Entry |
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Name |
ADP-specific phosphofructokinase;
ADP-6-phosphofructokinase;
ADP-dependent phosphofructokinase
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Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
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Sysname |
ADP:D-fructose-6-phosphate 1-phosphotransferase
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Reaction(IUBMB) |
ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate [RN: R05805]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
ADP can be replaced by GDP, ATP and GTP, to a limited extent. Divalent cations are necessary for activity, with Mg2+ followed by Co2+ being the most effective.
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History |
EC 2.7.1.146 created 2001
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Pathway |
ec00010 | Glycolysis / Gluconeogenesis |
ec01110 | Biosynthesis of secondary metabolites |
ec01120 | Microbial metabolism in diverse environments |
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Orthology |
K00918 | ADP-dependent phosphofructokinase/glucokinase |
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Genes |
» show all
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Reference |
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Authors |
Tuininga JE, Verhees CH, van der Oost J, Kengen SW, Stams AJ, de Vos WM. |
Title |
Molecular and biochemical characterization of the ADP-dependent phosphofructokinase from the hyperthermophilic archaeon Pyrococcus furiosus. |
Journal |
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Sequence |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 2.7.1.146 |
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