KEGG   ENZYME: 2.6.1.27
Entry
EC 2.6.1.27                 Enzyme                                 
Name
tryptophan transaminase;
L-phenylalanine-2-oxoglutarate aminotransferase;
tryptophan aminotransferase;
5-hydroxytryptophan-ketoglutaric transaminase;
hydroxytryptophan aminotransferase;
L-tryptophan aminotransferase;
L-tryptophan transaminase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
Sysname
L-tryptophan:2-oxoglutarate aminotransferase
Reaction(IUBMB)
L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate [RN:R00684]
Reaction(KEGG)
R00684;
(other) R02700
Substrate
L-tryptophan [CPD:C00078];
2-oxoglutarate [CPD:C00026]
Product
(indol-3-yl)pyruvate [CPD:C00331];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein. Also acts on 5-hydroxytryptophan and, to a lesser extent, on the phenyl amino acids.
History
EC 2.6.1.27 created 1972
Pathway
ec00380  Tryptophan metabolism
ec01100  Metabolic pathways
Orthology
K00838  aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
K14265  tryptophan aminotransferase
Genes
DNM101421111
QSU112001990 112026216
MNGMNEG_3800
SCEYGL202W(ARO8)
SEUBDI49_1777
SPAOSPAR_G00550
AGOAGOS_AFR548C AGOS_AGR167W
ERCEcym_7228
KLAKLLA0_A04906g KLLA0_F10021g
KMXKLMA_20259(ARO8) KLMA_50151(ARO8)
LTHKLTH0E07678g KLTH0G02002g
VPOKpol_278p2
ZROZYRO0C06028g
CGRCAGL0G01254g
NCSNCAS_0E00670(NCAS0E00670)
NDINDAI_0I02830(NDAI0I02830)
TPFTPHA_0D03370(TPHA0D03370)
TGBHG536_0D05130
TDLTDEL_0D05790(TDEL0D05790)
KAFKAFR_0D01420(KAFR0D01420)
KNGKNAG_0B00660(KNAG0B00660)
ZMKHG535_0B02410 HG535_0F03900
PPAPAS_chr1-4_0608
DHADEHA2A06886g
PICPICST_66767(ARO8)
PGUPGUG_02078 PGUG_04621
SPAASPAPADRAFT_60926
LELLELG_01198
CALCAALFM_C200340CA(ARO8)
CTPCTRG_01079
COTCORT_0A12760
CDUCD36_15310
CTENCANTEDRAFT_94668
YLIYALI0E20977g
CLUCLUG_00783
CLUSA9F13_10g00462
CAURCJI97_001662
SLBAWJ20_1088(ARO8)
PKZC5L36_0A12110 C5L36_0E01100
BNNFOA43_000076 FOA43_002087
BBRXBRETT_001037 BRETT_003919
OPAHPODL_01516 HPODL_01574
SLUDSCDLUD_001488 SCDLUD_002357
NCRNCU09116
SMPSMAC_04612
PANPODANSg5646
TTTTHITE_2121569
MTMMYCTH_2294749
CTHRCTHT_0057710
MGRMGG_09919 MGG_14221
PPEIPpBr36_07692 PpBr36_09659
TMNUCRPA7_6517
SSCKSPSK_08879
FGRFGSG_01285
FPUFPSE_11596
FVRFVEG_01416 FVEG_03489
FOXFOXG_00100 FOXG_05640 FOXG_09911
NHENECHADRAFT_50127 NECHADRAFT_51829 NECHADRAFT_74483 NECHADRAFT_94787
TRETRIREDRAFT_105978 TRIREDRAFT_57322
TRRM419DRAFT_7300 M419DRAFT_99227
MAWMAC_07121
MAJMAA_00168
CMTCCM_06988
PLJVFPFJ_03307
VALVDBG_04940
VDAVDAG_04481
CFJCFIO01_05667 CFIO01_06036 CFIO01_12021
CLUPCLUP02_05332 CLUP02_15557
CHIGCH63R_00489
SAPOSAPIO_CDS0338 SAPIO_CDS3624
ELAUCREL1_11541
PFYPFICI_00876 PFICI_05473 PFICI_07657 PFICI_08638
SSLSS1G_10035
BFUBCIN_07g04780(Bcaro8)
MBEMBM_09282
PSCOLY89DRAFT_633729
GLZGLAREA_00731
ANIAN4156.2 AN6338.2 AN8519.2
AFMAFUA_2G13630
ACTACLA_073980
NFINFIA_088830
AORAO090020000444 AO090026000245
ANGANI_1_2088024(An02g00030) ANI_1_766024(An02g05540)
AFVAFLA_006053 AFLA_006709 AFLA_010210
ALUCAKAW2_21160S(ARO8_1) AKAW2_21604S
ACHEACHE_50803A(ARO8_2)
APUUAPUU_51301A(ARO8_2) APUU_80012S
PCSPc12g11860
PDPPDIP_79130
TMFPMAA_035050
TRGTRUGW13939_05336 TRUGW13939_11796
CIMCIMG_04628
CPWCPC735_071790
UREUREG_01826
PBLPAAG_05743
PBNPADG_07646
ABEARB_01306
TVETRV_00012
AJEHCAG_04617
BGHBDBG_04597 BDBG_16211
PNOSNOG_04259
PTEPTT_08476
BZECOCCADRAFT_104299
BSCCOCSADRAFT_92370
BORCOCMIDRAFT_487
AALTCC77DRAFT_1049425
ZTRMYCGRDRAFT_100367
PFJMYCFIDRAFT_57678
FFUCLAFUR5_06006 CLAFUR5_08181
BCOMBAUCODRAFT_578314
NPAUCRNP2_4527 UCRNP2_8015
TMLGSTUM_00008805001
SPOSPAC56E4.03 SPBC1773.13 SPCC569.07
CNECNB03000 CNB03180 CNF01590 CNF04620
CNBCNBB2510 CNBB2710 CNBF0280 CNBF3120
CNGCNAG_03808 CNAG_03828 CNAG_05820 CNAG_06555
CGICGB_A3370W CGB_F4480C
TMSTREMEDRAFT_34172 TREMEDRAFT_68672 TREMEDRAFT_71644
TASAA1Q1_00184 A1Q1_05326 A1Q1_05529 A1Q1_06907 A1Q1_07720
PPLPOSPLDRAFT_89909
TVSTRAVEDRAFT_133162 TRAVEDRAFT_38052 TRAVEDRAFT_56842 TRAVEDRAFT_72661
DSQDICSQDRAFT_133615 DICSQDRAFT_135879 DICSQDRAFT_178445 DICSQDRAFT_181832
PCOPHACADRAFT_207395 PHACADRAFT_250454 PHACADRAFT_253130 PHACADRAFT_28172
SHSSTEHIDRAFT_120086 STEHIDRAFT_137204 STEHIDRAFT_152122 STEHIDRAFT_170511 STEHIDRAFT_58581 STEHIDRAFT_60514 STEHIDRAFT_80491
HIRHETIRDRAFT_380789 HETIRDRAFT_458781
PSQPUNSTDRAFT_104522 PUNSTDRAFT_125467 PUNSTDRAFT_52167
ADLAURDEDRAFT_112435 AURDEDRAFT_114554 AURDEDRAFT_116968 AURDEDRAFT_130695 AURDEDRAFT_147363 AURDEDRAFT_54486 AURDEDRAFT_75410 AURDEDRAFT_93142
FMEFOMMEDRAFT_165688 FOMMEDRAFT_169725 FOMMEDRAFT_25327 FOMMEDRAFT_61360
GTRGLOTRDRAFT_131793 GLOTRDRAFT_71756 GLOTRDRAFT_75354 GLOTRDRAFT_98301
LBCLACBIDRAFT_191053 LACBIDRAFT_311755
CCICC1G_07874 CC1G_11694 CC1G_14996 CC1G_15151
ABPAGABI1DRAFT113513(AGABI1DRAFT_113513) AGABI1DRAFT75541(AGABI1DRAFT_75541) AGABI1DRAFT75553(AGABI1DRAFT_75553)
ABVAGABI2DRAFT191531(AGABI2DRAFT_191531) AGABI2DRAFT191838(AGABI2DRAFT_191838) AGABI2DRAFT201971(AGABI2DRAFT_201971)
PCUBJR316_0005155 JR316_0005698
MPRMPER_11136
MRRMoror_12963 Moror_14804 Moror_17465 Moror_3409 Moror_9956
MOREE1B28_009660 E1B28_010878 E1B28_010888 E1B28_013419
SCMSCHCO_02482695(SCHCODRAFT_02482695) SCHCO_02616666(SCHCODRAFT_02616666) SCHCO_02623001(SCHCODRAFT_02623001) SCHCO_02626718(SCHCODRAFT_02626718) SCHCO_02681983(SCHCODRAFT_02681983)
CPUTCONPUDRAFT_100638 CONPUDRAFT_140570 CONPUDRAFT_142726 CONPUDRAFT_151445
SLASERLADRAFT_356993(amt1) SERLADRAFT_414134 SERLADRAFT_467467 SERLADRAFT_475830
WSEWALSEDRAFT_70869
WICJ056_001316
UMAUMAG_01804 UMAG_03538
PFPPFL1_00079 PFL1_02593
MGLMGL_2601
MRTMRET_0487
MSYMMSY001_0235
PGRPGTG_01133
MLRMELLADRAFT_103845 MELLADRAFT_115660
SMINv1.2.016220.t1(symbB.v1.2.016220.t1)
 » show all
Reference
1  [PMID:5722279]
  Authors
George H, Gabay S.
  Title
Brain aromatic aminotransferase. I. Purification and some properties of pig brain L-phenylalanine-2-oxoglutarate aminotransferase.
  Journal
Biochim Biophys Acta 167:555-66 (1968)
DOI:10.1016/0005-2744(68)90045-4
Reference
2  [PMID:5697992]
  Authors
O'Neil SR, DeMoss RD.
  Title
Tryptophan transaminase from Clostridium sporogenes.
  Journal
Arch Biochem Biophys 127:361-9 (1968)
DOI:10.1016/0003-9861(68)90237-3
Reference
3  [PMID:14285270]
  Authors
TANGEN O, FONNUM F, HAAVALDSEN R.
  Title
SEPARATION AND PURIFICATION OF AROMATIC AMINO ACID TRANSAMINASES FROM RAT BRAIN.
  Journal
Biochim Biophys Acta 96:82-90 (1965)
DOI:10.1016/0005-2787(65)90612-X
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.27
IUBMB Enzyme Nomenclature: 2.6.1.27
ExPASy - ENZYME nomenclature database: 2.6.1.27
BRENDA, the Enzyme Database: 2.6.1.27
CAS: 9022-98-4

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