KEGG   ENZYME: 2.7.1.210
Entry
EC 2.7.1.210                Enzyme                                 

Name
D-erythrulose 4-kinase;
derK (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:D-erythrulose 4-phosphotransferase
Reaction(IUBMB)
ATP + D-erythrulose = ADP + D-erythrulose 4-phosphate [RN:R11461]
Reaction(KEGG)
R11461
Substrate
ATP [CPD:C00002];
D-erythrulose [CPD:C02022]
Product
ADP [CPD:C00008];
D-erythrulose 4-phosphate [CPD:C03604]
Comment
The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of erythritol and D-threitol.
History
EC 2.7.1.210 created 2016
Orthology
K20902  D-erythrulose 4-kinase
Genes
API: 103310956
EFE: EFER_0430
CRO: ROD_03771
RTG: NCTC13098_01632(dhaK_3)
RBAD: H2866_02235
ECA: ECA0866
PATR: EV46_03980
PATO: GZ59_08020
PCC: PCC21_007710
BGJ: AWC36_04290
EBI: EbC_33110
HAM: HALO1390
SALN: SALB1_1908
SME: SM_b20767(dak)
SMX: SM11_pD0159(dak)
SMEL: SM2011_b20767(dak)
SMER: DU99_26245
SFH: SFHH103_05120(dak)
SFD: USDA257_c15770(dhaK1)
SAME: SAMCFNEI73_pC0527(dhaK)
RHL: LPU83_pLPU83c0761(dahK)
OAN: Oant_3102
OAH: DR92_3401
GOX: GOX2222
GOH: B932_2974
GOY: GLS_c23710(dhaK)
MMC: Mmcs_2560
MKM: Mkms_2605
MJL: Mjls_2599
MGRO: FZ046_21415(derK)
MPHL: MPHLCCUG_02595(dhaK_1)
MVQ: MYVA_3227
MAUU: NCTC10437_04726(dhaK_1)
MMAG: MMAD_20660(derK)
GBR: Gbro_4222
SCO: SCO0580(SCF55.04c)
SFA: Sfla_3629
SBH: SBI_04330(dak2)
STRP: F750_3088
SALU: DC74_5668
SALL: SAZ_29940
STRD: NI25_01455
CMI: CMM_0788(dakA)
CMC: CMN_00743(dakA)
MTS: MTES_2016
MLV: CVS47_02771(lerK_1) CVS47_02889(lerK_2)
MOY: CVS54_00536(lerK)
PUE: FV140_05670(dhaL)
ACH: Achl_0411
CFL: Cfla_0184
MPH: MLP_03260
TFU: Tfu_1716
STRR: EKD16_11340(dhaK2)
KRA: Krad_1919
SEN: SACE_4765(dak) SACE_5217(dak)
AOI: AORI_7456
AMQ: AMETH_2242(dak) AMETH_6525(dak)
AMYY: YIM_41195(dhaK2)
PSEE: FRP1_24315
PSEH: XF36_22925
PAUT: Pdca_04900(derK) Pdca_32710
ACTI: UA75_20470
ACAD: UA74_19970
OLS: Olsu_0402
 » show all
Reference
1  [PMID:26560079]
  Authors
Huang H, Carter MS, Vetting MW, Al-Obaidi N, Patskovsky Y, Almo SC, Gerlt JA
  Title
A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.
  Journal
J Am Chem Soc 137:14570-3 (2015)
DOI:10.1021/jacs.5b08968
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.210
IUBMB Enzyme Nomenclature: 2.7.1.210
ExPASy - ENZYME nomenclature database: 2.7.1.210
BRENDA, the Enzyme Database: 2.7.1.210

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