Entry
Name
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase;
dTDP-6-deoxy-D-xylohex-3-uloseaminase;
FdtB;
TDP-3-keto-6-deoxy-D-galactose-3-aminotransferase;
RavAMT;
TDP-3-keto-6-deoxy-D-galactose 3-aminotransferase;
TDP-3-dehydro-6-deoxy-D-galactose 3-aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose:2-oxoglutarate aminotransferase
Reaction(IUBMB)
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-oxoglutarate = dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-glutamate [RN:
R09824 ]
Reaction(KEGG)
Substrate
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose [CPD:
C19947 ];
2-oxoglutarate [CPD:
C00026 ]
Product
dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose [CPD:
C19960 ];
L-glutamate [CPD:
C00025 ]
Comment
A pyridoxal-phosphate protein. The enzyme is involved in the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose. The reaction occurs in the reverse direction.
History
EC 2.6.1.90 created 2011
Pathway
ec00523 Polyketide sugar unit biosynthesis
ec00541 O-Antigen nucleotide sugar biosynthesis
ec01110 Biosynthesis of secondary metabolites
Orthology
K20680 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase
Reference
Authors
Pfoestl A, Hofinger A, Kosma P, Messner P
Title
Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.90
ExPASy - ENZYME nomenclature database: 2.6.1.90