KEGG   ENZYME: 2.7.1.224Help
Entry
EC 2.7.1.224                Enzyme                                 

Name
cytidine diphosphoramidate kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:cytidine 5'-diphosphoramidate 3'-phosphotransferase
Reaction(IUBMB)
ATP + cytidine 5'-diphosphoramidate = ADP + cytidine 3'-phospho-5'-diphosphoramidate [RN:R12246]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
cytidine 5'-diphosphoramidate [CPD:C22031]
Product
ADP [CPD:C00008];
cytidine 3'-phospho-5'-diphosphoramidate [CPD:C22032]
Comment
The enzyme, characterized from the bacterium Campylobacter jejuni, is involved in formation of a unique O-methyl phosphoramidate modification on specific sugar residues within the bacterium's capsular polysaccharides.
History
EC 2.7.1.224 created 2018
Orthology
K23148  cytidine diphosphoramidate kinase
Genes
PMK: MDS_1833
PCH: EY04_30545
PCZ: PCL1606_01930
PCP: JM49_01225
PSEM: TO66_30400
OME: OLMES_3121
AEO: O23A_p3858
ADH: CK627_03040
THO: SP60_02255
BBRO: BAU06_24715
HHE: HH_1438(cysC)
WSU: WS2182(CYSC)
CJE: Cj1415c(cysC)
CJB: BN148_1415c(cysC)
CJU: C8J_0653
CJI: CJSA_1346(cysC)
CJM: CJM1_0668(cysC)
CJEJ: N564_01412
CJEU: N565_01452
CJEN: N755_01449
CJEI: N135_01504
CJER: H730_08030
CJY: QZ67_01550(cysC)
CJQ: UC78_1357(cysC)
CFZ: CSG_17610
CLA: CLA_0317
CCF: YSQ_05920
CCY: YSS_03170
CCOI: YSU_05570
CIS: CINS_0308
CVO: CVOL_1296
CHYO: CHH_1591
CHV: CHELV3228_0537(cysC)
CCUN: CCUN_0686(cysC)
RBM: TEF_17265
MGY: MGMSRv2__3431(cysC)
MAGX: XM1_2457
MAI: MICA_1010
 » show all
Taxonomy
Reference
1  [PMID:29578334]
  Authors
Taylor ZW, Raushel FM
  Title
Cytidine Diphosphoramidate Kinase: An Enzyme Required for the Biosynthesis of the O-Methyl Phosphoramidate Modification in the Capsular Polysaccharides of Campylobacter jejuni.
  Journal
Biochemistry 57:2238-2244 (2018)
DOI:10.1021/acs.biochem.8b00279
  Sequence
[cje:Cj1415c]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.224
IUBMB Enzyme Nomenclature: 2.7.1.224
ExPASy - ENZYME nomenclature database: 2.7.1.224
BRENDA, the Enzyme Database: 2.7.1.224

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