KEGG   ENZYME: 2.7.1.213Help
Entry
EC 2.7.1.213                Enzyme                                 

Name
cytidine kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:cytidine 5'-phosphotransferase
Reaction(IUBMB)
ATP + cytidine = ADP + CMP [RN:R00513]
Reaction(KEGG)
R00513;
(other) R00964 R01666
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Substrate
ATP [CPD:C00002];
cytidine [CPD:C00475]
Product
ADP [CPD:C00008];
CMP [CPD:C00055]
Comment
The enzyme, characterized from the archaeon Thermococcus kodakarensis, participates in a pathway for nucleoside degradation. The enzyme can also act on deoxycytidine and uridine, but unlike EC 2.7.1.48, uridine kinase, it is most active with cytidine.
History
EC 2.7.1.213 created 2016
Pathway
ec00240  Pyrimidine metabolism
Orthology
K21057  cytidine kinase
K22026  nucleoside kinase
Genes
CLB: Clo1100_3013
CCL: Clocl_2480
CCEL: CCDG5_0763
TACI: TDSAC_0711
TAM: Theam_1686
MJA: MJ_0406
MFE: Mefer_1313
MVU: Metvu_0829
MFS: MFS40622_1675
MIF: Metin_0950
MMP: MMP0418
MMD: GYY_02160
MAE: Maeo_1201
MVO: Mvol_1641
MTH: MTH_1544
METC: MTCT_1409
MWO: MWSIV6_0084(rbsK)
METE: tca_01493(adoK)
MST: Msp_0252
MSI: Msm_1389
MRU: mru_0246
MEB: Abm4_0153
MMIL: sm9_2189
MEYE: TL18_00860
MOL: YLM1_0015
METH: MBMB1_0093
MFC: BRM9_0158
MCUB: MCBB_0117
MFV: Mfer_0189
TAC: Ta0880
TVO: TVG1031550(TVG1031550)
PTO: PTO1237
FAI: FAD_0353
CDIV: CPM_1288
MARC: AR505_1785
ABI: Aboo_0480
TKO: TK1843
TON: TON_1686
TGA: TGAM_0187
TSI: TSIB_1949
THE: GQS_06905
THA: TAM4_1366
THM: CL1_1013
TLT: OCC_10494
THS: TES1_1867
TNU: BD01_1774
TEU: TEU_02660
PPAC: PAP_03105
MAC: MA_1373
MBAR: MSBR2_0971
MBAK: MSBR3_0268
MMA: MM_2358
MMAC: MSMAC_2104
METM: MSMTP_2169
MTHE: MSTHC_2425
MTHR: MSTHT_0846
MHOR: MSHOH_2963
MBU: Mbur_0967
MMET: MCMEM_1470
MMH: Mmah_0649
MPY: Mpsy_3162
MHU: Mhun_0077
MLA: Mlab_0932
MBG: BN140_0912(pfkB)
MPI: Mpet_2014
MBN: Mboo_1658
MPL: Mpal_1085
 » show all
Taxonomy
Reference
1  [PMID:25822915]
  Authors
Aono R, Sato T, Imanaka T, Atomi H
  Title
A pentose bisphosphate pathway for nucleoside degradation in Archaea.
  Journal
Nat Chem Biol 11:355-60 (2015)
DOI:10.1038/nchembio.1786
  Sequence
[tko:TK1843]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.213
IUBMB Enzyme Nomenclature: 2.7.1.213
ExPASy - ENZYME nomenclature database: 2.7.1.213
BRENDA, the Enzyme Database: 2.7.1.213

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