KEGG   ENZYME: 2.6.1.44Help
Entry
EC 2.6.1.44                 Enzyme                                 

Name
alanine---glyoxylate transaminase;
AGT;
alanine-glyoxylate aminotransferase;
alanine-glyoxylic aminotransferase;
L-alanine-glycine transaminase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-alanine:glyoxylate aminotransferase
Reaction(IUBMB)
L-alanine + glyoxylate = pyruvate + glycine [RN:R00369]
Reaction(KEGG)
R00369;
(other) R00372 R10992
Show
Substrate
L-alanine [CPD:C00041];
glyoxylate [CPD:C00048]
Product
pyruvate [CPD:C00022];
glycine [CPD:C00037]
Comment
A pyridoxal-phosphate protein. With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate. A second component also catalyses the reaction of EC 2.6.1.51 serine---pyruvate transaminase.
History
EC 2.6.1.44 created 1972, modified 1982
Pathway
ec00250  Alanine, aspartate and glutamate metabolism
ec00260  Glycine, serine and threonine metabolism
ec00270  Cysteine and methionine metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K00827  alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
K00830  alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
K14272  glutamate--glyoxylate aminotransferase
Genes
HSA: 189(AGXT) 64902(AGXT2)
PTR: 460073(AGXT) 471573(AGXT2)
PPS: 100982568(AGXT2) 100993087(AGXT)
GGO: 101147587(AGXT2) 101152477(AGXT)
PON: 100171524(AGXT2) 100171897(AGXT)
NLE: 100583132(AGXT) 100607531(AGXT2)
MCC: 699250(AGXT2) 699941(AGXT)
MCF: 102132786(AGXT) 102140666(AGXT2)
CSAB: 103215117(AGXT2) 103218227(AGXT)
RRO: 104673090(AGXT) 104678746(AGXT2)
RBB: 108521078(AGXT) 108543800(AGXT2)
CJC: 100390388(AGXT) 100403023(AGXT2)
SBQ: 101031290(AGXT) 101045858(AGXT2)
MMU: 11611(Agxt) 268782(Agxt2)
RNO: 24792(Agxt) 83784(Agxt2)
CGE: 100759906(Agxt2) 100771278(Agxt)
NGI: 103730838(Agxt) 103735910(Agxt2)
HGL: 101709143(Agxt) 101714498(Agxt2)
CCAN: 109690881(Agxt2) 109698707(Agxt)
OCU: 100009147(AGXT) 100352336(AGXT2)
TUP: 102487945(AGXT) 102501713(AGXT2)
CFA: 100855679 607355 612589(AGXT2)
AML: 100477831(AGXT) 100482092(AGXT2)
UMR: 103662813(AGXT) 103664720(AGXT2)
ORO: 101362087(AGXT) 101375130(AGXT2)
FCA: 101097947(AGXT2) 727692(AGXT)
PTG: 102960731(AGXT) 102966139(AGXT2)
AJU: 106980604(AGXT2) 106984612(AGXT)
BTA: 521553(AGXT2) 789572(AGXT)
BOM: 102268165(AGXT) 102269782(AGXT2)
BIU: 109556593(AGXT) 109575007(AGXT2)
PHD: 102320044(AGXT2)
CHX: 102176828(AGXT2) 102187185(AGXT)
OAS: 101103446(AGXT) 101111660(AGXT2)
SSC: 100513890(AGXT2) 100517616(AGXT)
CFR: 102506707(AGXT) 102515152(AGXT2)
CDK: 105087007(AGXT2) 105096182(AGXT)
BACU: 103010305 103010921(AGXT2)
LVE: 103080731(AGXT2) 103081833
OOR: 101275910(AGXT2) 101288519(AGXT)
ECB: 100053849(AGXT2) 100067459(AGXT)
EPZ: 103545309(AGXT2) 103560431(AGXT)
EAI: 106824782(AGXT2) 106832216(AGXT)
MYB: 102239222(AGXT2) 102243500(AGXT)
MYD: 102764532(AGXT) 102773052(AGXT2)
HAI: 109374113(AGXT) 109385510(AGXT2)
RSS: 109434616(AGXT) 109450224(AGXT2)
PALE: 102888844(AGXT2) 102897995(AGXT)
LAV: 100663089(AGXT) 100668434(AGXT2)
MDO: 100020759(AGXT2) 100616909(AGXT)
SHR: 100917044(AGXT2) 100921337(AGXT)
OAA: 100078063(AGXT2) 100080454(AGXT)
GGA: 431666(AGXT2) 770344(AGXT)
MGP: 100541842(AGXT2) 100543344(AGXT)
CJO: 107305776(AGXT2) 107318004(AGXT)
APLA: 101789792(AGXT) 101799853(AGXT2)
ACYG: 106036349(AGXT2) 106039153(AGXT)
TGU: 100230972(AGXT2) 100232024(AGXT)
GFR: 102033340(AGXT2) 102037730(AGXT)
FAB: 101810573(AGXT2) 101817935(AGXT)
PHI: 102109437(AGXT2) 102111727(AGXT)
PMAJ: 107198191(AGXT2) 107208550(AGXT)
CCW: 104686756(AGXT2) 104693080(AGXT)
FPG: 101911080(AGXT2) 101924050(AGXT)
FCH: 102049112(AGXT) 102052632(AGXT2)
CLV: 102084145(AGXT) 102087277(AGXT2)
EGZ: 104131298(AGXT) 104133922(AGXT2)
AAM: 106482172(AGXT) 106499541(AGXT2)
ASN: 102375742(AGXT2) 102379808(AGXT)
AMJ: 102559340(AGXT2) 102572593(AGXT)
PSS: 102449032(AGXT2) 106731855(AGXT)
CMY: 102930944(AGXT2) 102946946
CPIC: 101937486(AGXT2) 101942906(AGXT)
ACS: 100559450(agxt) 100565387(agxt2)
PVT: 110075840(AGXT) 110080093(AGXT2)
PBI: 103060614(AGXT2) 103062103(AGXT)
GJA: 107107502(AGXT2) 107123591(AGXT)
XLA: 108705425(agxt2.S) 108718166(agxt.S) 108718414(agxt2.L) 398137(agxt.L)
XTR: 100491739(agxt2) 448338(agxt)
NPR: 108792653(AGXT2) 108796432(AGXT)
DRE: 436603(agxta) 619269(agxt2) 79378(agxtb)
IPU: 108272030(agxt) 108278136 108279281(agxt2)
XMA: 102217588(agxt2) 102218672 102227198(agxt)
BPEC: 110154705(agxt) 110158361 110160563(agxt2)
LCM: 102356225(AGXT2) 102364803(AGXT)
CMK: 103188322(agxt)
CIN: 100178847
APLC: 110989783
DME: Dmel_CG11241(CG11241) Dmel_CG3926(Spat)
DSI: Dsimw501_GD12056(Dsim_GD12056) Dsimw501_GD16801(Dsim_GD16801)
DYA: Dyak_GE16753(Dyak_Spat) Dyak_GE19492
SOC: 105195042
PBAR: 105429600
HST: 105183838
PGC: 109864093
PXY: 105394913
API: 100163196
ZNE: 110828279
TUT: 107366508
CEL: CELE_T09B4.8(T09B4.8) CELE_T14D7.1(agxt-1)
OBI: 106882838
HMG: 100197706
ATH: AT1G23310(GGT1) AT1G70580(AOAT2) AT2G13360(AGT) AT2G38400(AGT3) AT3G08860(PYD4) AT4G39660(AGT2)
LJA: Lj1g3v2444980.1(Lj1g3v2444980.1) Lj2g3v1415440.1(Lj2g3v1415440.1) Lj2g3v1415440.2(Lj2g3v1415440.2) Lj2g3v1415440.3(Lj2g3v1415440.3) Lj2g3v3058530.1(Lj2g3v3058530.1) Lj4g3v2800580.1(Lj4g3v2800580.1) Lj6g3v0937010.1(Lj6g3v0937010.1)
DOSA: Os03t0171900-01(Os03g0171900) Os03t0338000-01(Os03g0338000) Os05t0475400-01(Os05g0475400) Os07t0108300-01(Os07g0108300) Os08t0502700-01(Os08g0502700)
ATS: 109734653(LOC109734653) 109747472(LOC109747472) 109754438(LOC109754438) 109772808(LOC109772808) 109784440(LOC109784440)
SCE: YFL030W(AGX1)
KMX: KLMA_20304(AGX1)
NCS: NCAS_0C03790(NCAS0C03790)
NDI: NDAI_0G03130(NDAI0G03130)
TPF: TPHA_0D00400(TPHA0D00400)
TBL: TBLA_0G03410(TBLA0G03410)
TDL: TDEL_0C00620(TDEL0C00620)
KAF: KAFR_0C03500(KAFR0C03500)
CAUR: QG37_06169
SLB: AWJ20_5243(AGX1)
NCR: NCU01821
NTE: NEUTE1DRAFT130518(NEUTE1DRAFT_130518)
MGR: MGG_02525
MAW: MAC_03614
MAJ: MAA_02574
CMT: CCM_00200
BFU: BCIN_14g00830(Bcagx1)
MBE: MBM_00466
ANI: AN1342.2
ANG: ANI_1_146074(An08g01000)
ABE: ARB_08028
TVE: TRV_04343
PTE: PTT_19689
CNE: CNL05470
CNB: CNBI1360
HIR: HETIRDRAFT_142962(AGT1)
ABP: AGABI1DRAFT132065(AGABI1DRAFT_132065) AGABI1DRAFT83342(AGABI1DRAFT_83342)
ABV: AGABI2DRAFT151665(AGABI2DRAFT_151665) AGABI2DRAFT180088(AGABI2DRAFT_180088)
MGL: MGL_0855
DDI: DDB_G0289923(agxt)
DFA: DFA_02451(agxt)
SPAR: SPRG_13929
PSHI: SAMEA2665130_2990(pucG)
DKO: I596_1563
VCH: VC0392
VCS: MS6_0246
VCI: O3Y_01805
VVU: VV1_1425
VVY: VV2958
VPA: VP2714
VPB: VPBB_2534
VAG: N646_1805
VSP: VS_0318
VAN: VAA_01746
VSC: VSVS12_00580(agxT)
VTA: A2727
VFI: VF_0339
PPR: PBPRA3292(SYNW1075)
PSTT: CH92_05385
PAR: Psyc_1388(sgaA)
PSYC: DABAL43B_1131(sgaA)
SON: SO_4343(agxT)
SDN: Sden_0404
SFR: Sfri_0426
SAZ: Sama_3277
SBL: Sbal_4027
SLO: Shew_0294
SSE: Ssed_4160
SPL: Spea_0350
SHL: Shal_3939
SWD: Swoo_0447
SWP: swp_0364
SVO: SVI_3863
PAT: Patl_2043
MBS: MRBBS_0358(sgaA) MRBBS_0374(sgaA)
AMAL: I607_09665
AMAE: I876_10130
AMAO: I634_10075
AMAD: I636_10275
AMAI: I635_10670
AMAG: I533_09900
AMAC: MASE_09565
AAUS: EP12_10230
GPS: C427_2940
FBL: Fbal_3643
MVS: MVIS_4262
MCA: MCA1406(sgaA)
MAH: MEALZ_3218(sgaA)
CYQ: Q91_1512
CZA: CYCME_0947(sgaA)
TIG: THII_1889
NOC: Noc_2128
NHL: Nhal_2764
NWA: Nwat_0960
TEE: Tel_06035
NTT: TAO_1292
TGR: Tgr7_1551
TKM: TK90_1895
TNI: TVNIR_2885(pucG_[H])
TVR: TVD_04205
HCH: HCH_05345
HAM: HALO1118
SLIM: SCL_0424
RMA: Rmag_0312
VOK: COSY_0293
ENM: EBS_0809
REH: H16_B1170(h16_B1170)
CNC: CNE_2c11310(sgaA)
RME: Rmet_5630(sgaA)
BXE: Bxe_B3001
BXB: DR64_5330
BFN: OI25_5414
PNU: Pnuc_0602
PPNO: DA70_23550
PPNM: LV28_07160
PPUL: RO07_01270
PSPU: NA29_10420
PAPI: SG18_01455
BPER: BN118_3316
BPA: BPP4201
BPAR: BN117_4271
BBR: BB4671
BPT: Bpet4350
PUT: PT7_1574
POL: Bpro_0548
DAC: Daci_3052
RTA: Rta_16260
HYB: Q5W_07110
MPT: Mpe_A3261
HAR: HEAR2731(sgaA)
MMS: mma_0436
CFU: CFU_0046(sgaA)
CARE: LT85_0048
OFO: BRW83_0220(pucG_1) BRW83_0558(pucG_2)
NEU: NE0034
NET: Neut_0200
METR: BSY238_258
TBD: Tbd_2509
SLT: Slit_0824
BPRC: D521_0472
DVU: DVU3121
DVL: Dvul_0262
DDS: Ddes_0641
ADE: Adeh_2994
MXA: MXAN_0256
HOH: Hoch_1789
MLO: mlr1322
MES: Meso_3308
SME: SMa1495 SMa2139(sgaA)
SMER: DU99_21930
SMD: Smed_5312
SFH: SFHH103_02473(sgaA)
SFD: USDA257_c17720(sgaA1) USDA257_c20700(pucG) USDA257_c22040(sgaA2)
REL: REMIM1_PF00835(sgaA)
REP: IE4803_CH03647(sgaA)
RPA: RPA0789
RPB: RPB_4629
RPC: RPC_4689
RPD: RPD_0780
RPE: RPE_0897
RPT: Rpal_0857
NWI: Nwi_2413
NHA: Nham_2804
OCG: OCA5_c13760(sgaA1) OCA5_c13780(sgaA2)
OCO: OCA4_c13760(sgaA1) OCA4_c13780(sgaA2)
SNO: Snov_2530
MEA: Mex_1p1726(sga) Mex_1p4592(sga)
MDI: METDI2478(sga) METDI5202(sga)
MOR: MOC_4194
MAQU: Maq22A_c19285(sga)
BID: Bind_3524
HMC: HYPMC_3870(sga) HYPMC_4396(sga)
MSC: BN69_1178
MCG: GL4_3378
HDI: HDIA_3040
RBM: TEF_05510
RSP: RSP_0245
RDE: RD1_1750(sgaA) RD1_2892(sgaA)
KVU: EIO_2210
KVL: KVU_1756
PGD: Gal_00997
OTM: OSB_08310
PTP: RCA23_c09760(sgaA1) RCA23_c28310(sgaA2)
RSU: NHU_00509
SPHD: HY78_29925
SSY: SLG_07590
AMV: ACMV_14160(sgaA) ACMV_P1_00050(sgaA)
MAG: amb4448
MAGX: XM1_0741(agxt)
MAGN: WV31_12065
MAGQ: MGMAQ_2502(agxt)
BTS: Btus_1044
STH: STH3178
SAY: TPY_0212
TACI: TDSAC_0255
LPIL: LIP_2919
SALU: DC74_226
SALL: SAZ_01595
SFK: KY5_0746c
ARM: ART_1825
AAU: AAur_3518
KRH: KRH_19950
NCA: Noca_3274
NAL: B005_5124
MMAR: MODMU_5164
SEN: SACE_3639
AJA: AJAP_22150(sgaA)
PDX: Psed_1785
PSEE: FRP1_06960
PSEH: XF36_07780
KAL: KALB_2700
ACTI: UA75_10300
ACAD: UA74_10325
ALL: CRK58092
RXY: Rxyl_0923
SYW: SYNW1075(spt)
SYC: syc1934_c(spt)
SYG: sync_1566
SYR: SynRCC307_1294(spt)
SYX: SynWH7803_1345(spt)
SYNR: KR49_02915
SYND: KR52_10595
SYH: Syncc8109_1473(spt)
PMA: Pro_1037
PMM: PMM0919(spt)
PMT: PMT_0600
PMB: A9601_09411(spt)
PMC: P9515_10021(spt)
PMF: P9303_16451(spt)
PMG: P9301_09401(spt)
PMH: P9215_09711(spt)
PMJ: P9211_10251(spt)
PME: NATL1_07741(spt)
PRC: EW14_0972
PRM: EW15_0824
AMR: AM1_2262
CYT: cce_2871
ANA: alr1004
AVA: Ava_5058
CALH: IJ00_23560
PBF: CFX0092_A2936(pucG)
DRA: DR_1350
DGE: Dgeo_1114
TRA: Trad_1349
TTH: TT_C1813
TTJ: TTHA0173
TAQ: TO73_0239
MRB: Mrub_0738
MIN: Minf_1332
PSL: Psta_2949
PLS: VT03_12840(pucG)
FMR: Fuma_04774(pucG)
GES: VT84_16000(pucG)
IPA: Isop_3726
SACI: Sinac_2608
ABAC: LuPra_02136(pucG)
TLI: Tlie_0500
GAU: GAU_3795(sgaA)
DDO: I597_2816
TMAR: MARIT_2551
NDE: NIDE1160
NMV: NITMOv2_1039(pucG)
NJA: NSJP_2147(pucG)
HHB: Hhub_2839
HMA: rrnAC1999(spaT)
HHI: HAH_2501(spaT)
NPH: NP_2578A
HVO: HVO_2671
HME: HFX_2689
HLA: Hlac_1765
HTU: Htur_1862
NMG: Nmag_0019
NAT: NJ7G_2948
SALI: L593_05655
PCL: Pcal_1612
PAS: Pars_1870
 » show all
Taxonomy
Reference
1  [PMID:629740]
  Authors
Noguchi T, Okuno E, Takada Y, Minatogawa Y, Okai K, Kido R.
  Title
Characteristics of hepatic alanine-glyoxylate aminotransferase in different mammalian species.
  Journal
Biochem J 169:113-22 (1978)
Reference
2  [PMID:6803844]
  Authors
Okuno E, Minatogawa Y, Kido R.
  Title
Co-purification of alanine-glyoxylate aminotransferase with 2-aminobutyrate aminotransferase in rat kidney.
  Journal
Biochim Biophys Acta 715:97-104 (1982)
DOI:10.1016/0304-4165(82)90054-X
Reference
3  [PMID:6038488]
  Authors
Thompson JS, Richardson KE.
  Title
Isolation and characterization of an L-alanine: glyoxylate aminotransferase from human liver.
  Journal
J Biol Chem 242:3614-9 (1967)
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.44
IUBMB Enzyme Nomenclature: 2.6.1.44
ExPASy - ENZYME nomenclature database: 2.6.1.44
BRENDA, the Enzyme Database: 2.6.1.44
CAS: 9015-67-2

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