KEGG   ENZYME: 2.7.1.215
Entry
EC 2.7.1.215                Enzyme                                 
Name
erythritol kinase (D-erythritol 1-phosphate-forming);
eryA (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:erythritol 1-phosphotransferase
Reaction(IUBMB)
ATP + erythritol = ADP + D-erythritol 1-phosphate [RN:R11536]
Reaction(KEGG)
R11536
Substrate
ATP [CPD:C00002];
erythritol [CPD:C00503]
Product
ADP [CPD:C00008];
D-erythritol 1-phosphate [CPD:C21294]
Comment
The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism. cf. EC 2.7.1.27, erythritol kinase (D-erythritol 4-phosphate-forming).
History
EC 2.7.1.215 created 2016
Orthology
K00862  erythritol kinase (D-erythritol 1-phosphate-forming)
Genes
EFEEFER_0338(eryA)
KOXKOX_14070
KOEA225_1632
KOYJ415_23470
KOMHR38_12805
KOKKONIH1_08010
KOCAB185_28110
KLLBJF97_08390
KLWDA718_20265
KGRJJJ10_20160
RORRORB6_11900
RONTE10_08990
RPLNB1209_19605
RAODSD31_18435
RTGNCTC13098_05403(lyx_2)
IZHFEM41_12540
GQUAWC35_02410
RBADH2866_13060
KLNLH22_12790
PANTPSNIH1_13465
PANSFCN45_09685
PDISD8B20_08520
PERLAC65_07490
SPIUSPICUR_04390
SROSBBH56_05255
HHUAR456_16140
HSVHNO53_17775
MPRIMP3633_1145
MARDIBG28_06475
MFOIJSY38_15310
MPRFJ8N69_12365
ZDFAN401_07995
BHGI6G56_00340
BULBW21_6384
BUDAQ610_18890
VEIVeis_2016
DRGH9K76_09495
MLOmlr7268
MLNA9174_29275
MCIMesci_5322
MOPMesop_5790
MAMMesau_05284
MAMOA6B35_10920
MESWA9K65_029090
MESMEJ066_15400
MHUAMCHK_0787
MJREB229_29855
MERDEB233_25900
MESRFGU64_19800
SMESMc01623(eryA)
SMKSinme_2215
SMQSinmeB_2059
SMXSM11_chr1024(eryA)
SMIBN406_02059(eriA)
SMEGC770_GR4Chr2293
SMELSM2011_c01623(eryA)
SMERDU99_12530
SMDSmed_2159
RHINGR_b17470
SFHSFHH103_05470
SFDUSDA257_c12970(xylB1)
SIXBSY16_3610
SAMESAMCFNEI73_pC1169(eryA)
SINOSS05631_b56380
EADOV14_3647
EAHFA04_11260
ARAArad_7460(lyxX)
ARUIG6M88_17460
RLEpRL120204(eryA)
RLGRleg_5323
RLBRLEG3_09630
RTRRTCIAT899_PC05570
RGARGR602_PC00578
RJGCCGE525_32055
RHRCKA34_19820
RGRFZ934_19120 FZ934_27780
RIIFFM53_025730
RBANJ2J98_21290
RRGJ3P73_24980
RLSHB780_03515
SHZshn_16425
SZOK8M09_21720
SOJK6301_18130 K6301_19070
BMEBMEII0430
BMELDK63_2809
BMIBMEA_B0843
BMZBM28_B0830
BMGBM590_B0827
BMWBMNI_II0804
BMEEDK62_2589
BMFBAB2_0372(eryA)
BMBBruAb2_0368(eryA)
BMCBAbS19_II03490
BAABAA13334_II00824
BABODK55_2362
BABRDO74_2782
BABTDK49_2870
BABBDK48_2329
BABUDK53_2372
BABSDK51_2951
BABCDO78_2688
BMSBRA0864(eryA)
BSIBS1330_II0857(eryA)
BSFBSS2_II0819(eryA)
BSUIBSSP1_II0808
BSUPBSPT1_II0805
BSUVBSPT2_II0806
BSUCBSSP2_II0817
BMTBSUIS_B0857
BSZDK67_2818
BSVBSVBI22_B0856(eryA)
BSWIY71_15315
BSGIY72_15265
BSKBCA52141_II1826
BOLBCOUA_II0864(eryA)
BCARDK60_2555
BCASDA85_14605
BMRBMI_II858(eryA)
BPPBPI_II920(eryA)
BPVDK65_2785
BCETV910_200428(eryA)
BVLBF3285c2_0388
BRUBFS01_12175
BRJBKD03_02250
OINIAR37_20565
BIOBR141012304_20152
OANOant_2911
OAHDR92_3594
OPSA8A54_12275 A8A54_23175
OCHCES85_5819(eryA)
OCRHGK82_17650
OCLGTN27_20210
BRABRADO4795
BBTBBta_3230
AOLS58_28790
BROBRAD285_2448(eryA)
BRKCWS35_34700
BELBE61_33870
BSEPHAP48_0033265
LNEFZC33_03425
BBARRHAL1_00624(eryA)
MEYTM49_19150
MMEDMame_00678(eryA)
AUAM673_13440
AALAIGS74_12595
AALMLUX29_14485
NOHG5V57_07830
LABTFIU93_29490(eryA2)
LAGGB0E33_29565
LIZLGH83_08810 LGH83_10250
RDERD1_3634
RLIRLO149_c008320
OAROA238_c42140
CMARIMCC12053_406
MALGMALG_01287 MALG_04508
TPROGa0080559_TMP2159
SPSESULPSESMR1_04461(eryA)
SAGUCDO87_26095
MALUKU6B_05470
PALXGQA70_00735
RSKRSKD131_4356
PDEPden_4595
PARREOJ32_06595
PAAKFIU66_09035
PLIAE4191_10000
PMAUCP157_02323(eryA)
DONBSK21_15645
THWBMG03_00110
TECAKL02_018065
GFUKM031_18515
PPAFI8N54_11325
RBZB9057_14845
ACRAcry_2571
AMVACMV_28960
KBAA0U89_05180
NCHA0U93_09660
SHUMSTHU_34070(eriA)
SVCSTVA_08840(eriA) STVA_10010
THACCSC3H3_22375
ROBCK5_09680
ELIMB2M23_01245
TEPTepRe1_2212
TAETepiRe1_2380
ASDAS9A_2886
RHBNY08_872
GTABCM27_14835
SGRSGR_224
SGBWQO_33390
SVLStrvi_6131
SRCM271_41670 M271_41825
SMALSMALA_1063 SMALA_1070
SSOII1A49_08810 I1A49_08845
SBHSBI_04000
SDVBN159_5653
SALUDC74_6901
SALLSAZ_35840
STREGZL_01855
SLDT261_1073
SLCSL103_23035
SXISXIM_49270
STRCAA958_27955
SCXAS200_29205
SRWTUE45_01264(lyx) TUE45_03247(eryA_10)
SCLFBB341_19270
SGSAVL59_40705
STSIA4E84_13885
SLSSLINC_3049
SNRSNOUR_08295
SPLULK06_031460
SNWBBN63_23380
SAUOBV401_09110
SVUB1H20_34035
SGVB1H19_34960
SALJSMD11_6891(xylB)
STROSTRMOE7_32490
SFKKY5_0774c
SNZDC008_11515
SGEDWG14_05498(eryA_2)
SGDELQ87_26125
SQZFQU76_32640
SCYAEJ357_15870
SKACP970_39130
SHAWCEB94_14260
SRKFGW37_01400
SFICEIZ62_30525
SPADDVK44_01070
SFYGFH48_26485
SAQUEJC51_17420
SRIMCP984_04760
STSUB7R87_01190
SCHACP983_28305
SCOECP976_15385
SSPBCP982_36500
STUIGCM10017668_23050
SATAC5746_14235
SHARHUT13_24770
SCYGS1361_14500(eryA5)
SFEUIM697_07935
SLIAHA039_07130
SDWK7C20_31755
SCALI6J39_33765
SDDD9753_23455
SINEKI385_37515
SAOVG3H79_02715
MIHBJP65_10715
MCHNHCR76_15420
CPHYB5808_11440
MSPOKXZ72_13065
HUMDVJ78_09530
CACNRN83_00270
PBOPACID_31590
AACIASQ49_06380
ACIJJS278_00483(eryA)
NAQUENKNEFLB_00829(eryA)
MUZH4N58_13395
KFLKfla_6645
KQIF1D05_17945
NGVCDO52_17960 CDO52_20965
STRREKD16_11325(eryA1)
SAIUJ4H86_23820
SROSros_8242
NOABKM31_53990
NOWGBF35_42230
NCXNocox_34710(eryA4)
NGNLCN96_47335
NMLNamu_3325
SENSACE_5218(eryA) SACE_6531(eryA)
SACGFDZ84_01160
SVISvir_13300 Svir_32110
AOIAORI_7453
AJAAJAP_38980
AMQAMETH_6522(eryA)
AMYCCU254_36075
AABA4R43_36905
AMYYYIM_41180(eryA12)
PMADBAY61_28755
ATLAthai_12420(eriA) Athai_29770
ASERAsera_44790
SNASnas_4068
ACTTDDD63_02460
FSLEJO69_06515 EJO69_06570
FLHEJ997_07495
AEYCDG81_00555
RUBGBA63_01835
CAPCLDAP_16690(xylB) CLDAP_24770(xylB)
TTRTter_2480
HJEHacjB3_16706
SRUBC2R22_03450
HAEhalTADL_2660
HSALJMJ58_01975
NOUNatoc_1232 Natoc_1262 Natoc_1269
 » show all
Reference
1  [PMID:163226]
  Authors
Sperry JF, Robertson DC
  Title
Erythritol catabolism by Brucella abortus.
  Journal
J Bacteriol 121:619-30 (1975)
DOI:10.1128/JB.121.2.619-630.1975
Reference
2  [PMID:12639570]
  Authors
Lillo AM, Tetzlaff CN, Sangari FJ, Cane DE
  Title
Functional expression and characterization of EryA, the erythritol kinase of Brucella abortus, and enzymatic synthesis of L-erythritol-4-phosphate.
  Journal
Bioorg Med Chem Lett 13:737-9 (2003)
DOI:10.1016/S0960-894X(02)01032-6
  Sequence
[bmf:BAB2_0372]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.215
IUBMB Enzyme Nomenclature: 2.7.1.215
ExPASy - ENZYME nomenclature database: 2.7.1.215
BRENDA, the Enzyme Database: 2.7.1.215

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