| Entry |
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| Name |
diiodotyrosine transaminase;
diiodotyrosine aminotransferase;
halogenated tyrosine aminotransferase;
halogenated tyrosine transaminase
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| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
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| Sysname |
3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase
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| Reaction(IUBMB) |
3,5-diiodo-L-tyrosine + 2-oxoglutarate = 4-hydroxy-3,5-diiodophenylpyruvate + L-glutamate [RN: R03207]
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| Reaction(KEGG) |
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| Substrate |
3,5-diiodo-L-tyrosine [CPD: C01060];
2-oxoglutarate [CPD: C00026]
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| Product |
4-hydroxy-3,5-diiodophenylpyruvate;
L-glutamate [CPD: C00025]
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| Comment |
A pyridoxal-phosphate protein. Also acts on 3,5-dichloro-, 3,5-dibromo- and 3-iodo-L-tyrosine, thyroxine and triiodothyronine.
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| History |
EC 2.6.1.24 created 1972 (EC 2.6.1.25 created 1972, incorporated 1972)
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| Reference |
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| Authors |
Nakano M. |
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| Title |
Purification and properties of halogenated tyrosine and thyroid hormone transaminase from rat kidney mitochondria. |
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| Journal |
J Biol Chem 242:73-81 (1967) |
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| Reference |
|
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| Authors |
NAKANO M, DANOWSKI TS. |
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| Title |
THYROID-HORMONE TRANSAMINASE AND OXIDASE IN RAT-KIDNEY MITOCHONDRIA. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.6.1.24 |
| ExPASy - ENZYME nomenclature database: | 2.6.1.24 |
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