| Entry |
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| Name |
L-lysine 6-transaminase;
lysine 6-aminotransferase;
lysine epsilon-aminotransferase;
lysine epsilon-transaminase;
lysine:2-ketoglutarate 6-aminotransferase;
L-lysine-alpha-ketoglutarate aminotransferase;
L-lysine-alpha-ketoglutarate 6-aminotransferase
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| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
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| Sysname |
L-lysine:2-oxoglutarate 6-aminotransferase
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| Reaction(IUBMB) |
L-lysine + 2-oxoglutarate = (S)-2-amino-6-oxohexanoate + L-glutamate [RN: R00457]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
(S)-2-amino-6-oxohexanoate [CPD: C04076];
L-glutamate [CPD: C00025]
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| Comment |
A pyridoxal-phosphate protein. The product (L-allysine) is converted into the intramolecularly dehydrated form, (S)-2,3,4,5-tetrahydropyridine-2-carboxylate.
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| History |
EC 2.6.1.36 created 1972, modified 2011
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| Orthology |
| K03918 | L-lysine 6-transaminase |
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| Genes |
» show all
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| Reference |
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| Authors |
Soda K, Misono H, Yamamoto T. |
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| Title |
L-Lysine:alpha-ketoglutarate aminotransferase. I. Identification of a product, delta-1-piperideine-6-carboxylic acid. |
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| Journal |
Biochemistry 7:4102-9 (1968) |
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| Reference |
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| Authors |
Soda K, Misono H. |
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| Title |
L-Lysine:alpha-ketoglutarate aminotransferase. II. Purification, crystallization, and properties. |
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| Journal |
Biochemistry 7:4110-9 (1968) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.6.1.36 |
| ExPASy - ENZYME nomenclature database: | 2.6.1.36 |
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