KEGG   ENZYME: 2.6.1.64Help
Entry
EC 2.6.1.64                 Enzyme                                 

Name
glutamine---phenylpyruvate transaminase;
glutamine transaminase K;
glutamine-phenylpyruvate aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-glutamine:phenylpyruvate aminotransferase
Reaction(IUBMB)
L-glutamine + phenylpyruvate = 2-oxoglutaramate + L-phenylalanine [RN:R01375]
Reaction(KEGG)
Substrate
L-glutamine [CPD:C00064];
phenylpyruvate [CPD:C00166]
Product
2-oxoglutaramate [CPD:C00940];
L-phenylalanine [CPD:C00079]
Comment
A pyridoxal-phosphate protein. L-Methionine, L-histidine and L-tyrosine can act as donors. The enzyme has little activity on pyruvate and glyoxylate (cf. EC 2.6.1.15 glutamine---pyruvate transaminase).
History
EC 2.6.1.64 created 1984
Orthology
K00816  kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase
Genes
HSA: 56267(KYAT3) 883(KYAT1)
PTR: 456999(KYAT3) 473069(KYAT1)
PPS: 100980672(KYAT1) 100993985(KYAT3)
GGO: 101128027(KYAT3) 101137144(KYAT1)
PON: 100436953(KYAT3) 100452866(KYAT1)
NLE: 100579800(KYAT3) 100598335(KYAT1)
MCC: 114669740(KYAT1) 694023(KYAT3) 717142
MCF: 101925086(KYAT3) 102142392(KYAT1)
CSAB: 103224481(KYAT3) 103239781(KYAT1)
RRO: 104660517(KYAT1) 104664603(KYAT3)
RBB: 108512836(KYAT1) 108514569(KYAT3)
CJC: 100390682(KYAT1) 100392205(KYAT3)
SBQ: 101034905(CCBL1) 101049363(CCBL2)
MMU: 229905(Kyat3) 70266(Kyat1)
MCAL: 110290062(Kyat1) 110290637(Kyat3)
MPAH: 110318657(Kyat1) 110320405(Kyat3)
RNO: 311844(Kyat1) 541589(Kyat3)
MUN: 110552266(Kyat3) 110555182(Kyat1)
CGE: 100769821(Kyat1) 100771070(Kyat3)
NGI: 103730106(Kyat3) 103742867(Kyat1)
HGL: 101701445(Kyat3) 101714047(Ccbl1)
CCAN: 109682136(Kyat3) 109697703(Kyat1)
OCU: 100351221(KYAT1) 100358799(KYAT3)
TUP: 102484200(KYAT3) 102492301(KYAT1)
CFA: 479959(KYAT3) 491310(KYAT1)
VVP: 112924506(KYAT3) 112927954(KYAT1)
AML: 100466080(KYAT3) 100484335(KYAT1)
UMR: 103662922(KYAT3) 103670433(KYAT1)
UAH: 113254441(KYAT3) 113266490(KYAT1)
ORO: 101379355(CCBL2) 101381784(CCBL1)
FCA: 101082171(KYAT3) 101082605(KYAT1)
PTG: 102956075(KYAT1) 102960707(KYAT3)
PPAD: 109246230(KYAT3) 109250056(KYAT1)
AJU: 106966305(KYAT1) 106968046(KYAT3)
BTA: 104968656 508712(KYAT3) 528582(CCBL1)
BOM: 102268017(KYAT3) 102274277(KYAT1) 102274974
BIU: 109556093(KYAT3) 109563538 109566527(KYAT1)
BBUB: 102391958(KYAT3) 102400140(KYAT1)
CHX: 102180605(KYAT1) 102182368(KYAT3)
SSC: 100157176(KYAT3) 100515071(KYAT1)
CFR: 102514713(KYAT1) 102522240(KYAT3)
CDK: 105084526(KYAT3) 105092558(KYAT1)
BACU: 103001193(KYAT3) 103010164(KYAT1)
LVE: 103073927(KYAT1) 103090268(KYAT3)
OOR: 101285560(CCBL2) 101290033(CCBL1)
DLE: 111164035(KYAT3) 111177147(KYAT1)
PCAD: 102983157(KYAT3) 102996912(KYAT1)
ECB: 100052141(KYAT3) 100070151(KYAT1)
EPZ: 103550870(KYAT1) 103557170(KYAT3)
EAI: 106831581(KYAT3) 106845422(KYAT1)
MYB: 102246710(KYAT1) 102246937(KYAT3)
MYD: 102770113(KYAT1) 102774189(KYAT3)
MNA: 107524667(CCBL1) 107535764(CCBL2)
HAI: 109376722(KYAT3) 109382267(KYAT1)
DRO: 112306314(KYAT1) 112309337(KYAT3)
PALE: 102885606(KYAT3) 102890346(KYAT1)
RAY: 107504518(CCBL1) 107512700(CCBL2)
MJV: 108393128(KYAT3) 108395766(KYAT1)
LAV: 100674418(KYAT1) 100676040(KYAT3)
MDO: 100013642(KYAT1) 100027687(KYAT3)
SHR: 100925132(KYAT1) 100928200(KYAT3)
PCW: 110193638(KYAT1) 110210007(KYAT3)
OAA: 100074153(KYAT1) 100074828(KYAT3)
GGA: 417202(CCBL1) 424517(KYAT3)
MGP: 100545698(KYAT1) 100546759(KYAT3)
CJO: 107317420(KYAT3) 107321728(KYAT1)
NMEL: 110402407(KYAT3) 110407085(KYAT1)
APLA: 101796959(KYAT3) 101804188(KYAT1)
ACYG: 106034104(CCBL2) 106047313(CCBL1)
TGU: 100223564(KYAT3) 100226378(KYAT1)
LSR: 110468554(KYAT3) 110482286(KYAT1)
SCAN: 103814906(KYAT3) 103819020(KYAT1)
GFR: 102043066(KYAT3) 102045568(KYAT1)
FAB: 101809203(KYAT1) 101816765(KYAT3)
PHI: 102108384(KYAT3) 102109435(KYAT1)
PMAJ: 107207980(KYAT3) 107212063(KYAT1)
CCAE: 111932822(KYAT3) 111936982(KYAT1)
CCW: 104688281(KYAT1) 104695321(KYAT3)
ETL: 114054522(KYAT1) 114057091(KYAT3)
FPG: 101923826(KYAT3) 101924602(KYAT1)
FCH: 102052592(KYAT1) 102055107(KYAT3)
CLV: 102092812(KYAT3) 102097970(KYAT1)
EGZ: 104122512(CCBL1) 104122910(CCBL2)
NNI: 104015478(CCBL2) 104023148(CCBL1)
ACUN: 113482894(KYAT3) 113486546(KYAT1)
PADL: 103915302(CCBL1) 103925131(CCBL2)
AAM: 106490298(KYAT1) 106499802(KYAT3)
ASN: 102377511(KYAT3) 102381063(KYAT1)
AMJ: 102564187(KYAT1) 102574637(KYAT3)
PSS: 102446036(KYAT1) 102459761(KYAT3)
CMY: 102931085(KYAT1) 102947846(KYAT3)
CPIC: 101948590(KYAT3) 101949140(KYAT1)
ACS: 100555601(kyat3)
PVT: 110079452(KYAT3) 110079688(KYAT1)
PBI: 103054557(KYAT3) 103058068(KYAT1)
TSR: 106542068(CCBL1) 106546061(CCBL2)
PMUA: 114589595(KYAT1) 114598781(KYAT3)
GJA: 107115481(KYAT1) 107126241(KYAT3)
XLA: 108715667(kyat3.S) 380432(kyat3.L) 734936(kyat1.L)
XTR: 496736(kyat1)
NPR: 108791027(KYAT3) 108794311(KYAT1)
DRE: 393315(ccbl2) 791592(kyat1)
AMEX: 103027162(kyat3) 103046817(kyat1)
EEE: 113570275 113584540(kyat3)
TRU: 101064758(kyat1) 101066451
LCO: 104931917(kyat3) 104939087(kyat1)
NCC: 104946129(ccbl1) 104955761(ccbl2)
MZE: 101466800(kyat1) 101486988(kyat3)
ONL: 100694072(kyat1) 100694678(kyat3)
OLA: 101164171(kyat1) 101173380
XMA: 102235261(kyat3) 102237088(kyat1)
XCO: 114149155(kyat1) 114151606(kyat3)
PRET: 103463971(kyat3) 103473416(kyat1)
CVG: 107082414 107089769(ccbl1)
NFU: 107374788(ccbl1) 107397216(ccbl2)
KMR: 108231028(kyat1) 108241208(kyat3)
AOCE: 111564084(kyat1) 111575097(kyat3)
CSEM: 103376809(kyat3) 103390101(kyat1)
POV: 109625862(kyat3) 109626496(kyat1)
LCF: 108874059 108874060(kyat1) 108878962(kyat3)
SDU: 111231920(kyat3) 111237361(kyat1)
HCQ: 109517170(kyat1) 109529744(kyat3)
MALB: 109965770(kyat3) 109971345(kyat1)
SASA: 100195431(kat3) 106569847
OTW: 112220099(kyat1) 112251473(kyat3)
SALP: 111961864(kyat1) 112071986(kyat3)
ELS: 105015286(kyat1) 105030533(kyat3)
SFM: 108927270 108927271(kyat1)
PKI: 111841854(kyat1) 111854627(kyat3)
LCM: 102348380(KYAT1) 102366870(KYAT3)
CMK: 103171755(kyat1) 103174679(kyat3)
RTP: 109935627(kyat1) 109936984(kyat3)
CIN: 100186481
SPU: 593717
APLC: 110981090
SKO: 102808740
DME: Dmel_CG6950(Kyat)
DER: 6553988
DSI: Dsimw501_GD20629(Dsim_GD20629)
DPE: 6594315
DWI: 6650503
DAZ: 108620865
DNV: 108654748
DHE: 111593314
MDE: 101891461
LCQ: 111678011
AAG: 5564787
AALB: 109417150
AME: 724811
BIM: 100744283
BTER: 100644987
CCAL: 108633067
OBB: 114874999
SOC: 105199950
MPHA: 105834301
AEC: 105149700
ACEP: 105618986
PBAR: 105433236
VEM: 105570617
HST: 105180580
DQU: 106748643
LHU: 105673051
PGC: 109856505
OBO: 105276089
PCF: 106789106
NVI: 100119206
DPA: 109532996
ATD: 109597412
NVL: 108565563
BMOR: 101742893
PMAC: 106711437
PRAP: 110999630
HAW: 110381053
PXY: 105380713
CLEC: 106666336
ZNE: 110837661
PVM: 113806416
DPTE: 113793296
CSCU: 111641275
PTEP: 107438209
CEL: CELE_F28H6.3(nkat-1) CELE_R03A10.4(nkat-3)
CBR: CBG07704(Cbr-nkat-3) CBG10259
BMY: Bm1_10490
PCAN: 112576260
OBI: 106876997
SHX: MS3_06559
EPA: 110244036
PDAM: 113686698
SPIS: 111323701
DGT: 114518840
AQU: 100641141
DDI: DDB_G0287269(ccbl)
DFA: DFA_11928(ccbl)
SMIN: v1.2.018754.t1(symbB.v1.2.018754.t1)
NGD: NGA_0728200(CCBL)
 » show all
Taxonomy
Reference
1  [PMID:727444]
  Authors
Cooper AJ.
  Title
Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and alpha-keto-gamma-methiolbutyrate.
  Journal
Anal Biochem 89:451-60 (1978)
DOI:10.1016/0003-2697(78)90374-3
Reference
2  [PMID:4822504]
  Authors
Cooper AJ, Meister A.
  Title
Isolation and properties of a new glutamine transaminase from rat kidney.
  Journal
J Biol Chem 249:2554-61 (1974)
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.64
IUBMB Enzyme Nomenclature: 2.6.1.64
ExPASy - ENZYME nomenclature database: 2.6.1.64
BRENDA, the Enzyme Database: 2.6.1.64
CAS: 68518-06-9

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