1777
PYW: PYWP30_01898
CMA: Cmaq_0786
TTN: TTX_0656(uppS)
TUZ: TUZN_0298
VDI: Vdis_0938
VMO: VMUT_1786
VSO: Vsou_11070
TPE: Tpen_0762
THB: N186_05330
TCB: TCARB_0131
THF: MA03_05695
THEL: IG193_03675(uppS)
ASC: ASAC_1265
ACIA: SE86_07500
CLG: Calag_0868
FFO: FFONT_1224
KCR: Kcr_0245
MVJ: ACO0C9_02450(uppS)
NMR: Nmar_1416
NIR: NSED_07775
NKR: NKOR_07805
NID: NPIRD3C_2077(uppS)
NIN: NADRNF5_0463(uppS)
NIW: Nisw_06890(uppS)
NCL: C5F47_07515(uppS)
NOX: C5F49_07395(uppS)
NUE: C5F50_10710(uppS)
NIP: NsoK4_01175(uppS)
NZT: NZOSNM25_000359
NCT: NMSP_0329(uppS)
NIC: DSQ20_08340(uppS)
NGA: Ngar_c35510(uppS)
NVN: NVIE_018850
NEV: NTE_00400
TAA: NMY3_03347
NFN: NFRAN_0752(uppS)
NCV: NCAV_0511(uppS)
NDV: NDEV_1710(uppS)
CSY: CENSYa_1470
CSU: CSUB_C0295
NBV: T478_0360(uppS)
TAH: SU86_008615
NIU: DSQ19_07980(uppS)
CCAI: NAS2_0133
BARC: AOA65_0926(uppS)
BARB: AOA66_0322(uppS)
NAA: Nps_02790
MARH: Mia14_0585
FLT: Sv326_1286
MIY: Micr_00783(uppS_2)
WAR: HYS32_03705(uppS)
LOKI: Lokiarch_02280(uppS_1) Lokiarch_37300(uppS_2)
LOB: NEF87_003594
PSYT: DSAG12_01206(uppS)
AGW: QT03_C0001G0549 QT03_C0001G0683(uppS) QT03_C0001G0830
ARG: QT11_C0001G0984
 » show all
Reference
1  [PMID:11114943]
  Authors
Hemmi H, Yamashita S, Shimoyama T, Nakayama T, Nishino T
  Title
Cloning, expression, and characterization of cis-polyprenyl diphosphate synthase from the thermoacidophilic archaeon Sulfolobus acidocaldarius.
  Journal
J Bacteriol 183:401-4 (2001)
DOI:10.1128/JB.183.1.401-404.2001
  Sequence
[sai:Saci_0757]
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.89
IUBMB Enzyme Nomenclature: 2.5.1.89
ExPASy - ENZYME nomenclature database: 2.5.1.89
BRENDA, the Enzyme Database: 2.5.1.89

  All links  
Gene (4249)   
   MGENES (3355)   
   RefGene (894)   
Protein sequence (2886)   
   UniProt (2865)   
   SWISS-PROT (20)   
   RefSeq(pep) (1)   
DNA sequence (175)   
   RefSeq(nuc) (2)   
   GenBank (88)   
   EMBL (85)   
Protein domain (3)   
   InterPro (3)   
All databases (7313)   

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