KEGG   ENZYME: 2.6.1.107Help
Entry
EC 2.6.1.107                Enzyme                                 

Name
beta-methylphenylalanine transaminase;
TyrB
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
(2S,3S)-3-methylphenylalanine:2-oxoglutarate aminotransferase
Reaction(IUBMB)
(2S,3S)-3-methylphenylalanine + 2-oxoglutarate = (3S)-2-oxo-3-phenylbutanoate + L-glutamate [RN:R10845]
Reaction(KEGG)
Substrate
(2S,3S)-3-methylphenylalanine [CPD:C20895];
2-oxoglutarate [CPD:C00026]
Product
(3S)-2-oxo-3-phenylbutanoate [CPD:C20646];
L-glutamate [CPD:C00025]
Comment
Requires pyridoxal phosphate. Isolated from the bacterium Streptomyces hygroscopicus NRRL3085. It is involved in the biosynthesis of the glycopeptide antibiotic mannopeptimycin.
History
EC 2.6.1.107 created 2014
Reference
1  [PMID:19731276]
  Authors
Huang YT, Lyu SY, Chuang PH, Hsu NS, Li YS, Chan HC, Huang CJ, Liu YC, Wu CJ, Yang WB, Li TL
  Title
In vitro characterization of enzymes involved in the synthesis of nonproteinogenic residue (2S,3S)-beta-methylphenylalanine in glycopeptide antibiotic mannopeptimycin.
  Journal
Chembiochem 10:2480-7 (2009)
DOI:10.1002/cbic.200900351
  Sequence
[eco:b4054]
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.107
IUBMB Enzyme Nomenclature: 2.6.1.107
ExPASy - ENZYME nomenclature database: 2.6.1.107
BRENDA, the Enzyme Database: 2.6.1.107

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