KEGG   ENZYME: 2.7.1.172
Entry
EC 2.7.1.172                Enzyme                                 
Name
protein-ribulosamine 3-kinase;
Fn3KRP;
FN3K-related protein;
FN3K-RP;
ketosamine 3-kinase 2;
fructosamine-3-kinase-related protein;
ribulosamine/erythrulosamine 3-kinase;
ribulosamine 3-kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:[protein]-N6-D-ribulosyl-L-lysine 3-phosphotransferase
Reaction(IUBMB)
ATP + [protein]-N6-D-ribulosyl-L-lysine = ADP + [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine
Substrate
ATP [CPD:C00002];
[protein]-N6-D-ribulosyl-L-lysine
Product
ADP [CPD:C00008];
[protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine
Comment
This enzyme plays a role in freeing proteins from ribulosamines or psicosamines, which might arise from the reaction of amines with glucose and/or glycolytic intermediates. This role is shared by EC 2.7.1.171 (protein-fructosamine 3-kinase), which has, in addition, the unique capacity to phosphorylate fructosamines [1]. The plant enzyme also phosphorylates [protein]-N6-D-erythrulosyl-L-lysine [2]. No activity with [protein]-N6-D-fructosyl-L-lysine [1,2].
History
EC 2.7.1.172 created 2011
Orthology
K15523  protein-ribulosamine 3-kinase
Genes
HSA79672(FN3KRP)
PTR107969011(FN3KRP)
PPS100982920(FN3KRP)
PON100173348(FN3KRP)
NLE100598556(FN3KRP)
MCC716431(FN3KRP)
MCF101926623
MTHB126938940
CSAB103243781(FN3KRP)
CATY105588548(FN3KRP)
PANU101024062(FN3KRP)
TGE112610163(FN3KRP)
RRO104654998(FN3KRP)
RBB108534067(FN3KRP)
TFN117066395(FN3KRP)
PTEH111527652
CJC103793436(FN3KRP) 108590074
SBQ101053544(FN3KRP)
CSYR103253920(FN3KRP)
MMUR105878086(FN3KRP)
LCAT123620513
OGA100943845(FN3KRP)
MMU238024(Fn3krp)
MCAL110305073(Fn3krp)
MPAH110332262(Fn3krp)
RNO303755(Fn3krp)
MCOC116078162(Fn3krp)
MUN110548848(Fn3krp)
CGE100752057(Fn3krp)
MAUA101831042
PLEU114703923
MORG121444115 121444632
MFOT126493440
AAMP119813485
NGI103739319(Fn3krp)
HGL101709333(Fn3krp)
CPOC100718087(Fn3krp)
CCAN109689328(Fn3krp)
DORD105998447
DSP122122413
NCAR124981316
OCU100344530
OPI118759525
TUP102476157(FN3KRP)
GVR103602381(FN3KRP)
CFA480821(FN3KRP)
CLUD112672987
VVP112920927(FN3KRP)
VLG121473604
AML100464438(FN3KRP)
UMR103666018(FN3KRP)
UAH113244463(FN3KRP)
UAR123777937
ELK111160365
LLV125087470
MPUF101684879
ORO101368544(FN3KRP)
EJU114216206(FN3KRP)
ZCA113908062
MLX118024134(FN3KRP)
NSU110572450
LWW102740302
FCA101092971(FN3KRP)
PYU121018116
PBG122485998
LRUF124522539
PTG102972037(FN3KRP)
PPAD109276731(FN3KRP)
AJU106986345(FN3KRP)
HHV120228221
BTA615868(FN3KRP)
BOM102281298(FN3KRP)
BIU109574261(FN3KRP)
BBUB102407309
BBIS105000470(FN3KRP)
CHX102184372(FN3KRP)
OAS101108669
ODA120866908
CCAD122439288
SSC100523691(FN3KRP)
CFR102524558(FN3KRP)
CBAI105065526(FN3KRP)
CDK105102231(FN3KRP)
VPC102533388(FN3KRP)
BACU102998458(FN3K)
LVE103084046(FN3KRP)
OOR101282663(FN3KRP)
DLE111182656(FN3KRP)
PCAD102996441(FN3KRP)
PSIU116745709(FN3KRP)
ECB100056107(FN3KRP)
EPZ103562261
EAI106846292
MYB102243427(FN3KRP)
MYD102772995(FN3KRP)
MMYO118653124
MLF102422258(FN3KRP)
MNA107539086(FN3KRP)
PKL118704541
HAI109393079(FN3KRP)
DRO112298733(FN3KRP)
SHON118999252
AJM119058517
PDIC114503158
PHAS123817571
MMF118634349
RFQ117013657(FN3KRP)
PALE102898584(FN3KRP)
PGIG120600043
PVP105301117(FN3KRP)
RAY107504047(FN3KRP)
MJV108395009(FN3KRP)
TOD119230630
SARA101539210(FN3KRP)
LAV100670171(FN3KRP)
TMU101360659
ETF101643517
DNM101445149(FN3KRP)
MDO100020750(FN3KRP)
GAS123247975
SHR100913340
PCW110209249
OAA100079591
GGA417336(FN3KRP)
PCOC116232645
MGP100550464
CJO107322144(FN3KRP)
NMEL110407391
APLA101792751
ACYG106047110
AFUL116496533(FN3KRP)
TGU100190639(FN3KRP)
LSR110482531
SCAN103823225 103825435
PMOA120501794
OTC121335724 121338572
PRUF121351864
GFR102033081 102038597
FAB101811693 101814134
PHI102106402 102110282
PMAJ107198385
CCAE111941884
CCW104691972 104698008
CBRC103616465 103621801
ETL114063872
ZAB102074728
ACHL103808340
FPG101910739(FN3KRP)
FCH102060101
CLV102083608
EGZ104125362(FN3KRP)
NNI104022888(FN3KRP)
PLET104620944(FN3K) 104620945(FN3KRP)
PCRI104030811(FN3KRP) 104030812(FN3K)
PCAO104039620(FN3KRP) 104040146(FN3K)
ACUN113486920
TALA104368173
PADL103918759(FN3KRP)
AFOR103899041 103899042(FN3K)
ACHC115341852
HALD104318152(FN3KRP) 104318153(FN3K)
HLE104839227(FN3K) 104839228(FN3KRP)
AGEN126043827
GCL127023952 127024048
CCRI104154747 104155927(FN3K)
CSTI104560008
EHS104515615(FN3K) 104515616
CMAC104474291(FN3KRP)
MUI104536570 104536571(FN3K)
FGA104069632(FN3KRP)
GSTE104258364(FN3K) 104258365(FN3KRP)
LDI104344085(FN3K) 104344086(FN3KRP)
MNB103769623(FN3K) 103775611
OHA104334880(FN3K) 104334881(FN3KRP)
NNT104401570(FN3KRP) 104401572(FN3K)
DPUB104297997
PGUU104462356(FN3KRP)
ACAR104531123 104531124
CPEA104398185(FN3K) 104398197
AVIT104270910(FN3K)
CVF104289769(FN3KRP) 104289780(FN3K)
CUCA104059431(FN3K) 104059432(FN3KRP)
TEO104374199(FN3K) 104374200
BRHI104491424(FN3KRP) 104491425(FN3K)
AAM106499408
AROW112970846
NPD112957688(FN3KRP)
TGT104570975(FN3KRP) 104571856(FN3K)
DNE112995553(FN3KRP)
SCAM104143535(FN3KRP) 104143543(FN3K)
ASN102375382
AMJ102571809(FN3KRP)
CPOO109315144
GGN109287452
PSS102458928
CMY102934304
CPIC101941114
TST117887445(FN3KRP)
CABI116832196(FN3KRP)
MRV120384021
ACS100552114(fn3krp)
PVT110080441(FN3KRP)
SUND121920400
PBI103055928(FN3KRP)
PMUR107293620(FN3KRP)
CTIG120315325
TSR106541361(FN3KRP)
PGUT117659757(FN3KRP)
VKO123035594
PMUA114590765
ZVI118079941
GJA107121874(FN3KRP)
STOW125428260
XLA444726(fn3krp.S) 779262(fn3k.L)
XTR548561(fn3k) 779663(fn3krp)
NPR108784738 108784745
RTEM120919126
BBUF121005923 121005925
DRE559954(fn3krp)
SRX107744985
SANH107670452
SGH107599346
CCAR109064018
CAUA113051500
PPRM120489391 120489392
MAMB125263621
IPU108256901(fn3krp)
PHYP113546208
SMEO124376392
TFD113661963
AMEX103027201
EEE113587308
TRU101068065
TNGGSTEN00019740G001
LCO104918611
NCC104960327
CGOB115012190
ELY117268745 117268746
EFO125879719 125879721
PLEP121956283
SLUC116059360
ECRA117958724(fn3krp)
ESP116702425
PFLV114569265
GAT120827999
PPUG119220705
MSAM119890867
CUD121529275
ALAT119013961
MZE101487576
ONL100691075
OAU116317664
OLA101166386
OML112146776(fn3krp)
XMA102228035
XCO114159397
XHE116736232
PRET103468804
PFOR103140914
PLAI106946614
PMEI106925878
GAF122821702
CVG107100138
CTUL119794844
GMU124863063 124864562
NFU107378286
KMR108241277(fn3krp)
ALIM106529831
NWH119421028
AOCE111572146
MCEP124997721
CSEM103392706
POV109634196
SSEN122785766
HHIP117765908(fn3krp)
HSP118123064
LCF108902705(fn3krp)
SDU111227052
SLAL111653700
XGL120785802
HCQ109532519
BPEC110169419
MALB109965958 109965959
BSPL114861121
SASA106601911 106606261
STRU115171910 115208245
OTW112240563
OMY100305309(kt3k) 110538843
OGO124018256 124018260
SALP112079299 112079429
SNH120042305
CCLU121551490 121570001
ELS105006161 105006163
SFM108937375
PKI111852844
AANG118216859 118216860
LOC102686967
PSPA121296026
ARUT117424370(fn3krp)
PSEX120517530
LCM102361196(FN3KRP)
CMK103175706(fn3krp)
RTP109923269
BFO118425724 118425729
BBEL109466749
CIN100175560
SCLV120337118 120338246
SPU115918478 115928276 581319 585587 589710 589866
APLC110976653
AJC117124592
SKO100375988
BCOO119084703
API100168663
AGS114123511
RMD113553840
BTAB109032778
DCI103515483
CLEC106663775
HHAL106679963
NLU111050571
PHUPhum_PHUM156680
FOC113216112
TPAL117651615
ZNE110834669
CSEC111862813
SGRE126355659
FCD110858520
DPXDAPPUDRAFT_48121
DMK116935978
DPZ124311324
PVM113802613 113808041 113810868
PJA122248911 122255791 122256900 122258790
PCHN125046052 125046184 125046258
HAME121865441
PCLA123761087
PTRU123501781 123512242
HAZT108681577
LSM121118428
PPOI119104371 119108770
ISCIscW_ISCW019234
DSV119445913
RSAN119390333 119390339 119404544
RMP119172357
VDE111255171
VJA111262509
TUT107359867
DPTE113791631
DFR124495275
CSCU111623609
CELCELE_Y116A8C.25(Y116A8C.25)
CBRCBG_00429
BMYBM_BM7314(Bm7314)
LOALOAG_00692 LOAG_08641
NAINECAME_13926
LGILOTGIDRAFT_121864 LOTGIDRAFT_146827 LOTGIDRAFT_169246
BGT106063368
GAE121368535 121369515
HRF124137840
HRJ124290325
CRG105319389
MYI110450645
PMAX117332608 117332610
MMER123533656
LAK106151239
NVE5513059
EPA110241378
ATEN116288769
ADF107349801
AMIL114958169
PDAM113682898
SPIS111329315
TADTRIADDRAFT_28558
AQU100641712
ATHAT3G61080
ALY9314427
CRB17886329
CSAT104699801 104749232 104788386
EUSEUTSA_v10006098mg
BRP103830281
BNA106353257 106452595
BOE106298356
RSZ108817086 108817087
THJ104827683
CPAP110819567
CIT102623897
CICCICLE_v10021113mg
PVY116119586
MINC123222882
TCC18614223
GRA105802641
GHI107911946
GAB108471069
DZI111304671
EGR104443493
GMX100801047 100809481
GSJ114405804 114418501
PVUPHAVU_010G092700g
VRA106778982
VAR108347511
VUN114165933 114165934
CCAJ109796294
APRC113850482
MTR25500958
CAM101512368
PSAT127075864
LJALj0g3v0255569.2(Lj0g3v0255569.2)
ADU107475790
AIP107626071
AHF112728430 112755146
LANG109360592
FVE101296141
RCN112179984
PPER18785089
PMUM103331969
PAVI110769247
PDUL117620164
MDM103439144
PXB103935487
ZJU107432665
MNT21385862 21387224
CSV101207798
CMO103483312
BHJ120071419
MCHA111016237
CMAX111479743
CMOS111431796
CPEP111789914
RCU8258509
HBR110637026
MESC110615853
POP7461742
PEU105124925
PALZ118042277
JRE108980868
QSU112013134 112025373 112040410
QLO115958298
TWL119982698
VVI100252411
VRI117932167
SLY101263642
SPEN107008193
SOT102594708
SSTN125863117
CANN107872803
NTA107796842 107801652
NSY104230356
NTO104094265
NAU109205609
INI109156085
ITR115996648
SIND105171905
OEU111380162
EGT105963751
SSPL121784867
APAN127245678
ECAD122592633
LSV111912867
CCAV112526610
DCR108193270
CSIN114302549
BVG104905479
SOE110799577
CQI110685358 110714539
NNU104596179
MING122061309
TSS122666171
PSOM113297148
OSA4331411
DOSAOs03t0117800-01(Os03g0117800)
OBR102715375
BDI100846855
ATS109779410
TDC119292096 119298355 119304185
TAES123093821 123099049 123105995 123108275
TUA125527542
LPER127297362
SBI8077990
ZMA100277385
SITA101760144
SVS117836248
PVIR120647553
PHAI112875535
PDA103716861 120109013
EGU105043388 105054149
MUS103993209
ZOF122007964 122015922
PEQ110031088
AOF109838331
NCOL116260785
ATR18447760
SMOSELMODRAFT_270452 SELMODRAFT_272024
PPP112292648
CRECHLRE_12g542202v5
VCNVOLCADRAFT_66217
MNGMNEG_0014
CSLCOCSUDRAFT_32889
CVRCHLNCDRAFT_48255
APROF751_6551
OLUOSTLU_41216
OTAOT_ostta06g01890
BPGBathy05g01890
MISMICPUN_84028
MPPMICPUCDRAFT_51864
CCPCHC_T00000139001
NCRNCU09611
SMPSMAC_01539 SMAC_03865 SMAC_08907
PANPODANSg09281 PODANSg1002 PODANSg1280 PODANSg1587 PODANSg6911 PODANSg8662
TTTTHITE_123229 THITE_15754 THITE_2039488 THITE_2116464 THITE_2116537 THITE_2117702 THITE_2118142 THITE_2122990 THITE_2123863
MTMMYCTH_2057810 MYCTH_2311342 MYCTH_2312875
CTHRCTHT_0007490 CTHT_0047440
MGRMGG_08952 MGG_10482 MGG_11859 MGG_16231
PPEIPpBr36_07453
TMNUCRPA7_387 UCRPA7_910
SSCKSPSK_09552
FGRFGSG_09450 FGSG_10884
FPUFPSE_07547 FPSE_09821
FVRFVEG_11560
FOXFOXG_12818
NHENECHADRAFT_104325 NECHADRAFT_77174 NECHADRAFT_85528 NECHADRAFT_92087
TRETRIREDRAFT_5249
TRRM419DRAFT_132975
MAWMAC_03532 MAC_05043
MAJMAA_02655 MAA_03541 MAA_08470
PLJVFPFJ_01994 VFPFJ_06495 VFPFJ_06695
VALVDBG_00511 VDBG_04600 VDBG_04684 VDBG_05566
VDAVDAG_04150 VDAG_04225 VDAG_05750 VDAG_07508
CFJCFIO01_03865 CFIO01_08252 CFIO01_08736
CLUPCLUP02_01293
CHIGCH63R_10219
SAPOSAPIO_CDS0980 SAPIO_CDS4244 SAPIO_CDS6123 SAPIO_CDS6368
ELAUCREL1_11056 UCREL1_1480 UCREL1_4318 UCREL1_5282 UCREL1_7349 UCREL1_8920
PFYPFICI_02586 PFICI_12913 PFICI_13426 PFICI_14953
SSLSS1G_01634
BFUBCIN_02g02850
PSCOLY89DRAFT_659046 LY89DRAFT_684455
GLZGLAREA_02228 GLAREA_02376 GLAREA_05035 GLAREA_05669 GLAREA_07182 GLAREA_10427
ACTACLA_027530
NFINFIA_017660
AORAO090009000551 AO090012000956
ANGANI_1_210174(An10g00710) ANI_1_2260014(An01g01490)
APUUAPUU_20339S
PCSPc12g05550 Pc20g14050 Pc22g11640
PDPPDIP_25780
TMFPMAA_096310
CIMCIMG_02456 CIMG_08864 CIMG_09820
CPWCPC735_022660 CPC735_040800 CPC735_063790
UREUREG_06288 UREG_07237 UREG_07385
PBLPAAG_00089
PBNPADG_12252
ABEARB_02447 ARB_04185
TVETRV_06021 TRV_08039
AJEHCAG_03922
BGHBDBG_05694
PNOSNOG_00147
PTEPTT_15060
BZECOCCADRAFT_7259
BSCCOCSADRAFT_87109
BORCOCMIDRAFT_8839
AALTCC77DRAFT_1025553 CC77DRAFT_156698 CC77DRAFT_950732 CC77DRAFT_959862
ZTRMYCGRDRAFT_68030 MYCGRDRAFT_88477
PFJMYCFIDRAFT_30675
FFUCLAFUR5_04418 CLAFUR5_14231
BCOMBAUCODRAFT_31752
NPAUCRNP2_7245
TMLGSTUM_00002258001
CNBCNBE0140
CNGCNAG_02542
CGICGB_E0170C
TMSTREMEDRAFT_58482
TVSTRAVEDRAFT_111994 TRAVEDRAFT_41625
DSQDICSQDRAFT_95667
PCOPHACADRAFT_134866
SHSSTEHIDRAFT_117318
HIRHETIRDRAFT_305258
PSQPUNSTDRAFT_79940
ADLAURDEDRAFT_62885
FMEFOMMEDRAFT_89578
GTRGLOTRDRAFT_52535
CCICC1G_15844
ABPAGABI1DRAFT67377(AGABI1DRAFT_67377)
ABVAGABI2DRAFT196782(AGABI2DRAFT_196782)
MRRMoror_316
MOREE1B28_001418
SCMSCHCO_0241481(SCHCODRAFT_0241481)
CPUTCONPUDRAFT_116071
SLASERLADRAFT_455949
WSEWALSEDRAFT_70432
WICJ056_001259
UMAUMAG_10439
PFPPFL1_02221
SMINv1.2.031035.t1(symbB.v1.2.031035.t1)
AAFAURANDRAFT_27452
EHXEMIHUDRAFT_204773 EMIHUDRAFT_71649
GTTGUITHDRAFT_70468 GUITHDRAFT_76935
HJABST95_04925
HALCEY643_17325
MDNJT25_018740
METLU737_09595
MEJQ7A_2653
MECQ7C_1098
HHCM911_15410
OMEOLMES_0888
RMARmag_0948
NEUNE1855
NITNAL212_1856
NIINit79A3_2092
NURATY38_14530
NSTNstercoris_02093
NMUNmul_A2329
MAESGa0123461_1130
MFNGa0123462_1223
MFFMFFC18_19560
ROLCA51_22750
TPXTurpa_3077
PBTING2E5B_2231
PMUCING2E5A_0244
PETPEIBARAKI_4068
PSACPSM36_0061
ALDGFH31_01240
DORIFH5T_18535
DRCG0Q07_10790
MCOSGM418_26715
ASXCDL62_13175
MBASALGA_4018
EVIEchvi_1828
ESTDN752_15135
ECHIFKX85_08915
SLISlin_5692
SMONAWR27_24080
SPIRCWM47_15420
SPIKEXU85_01415
PSEZHME7025_02331
RHOZGXP67_21900
RSIRunsl_5550
RUNDR864_25915
EOLEmtol_1614
MTTFtrac_0034
FPFDCC35_06330
FLMMY04_2407
FBTD770_07970
CHKD4L85_09075
RBIRB2501_06940
FBCFB2170_06060
MARBCJ263_08445
ZGAZOBELLIA_1687
MLTVC82_2651
SEONBWZ22_11050
FEKC1H87_19540
EMARD1013_00925
IALIALB_1886
 » show all
Reference
1  [PMID:14633848]
  Authors
Collard F, Delpierre G, Stroobant V, Matthijs G, Van Schaftingen E
  Title
A mammalian protein homologous to fructosamine-3-kinase is a ketosamine-3-kinase acting on psicosamines and ribulosamines but not on fructosamines.
  Journal
Diabetes 52:2888-95 (2003)
DOI:10.2337/diabetes.52.12.2888
  Sequence
[hsa:79672] [mmu:238024]
Reference
2  [PMID:15705060]
  Authors
Fortpied J, Gemayel R, Stroobant V, van Schaftingen E
  Title
Plant ribulosamine/erythrulosamine 3-kinase, a putative protein-repair enzyme.
  Journal
Biochem J 388:795-802 (2005)
DOI:10.1042/BJ20041976
  Sequence
[ath:AT3G61080] [osa:4331411]
Reference
3  [PMID:18637789]
  Authors
Payne LS, Brown PM, Middleditch M, Baker E, Cooper GJ, Loomes KM
  Title
Mapping of the ATP-binding domain of human fructosamine 3-kinase-related protein  by affinity labelling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
  Journal
Biochem J 416:281-8 (2008)
DOI:10.1042/BJ20080389
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.172
IUBMB Enzyme Nomenclature: 2.7.1.172
ExPASy - ENZYME nomenclature database: 2.7.1.172
BRENDA, the Enzyme Database: 2.7.1.172

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