EC                Enzyme                                 

protein-Npi-phosphohistidine---galactitol phosphotransferase;
gatABC (gene names);
galactitol PTS permease;
Enzyme IIGat
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
protein-Npi-phospho-L-histidine:galactitol Npi-phosphotransferase
[protein]-Npi-phospho-L-histidine + galactitol[side 1] = [protein]-L-histidine + galactitol 1-phosphate[side 2] [RN:R05570]
[protein]-Npi-phospho-L-histidine [CPD:C04261];
galactitol[side 1] [CPD:C01697]
[protein]-L-histidine [CPD:C00615];
galactitol 1-phosphate[side 2] [CPD:C06311]
This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
EC created 1972 as EC, part transferred 2016 to EC
ec00052  Galactose metabolism
ec01100  Metabolic pathways
K02773  galactitol PTS system EIIA component
K02774  galactitol PTS system EIIB component
ECO: b2093(gatB) b2094(gatA) b4302(sgcA) b4565(sgcB)
ECJ: JW2077(gatB) JW2078(gatA) JW4264(sgcA) JW5967(sgcB)
ECD: ECDH10B_2246(gatB) ECDH10B_2247(gatA) ECDH10B_4503(sgcA) ECDH10B_4506(sgcB)
EBW: BWG_1879(gatB) BWG_1880(gatA) BWG_3999(sgcA) BWG_4002(sgcB)
ECE: Z3256(gatB) Z3257(gatA) Z4875 Z4876
ECS: ECs2896 ECs2897 ECs4350 ECs4351
ECF: ECH74115_3072(gatB) ECH74115_3073(gatA) ECH74115_4823 ECH74115_4824
ETW: ECSP_2888(gatB) ECSP_2889(gatA) ECSP_4457 ECSP_4458
ELX: CDCO157_2673 CDCO157_2674 CDCO157_4087 CDCO157_4088
EOI: ECO111_2809(gatB) ECO111_2810(gatA)
EOJ: ECO26_3002(gatB) ECO26_3003(gatA)
ECK: EC55989_2347(gatB) EC55989_2348(gatA)
ECG: E2348C_2238(gatB) E2348C_2239(gatA)
ECW: EcE24377A_2381(gatB) EcE24377A_2382(gatA)
ECX: EcHS_A2229(gatB) EcHS_A2230(gatA)
ECR: ECIAI1_2167(gatB) ECIAI1_2168(gatA)
EBR: ECB_02019(gatB) ECB_02020(gatA) ECB_04167(sgcA) ECB_04170(sgcB)
EBL: ECD_02019(gatB) ECD_02020(gatA) ECD_04167(sgcA) ECD_04170(sgcB)
EBE: B21_01985(gatB) B21_01986(gatA) B21_04129(sgcA) B21_04132(sgcB)
ECC: c2618(gatB) c2619(gatA) c4277 c4278
EKF: KO11_12150(gatA) KO11_12155(gatB)
ELW: ECW_m2294(gatB) ECW_m2295(gatA)
ELL: WFL_11225(gatB) WFL_11230(gatA)
ELP: P12B_c2190(gatB) P12B_c2191(gatA)
ESZ: FEM44_00680(gatB) FEM44_00685(gatA)
STT: t1522 t1525 t3178(gatA) t3179(gatB) t3734 t3735
SPT: SPA1253(sgcA) SPA1256 SPA3127(gatA) SPA3128(gatB) SPA3633 SPA3634
SEC: SCH_1609(sgcB) SCH_1612(sgcA) SCH_3199(ptkA) SCH_3200(ptkB) SCH_3704(ptkB) SCH_3705
SFL: SF2155(gatB) SF2156(gatA)
SFX: S2281(gatB) S2282(gatA)
SFV: SFV_2148(gatB)
SFE: SFxv_2384(gatB) SFxv_2385(gatA)
SFT: NCTC1_02370(gatB) NCTC1_02371(gatA)
SSN: SSON_2140(gatB)
SBO: SBO_0914(gatB) SBO_0915(gatA)
SBC: SbBS512_E1144(gatA) SbBS512_E1145(gatB)
CTU: CTU_04370(gatB) CTU_04380(gatA)
KPN: KPN_03548(gatA) KPN_03549(gatB)
KPU: KP1_4852(gatA) KP1_4853(gatB)
CPOT: FOB25_14250(gatB) FOB25_14255(gatA)
KOR: AWR26_02860(gatB) AWR26_02865(gatA)
PSTS: E05_50930 E05_50940(gatB)
RACE: JHW33_11535(gatA) JHW33_11540(gatB)
MTHI: C7M52_01852(gatB) C7M52_01855(ulaC_2)
HSO: HS_1143(gatB) HS_1144(gatA)
BMQ: BMQ_3202(gatB) BMQ_3203(gatB) BMQ_3204(gatA)
BHA: BH0191(gatB) BH0192(gatA)
VPN: A21D_00396(gatB_1) A21D_00397 A21D_01928(gatB_2) A21D_01930(fruA_7) A21D_02449(gatB_4)
SSH: NCTC13712_00191(fruA_1) NCTC13712_00192(gatB_1)
LMQ: LMM7_0525(gatA-1) LMM7_0529(gatC-1) LMM7_2196(gatB) LMM7_2197(gatA) LMM7_2778(gatB-2) LMM7_2779(gatA-2)
PABS: JIR001_11120(pts35A) JIR001_11130
SGC: A964_0451(gatA) A964_0452(gatB) A964_0455(gatA) A964_0457(gatB)
SDA: GGS_0293
SPSU: NCTC13786_01006(gatB_1) NCTC13786_01008(licR_1)
LAE: LBAT_0301
LCB: LCABL_27620(PTS-EII) LCABL_28420(pts36B) LCABL_28430(pts36A) LCABL_29480(ptkB) LCABL_29490(fruA)
LRH: LGG_00345(gatA) LGG_00346(gatB) LGG_02574(pts) LGG_02666(gatB) LGG_02667(gatA) LGG_02754(gatB) LGG_02755(gatA)
LRL: LC705_00427(pts) LC705_00428(gatA) LC705_02582(pts) LC705_02667(gatA)
LPL: lp_3547(pts35B) lp_3548(pts35A) lp_3599(pts36A) lp_3600(pts36B)
LPJ: JDM1_2833(pts35B) JDM1_2834(pts35A) JDM1_2880(pts36A) JDM1_2881(pts36B)
LPT: zj316_0161(pts35B) zj316_0162(pts35A)
EFN: DENG_00590(gatA) DENG_00591(gatB)
ROB: CK5_19470
PHX: KGNDJEFE_00469(gatA_1) KGNDJEFE_00470(gatB_1) KGNDJEFE_01767(gatB_2) KGNDJEFE_01768(gatA_2)
AWO: Awo_c00070(gatA1) Awo_c00090(gatB1)
TTE: TTE0181(PtsN) TTE0182
TOC: Toce_1446
KME: H0A61_01950(gatA_2) H0A61_01951(gatB_2)
PAUS: NCTC13651_02353(gatB_2) NCTC13651_02355(fryA_1) NCTC13651_02625(gatB_3) NCTC13651_02626(fryA_2)
ACIJ: JS278_00057(gatB_1) JS278_00059(gatA_1) JS278_02510 JS278_02511(gatA_3)
PCAT: Pcatena_01590 Pcatena_03040(pts36B_1) Pcatena_03070(pts35A_1) Pcatena_12360(pts36B_2) Pcatena_12370(pts35A_2)
 » show all
1  [PMID:1100608]
Lengeler J
Nature and properties of hexitol transport systems in Escherichia coli.
J Bacteriol 124:39-47 (1975)
2  [PMID:7772602]
Nobelmann B, Lengeler JW
Sequence of the gat operon for galactitol utilization from a wild-type strain EC3132 of Escherichia coli.
Biochim Biophys Acta 1262:69-72 (1995)
[eco:b2094 b2093]
3  [PMID:8955298]
Nobelmann B, Lengeler JW
Molecular analysis of the gat genes from Escherichia coli and of their roles in galactitol transport and metabolism.
J Bacteriol 178:6790-5 (1996)
[eco:b2094 b2093]
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