KEGG   ENZYME: 2.7.1.210Help
Entry
EC 2.7.1.210                Enzyme                                 

Name
D-erythrulose 4-kinase;
derK (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:D-erythrulose 4-phosphotransferase
Reaction(IUBMB)
ATP + D-erythrulose = ADP + D-erythrulose 4-phosphate [RN:R11461]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
D-erythrulose [CPD:C02022]
Product
ADP [CPD:C00008];
D-erythrulose 4-phosphate [CPD:C03604]
Comment
The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of erythritol and D-threitol.
History
EC 2.7.1.210 created 2016
Orthology
K20902  D-erythrulose 4-kinase
Genes
MMC: Mmcs_2560
MKM: Mkms_2605
MJL: Mjls_2599
MSM: MSMEG_3271
MSG: MSMEI_3187
MSB: LJ00_16260
MSN: LI99_16265
MSH: LI98_16270
MCB: Mycch_3017
MNE: D174_03540
MPHL: MPHLCCUG_02595(dhaK_1)
MVQ: MYVA_3227
GBR: Gbro_4222
AAU: AAur_4135
ACH: Achl_0411
CFL: Cfla_0184
SEN: SACE_5217(dak)
AMQ: AMETH_2242(dak)
PSEA: WY02_18480
PSEE: FRP1_24315
PSEH: XF36_22925
 » show all
Taxonomy
Reference
1  [PMID:26560079]
  Authors
Huang H, Carter MS, Vetting MW, Al-Obaidi N, Patskovsky Y, Almo SC, Gerlt JA
  Title
A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.
  Journal
J Am Chem Soc 137:14570-3 (2015)
DOI:10.1021/jacs.5b08968
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.210
IUBMB Enzyme Nomenclature: 2.7.1.210
ExPASy - ENZYME nomenclature database: 2.7.1.210
BRENDA, the Enzyme Database: 2.7.1.210

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