| Entry |
|
|---|
| Name |
ADP-specific phosphofructokinase;
ADP-6-phosphofructokinase, ADP-dependent phosphofructokinase
|
|---|
| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
 |
|---|
| Sysname |
ADP:D-fructose-6-phosphate 1-phosphotransferase
|
|---|
| Reaction(IUBMB) |
ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate [RN: R05805]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
|
|---|
| Comment |
ADP can be replaced by GDP, ATP and GTP, to a limited extent. Divalent cations are necessary for activity, with Mg2+ followed by Co2+ being the most effective.
|
|---|
| History |
EC 2.7.1.146 created 2001
|
|---|
| Pathway |
| ec00010 | Glycolysis / Gluconeogenesis |
| ec01110 | Biosynthesis of secondary metabolites |
| ec01120 | Microbial metabolism in diverse environments |
| ec01130 | Biosynthesis of antibiotics |
|
|---|
| Orthology |
| K00918 | ADP-dependent phosphofructokinase/glucokinase |
|
|---|
| Genes |
» show all
 |
|---|
| Reference |
|
|---|
| Authors |
Tuininga JE, Verhees CH, van der Oost J, Kengen SW, Stams AJ, de Vos WM. |
|---|
| Title |
Molecular and biochemical characterization of the ADP-dependent phosphofructokinase from the hyperthermophilic archaeon Pyrococcus furiosus. |
|---|
| Journal |
|
|---|
| Sequence |
|
|---|
| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.7.1.146 |
|
|---|
