KEGG   ENZYME: 2.7.1.197
Entry
EC 2.7.1.197                Enzyme                                 

Name
protein-Npi-phosphohistidine---D-mannitol phosphotransferase;
mtlA (gene name);
D-mannitol PTS permease;
EIIMtl
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
protein-Npi-phospho-L-histidine:D-mannitol Npi-phosphotransferase
Reaction(IUBMB)
[protein]-Npi-phospho-L-histidine + D-mannitol[side 1] = [protein]-L-histidine + D-mannitol 1-phosphate[side 2] [RN:R02704]
Reaction(KEGG)
R02704
Substrate
[protein]-Npi-phospho-L-histidine [CPD:C04261];
D-mannitol[side 1] [CPD:C00392]
Product
[protein]-L-histidine [CPD:C00615];
D-mannitol 1-phosphate[side 2] [CPD:C00644]
Comment
This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
History
EC 2.7.1.197 created 1972 as EC 2.7.1.69, part transferred 2016 to EC 2.7.1.197
Pathway
ec00051  Fructose and mannose metabolism
ec01100  Metabolic pathways
Orthology
K02798  mannitol PTS system EIIA component
K02800  mannitol PTS system EIICBA or EIICB component
Genes
AALB: 115261091
ECO: b2933(cmtA) b2934(cmtB) b3599(mtlA)
ECJ: JW2900(cmtA) JW2901(cmtB) JW3573(mtlA)
ECD: ECDH10B_3780(mtlA)
EBW: BWG_2655(cmtA) BWG_2656(cmtB) BWG_3289(mtlA)
ECOK: ECMDS42_2432(cmtA) ECMDS42_2433(cmtB) ECMDS42_3032(mtlA)
ECE: Z4277(cmtA) Z4278(cmtB) Z5023(mtlA)
ECS: ECs3808 ECs3809(cmtB) ECs4475
ECF: ECH74115_4234 ECH74115_4235(cmtB) ECH74115_4969(mtlA)
ETW: ECSP_3903(cmtA) ECSP_3904(cmtB) ECSP_4592(mtlA)
EOI: ECO111_3673(cmtA) ECO111_3674(cmtB) ECO111_4420(mtlA)
EOJ: ECO26_4024(cmtA) ECO26_4025(cmtB) ECO26_5001(mtlA)
EOH: ECO103_3512(cmtA) ECO103_3513(cmtB) ECO103_4583(mtlA)
ECK: EC55989_3225(cmtA) EC55989_3226(cmtB) EC55989_4063(mtlA)
ECG: E2348C_3184(cmtA) E2348C_3185(cmtB) E2348C_3845(mtlA)
EOK: G2583_3591(cmtA) G2583_3592(cmtB) G2583_4335(mtlA)
ENA: ECNA114_2977(cmtA) ECNA114_2978(cmtB) ECNA114_3748(mtlA)
ECOS: EC958_3216(cmtA) EC958_3217(cmtB) EC958_4003(mtlA)
ECV: APECO1_2858(mtlA) APECO1_3596(cmtB) APECO1_3597(cmtA)
ECM: EcSMS35_3075(cmtB) EcSMS35_3932(mtlA)
ECR: ECIAI1_3058(cmtA) ECIAI1_3059(cmtB) ECIAI1_3769(mtlA)
ECQ: ECED1_3394(cmtA) ECED1_3395(cmtB) ECED1_4281(mtlA)
EUM: ECUMN_3282(cmtA) ECUMN_3283(cmtB) ECUMN_4110(mtlA)
ECT: ECIAI39_3351(cmtA) ECIAI39_3352(cmtB) ECIAI39_4114(mtlA)
EOC: CE10_3373(cmtA) CE10_3374(cmtB) CE10_4155(mtlA)
EBR: ECB_02763(cmtA) ECB_02764(cmtB) ECB_03454(mtlA)
EBL: ECD_02763(cmtA) ECD_02764(cmtB) ECD_03454(mtlA)
EBE: B21_02726(cmtA) B21_02727(cmtB) B21_03405(mtlA)
ECI: UTI89_C3320(cmtA) UTI89_C3321(cmtB) UTI89_C4137(mtlA)
EIH: ECOK1_3320(cmtA) ECOK1_3321(cmtB) ECOK1_4040(mtlA)
ECZ: ECS88_3214(cmtA) ECS88_3215(cmtB) ECS88_4012(mtlA)
ECC: c3515(cmtA) c3516(cmtB) c4416(mtlA)
ELO: EC042_3141(cmtA) EC042_3142(cmtB) EC042_3906(mtlA)
EKF: KO11_04705(mtlA) KO11_08080(cmtB) KO11_08085(cmtA)
EAB: ECABU_c32170(cmtA) ECABU_c32180(cmtB) ECABU_c40360(mtlA)
ELW: ECW_m3192(cmtA) ECW_m3193(cmtB) ECW_m3875(mtlA)
ELL: WFL_15585(cmtA) WFL_15590(cmtB) WFL_18935(mtlA)
ELC: i14_3236(cmtA) i14_3237(cmtB) i14_4081(mtlA)
ELD: i02_3236(cmtA) i02_3237(cmtB) i02_4081(mtlA)
ELP: P12B_c3025(cmtA) P12B_c3026(cmtB) P12B_c3728(mtlA)
ELF: LF82_0327(cmtA) LF82_0328(cmtB) LF82_1406(mtlA)
ECOI: ECOPMV1_03206(mtlA_1) ECOPMV1_03207(cmtB) ECOPMV1_03931(mtlA_2)
EFE: EFER_2864(cmtA) EFER_2865(cmtB) EFER_3590(mtlA)
STY: STY4111(mtlA)
STT: t3834(mtlA)
STM: STM3685(mtlA)
SEO: STM14_4443(mtlA)
SEY: SL1344_3650(mtlA)
SEJ: STMUK_3671(mtlA)
SEB: STM474_3857(mtlA)
SEF: UMN798_4003(mtlA)
SENR: STMDT2_35691(mtlA)
SEND: DT104_36681(mtlA)
SENI: CY43_19125
SPT: SPA3536(mtlA)
SEK: SSPA3302
SEI: SPC_3765(mtlA)
SEC: SCH_3609(mtlA)
SHB: SU5_04162
SENS: Q786_18015
SED: SeD_A4070
SEG: SG3745(mtlA)
SEL: SPUL_3880(mtlA)
SEGA: SPUCDC_3866(mtlA)
SET: SEN3507(mtlA)
SENA: AU38_17915
SENO: AU37_18105
SENV: AU39_18110
SENQ: AU40_20175
SENL: IY59_18550
SEEP: I137_18615
SENE: IA1_17910
SFL: SF3633(mtlA)
SFX: S4135(mtlA)
SFV: SFV_3938(mtlA)
SFE: SFxv_3960(mtlA)
SFS: SFyv_5252
SFT: NCTC1_03929(mtlA)
SSN: SSON_3088(cmtB) SSON_3809(mtlA)
SBO: SBO_3055(cmtB) SBO_3056(cmtA) SBO_3597(mtlA)
SBC: SbBS512_E3365(cmtA) SbBS512_E3366(cmtB) SbBS512_E4016(mtlA)
SDY: SDY_3143(cmtB) SDY_3144(cmtA)
ENC: ECL_00170
ECLX: LI66_21965
ECLY: LI62_23990
ECLZ: LI64_21045
EEC: EcWSU1_00141(mtlA)
ESA: ESA_03877
CSK: ES15_3790(mtlA)
CTU: CTU_01290(mtlA)
KPN: KPN_03942(mtlA)
KPU: KP1_2729 KP1_5289(mtlA)
KPR: KPR_2582 KPR_4972(mtlA)
KPX: PMK1_01446(mtlA) PMK1_04013(fruB_2)
KPNK: BN49_0169(mtlA) BN49_2790
KPE: KPK_0153(mtlA) KPK_2687 KPK_B0039(cmtA)
EAE: EAE_06200
EAR: CCG32762
CRO: ROD_42221(mtlA)
RTG: NCTC13098_00173(mtlA_1) NCTC13098_00174(mtlA_2)
REE: electrica_00147(mtlA) electrica_02729(fruB_2)
CLAP: NCTC11466_00055(mtlA_1)
KIE: NCTC12125_02217(mtlA_1) NCTC12125_02218(mtlA_2)
EBF: D782_0125
PSTS: E05_31930
YPE: YPO4068(mtlA)
YPK: y4087(mtlA)
YPH: YPC_4588(mtlA)
YPA: YPA_3014
YPN: YPN_3715
YPM: YP_3979(mtlA)
YPG: YpAngola_A3780(mtlA)
YPZ: YPZ3_3490(mtlA)
YPX: YPD8_3588
YPW: CH59_2026(mtlA)
YPJ: CH55_2751(mtlA)
YPV: BZ15_3633(mtlA)
YPL: CH46_981(mtlA)
YPS: YPTB3918(mtlA)
YPO: BZ17_2663(mtlA)
YPI: YpsIP31758_4128(mtlA)
YPY: YPK_0026
YPB: YPTS_4138
YPQ: DJ40_2488(mtlA)
YPU: BZ21_3275(mtlA)
YPR: BZ20_2185(mtlA)
YPC: BZ23_3552(mtlA)
YPF: BZ19_3389(mtlA)
YEN: YE4148(mtlA)
YEW: CH47_3581(mtlA)
YET: CH48_1609(mtlA) CH48_3241
YEE: YE5303_40021(mtlA)
YAL: AT01_2542(mtlA) AT01_32
YFR: AW19_3321(mtlA)
YIN: CH53_1693(mtlA) CH53_3459
YKR: CH54_2469(mtlA)
YRO: CH64_2526(mtlA)
YRU: BD65_2042(mtlA)
SMAR: SM39_4414(mtlA)
SMAC: SMDB11_4180(mtlA)
SMW: SMWW4_v1c00600(mtlA)
SPE: Spro_0072
SRL: SOD_c00320(mtlA)
SPLY: Q5A_000155(mtlA)
SMAF: D781_0027
SERF: L085_04740
SFJ: SAMEA4384070_0039(mtlA)
SOF: NCTC11214_01792(mtlA_1)
RAA: Q7S_00160
ECA: ECA0087(mtlA)
PATR: EV46_00450
PATO: GZ59_00930(mtlA)
PCT: PC1_4165
PEC: W5S_4625
SGL: SG0014
SOD: Sant_0099(mtlA)
DDD: Dda3937_00995(mtlA)
DDQ: DDI_4368
EAM: EAMY_3640(mtlA)
EAY: EAM_3416(mtlA)
ETA: ETA_34180(mtlA)
EPY: EpC_36330(mtlA)
EPR: EPYR_03914(mtlA)
EBI: EbC_11370 EbC_45220(mtlA)
ERJ: EJP617_11070(mtlA)
EGE: EM595_3389(mtlA)
BUC: BU572(mtlA)
BAP: BUAP5A_565(mtlA)
BAU: BUAPTUC7_566(mtlA)
BAJC: CWS_02940
BUA: CWO_02995
BUP: CWQ_03035
BAK: BAKON_580(mtlA)
BUH: BUAMB_545(mtlA)
BAPF: BUMPF009_CDS00033(mtla)
BAPG: BUMPG002_CDS00033(mtla)
BAPU: BUMPUSDA_CDS00033(mtla)
BAPW: BUMPW106_CDS00033(mtla)
BAS: BUsg_552(mtlA)
BAB: bbp_517(mtlA)
BAPH: IX46_02950
PAM: PANA_0112(mtlA)
PLF: PANA5342_4316(mtlA)
PAJ: PAJ_3274(mtlA)
PVA: Pvag_3337(mtlA)
PSTW: DSJ_22385
MINT: C7M51_03650(mtlA)
MTHI: C7M52_03383(mtlA)
PRG: RB151_027370(mtlA) RB151_031050(fruB_2)
PHEI: NCTC12003_01190(fruB_2)
ETE: ETEE_1793(mtlA)
HSO: HS_1252(mtlA)
HSM: HSM_0825
PMU: PM1061(ptmA)
PMV: PMCN06_0167(mtlA)
PMP: Pmu_00950(mtlA)
PMUL: DR93_904(mtlA)
MSU: MS0411(mtlA)
MHT: D648_1270
MHAT: B824_360
MHX: MHH_c06610(mtlA)
MHAE: F382_07520
MHAM: J450_07525
MHAO: J451_08450
MHAL: N220_00565
MHAQ: WC39_13500
MHAY: VK67_13505
MVR: X781_630
MVI: X808_780
MVG: X874_750
APL: APL_1630(mtlA)
APJ: APJL_1663(mtlA)
APA: APP7_1692(mtlA)
ASU: Asuc_0455
AAT: D11S_1816
AAN: D7S_00601
AACN: AANUM_1307
BTO: WQG_2860
BTRE: F542_19100
BTRH: F543_20980
BTRA: F544_3270
AVT: NCTC3438_00631(mtlA)
VCH: VCA1045
VCS: MS6_A1075
VCI: O3Y_18378
VCO: VC0395_0196(mtlA)
VCR: VC395_A1068(mtlA)
VCM: VCM66_A1003(mtlA)
VCX: VAA049_1959(mtlA)
VCZ: VAB027_1089(mtlA)
VVU: VV1_0638
VVY: VV0505
VAG: N646_2555
VAN: VAA_02789
VAU: VANGNB10_cII0028(mtlA)
VFI: VF_A0060(cmtB) VF_A0061(cmtA)
VSA: VSAL_I2813(mtlA)
AWD: AWOD_I_0243(mtlA)
PPR: PBPRB0363(C4416)
AHA: AHA_0551
ASA: ASA_3757(mtlA)
AVR: B565_0504
AMED: B224_4811
ACAV: VI35_18780
AEL: NCTC12917_00453(mtlA)
TAU: Tola_0283
CHJ: NCTC10426_01793(mtlA)
DAT: HRM2_08670(mtp)
BSU: BSU03981(mtlA) BSU03982(mtlF)
BSL: A7A1_3080
BSH: BSU6051_03981(mtlA) BSU6051_03982(mtlF)
BSUT: BSUB_00449(mtlA) BSUB_00450(mtlF)
BSUL: BSUA_00449(mtlA) BSUA_00450(mtlF)
BSS: BSUW23_02055(mtlA) BSUW23_02060(mtlF)
BSQ: B657_03981(mtlA) B657_03982(mtlF)
BSX: C663_0391(mtlA) C663_0392(mtlF)
BLD: BLi00505(mtlA) BLi00506(mtlF)
BLH: BaLi_c05260(mtlA) BaLi_c05270(mtlF)
BAQ: BACAU_0359(mtlA) BACAU_0360(mtlF)
BYA: BANAU_0359(mtlA) BANAU_0360(mtlF)
BAML: BAM5036_0382(mtlA) BAM5036_0383(mtlF)
BAMA: RBAU_0396(mtlA) RBAU_0397(mtlF)
BAMN: BASU_0381(mtlA) BASU_0382(mtlF)
BAMB: BAPNAU_0364(mtlA) BAPNAU_0365(mtlA1)
BAMY: V529_03840(mtlA) V529_03850
BMP: NG74_00400(mtlA) NG74_00401(mtlF)
BAO: BAMF_0366(mtlA1) BAMF_0367(mtlA2)
BAZ: BAMTA208_01855(mtlA1) BAMTA208_01860(mtlA2)
BQL: LL3_00382(mtlA) LL3_00383(mtlA)
BQY: MUS_0387(mtlA) MUS_0388(mtlA1)
BPF: BpOF4_05140(mtlA) BpOF4_05150(mtlA2)
BMQ: BMQ_0202
BMD: BMD_0196
BMH: BMWSH_5031(mtlA)
BMEG: BG04_2474(mtlA)
BMET: BMMGA3_01060(mtlA) BMMGA3_01070(mtlF)
BACL: BS34A_04560(mtlA) BS34A_04570(mtlF)
BEO: BEH_01295
BKW: BkAM31D_01160(mtlA) BkAM31D_01175(mtlF)
BBEV: BBEV_0377 BBEV_2198(sgcA) BBEV_2199(cmtA) BBEV_2947(mtlA) BBEV_2949(mtlF)
GGH: GHH_c20170(mtlF) GHH_c20190(mtlA)
GEA: GARCT_01926(mtlF)
AFL: Aflv_1563(mtlA) Aflv_1566(mtlA)
ANM: GFC28_383 GFC28_393(mtlA) GFC28_395(mtlF)
AAMY: GFC30_1707(mtlA) GFC30_1709(mtlF)
ANL: GFC29_1229(mtlF) GFC29_1231(mtlA) GFC29_1241
SAU: SA1960(mtlF) SA1962(mtlA)
SAV: SAV2156(mtlF) SAV2158(mtlA)
SAW: SAHV_2140(mtlF) SAHV_2142(mtlA)
SAM: MW2082(mtlF) MW2084(mtlA)
SAR: SAR2244(mtlA) SAR2246(mtlF)
SAX: USA300HOU_2146(mtlF) USA300HOU_2148(mtlA)
SAA: SAUSA300_2105(mtlF) SAUSA300_2107(mtlA)
SAE: NWMN_2057(mtlF) NWMN_2059(mtlA)
SUJ: SAA6159_02065(mtlA) SAA6159_02067(mtlA_1)
SUK: SAA6008_02192(mtlA) SAA6008_02194(mtlA_1)
SUZ: MS7_2171(mtlA) MS7_2173(mtlF)
SUW: SATW20_22910(mtlA) SATW20_22930(mtlF)
SAUE: RSAU_001992(mtlF) RSAU_001994(mtlA)
SAUZ: SAZ172_2257(mtlA) SAZ172_2259(mtlF)
SAUT: SAI1T1_2015920(mtlA)
SAUJ: SAI2T2_1015930(mtlA)
SAUK: SAI3T3_1015920(mtlA)
SAUQ: SAI4T8_1015930(mtlA)
SAUV: SAI7S6_1015930(mtlA)
SAUW: SAI5S5_1015870(mtlA)
SAUX: SAI6T6_1015880(mtlA)
SAUY: SAI8T7_1015910(mtlA)
SAB: SAB2036(mtlA) SAB2038(mtlF)
SUY: SA2981_2095(mtlF) SA2981_2097(mtlA)
SAUB: C248_2184(mtlA) C248_2186(mtlF)
SAUC: CA347_2231(mtlA) CA347_2233(mtlF)
SAUR: SABB_02477(mtlA) SABB_02479(mtlF)
SHA: SH0233(mtlA) SH0235(mtlF)
SHH: ShL2_00153(mtlA)
SCA: SCA_1658(mtlA) SCA_1660(mtlF)
SXO: SXYL_00774(mtlF) SXYL_00776(mtlA)
SCAP: AYP1020_1341(mtlA) AYP1020_1343(mtlF)
MCAK: MCCS_05040(mtlF) MCCS_05060(mtlA)
LMOG: BN389_27740(sgcA) BN389_27760(mtlA)
LMQ: LMM7_2914(cmtB) LMM7_2916(mtlA)
PPM: PPSC2_18835(mtlA1) PPSC2_18845(mtlA3)
PPO: PPM_3788(mtlA1) PPM_3790(mtlA3)
PMW: B2K_01480
PLV: ERIC2_c37400(mtlF) ERIC2_c37420(mtlA)
PRI: PRIO_1855(mtlA) PRIO_1857
AAD: TC41_0288(mtlA) TC41_0291(mtlA)
LLA: L32907(mtlF)
LLK: LLKF_0023(mtlA) LLKF_0025(mtlF)
LLT: CVCAS_0023(mtlA) CVCAS_0025(mtlF)
LLS: lilo_0021(mtlA) lilo_0023(mtlF)
LLX: NCDO2118_0023(mtlA) NCDO2118_0025(mtlF)
LLM: llmg_0022(mtlA) llmg_0024(mtlF)
LLI: uc509_0020(mtlA) uc509_0024(mtlF)
LLJ: LG36_0022(mtlA) LG36_0024(mtlF)
LPK: LACPI_1901(mtlF) LACPI_1903(mtlA)
SPN: SP_0394 SP_0396(mtlF)
SPD: SPD_0360(mtlA) SPD_0362(mtlA2)
SPR: spr0356(mtlA) spr0358(mtlF)
SPW: SPCG_0394(mtlA) SPCG_0396(mtlF)
SNE: SPN23F03700(mtlA) SPN23F03720(mtlF)
SNI: INV104_03390(mtlA) INV104_03410(mtlF)
SMU: SMU_1183(mtlA2) SMU_1185(mtlA1)
SMC: SmuNN2025_0860(mtlA1) SmuNN2025_0862(mtlA2)
SMJ: SMULJ23_0859(mtlA1) SMULJ23_0861(mtlA2)
SUB: SUB0288 SUB0289 SUB0995(mtlF) SUB0997(mtlA)
SGT: SGGB_0982(mtlA) SGGB_0984(mtlF)
STK: STP_0827(mtlF) STP_0829(mtlA)
LPL: lp_0230(pts2CB) lp_0232(pts2A)
LPJ: JDM1_0214(pts2CB) JDM1_0216(pts2A)
LPT: zj316_0433(pts2CB) zj316_0435(pts2A)
LPS: LPST_C0187 LPST_C0189(pts2A)
LSL: LSL_1619 LSL_1620(mtlA)
LSI: HN6_01360(mtlA)
LSJ: LSJ_1675c LSJ_1676c(mtlA)
LCB: LCABL_04510(mtlA) LCABL_31040(pts2A) LCABL_31060(pts2CB)
LCW: BN194_04580(mtlA) BN194_30410(mtlF) BN194_30430(mtlA_2)
LRH: LGG_02732(cmtB) LGG_02910(mtlF) LGG_02912(mtlA)
LRL: LC705_02736(pts) LC705_02874(mtlF) LC705_02876(mtlA)
LRA: LRHK_2847 LRHK_2993(mtlF) LRHK_2995(mtlA)
LCR: LCRIS_00467(mtlA) LCRIS_00468(mtlF)
PCE: PECL_457(mtlA) PECL_459(mtlF)
EFI: OG1RF_10292(mtlA) OG1RF_10294(mltF) OG1RF_10296(mtlA2) OG1RF_10297(mltF2)
EFN: DENG_00393(mtlA) DENG_00395(mtlA) DENG_00397(mtlA) DENG_00398(mtlA)
EMU: EMQU_2366(mltF) EMQU_2367(mtlA) EMQU_2378(mtlF) EMQU_2380
THL: TEH_03300(mtlA) TEH_03320(mtlF)
CRN: CAR_c14200(mtlF1) CAR_c14220(mtlA1) CAR_c20720(mtlF2) CAR_c20740(mtlA2)
CML: BN424_1810(mtlF) BN424_1812(mtlA) BN424_255(mtlA)
CAC: CA_C0154(MtlA) CA_C0156(MltF)
CAE: SMB_G0156(mtlA) SMB_G0158(mltF)
CAY: CEA_G0157(mtlA) CEA_G0159(mltF)
CSR: Cspa_c21480(mtlA) Cspa_c21510(mtlF)
CPAT: CLPA_c28820(mtlF) CLPA_c28840(mtlA)
CPAE: CPAST_c28820(mtlF) CPAST_c28840(mtlA)
ASF: SFBM_0209
FPA: FPR_09640
CDF: CD630_23320(mtlF) CD630_23340(mtlA)
PDC: CDIF630_02571(mtlF) CDIF630_02573(mtlA)
CDC: CD196_2175(mtlF) CD196_2177(mtlA)
CDL: CDR20291_2221(mtlF) CDR20291_2223(mtlA)
PHX: KGNDJEFE_01371(mtlF) KGNDJEFE_01372(mtlA_1) KGNDJEFE_01394(mtlA_2)
ELM: ELI_0427
TTE: TTE0339(MtlA) TTE0341(PtsN2)
TKI: TKV_c02830(mtlA) TKV_c02850(mtlF)
SRI: SELR_21630(mtlA)
STED: SPTER_39850(mtlF) SPTER_39860(mtlA)
ERH: ERH_0722(ulaC)
EUC: EC1_19350
ABSI: A9CBEGH2_07370(mtlA)
MPN: MPN651(mtlA) MPN653(mtlF)
MPM: MPNA6510(mtlA) MPNA6530(mtlF)
MPJ: MPNE_0761
MPU: MYPU_7510(MYPU_7510)
MMY: MSC_0019(EIIA-mtl) MSC_0021(EIIBC-mtl)
MML: MLC_0180(mtlF) MLC_0200(mtlA)
MCAC: MCCP01_0034(mtlF)
MCAP: MCCPF38_00031(mtlA_1) MCCPF38_00034(mtlF_1) MCCPF38_00549(mtlA_3) MCCPF38_00550(mtlF_2)
MHY: mhp567(mtlF) mhp569(mtlA)
MHJ: MHJ_0552(mtlF) MHJ_0554(mtlA)
MHP: MHP7448_0548(mtlF) MHP7448_0550(mtlA)
MHYO: MHL_2853(mtlF) MHL_2978(mtlA)
MCO: MCJ_006400(mtlF) MCJ_006420(mtlA)
MHR: MHR_0169(mtlF)
MHH: MYM_0181(mtlF)
MHV: Q453_0193(mtlF)
MFQ: MYF_02635(mtlF) MYF_02645(mtlA)
MYT: MYE_02580(mtlF) MYE_02585(mtlA)
SAPI: SAPIS_v1c01410(mtlA2)
SSAB: SSABA_v1c08620(mtlA2)
STUR: STURON_00775(mtlA2)
SCOU: SCORR_v1c07170(mtlA)
STAB: STABA_v1c09860(cmtA) STABA_v1c09870(cmtB)
SALX: SALLE_v1c02680(cmtA)
MVA: Mvan_5589
MGI: Mflv_1219
MVQ: MYVA_5508
LXX: Lxx00810 Lxx00820(EIIBC-Mtl)
CMI: CMM_1754 CMM_2590(mtlF) CMM_2591(mtlA)
CMS: CMS0309(mtlA) CMS0310(mtlF) CMS1998(fruB)
CMC: CMN_01734 CMN_02546(mtlA) CMN_02547(mtlB)
MTS: MTES_0611 MTES_0612(mtlD)
MOO: BWL13_02229(mtlA) BWL13_02230(mtlF)
MLV: CVS47_00712(mtlF) CVS47_00713(mtlA)
ART: Arth_4004
ARR: ARUE_c40020(mtlA)
ARX: ARZXY2_4236(mtlA)
AAU: AAur_3859(mtlA)
ACH: Achl_3789
PAC: PPA0919
PAK: HMPREF0675_3978(cmtA)
PAW: PAZ_c09560(mtlA)
PACC: PAC1_04855
CACN: RN83_04955
PAUS: NCTC13651_02535(mtlA)
ACIJ: JS278_01920(mtlA)
NCA: Noca_3164
NDK: I601_4067(mtlA)
MGG: MPLG2_2331(mtlA)
NDA: Ndas_4224
MMAR: MODMU_5314(mtlA)
AMYY: YIM_10425(mtlA1) YIM_10435(fruB)
ASE: ACPL_6370(fruB) ACPL_6372(mtlA)
ACTN: L083_0664(mtlA) L083_0666
DGO: DGo_CA2629(mtlA)
BRM: Bmur_2750
BPJ: B2904_orf2447(ptmCB)
BIP: Bint_0482
AFD: Alfi_3072
AOK: A3BBH6_27310(mtlA)
 » show all
Reference
1  [PMID:368051]
  Authors
Jacobson GR, Lee CA, Saier MH Jr
  Title
Purification of the mannitol-specific enzyme II of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system.
  Journal
J Biol Chem 254:249-52 (1979)
Reference
2  [PMID:6427236]
  Authors
Jacobson GR, Tanney LE, Kelly DM, Palman KB, Corn SB
  Title
Substrate and phospholipid specificity of the purified mannitol permease of Escherichia coli.
  Journal
J Cell Biochem 23:231-40 (1983)
DOI:10.1002/jcb.240230120
Reference
3  [PMID:6309813]
  Authors
Lee CA, Saier MH Jr
  Title
Mannitol-specific enzyme II of the bacterial phosphotransferase system. III. The  nucleotide sequence of the permease gene.
  Journal
J Biol Chem 258:10761-7 (1983)
  Sequence
[eco:b3599]
Reference
4  [PMID:2123863]
  Authors
Elferink MG, Driessen AJ, Robillard GT
  Title
Functional reconstitution of the purified phosphoenolpyruvate-dependent mannitol-specific transport system of Escherichia coli in phospholipid vesicles:  coupling between transport and phosphorylation.
  Journal
J Bacteriol 172:7119-25 (1990)
DOI:10.1128/JB.172.12.7119-7125.1990
Reference
5  [PMID:1909895]
  Authors
van Weeghel RP, Meyer G, Pas HH, Keck W, Robillard GT
  Title
Cytoplasmic phosphorylating domain of the mannitol-specific transport protein of  the phosphoenolpyruvate-dependent phosphotransferase system in Escherichia coli:  overexpression, purification, and functional complementation with the mannitol binding domain.
  Journal
Biochemistry 30:9478-85 (1991)
DOI:10.1021/bi00103a013
Reference
6  [PMID:8841134]
  Authors
Boer H, ten Hoeve-Duurkens RH, Robillard GT
  Title
Relation between the oligomerization state and the transport and phosphorylation  function of the Escherichia coli mannitol transport protein: interaction between  mannitol-specific enzyme II monomers studied by complementation of inactive site-directed mutants.
  Journal
Biochemistry 35:12901-8 (1996)
DOI:10.1021/bi9611016
  Sequence
[eco:b3599]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.197
IUBMB Enzyme Nomenclature: 2.7.1.197
ExPASy - ENZYME nomenclature database: 2.7.1.197
BRENDA, the Enzyme Database: 2.7.1.197

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