KEGG   ENZYME: 2.7.1.161
Entry
EC 2.7.1.161                Enzyme                                 

Name
CTP-dependent riboflavin kinase;
Methanocaldococcus jannaschii Mj0056;
Mj0056
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
CTP:riboflavin 5'-phosphotransferase
Reaction(IUBMB)
CTP + riboflavin = CDP + FMN [RN:R08574]
Reaction(KEGG)
R08574
Substrate
CTP [CPD:C00063];
riboflavin [CPD:C00255]
Product
CDP [CPD:C00112];
FMN [CPD:C00061]
Comment
This archaeal enzyme differs from EC 2.7.1.26, riboflavin kinase, in using CTP as the donor nucleotide. UTP, but not ATP or GTP, can also act as a phosphate donor but it is at least an order of magnitude less efficient than CTP.
History
EC 2.7.1.161 created 2008
Pathway
ec00740  Riboflavin metabolism
ec01100  Metabolic pathways
Orthology
K07732  riboflavin kinase, archaea type
Genes
HCAM: I4484_13040
EBA: ebA3131
ABRE: pbN1_19130
APET: ToN1_08940
AZA: AZKH_p0138
AZI: AzCIB_2693
AZD: CDA09_14630
TAK: Tharo_2783
DDZ: DSYM_29640
DOV: DSCO28_49160
STH: STH673
MJA: MJ_0056
MESG: MLAUSG7_0930(ribK)
MMP: MMP0184
MMD: GYY_00935
MMAK: MMKA1_01880(rfk)
MMAO: MMOS7_02140(rfk)
MMAD: MMJJ_09010
MAE: Maeo_0925
MVO: Mvol_1472
MTH: MTH_1500
METC: MTCT_1364
MWO: MWSIV6_0041(ribK)
METE: tca_01447
MST: Msp_0177
MRU: mru_2174(ribK)
MSI: Msm_1257
MEB: Abm4_0017(ribK)
MMIL: sm9_0008(ribK)
MEYE: TL18_00100
MOL: YLM1_1648
METH: MBMB1_0035
MFC: BRM9_0089(ribK)
MCUB: MCBB_0051(ribK)
MFV: Mfer_0343
MKA: MK1398
AFU: AF_2106
FPL: Ferp_0920
GAC: GACE_0050
GAH: GAH_00799
PFU: PF0988
PFI: PFC_04170
PHO: PH0660(PH0660)
PAB: PAB0917
PYN: PNA2_1275
PYS: Py04_1099
TKO: TK1272
TON: TON_0557
TGA: TGAM_0914
TSI: TSIB_0978
THE: GQS_02300
THA: TAM4_500
THM: CL1_0129
TLT: OCC_08510
THS: TES1_0959
TNU: BD01_0450
TEU: TEU_09890
TCQ: TIRI35C_0934(ribK)
PPAC: PAP_07010
MBAR: MSBR2_1939
MBAK: MSBR3_1972
MAC: MA_0547
MMA: MM_1709
MMAC: MSMAC_1469
METM: MSMTP_2894
MTHR: MSTHT_2081
MTHE: MSTHC_1203
MHOR: MSHOH_3670
MBU: Mbur_1724
MMET: MCMEM_2195
MMH: Mmah_2024
MPY: Mpsy_1944
MCJ: MCON_0442
MHI: Mhar_0833
MHU: Mhun_1259
MLA: Mlab_1629
MEMA: MMAB1_3358(ribK)
MPI: Mpet_0554
MBN: Mboo_0159
MPL: Mpal_2512
MPD: MCP_2669
MEZ: Mtc_0175
RCI: RCIX631
HAL: VNG_2126C
HSL: OE_3964R(ribK)
HHB: Hhub_3414(ribK)
HALH: HTSR_1794
HHSR: HSR6_1863(rfk)
HMA: rrnAC3074
HHI: HAH_0329
NPH: NP_0072A(ribK)
NMO: Nmlp_1367(ribK)
HUT: Huta_2018
HTI: HTIA_1657
HMU: Hmuk_1112
HALL: LC1Hm_0127
HWA: HQ_3236A(ribK)
HWC: Hqrw_3797(ribK)
HVO: HVO_0326(ribK)
HME: HFX_0311
HLA: Hlac_0355
NMG: Nmag_0941(ribK)
NAT: NJ7G_1689
SALI: L593_07815
TAC: Ta1064
TVO: TVG0510159(TVG0510159)
PTO: PTO0969
FAI: FAD_1183
CDIV: CPM_1181
MEAR: Mpt1_c13270(ribK)
MARC: AR505_1679
ABI: Aboo_1119
ACJ: ACAM_1322
SMR: Smar_1200
IHO: Igni_0547
IIS: EYM_00165
DKA: DKAM_0976
TAG: Tagg_0106
IAG: Igag_0233
HBU: Hbut_0506
STO: STK_12800
SSO: SSO0955
SOL: Ssol_1931
SSOA: SULA_1963
SSOL: SULB_1964
SSOF: SULC_1962
SAI: Saci_1332
SID: M164_1255
SII: LD85_1383
SIH: SiH_1216
SIR: SiRe_1134
SIC: SiL_1131
MSE: Msed_1737
MCN: Mcup_0491
AHO: Ahos_1402
CSTY: KN1_24240
STEP: IC006_1163
PAI: PAE2157
PIS: Pisl_0940
PCL: Pcal_1071
PAS: Pars_0815
PYR: P186_0396
POG: Pogu_1517
TNE: Tneu_1345
CMA: Cmaq_1224
TTN: TTX_0185
TUZ: TUZN_1162
VDI: Vdis_2013
VMO: VMUT_0422
TPE: Tpen_0098
ASC: ASAC_1027
ACIA: SE86_06255
NMR: Nmar_1301
NID: NPIRD3C_0824(ribK)
NIN: NADRNF5_0657(ribK)
NCT: NMSP_0389(ribK)
NGA: Ngar_c19280(rfk)
NVN: NVIE_003160(ribK)
NEV: NTE_01635
NCV: NCAV_0987(ribK)
NBV: T478_1053
NDV: NDEV_1634(ribK)
CCAI: NAS2_0385
KCR: Kcr_0996
BARC: AOA65_2401(ribK)
BARB: AOA66_0539(ribK)
NCON: LC1Nh_0881(rfk)
LOKI: Lokiarch_26640(ribK)
PSYT: DSAG12_01900(ribK)
 » show all
Reference
1  [PMID:18073108]
  Authors
Ammelburg M, Hartmann MD, Djuranovic S, Alva V, Koretke KK, Martin J, Sauer G, Truffault V, Zeth K, Lupas AN, Coles M.
  Title
A CTP-dependent archaeal riboflavin kinase forms a bridge in the evolution of cradle-loop barrels.
  Journal
Structure 15:1577-90 (2007)
DOI:10.1016/j.str.2007.09.027
  Sequence
[mja:MJ_0056]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.161
IUBMB Enzyme Nomenclature: 2.7.1.161
ExPASy - ENZYME nomenclature database: 2.7.1.161
BRENDA, the Enzyme Database: 2.7.1.161

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