KEGG   ENZYME: 2.6.1.83Help
Entry
EC 2.6.1.83                 Enzyme                                 

Name
LL-diaminopimelate aminotransferase;
LL-diaminopimelate transaminase;
LL-DAP aminotransferase;
LL-DAP-AT
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
LL-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase
Reaction(IUBMB)
LL-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + L-glutamate + H2O [RN:R07613]
Reaction(KEGG)
Substrate
LL-2,6-diaminoheptanedioate [CPD:C00666];
2-oxoglutarate [CPD:C00026]
Product
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate [CPD:C03972];
L-glutamate [CPD:C00025];
H2O [CPD:C00001]
Comment
A pyridoxal-phosphate enzyme. In vivo, the reaction occurs in the opposite direction to that shown above. This is one of the final steps in the lysine-biosynthesis pathway of plants (ranging from mosses to flowering plants). meso-Diaminoheptanedioate, an isomer of LL-2,6-diaminoheptanedioate, and the structurally related compounds lysine and ornithine are not substrates. 2-Oxoglutarate cannot be replaced by oxaloacetate or pyruvate. It is not yet known if the substrate of the biosynthetic reaction is the cyclic or acyclic form of tetrahydropyridine-2,6-dicarboxylate.
History
EC 2.6.1.83 created 2006
Pathway
ec00300  Lysine biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01130  Biosynthesis of antibiotics
Orthology
K10206  LL-diaminopimelate aminotransferase
Genes
RSS: 109441281
ATH: AT2G13810(ALD1) AT4G33680(AGD2)
ALY: ARALYDRAFT_480324 ARALYDRAFT_491312
CRB: 17878288 17891569 17893406
CSAT: 104716783 104721447 104729881 104747291 104747309 104792920 104793629
EUS: EUTSA_v10022684mg EUTSA_v10022686mg EUTSA_v10024872mg
BRP: 103834462 103854764 103861095
BNA: 106361092 106365194 106370770 106405750 106438544 106439752 106441983 106442397 106442399 111204598
BOE: 106295275 106332882 106334809
THJ: 104807195 104819500
LJA: Lj1g3v0652040.1(Lj1g3v0652040.1) Lj4g3v0338190.1(Lj4g3v0338190.1) Lj4g3v0412700.1(Lj4g3v0412700.1) Lj4g3v0412700.2(Lj4g3v0412700.2) Lj6g3v1078410.1(Lj6g3v1078410.1) Lj6g3v2218710.1(Lj6g3v2218710.1)
DOSA: Os03t0299900-01(Os03g0299900)
ATS: 109745247(LOC109745247) 109772860(LOC109772860) 109782348(LOC109782348)
PPP: 112290581
CRE: CHLREDRAFT_129557(DPA1)
APRO: F751_2584
PPU: PP_3786(aspC)
GSU: GSU0162(dapL)
GSK: KN400_0137(dapL)
GME: Gmet_0213(dapL)
GUR: Gura_0238
GLO: Glov_3040
GBM: Gbem_4052(dapL)
GEO: Geob_1134(dapL)
GEM: GM21_4142
GEB: GM18_4513
PCA: Pcar_2423(dapL)
PPD: Ppro_3061
DES: DSOUD_0914(dapL)
DEU: DBW_0901
DVU: DVU1655
DVL: Dvul_1431
DVM: DvMF_0361
DDE: Dde_1970
DDS: Ddes_1151
DMA: DMR_22010
DHY: DESAM_22304(dapL)
DGG: DGI_2278
DTR: RSDT_0400(dapL)
DAS: Daes_1551
DPI: BN4_10702(dapL)
PPRF: DPRO_0412(dapL)
LIP: LI0435(aspC)
LIR: LAW_00450(aspC)
DBA: Dbac_0704
DRT: Dret_1351
DPS: DP2165
DSF: UWK_03272
DOL: Dole_2779
DML: Dmul_13730(dapL1)
DAL: Dalk_0414
DTO: TOL2_C03010(dapL)
SAT: SYN_00168
SFU: Sfum_0054
DBR: Deba_1873
OIH: OB2282
GKA: GK0372
GTN: GTNG_0347
GEA: GARCT_00420(dapL_1)
VPN: A21D_02340(dapL_1)
BLR: BRLA_33p000070(alaC)
PMW: B2K_32365
PLV: ERIC2_c24440(dapL)
PRI: PRIO_5105(dapL)
ASOC: CB4_00898(dapL_1)
CAC: CA_C1715
CAE: SMB_G1740(dapL)
CAY: CEA_G1728
CLS: CXIVA_05550(AvtA)
CPAS: Clopa_2442
CPAT: CLPA_c21120(dapL2)
CPAE: CPAST_c21120(dapL2)
CSB: CLSA_c20840(dapL)
CSQ: CSCA_2257
CACE: CACET_c11490(dapL2)
AMT: Amet_1616
AOE: Clos_2023
CTH: Cthe_3101
CSS: Cst_c09590(dapL1)
CSD: Clst_0919
ESR: ES1_03640
ESU: EUS_01380
CCEL: CCDG5_0888(dapL)
RBR: RBR_01390
RCH: RUM_18400
RUM: CK1_18280
RUS: RBI_II00016(dapL)
FPR: FP2_15790
FPA: FPR_20330
BPB: bpr_I2331
BFI: CIY_02000
BHU: bhn_I2144
RIX: RO1_22920
RIM: ROI_10700
COO: CCU_03160
CCT: CC1_06680
ROB: CK5_31360
CPY: Cphy_0631
CSO: CLS_18990
BPRL: CL2_09750
ERT: EUR_26020
ERA: ERE_08100
SLP: Slip_0851
DRM: Dred_1695
DAE: Dtox_2324
PTH: PTH_1799
DAU: Daud_1603
HMO: HM1_0993 HM1_2384(aspB)
AWO: Awo_c17620(aspB2)
TMR: Tmar_0910
SAY: TPY_2829
BPRS: CK3_27440
CHY: CHY_1492
MTA: Moth_0889
ADG: Adeg_1381
TPZ: Tph_c14370(dapL)
CSC: Csac_0772
ATE: Athe_0546
TOC: Toce_1019
TACI: TDSAC_0917
VPR: Vpar_0331
VRM: 44547418_00352(dapL)
MED: MELS_0042
SRI: SELR_16200(dapL)
MHG: MHY_15860
AIN: Acin_0020
LPIL: LIP_1737
CWO: Cwoe_3257
EYY: EGYY_20270(AvtA)
GPA: GPA_02110
AEQ: AEQU_0414
CBAC: JI75_00665
SYN: sll0006(aspC) sll0480
SYY: SYNGTS_2240(aspC) SYNGTS_2621(sll0480)
SYT: SYNGTI_2239(aspC) SYNGTI_2620(sll0480)
SYS: SYNPCCN_2238(aspC) SYNPCCN_2619(sll0480)
SYQ: SYNPCCP_2238(aspC) SYNPCCP_2619(sll0480)
SYJ: D082_03560(aspB) D082_25690(aspC)
SYW: SYNW2147
SYC: syc0687_c(aspB)
SYG: sync_0372(aspB)
CYB: CYB_1262 CYB_1421(aspB)
SYNR: KR49_10560
SYND: KR52_00880
THN: NK55_08255(dapL-1) NK55_08525(dapL-2)
CYI: CBM981_1914(dapL)
LET: O77CONTIG1_00112(dapL_1) O77CONTIG1_04156(dapL_3)
HHG: XM38_042900(dapL_1) XM38_048130(dapL_2)
PMA: Pro_1655
PMM: PMM1500
PMT: PMT_1791
PRC: EW14_1839
PRM: EW15_2004
GVI: glr4108
GLJ: GKIL_3332
DET: DET0739
DEH: cbdbA714
DEV: DhcVS_646
DMC: btf_661
DMD: dcmb_707
DMG: GY50_0626
ATM: ANT_16950
ABAT: CFX1CAM_1252(dapL)
CTR: CT_390(aspC)
CTD: CTDEC_0390(aspC)
CTF: CTDLC_0390(aspC)
CTA: CTA_0425(aspC)
CTY: CTR_3891(dapL)
CRA: CTO_0425
CTRQ: A363_00418
CTB: CTL0646(dapL)
CTL: CTLon_0643(dapL)
CTO: CTL2C_909
CTJ: JALI_3891(dapL)
CTZ: CTB_3891(dapL)
CSW: SW2_3961(dapL)
CES: ESW3_3961(dapL)
CTRB: BOUR_00415
CTEC: EC599_4021(dapL)
CFS: FSW4_3961(dapL)
CFW: FSW5_3961(dapL)
CTFW: SWFP_4191(dapL)
CTCH: O173_02135
CTRI: BN197_3941(dapL)
CTRA: BN442_3941(dapL)
CTCT: CTW3_02130
CMU: TC_0669
CMUR: Y015_03520
CMX: DNC_03400
CMZ: TAC_03520
CPN: CPn0495(aspC)
CPA: CP_0259
CPJ: aspC(aspC)
CPT: CpB0515
CPM: G5S_0579
CPEC: CPE3_0254
CPEO: CPE1_0254
CPER: CPE2_0254
CHB: G5O_0281
CHR: Cpsi_2611
CPSC: B711_0286(dapL)
CPSN: B712_0278(dapL)
CPSB: B595_0285(dapL)
CPSG: B598_0279(dapL)
CPSM: B602_0278(dapL)
CPSI: B599_0277(dapL)
CPSV: B600_0292(dapL)
CPSW: B603_0278(dapL)
CPST: B601_0279(dapL)
CPSD: BN356_2561
CPSA: AO9_01340
CAV: M832_00820(dapL)
CCA: CCA_00249
CAB: CAB245
CABO: AB7_2741
CFE: CF0757(aspC)
PCU: pc0685(aspC)
PNL: PNK_1500(aspc3)
PUV: PUV_02300(dapL)
WCH: wcw_0764(aspC3)
SNG: SNE_A10370(dapL)
OTE: Oter_4620
OBG: Verru16b_00659(dapL)
CAA: Caka_2232
AGL: PYTT_2330
XII: AMD24_00086(dapL)
MIN: Minf_0281
RBA: RB6821(aspC)
PSL: Psta_1914
PIR: VN12_11605(dapL)
PLM: Plim_3995
PLS: VT03_26105(dapL)
PLH: VT85_02200(dapL)
FMR: Fuma_02692(dapL)
TTF: THTE_4258
GES: VT84_35650(dapL)
IPA: Isop_1621
SACI: Sinac_5498
PBOR: BSF38_00047(dapL)
KST: KSMBR1_3548(dapC)
PHM: PSMK_11600(dapL)
PBU: L21SP3_01196(dapL)
PBAS: SMSP2_01242(dapL)
PBP: STSP1_02247(dapL)
VBL: L21SP4_00295(dapL)
LIL: LA_0776
LIE: LIF_A0633
LIC: LIC_12841(ywfG)
LIS: LIL_12933
LBJ: LBJ_0733
LBL: LBL_2347
LBF: LBF_0994
LST: LSS_16046
EMI: Emin_1014
EPO: Epro_0753(dapL) Epro_1058(yfdZ)
ETI: RSTT_600
RSD: TGRD_639
TLI: Tlie_0383
FSC: FSU_2316
GAU: GAU_2121
BTHO: Btheta7330_00528(dapL_1) Btheta7330_02043(dapL_2)
BOA: Bovatus_01201(dapL_1) Bovatus_04052(dapL_2)
BCEL: BcellWH2_01754(dapL_1) BcellWH2_05258(dapL_2)
BACC: BRDCF_p655(dapL)
PMUC: ING2E5A_0030(dapL_1) ING2E5A_2387(dapL_3)
TFO: BFO_1681
PSAC: PSM36_3330 PSM36_3473(dapL)
AFD: Alfi_3051
ASH: AL1_04860
DORI: FH5T_04775
BLQ: L21SP5_02746(dapL)
MBAS: ALGA_3641
CPI: Cpin_1938
FLN: FLA_4514
PHE: Phep_3792
SMIZ: 4412673_01830(dapL)
CHU: CHU_0765
DFE: Dfer_3140
SLI: Slin_6544
FAE: FAES_4479
PSEZ: HME7025_00558(mtnE)
HSW: Hsw_4151
GFO: GFO_0341
GFL: GRFL_2121
FJO: Fjoh_0516
FJG: BB050_02009(dapL)
FPS: FP0250(aspC3)
FBR: FBFL15_2647(aspC3)
ZPR: ZPR_3526
MARM: YQ22_04170
CBAL: M667_08205
CBAT: M666_08245
DDO: I597_2831(dapL)
MLT: VC82_2070
NDO: DDD_1903
WIN: WPG_0724
TJE: TJEJU_3681(yfdZ)
TMAR: MARIT_2626(dapL)
AALG: AREALGSMS7_02473(dapL)
KOS: KORDIASMS9_00250(dapL)
MARF: CJ739_2145
BPI: BPLAN_298(tyrB)
BMM: MADAR_075(tyrB)
BBG: BGIGA_292(tyrB)
BLP: BPAA_302
BLU: K645_1586
AAE: aq_273(aspC4)
HTH: HTH_0357
TAL: Thal_1518
TTK: TST_0694
TLE: Tlet_0024
DTU: Dtur_1080
NDE: NIDE0503(yfdZ)
NMV: NITMOv2_0420(dapL)
NIO: NITINOP_1231(dapL)
NJA: NSJP_1546(dapL)
LFC: LFE_0303
CTHI: THC_0989
MOX: DAMO_2313
MJA: MJ_1391
MMP: MMP1527
MMD: GYY_08480
MAE: Maeo_1494
MVO: Mvol_1096
MTH: MTH_52
METC: MTCT_0053
MWO: MWSIV6_0506(dapL)
METE: tca_00052(dapL)
MST: Msp_0924
MSI: Msm_1455
MRU: mru_0941(dapL)
MEB: Abm4_1220(dapL)
MMIL: sm9_1625(dapL)
MEYE: TL18_07165
MOL: YLM1_0501
METH: MBMB1_0946(dapL)
MFC: BRM9_1120(dapL)
MFI: DSM1535_1774(dapL)
MCUB: MCBB_1330(dapL)
MFV: Mfer_0901
AFU: AF_0409
FPL: Ferp_0809
GAC: GACE_0125
GAH: GAH_00257
MEAR: Mpt1_c00880(dapL)
MARC: AR505_0157
MAC: MA_1712
MBAR: MSBR2_1119
MBAK: MSBR3_0945
MMA: MM_2649
MMAC: MSMAC_1056
METM: MSMTP_1933
MTHE: MSTHC_0158
MTHR: MSTHT_0563
MHOR: MSHOH_2595
MBU: Mbur_1013
MMET: MCMEM_1499
MMH: Mmah_1388
MPY: Mpsy_0364
MTP: Mthe_0801
MCJ: MCON_2418
MHI: Mhar_1754
MHU: Mhun_2943
MLA: Mlab_0633
MPI: Mpet_0703
MBN: Mboo_2096
MPL: Mpal_0037
MPD: MCP_0860
MEZ: Mtc_1410
RCI: RCIX1962(aat-3)
LOKI: Lokiarch_05320(dapL)
 » show all
Taxonomy
Reference
1  [PMID:16361515]
  Authors
Hudson AO, Singh BK, Leustek T, Gilvarg C.
  Title
An LL-diaminopimelate aminotransferase defines a novel variant of the lysine biosynthesis pathway in plants.
  Journal
Plant Physiol 140:292-301 (2006)
DOI:10.1104/pp.105.072629
  Sequence
[ath:AT4G33680] [syn:sll0480]
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.83
IUBMB Enzyme Nomenclature: 2.6.1.83
ExPASy - ENZYME nomenclature database: 2.6.1.83
BRENDA, the Enzyme Database: 2.6.1.83
CAS: 949001-34-7

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