| Entry |
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| Name |
3-dehydrotetronate 4-kinase;
otnK (gene name)
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
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| Sysname |
ATP:3-dehydrotetronate 4-phosphotransferase
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| Reaction(IUBMB) |
(1) ATP + 3-dehydro-L-erythronate = ADP + 3-dehydro-4-phospho-L-erythronate [RN: R11706];
(2) ATP + 3-dehydro-D-erythronate = ADP + 3-dehydro-4-phospho-D-erythronate [RN: R11707]
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| Reaction(KEGG) |
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| Substrate |
ATP [CPD: C00002];
3-dehydro-L-erythronate [CPD: C21612];
3-dehydro-D-erythronate [CPD: C03064]
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| Product |
ADP [CPD: C00008];
3-dehydro-4-phospho-L-erythronate [CPD: C21611];
3-dehydro-4-phospho-D-erythronate [CPD: C21610]
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| Comment |
The enzyme, characterized from bacteria, is involved in D-erythronate and L-threonate catabolism.
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| History |
EC 2.7.1.217 created 2017
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| Orthology |
| K21948 | 3-dehydrotetronate 4-kinase |
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| Genes |
| EDJ: | ECDH1ME8569_2647(ygbK) |
| KPZ: | KPNIH27_12265 KPNIH27_26665 |
| KPS: | KPNJ2_02874 KPNJ2_05578 |
| LEH: | C3F35_03350 C3F35_26230 |
| SOF: | NCTC11214_05426 NCTC11214_05427 |
| PLF: | PANA5342_1628(ygbK1) |
| PAO: | Pat9b_4212 Pat9b_4405 |
| TCI: | A7K98_03145 A7K98_20755 |
| POR: | APT59_09425 APT59_16245 |
| PVD: | CFBP1590_0485 CFBP1590_0485A(hopAN1) |
| PTN: | PTRA_a2902 PTRA_a2906 |
| AGQ: | LQZ07_05795 LQZ07_24010 |
| GAI: | IMCC3135_12980 IMCC3135_20435 |
| HHU: | AR456_06570 AR456_16080 |
| HHH: | CLM76_07425 CLM76_07555 |
| HOL: | HORIV_63850 HORIV_63860 HORIV_64540 |
| HPRO: | LMS44_20310 LMS44_20450 |
| ZDF: | AN401_07785 AN401_17910 |
| REH: | H16_A1561(h16_A1561) |
| CNC: | CNE_1c15820 CNE_BB1p10110 |
| BCAI: | K788_0001843 K788_0007623 |
| PDIO: | PDMSB3_0938.1(otnK) |
| XYK: | GT347_00455 GT347_12065 |
| MESW: | A9K65_001305 A9K65_021630 |
| NKI: | KW403_07335 KW403_07580 KW403_09395 |
| ORM: | HTY61_11185 HTY61_11870 |
| RHI: | NGR_b20350 NGR_c06120 |
| SIX: | BSY16_5001 BSY16_5701 |
| SAME: | SAMCFNEI73_pC0329 SAMCFNEI73_pC0606 |
| REI: | IE4771_PA00075 IE4771_PD00359 |
| RHL: | LPU83_pLPU83c0746 LPU83_pLPU83d1676 |
| RGA: | RGR602_CH03643 RGR602_PA00058 RGR602_PC01501 |
| RAD: | CO657_03035 CO657_27130 |
| RLW: | RlegWSM1455_05240 RlegWSM1455_28350 |
| BSW: | IY71_09840 IY71_11820 |
| BSG: | IY72_09580 IY72_11360 |
| BJA: | blr2930(blr2930) blr3541(blr3541) |
| BOP: | AXW83_01585 AXW83_15495 |
| BVV: | BHK69_01925 BHK69_12280 |
| APOL: | K9D25_04030 K9D25_23065 |
| MEE: | DA075_13525 DA075_18795 |
| MTEA: | DK419_06720 DK419_10220 |
| LABR: | CHH27_00075 CHH27_27470 |
| OAT: | OAN307_c00550 OAN307_c20300 |
| YAN: | AYJ57_10775 AYJ57_17390 |
| THAA: | CFI11_02885 CFI11_24210 |
| PMAU: | CP157_00438(otnK_1) |
| TEC: | AKL02_004305 AKL02_020890 |
| RGI: | RGI145_01225 RGI145_06195 |
| ROS: | CTJ15_11205 CTJ15_17375 |
| RMUC: | FOB66_08010 FOB66_21155 |
| RMT: | IAI58_08315 IAI58_13540 |
| RCV: | PFY06_13005 PFY06_18860 PFY06_19300 |
| LCK: | HN018_02205 HN018_23185 |
| CBOL: | CGC65_23035 CGC65_25215 CGC65_30405 |
| MMAT: | MMAGJ_15250 MMAGJ_35960 |
| MGO: | AFA91_03825 AFA91_08280 AFA91_23270 |
| RKO: | JWS14_40840 JWS14_42345 |
| SRC: | M271_39945 M271_48030 |
| AHEL: | Q31a_35830 Q31a_38400 |
| PND: | Pla175_19320 Pla175_51090 |
| SSM: | Spirs_1255 Spirs_1661 Spirs_3278 |
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| Reference |
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| Authors |
Zhang X, Carter MS, Vetting MW, San Francisco B, Zhao S, Al-Obaidi NF, Solbiati JO, Thiaville JJ, de Crecy-Lagard V, Jacobson MP, Almo SC, Gerlt JA |
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| Title |
Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.7.1.217 |
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