KEGG   ENZYME: 2.7.1.232
Entry
EC 2.7.1.232                Enzyme                                 
Name
levoglucosan kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:1,6-anhydro-beta-D-glucopyranose 6-phosphotransferase (hydrolyzing)
Reaction(IUBMB)
ATP + levoglucosan + H2O = ADP + D-glucose 6-phosphate [RN:R12746]
Reaction(KEGG)
R12746
Substrate
ATP [CPD:C00002];
levoglucosan [CPD:C22350];
H2O [CPD:C00001]
Product
ADP [CPD:C00008];
D-glucose 6-phosphate [CPD:C00092]
Comment
Levoglucosan is formed from the pyrolysis of carbohydrates such as starch and cellulose and is an important molecular marker for pollution from biomass burning. The enzyme, found in yeast and fungi, requires a magnesium ion. cf. EC 1.1.1.425, levoglucosan dehydrogenase.
History
EC 2.7.1.232 created 2021
Orthology
K25043  levoglucosan kinase
Genes
PICPICST_36132
PGUPGUG_04600
SLBAWJ20_2341
NCRNCU06383
NTENEUTE1DRAFT108710(NEUTE1DRAFT_108710)
TMNUCRPA7_1136
SSCKSPSK_09294
FOXFOXG_14970
TRETRIREDRAFT_5614 TRIREDRAFT_67642
TRRM419DRAFT_11892 M419DRAFT_80113
MAJMAA_07772
PLJVFPFJ_02025
VALVDBG_09018
VDAVDAG_10459
SAPOSAPIO_CDS8834
ELAUCREL1_4330
PSCOLY89DRAFT_609597
ANIAN3499.2
AFMAFUA_4G14600
NFINFIA_014600 NFIA_101770
AORAO090103000264
ANGANI_1_320044(An05g02500)
AFVAFLA_013261
ALUCAKAW2_81384A
ACHEACHE_10215A ACHE_30518A
APUUAPUU_10004A APUU_40148S APUU_40640S
PCSPc12g08720
PDPPDIP_36080
TRGTRUGW13939_08486
AALTCC77DRAFT_1019273
ZTRMYCGRDRAFT_84209
NPAUCRNP2_1025
 » show all
Reference
1  [PMID:12356473]
  Authors
Zhuang X, Zhang H.
  Title
Identification, characterization of levoglucosan kinase, and cloning and expression of levoglucosan kinase cDNA from Aspergillus niger CBX-209 in Escherichia coli.
  Journal
Protein Expr Purif 26:71-81 (2002)
DOI:10.1016/s1046-5928(02)00501-6
Reference
2
  Authors
Dai, J., Yu, Z., He, Y., Zhang, L., Bai, Z., Dong, Z., Du, Y. and Zhang, H.
  Title
Cloning of a novel levoglucosan kinase gene from Lipomyces starkeyi and its expression in Escherichia coli.
  Journal
World J Microbiol Biotechnol 25:1589-1595 (2009)
Reference
3  [PMID:21719279]
  Authors
Layton DS, Ajjarapu A, Choi DW, Jarboe LR.
  Title
Engineering ethanologenic Escherichia coli for levoglucosan utilization.
  Journal
Bioresour Technol 102:8318-22 (2011)
DOI:10.1016/j.biortech.2011.06.011
  Sequence
Reference
4  [PMID:26433384]
  Authors
Islam ZU, Zhisheng Y, Hassan el B, Dongdong C, Hongxun Z.
  Title
Microbial conversion of pyrolytic products to biofuels: a novel and sustainable approach toward second-generation biofuels.
  Journal
J Ind Microbiol Biotechnol 42:1557-79 (2015)
DOI:10.1007/s10295-015-1687-5
Reference
5  [PMID:26354439]
  Authors
Bacik JP, Klesmith JR, Whitehead TA, Jarboe LR, Unkefer CJ, Mark BL, Michalczyk R.
  Title
Producing glucose 6-phosphate from cellulosic biomass: structural insights into levoglucosan bioconversion.
  Journal
J Biol Chem 290:26638-48 (2015)
DOI:10.1074/jbc.M115.674614
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.232
IUBMB Enzyme Nomenclature: 2.7.1.232
ExPASy - ENZYME nomenclature database: 2.7.1.232
BRENDA, the Enzyme Database: 2.7.1.232

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