KEGG   ENZYME: 2.6.1.104Help
Entry
EC 2.6.1.104                Enzyme                                 

Name
3-dehydro-glucose-6-phosphate---glutamate transaminase;
3-oxo-glucose-6-phosphate:glutamate aminotransferase;
ntdA (gene name)
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
kanosamine 6-phosphate:2-oxoglutarate aminotransferase
Reaction(IUBMB)
kanosamine 6-phosphate + 2-oxoglutarate = 3-dehydro-D-glucose 6-phosphate + L-glutamate [RN:R10698]
Reaction(KEGG)
Substrate
kanosamine 6-phosphate [CPD:C12213];
2-oxoglutarate [CPD:C00026]
Product
3-dehydro-D-glucose 6-phosphate [CPD:C20668];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein. The enzyme, found in the bacterium Bacillus subtilis, is involved in a kanosamine biosynthesis pathway.
History
EC 2.6.1.104 created 2014
Pathway
ec00998  Biosynthesis of secondary metabolites - other antibiotics
ec01100  Metabolic pathways
Orthology
K18653  3-dehydro-glucose-6-phosphate---glutamate transaminase
Genes
ECV: APECO1_O1CoBM86
YEL: LC20_02629
YSI: BF17_06545
EPY: EpC_29560
EPR: EPYR_03197(yhjL)
EAM: EAMY_0627(yhjL)
EAY: EAM_2803(ntdA)
ERJ: EJP617_17800
XBV: XBW1_3412(ntdA)
BSU: BSU10550(ntdA)
BSR: I33_1189
BSL: A7A1_3679
BSH: BSU6051_10550(ntdA)
BSUT: BSUB_01152(ntdA)
BSUL: BSUA_01152(ntdA)
BSUS: Q433_05970
BSS: BSUW23_05350(ntdA)
BST: GYO_1359
BSO: BSNT_07499(yhjL)
BSQ: B657_10550(ntdA)
BSX: C663_1079(ntdA)
BLI: BL03980(ntdA)
BLD: BLi03946(ntdA)
BLH: BaLi_c39610(ntdA)
BCX: BCA_3326
BCF: bcf_16050
BTL: BALH_2925
BTW: BF38_4422
BPU: BPUM_0280
BPUM: BW16_01755
BPUS: UP12_01730
BACW: QR42_01710
BACY: QF06_04210
BACL: BS34A_11690(ntdA)
BALM: BsLM_1098
MAB: MAB_2610
MABB: MASS_2568
 » show all
Taxonomy
Reference
1  [PMID:19342798]
  Authors
van Straaten KE, Langill DM, Palmer DR, Sanders DA
  Title
Purification, crystallization and preliminary X-ray analysis of NtdA, a putative  pyridoxal phosphate-dependent aminotransferase from Bacillus subtilis.
  Journal
Acta Crystallogr Sect F Struct Biol Cryst Commun 65:426-9 (2009)
DOI:10.1107/S1744309109009038
Reference
2  [PMID:23586652]
  Authors
Vetter ND, Langill DM, Anjum S, Boisvert-Martel J, Jagdhane RC, Omene E, Zheng H, van Straaten KE, Asiamah I, Krol ES, Sanders DA, Palmer DR
  Title
A previously unrecognized kanosamine biosynthesis pathway in Bacillus subtilis.
  Journal
J Am Chem Soc 135:5970-3 (2013)
DOI:10.1021/ja4010255
  Sequence
[bsu:BSU10550]
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.104
IUBMB Enzyme Nomenclature: 2.6.1.104
ExPASy - ENZYME nomenclature database: 2.6.1.104
BRENDA, the Enzyme Database: 2.6.1.104

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