KEGG   ENZYME: 2.7.1.230Help
Entry
EC 2.7.1.230                Enzyme                                 

Name
amicoumacin kinase;
amiN (gene name);
yerI (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:amicoumacin A 2-phosphotransferase
Reaction(IUBMB)
ATP + amicoumacin A = ADP + amicoumacin A 2-phosphate [RN:R12530]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
amicoumacin A [CPD:C22231]
Product
ADP [CPD:C00008];
amicoumacin A 2-phosphate [CPD:C22232]
Comment
The enzyme, found in some bacterial species, inactivates the antibiotic amicoumacin A by phosphorylating it, conferring resistance on the bacteria.
History
EC 2.7.1.230 created 2019
Orthology
K23983  amicoumacin kinase
Genes
ALG: AQULUS_20860(thrB)
LPO: LPO_p0012
LPP: plpp0135
LHA: LHA_pA0092
LSH: CAB17_19725
GAI: IMCC3135_30660(srkA_4)
BGD: bgla_2g27100
BGO: BM43_6442
BGP: BGL_2c03950
BPLA: bpln_2g04410
CCX: COCOR_03490(yerI)
SCL: sce4853
BSU: BSU06640(yerI)
BSR: I33_0753
BSL: A7A1_3129
BSH: BSU6051_06640(yerI)
BSUT: BSUB_00735(yerI)
BSUL: BSUA_00735(yerI)
BSUS: Q433_03765
BSS: BSUW23_03370(yerI)
BST: GYO_0926
BSO: BSNT_07043(yerI)
BSQ: B657_06640(yerI)
BSX: C663_0688(yerI)
BAQ: BACAU_0675(yerI)
BYA: BANAU_0620(yerI)
BAMP: B938_03270
BAML: BAM5036_0625(yerI)
BAMA: RBAU_0683(yerI)
BAMN: BASU_0655(yerI)
BAMB: BAPNAU_0631(yerI)
BAMT: AJ82_03930
BAMY: V529_06300(yerI)
BMP: NG74_00692(thrB_1)
BAO: BAMF_0659(yerI)
BAZ: BAMTA208_03100(yerI)
BQL: LL3_00708(yerI)
BXH: BAXH7_00652(yerI)
BQY: MUS_0681(yerI)
BAMI: KSO_016250
BAMC: U471_06780
BAMF: U722_03500
BHA: BH3399
BAR: GBAA_0637
BAT: BAS0604
BAI: BAA_0719
BANT: A16_06980
BANR: A16R_07040
BANS: BAPAT_0614
BANV: DJ46_5095
BCA: BCE_0705
BCQ: BCQ_0705
BCX: BCA_0675
BNC: BCN_0614
BCF: bcf_03275
BCER: BCK_04970
BTL: BALH_0578
BTT: HD73_0712
BTHI: BTK_03640
BTM: MC28_5365
BTG: BTB_c06510(yerI1)
BTI: BTG_17970
BTW: BF38_1884
BWW: bwei_4961(yerI)
BMYO: BG05_5284
BMYC: DJ92_3239
BCL: ABC1398
BPU: BPUM_0640
BPUM: BW16_03450
BPUS: UP12_03555
BJS: MY9_0754
BACW: QR42_03365
BACP: SB24_06340
BACB: OY17_06160
BACY: QF06_02245
BACL: BS34A_07610(thrB_1)
BALM: BsLM_0696
LSP: Bsph_2648
PSYO: PB01_02185
PPM: PPSC2_17495(hsK1)
PPO: PPM_3529(hsK1)
PMW: B2K_06445
PSAB: PSAB_11735
JEO: JMA_05920
CBB: CLD_3202
AOE: Clos_0340
BPB: bpr_I2773
AMR: AM1_0146
MAR: MAE_18490
MPK: VL20_4724
CPI: Cpin_3723
FLN: FLA_2492
MUC: MuYL_3025
SLI: Slin_2085
EAO: BD94_0543
ELB: VO54_02070(thrB_2)
CHZ: CHSO_4345
MARF: CJ739_2776
MBAK: MSBR3_0822
 » show all
Taxonomy
Reference
1  [PMID:30181282]
  Authors
Terekhov SS, Smirnov IV, Malakhova MV, Samoilov AE, Manolov AI, Nazarov AS, Danilov DV, Dubiley SA, Osterman IA, Rubtsova MP, Kostryukova ES, Ziganshin RH, Kornienko MA, Vanyushkina AA, Bukato ON, Ilina EN, Vlasov VV, Severinov KV, Gabibov AG, Altman S
  Title
Ultrahigh-throughput functional profiling of microbiota communities.
  Journal
Proc Natl Acad Sci U S A 115:9551-9556 (2018)
DOI:10.1073/pnas.1811250115
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.230
IUBMB Enzyme Nomenclature: 2.7.1.230
ExPASy - ENZYME nomenclature database: 2.7.1.230
BRENDA, the Enzyme Database: 2.7.1.230

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