KEGG   ENZYME: 2.7.1.225Help
Entry
EC 2.7.1.225                Enzyme                                 

Name
L-serine kinase (ATP);
sbnI (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:L-serine 3-phosphotransferase
Reaction(IUBMB)
ATP + L-serine = ADP + O-phospho-L-serine [RN:R12344]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
L-serine [CPD:C00065]
Product
ADP [CPD:C00008];
O-phospho-L-serine [CPD:C01005]
Comment
The enzyme, characterized from the bacterium Staphylococcus aureus, is involved in the biosynthesis of L-2,3-diaminopropanoate, which is used by that organism as a precursor for the biosynthesis of the siderophore staphyloferrin B.
History
EC 2.7.1.225 created 2019
Pathway
ec00997  Biosynthesis of various secondary metabolites - part 3
ec01100  Metabolic pathways
Orthology
K23371  L-serine kinase (ATP) / ParB family transcriptional regulator, heme-responsive regulator
Genes
BTHR: YBT1520_29789
BTHI: BTK_29574
BTHT: H175_233p021 H175_328p222 H175_328p225
BBY: CY96_29570
SAU: SA0120(sbnI)
SAV: SAV0124
SAW: SAHV_0123
SAH: SaurJH1_0115
SAJ: SaurJH9_0111
SAM: MW0097(sbnI)
SAS: SAS0098
SAR: SAR0127
SAC: SACOL0108
SAE: NWMN_0068(sbnI)
SAD: SAAV_0092
SUU: M013TW_0114(sbnI)
SUE: SAOV_0071
SUJ: SAA6159_00107(sbnl)
SUK: SAA6008_00102(sbnl)
SUC: ECTR2_80
SUZ: MS7_0116
SUW: SATW20_01360(sbnI)
SUG: SAPIG0136
SUF: SARLGA251_00990(sbnI)
SAUA: SAAG_00608
SAUS: SA40_0091
SAUU: SA957_0106
SAUG: SA268_0103(sbnI)
SAUZ: SAZ172_0135(sbnI)
SAUT: SAI1T1_2000800(sbnl)
SAUJ: SAI2T2_1000800(sbnl)
SAUK: SAI3T3_1000800(sbnl)
SAUQ: SAI4T8_1000800(sbnl)
SAUF: X998_0103
SAB: SAB0063
SUY: SA2981_0125(sbnI)
SAUB: C248_0112
SAUM: BN843_1260
SAUC: CA347_135
SAUR: SABB_01716(sbnI)
SAUI: AZ30_00645
SAUD: CH52_05100
SAMS: NI36_00540
SDT: SPSE_2116
SHU: SHYC_00395(sbnI)
SSCH: LH95_00395
SSCZ: RN70_00615
SAGQ: EP23_09730
 » show all
Taxonomy
Reference
1  [PMID:29483190]
  Authors
Verstraete MM, Perez-Borrajero C, Brown KL, Heinrichs DE, Murphy MEP
  Title
SbnI is a free serine kinase that generates O -phospho-l-serine for staphyloferrin B biosynthesis in Staphylococcus aureus.
  Journal
J Biol Chem 293:6147-6160 (2018)
DOI:10.1074/jbc.RA118.001875
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.225
IUBMB Enzyme Nomenclature: 2.7.1.225
ExPASy - ENZYME nomenclature database: 2.7.1.225
BRENDA, the Enzyme Database: 2.7.1.225

DBGET integrated database retrieval system