Entry
Name
4-aminobutyrate---pyruvate transaminase;
aminobutyrate aminotransferase (ambiguous);
gamma-aminobutyrate aminotransaminase (ambiguous);
gamma-aminobutyrate transaminase (ambiguous);
gamma-aminobutyric acid aminotransferase (ambiguous);
gamma-aminobutyric acid pyruvate transaminase;
gamma-aminobutyric acid transaminase (ambiguous);
gamma-aminobutyric transaminase (ambiguous);
4-aminobutyrate aminotransferase (ambiguous);
4-aminobutyric acid aminotransferase (ambiguous);
aminobutyrate transaminase (ambiguous);
GABA aminotransferase (ambiguous);
GABA transaminase (ambiguous);
GABA transferase (ambiguous);
POP2 (gene name)
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
4-aminobutanoate:pyruvate aminotransferase
Reaction(IUBMB)
(1) 4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine [RN:
R10178 ];
(2) 4-aminobutanoate + glyoxylate = succinate semialdehyde + glycine [RN:
R10179 ]
Reaction(KEGG)
Substrate
Product
Comment
Requires pyridoxal 5'-phosphate. The enzyme is found in plants that do not have the 2-oxoglutarate dependent enzyme (cf. EC
2.6.1.19 ). The reaction with pyruvate is reversible while the reaction with glyoxylate only takes place in the forward direction.
History
EC 2.6.1.96 created 2012
Pathway
ec00250 Alanine, aspartate and glutamate metabolism
ec01120 Microbial metabolism in diverse environments
Orthology
K16871 4-aminobutyrate---pyruvate transaminase
Genes
CSAT : 104746666 104787216 109124790
EUS : EUTSA_v10020531mg EUTSA_v10020563mg
BRP : 103834779 103869108 103869111
BNA : 106345502 106391515 106391519 106439809 111202360 125602352 125606723
RSZ : 108806639 108833499 108836244
MINC : 123210378 123227273
GHI : 107888213 107908328 107912667 107924570
HSYR : 120165237 120212106
TPRA : 123917634 123917638
LANG : 109325764 109354047 109355542
QSA : O6P43_013773 O6P43_021103
MDM : 103429193 103441440(GABA-T2)
MSYL : 126582849 126611060
CSAV : 115699409 115700623
CSV : 101211530 101219660 101220932
CMO : 103493051 103493054 103502504
BHJ : 120068092 120086780 120086830
MCHA : 111008130 111008301
CMAX : 111477042 111479758 111480372 111483360 111483362 111483363 111483365
CMOS : 111437539 111437540 111437541 111437542 111437544 111442867 111445807 111447381
CPEP : 111787855 111797325 111804476 111809772 111809773 111809774 111809775 111809776
PALZ : 118037280 118052907
SLY : 543873(GABA-TP1) 543874(GABA-TP2) 544258(GABA-TP3)
SPEN : 107005469 107007340 107026604
SOT : 102595558 102596238 102599962
SSTN : 125863002 125863004 125876233
SDUL : 129870802 129871395 129892374
CANN : 107841786 107862720
LBB : 132616734 132636715 132636716
NTA : 107759660 107759965 107784412 107802933 107812914 107821173 107832742
NSY : 104226521 104236859 104250096
NTO : 104088989 104094231 104104015
SSPL : 121745393 121753609 121758910 121811009
SHIS : 125186809 125194135
ECAD : 122600774 122603134
CCAV : 112524455 112527486
CQI : 110681943 110681944 110695106
PSOM : 113279738 113290086
OSA : 4328053(GABA-T) 4336982 4336983(OsJ_16145) 4344928(OsJ_26408)
OBR : 102701536 102702002 102702310
OGL : 127764098 127770635 127770636 127782883
TDC : 119311273 119330264 119338317 119339000 119356197 119365356
TAES : 100682496 123054284 123156993 123161053 123165077 123190180
LPER : 127314577 127336191
LRD : 124672326 124674217 124689175
SBI : 8071169 8072343 8076546
ZMA : 100282236 100286148 103645944
MFLO : 136471950 136493664 136493721 136497452
SITA : 101758155 101781154
PVIR : 120641765 120679028 120682433 120682502 120711754
PHAI : 112897762 112898816
ZOF : 121980556 121984466 122000733 122005022
SMO : SELMODRAFT_177017 SELMODRAFT_270846
PMOS : O165_009765 O165_024215
PSEC : CCOS191_2907(GABA-TP1b)
GAI : IMCC3135_15065 IMCC3135_27785
PDIO : PDMSB3_2401.1(spuC)
BTRM : SAMEA390648703040(tpa_2) SAMEA390648703251(bioA_2)
CDN : BN940_12961 BN940_13021
VAP : Vapar_5230 Vapar_5629
VAM : C4F17_01295 C4F17_28545
XYK : GT347_03105 GT347_10445
XYG : R9X41_13390 R9X41_20245
MESP : C1M53_19140 C1M53_23500
MMEI : LRP31_14625 LRP31_31130
NRH : T8J41_09950 T8J41_19955
MESO : BSQ44_07585 BSQ44_21920
PHT : BLM14_13005 BLM14_29360
SMI : BN406_04030(GABA-TP3) BN406_06293(GABA-TP3)
ECAA : J3R84_20060 J3R84_32195
AGR : AGROH133_11145 AGROH133_14247
ARUI : G6M88_16660 G6M88_20890
ALEG : CFBP4996_15985 CFBP4996_28150
RBQ : J2J99_25440 J2J99_25790
NEN : NCHU2750_32320 NCHU2750_35590 NCHU2750_54570
RFV : RFYW14_03515 RFYW14_04180
OCH : CES85_3010 CES85_3433
BJU : BJ6T_56750 BJ6T_81330
BJP : RN69_27505 RN69_39500
BOT : CIT37_05140 CIT37_33355
BVV : BHK69_00045 BHK69_27605
BOP : AXW83_05045 AXW83_05070 AXW83_12715
BOI : BLM15_17705 BLM15_24705
BOF : FQV39_26240 FQV39_29880
BOSE : RMR04_04325 RMR04_06620
XDI : EZH22_01165 EZH22_15955
APOL : K9D25_11270 K9D25_18425
MRD : Mrad2831_0848 Mrad2831_3217
MAQU : Maq22A_1p33760(bioA) Maq22A_2p42700(bioA)
AUA : M673_19005 M673_21240 M673_22855
NOH : G5V57_09890 G5V57_15790 G5V57_22410
PSTG : E8M01_03660 E8M01_07960 E8M01_14570 E8M01_17225
PHP : PhaeoP97_00901 PhaeoP97_03853
PABY : Ga0080574_TMP1142 Ga0080574_TMP1876
SINL : DSM14862_04268(spuC_3) DSM14862_04320(spuC_4)
SPSE : SULPSESMR1_02511(tpa)
RPEL : N7U68_11540 N7U68_13080
OCD : FHY55_05550 FHY55_15670
TGL : HFZ77_07890 HFZ77_08120
PAMI : JCM7686_1171 JCM7686_1757 JCM7686_2098
PZH : CX676_00775 CX676_08755
PLIA : E4191_13530 E4191_16990
PMAU : CP157_02551(spuC_2)
PMEH : JWJ88_06385 JWJ88_15215
RMB : K529_003700 K529_016625
DAA : AKL17_0232 AKL17_1456
HML : HmaOT1_08250 HmaOT1_09540
PPRU : FDP22_08670 FDP22_11040
PAED : G5B38_10845 G5B38_12415
PALW : PSAL_000240(spuC_1)
HDH : G5B40_10695 G5B40_16810
KNA : B0W47_15385 B0W47_15750
RMUC : FOB66_03025 FOB66_12000
SRF : LHU95_07355 LHU95_09880
RAP : RHOA_5919(spuC) RHOA_6165(spuC)
SHUM : STHU_04430 STHU_26150 STHU_28620 STHU_38920
SVC : STVA_05980 STVA_18280 STVA_27680 STVA_32590
STEL : STAQ_14060 STAQ_26950 STAQ_39730
AOZ : HUE56_10985 HUE56_28285
NCB : C0V82_01300 C0V82_03020
HTQ : FRZ44_19070 FRZ44_39080
ELIO : KO353_03520 KO353_13825
» show all
Taxonomy
Reference
1
Authors
Van Cauwenberghe OR, Shelp BJ.
Title
Biochemical characterization of partially purified gaba:pyruvate transaminase from Nicotiana tabacum.
Journal
Phytochemistry 52:575-581 (1999)
Reference
Authors
Palanivelu R, Brass L, Edlund AF, Preuss D
Title
Pollen tube growth and guidance is regulated by POP2, an Arabidopsis gene that controls GABA levels.
Journal
Sequence
Reference
Authors
Clark SM, Di Leo R, Dhanoa PK, Van Cauwenberghe OR, Mullen RT, Shelp BJ
Title
Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate.
Journal
Sequence
Reference
Authors
Clark SM, Di Leo R, Van Cauwenberghe OR, Mullen RT, Shelp BJ
Title
Subcellular localization and expression of multiple tomato gamma-aminobutyrate transaminases that utilize both pyruvate and glyoxylate.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.96
ExPASy - ENZYME nomenclature database: 2.6.1.96