KEGG   ENZYME: 2.7.1.237
Entry
EC 2.7.1.237                Enzyme                                 
Name
GTP-dependent dephospho-CoA kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
GTP:3'-dephospho-CoA 3'-phosphotransferase
Reaction(IUBMB)
GTP + 3'-dephospho-CoA = GDP + CoA [RN:R12608]
Reaction(KEGG)
R12608
Substrate
GTP [CPD:C00044];
3'-dephospho-CoA [CPD:C00882]
Product
GDP [CPD:C00035];
CoA [CPD:C00010]
Comment
The enzyme, characterized from the archaeon Thermococcus kodakarensis, participates in a coenzyme A biosynthesis pathway. cf. EC 2.7.1.24, dephospho-CoA kinase.
History
EC 2.7.1.237 created 2022
Pathway
ec00770  Pantothenate and CoA biosynthesis
ec01100  Metabolic pathways
Orthology
K09735  GTP-dependent dephospho-CoA kinase
Genes
BROCIPI25_09700
MJAMJ_0395
MFEMefer_0874
MVUMetvu_1473
MFSMFS40622_0924
MIFMetin_1063
MJHJH146_1441
MESGMLAUSG7_0125
MESAMLASG1_1308
MIGMetig_1028
MMPMMP0442
MMQMmarC5_1195
MMXMmarC6_0469
MMZMmarC7_1439
MMDGYY_02285
MMAKMMKA1_04630
MMAOMMOS7_04580
MMADMMJJ_05890
MAEMaeo_0282
MVNMevan_1427
MVOMvol_0003
MOKMetok_0224
METFCFE53_03730
MTHMTH_266
MMGMTBMA_c07160
MWOMWSIV6_0682
MTEEMTTB_09090
METCMTCT_0229
METEtca_00246
METZMETMT2_0712
METKFVF72_00970
MTHMFZP57_03270
METJFZP68_08275
MSTMsp_0622
METBAW729_04485
MRUmru_1479
MSIMsm_0195
MEBAbm4_0719
MMILsm9_0851
MEYETL18_06060
MOLYLM1_0979
MAROMarbSA_20540
METVK4897_01435
MELMetbo_0600
MEWMSWAN_1762
METHMBMB1_1384
MFCBRM9_0610
MFIDSM1535_0592
MCUBMCBB_1627
MSUBBK009_05930
METNBK008_01475
METTCIT01_10250
METOCIT02_11055
MEMEHYG87_00025
MFVMfer_0440
MKAMK1453
AFUAF_1115
AFGAFULGI_00012120
APOArcpr_0603
AVEArcve_0850
ASTAsulf_00085
FPLFerp_2227
GACGACE_0913
GAHGAH_01873
PFUPF0254
PFIPFC_00325
PHOPH1909(PH1909)
PABPAB1106
PYNPNA2_0897
PYAPYCH_13340
PYSPy04_0405
PYCTQ32_01095
TKOTK1697
TONTON_1911
TGATGAM_0501
TSITSIB_0028
TBATERMP_02014
THEGQS_05635
THATAM4_775
THMCL1_0760
TLTOCC_01504
THSTES1_1964
TNUBD01_1507
TEUTEU_03975
TGYX802_06475
THVADU37_CDS22000
TCHCHITON_0468
TPEPA0127_06760
TPIEA7C91_05570
TGGA3K92_06810
TCEA3L02_01610
TBSA3L01_00235
THHCDI07_00265
TSLA3L11_03960
TTDA3L14_01535
TPRFA3L09_09680
TRLA3L10_09930
TPAFA3L08_03370
THYA3L12_03260
TICFH039_02330
TCQTIRI35C_0264
THEMFPV09_07020
THEIK1720_03200
PPACPAP_00780
MBAMbar_A0283
MBYMSBRM_2670
MBWMSBRW_0713
MBARMSBR2_2628
MBAKMSBR3_2797
MACMA_3694
MMAMM_0598
MMAZMmTuc01_0605
MMJMSMAS_0711
MMACMSMAC_0712
MVCMSVAZ_0652
MEKMSKOL_0630
MLSMSLAZ_2263
METMMSMTP_0914
MEFMSWH1_2401
MEQMSWHS_2646
MSJMSSAC_3524
MSZMSSIH_3043
MSWMSSIT_3101
MTHRMSTHT_2418
MTHEMSTHC_0864
MHORMSHOH_0826
MFZAOB57_003335
MBUMbur_2282
MMETMCMEM_0431
MELOJ7W08_00185
MMHMmah_0492
MHAZBHR79_00965
MEVMetev_0570
MZHMzhil_0482
MPYMpsy_0973
MZIHWN40_03670
MHZMetho_0556
MTPMthe_1323
MCJMCON_3184
MHIMhar_1913
MHUMhun_2865
MRTJKHC33_02625
MLAMlab_0656
MEMMemar_2244
MBGBN140_1416
MEMAMMAB1_1818
MCHKMchiMG62_25630
MPIMpet_0093
MENDL6E24_07595
MBNMboo_0243
MFOMetfor_2870
MPLMpal_0601
MPDMCP_2673
MEZMtc_0179
RCIRCIX625
HSLOE_3871R
HDLHALDL1_15130
HHBHhub_3346
HAGSJT689_09590
HABOJRZ79_07970
HNOLT974_13540
HLULT972_01210
HANRLJ422_08240
HJEHacjB3_03895
HALHHTSR_1917
HHSRHSR6_1986
HSUHLASF_1983
HSFHLASA_1969
SALRFQU85_05895
HALREFA46_002695
HAADMW046_09420
HALXM0R89_04295
HAXZM0R88_04355
SALIL593_13905
SAIMK0C01_04525
HARAAArcS_2496
HMArrnAC2831
HHIHAH_0110
HHNHISP_00625
HABSG26_08490
HTABVU17_00520
HALJG9465_02065
HSINKDQ40_12850
NPHNP_5076A
NMONmlp_1554
NHOHWV23_05775
NSALHWV07_16765
HUTHuta_2205
HTIHTIA_2044
HALAHrd1104_02720
HMUHmuk_0726
HALZE5139_06810
HALLLC1Hm_3238
HAZPGBQ70_06805
HALIBV210_07700
HSNDV733_00525
HDSHSR122_2313
HRRHZS55_03015
HPELHZS54_02690
HLTI7X12_09085
HARCHARCEL1_10780
HDOMUK72_04610
HWAHQ_1339A
HWCHqrw_1400
HVOHVO_1897
HMEHFX_1988
HGIABY42_09205
HALEG3A49_12490
HLSKU306_03040
HBOHbor_05020
HAQDU484_03485
HAJDU500_03940
HAERDU502_01850
HRAEI982_11560
HLMDV707_13770
HALMFCF25_00870
HLAHlac_2394
HALPDOS48_12120
HALBEKH57_13270
HEZZEO776_13045
HALQHrr1229_008985
HSSJ7656_03245
HSAIHPS36_08590
HAZZKI388_11615
SRUBC2R22_17475
HAEhalTADL_3267
HALNB4589_011490
HALGHUG10_10895
HALUHUG12_05260
HMPK6T50_09310
HREK6T36_09085
HRMK6T25_06805
HACBHbl1158_01230
HDFAArcSl_0228
HAHHalar_2725
HTUHtur_3456
HDABB347_15935
HSALJMJ58_11080
HLOJ0X27_07220
HAKZJ0X25_04995
NMGNmag_1490
HXAHalxa_3489
NATNJ7G_2519
NPENatpe_0550
NVRFEJ81_03105
NPLFGF80_07815
NAYHYG81_07500
HALYHYG82_10240
HJTDVR14_11980
NGENatgr_2317
HRUHalru_2544
NOUNatoc_2359
HLRHALLA_17910
HLCCHINAEXTREME07090
NAJB1756_04160
NAGAArcMg_0257
NANAArc1_0258
NBGDV706_05115
NASGCU68_08180
SAWLNGM29_00215
MELUMTLP_02990
MEAMMU439_04510
TACTa1091
TVOTVG0468984(TVG0468984)
PTOPTO0868
FACFACI_IFERC01G1477
FAIFAD_0459
CDIVCPM_1268
TARTALC_00505
MAXMMALV_04390
MERMMINT_07120
MEARMpt1_c03740
MEUZKRP56_05870
MARCAR505_1372
ABIAboo_0566
ACFAciM339_0483
APEAPE_0256
ACJACAM_0194
SMRSmar_0835
SHCShell_1632
IHOIgni_0082
IISEYM_05595
DKADKAM_1343
DFDDesfe_1439
DMUDesmu_1335
TAGTagg_1373
IAGIgag_1897
THGTCELL_0550
HBUHbut_0437
PFMPyrfu_0254
PDLPyrde_0121
STOSTK_03780
SOHD1869_01615
SSOSSO0416
SOLSsol_1393
SSOASULA_1439
SSOLSULB_1440
SSOFSULC_1438
SSHIJ5U23_03020
SCASSACC_06120
SAISaci_0836
SACNSacN8_04055
SACRSacRon12I_04045
SACSSUSAZ_03790
SISLS215_1816
SIAM1425_1688
SIMM1627_1804
SIDM164_1735
SIYYG5714_1804
SINYN1551_1122
SIILD85_1945
SIHSiH_1663
SIRSiRe_1584
SICSiL_1576
SULABFU36_03730
SULEGFS03_09485
SULOGFS33_01300
SULLEWF20_03085
MSEMsed_2239
MEMJMJ1HA_2559
MCNMcup_0069
MHKDFR87_07340
MPRUDFR88_07025
MTENGWK48_04825
MJNMjAS7_0531
AHOAhos_0710
AMANB6F84_06985
ASULDFR86_06045
AAMBD1866_11335
ACIHHS5_20840
SACDHS1genome_0341
SAZOD1868_02535
CSTYKN1_19950
STEPIC006_1511
SAHSHS7_06830
PAIPAE3284
PISPisl_0494
PCLPcal_1764
PASPars_1711
PYRP186_1323
POGPogu_0423
TNETneu_1532
PYWPYWP30_01679
CMACmaq_1963
TTNTTX_0546
TUZTUZN_0189
VDIVdis_2228
VMOVMUT_0665
TPETpen_0578
THELIG193_04965
ASCASAC_1120
ACIASE86_06740
CLGCalag_0421
FFOFFONT_0441
NMRNmar_1233
NIRNSED_06915
NKRNKOR_06995
NIDNPIRD3C_0878
NINNADRNF5_0710
NIWNisw_07555
NCLC5F47_06740
NOXC5F49_06715
NUEC5F50_09325
NIPNsoK4_01840
NCTNMSP_0442
NICDSQ20_07700
CSYCENSYa_0966
NGANgar_c18380
NVNNVIE_003780
NEVNTE_01707
TAANMY3_01470
NFNNFRAN_2364
NCVNCAV_0850
CSUCSUB_C0436
NBVT478_0497
TAHSU86_000050
NIUDSQ19_06935
NDVNDEV_1216
CCAINAS2_0370
KCRKcr_1362
BARCAOA65_1090
BARBAOA66_1285
FLTSv326_1062
LOKILokiarch_06350 Lokiarch_42000
PSYTDSAG12_03403
 » show all
Reference
1  [PMID:31337720]
  Authors
Shimosaka T, Makarova KS, Koonin EV, Atomi H
  Title
Identification of Dephospho-Coenzyme A (Dephospho-CoA) Kinase in Thermococcus kodakarensis and Elucidation of the Entire CoA Biosynthesis Pathway in Archaea.
  Journal
mBio 10:e01146-19 (2019)
DOI:10.1128/mBio.01146-19
  Sequence
[tko:TK1697]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.237
IUBMB Enzyme Nomenclature: 2.7.1.237
ExPASy - ENZYME nomenclature database: 2.7.1.237
BRENDA, the Enzyme Database: 2.7.1.237

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