Entry |
|
Name |
mevalonate kinase;
mevalonate kinase (phosphorylating);
mevalonate phosphokinase;
mevalonic acid kinase;
mevalonic kinase;
mevalonate 5-phosphotransferase ;
MVA kinase;
ATP:mevalonate 5-phosphotransferase
|
Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
|
Sysname |
ATP:(R)-mevalonate 5-phosphotransferase
|
Reaction(IUBMB) |
ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate [RN: R02245]
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Reaction(KEGG) |
|
Substrate |
|
Product |
|
Comment |
CTP, GTP and UTP can also act as donors.
|
History |
EC 2.7.1.36 created 1961
|
Pathway |
ec00900 | Terpenoid backbone biosynthesis |
ec01110 | Biosynthesis of secondary metabolites |
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Orthology |
|
Genes |
PCAD: | 102975327 102997048(MVK) |
PGUT: | 117672291(MVK) 132708919 |
SANH: | 107654617 107672634 |
SASA: | 106580105(mvk) 106585666 |
STRU: | 115164855 115199805(mvk) |
OMY: | 110525361 110535761(mvk) |
OGO: | 124034560 124036044(mvk) |
ONE: | 115110986(mvk) 115139767 |
OKI: | 109871508 109895662(mvk) |
OKE: | 118358062(mvk) 118394029 |
SALP: | 111957628 111974242 |
SNH: | 120049778(mvk) 120063075 |
CCLU: | 121550746 121584528(mvk) |
PSPA: | 121296782 121299935 |
ARUT: | 117426554 117427823 |
DSI: | Dsimw501_GD25827(Dsim_GD25827) |
ASTE: | 118509278 118515243 |
MPHA: | 105828662 105836044 |
AEC: | 105145884 105150268 105150269 105150273 105150274 105150815 |
ACEP: | 105619134 105624314 |
PBAR: | 105423753 105423755 105428850 105428852 105428853 105428977 105430624 105430625 105430630 105430631 105430684 105430685 105430686 105430688 105430689 105430692 105431894 105432258 105432724 105433100 |
VEM: | 105562799 105569633 105570092 |
CFO: | 105250768 105252027 105252566 105254848 105256679 105256680 105256686 105256687 112637321 112637326 112637331 112638553 112638557 112639201 112639202 112639261 112639740 112639741 112639742 |
FEX: | 115236133 115236134 115236150 115236151 115237523 |
AROA: | 105683668 125499885 |
MCIX: | 123663296 123663419 |
PPOI: | 119109697 119110553 |
RSAN: | 119377657 119390491 |
CSCU: | 111625153 111627529 |
CEL: | CELE_Y42G9A.4(mvk-1) |
CBR: | CBG_21109(Cbr-mvk-1) |
BMY: | BM_BM6529(Bma-mvk-1) |
PMAX: | 117332956 117332970 |
RPHI: | 132735902 132736225 |
CSAT: | 104707052 104736766 104771212 |
BNA: | 106436597 111198056 111198505 125580785 125581861 125600811 |
MINC: | 123197506 123221641 |
HSYR: | 120115762 120178740 |
AHF: | 112755499 112755643 112756760 |
PCIN: | 129298995 129299838 |
QSA: | O6P43_007529 O6P43_011125 |
MSYL: | 126593342 126619049 |
MCHA: | 111011387 111018832 |
CMAX: | 111465579 111487302 111493596 |
CMOS: | 111444305 111447000 111450731 |
CPEP: | 111781542 111798415 111805143 |
HBR: | 110660269 110660320 110667490 |
MESC: | 110620146 110623597 |
PALZ: | 118044920 118060809 |
NTA: | 107766711 107815397 107826217 107829822 |
SSPL: | 121765029 121793434 121798901 121799693 |
SMIL: | 130996938 130996940 131019907 |
SHIS: | 125204219 125222626 |
CSIN: | 114298564 114313838 |
PSOM: | 113299757 113303572 |
TAES: | 101290664 123047441 123191075 |
MFLO: | 136462611 136466492 136475470 136475541 136487044 136548783 |
SITA: | 101761036 101779972 |
PVIR: | 120673356 120706983 |
ZOF: | 122020545 122024528 122030813 122033314 |
AOF: | 109820632 109828000 109850534 |
SMO: | SELMODRAFT_108013 SELMODRAFT_418055 SELMODRAFT_85880 |
CGR: | 2887740(GVI51_F03553) |
NCS: | NCAS_0C01100(NCAS0C01100) |
NDI: | NDAI_0K01160(NDAI0K01160) |
TPF: | TPHA_0G00700(TPHA0G00700) |
TBL: | TBLA_0D01180(TBLA0D01180) |
TDL: | TDEL_0A06630(TDEL0A06630) |
KAF: | KAFR_0B03180(KAFR0B03180) |
KNG: | KNAG_0J01960(KNAG0J01960) |
LBG: | 92205867(LODBEIA_P06710) |
CAL: | CAALFM_C109460WA(ERG12) |
YLI: | 2906793(YALI2_C00451g) |
NTE: | NEUTE1DRAFT144523(NEUTE1DRAFT_144523) |
SMP: | 10807000(SMAC4_03091) |
PBEL: | QC761_209280(ERG12) |
PPSD: | QC762_209280(ERG12) |
PPSP: | QC763_209280(ERG12) |
PPSA: | QC764_209280(ERG12) |
MTM: | MYCTH_66022 MYCTH_71219 |
SSCK: | SPSK_03625 SPSK_05171 |
TATV: | 25780492(TrAtP1_011547) |
TASP: | 36608199(TrAFT101_008579) |
MAW: | 19250358(ERG12_1) 90963128(ERG12_3) |
MBRN: | 26237981(ERG12_0) 26243648(ERG12_2) 26247579(ERG12_1) |
PCHM: | VFPPC_09849 VFPPC_17928 |
PLJ: | 28890460(PLICBS_009789) |
PTKZ: | JDV02_004757(ERG12) |
ALUC: | AKAW2_51249S(ERG12) |
TRG: | TRUGW13939_03774 TRUGW13939_09867 |
PTRR: | 6341198(PtrM4_065640) |
ZTR: | MYCGRDRAFT_73816(ERG12) |
PTM: | GSPATT00000330001 GSPATT00003653001 PTMB.192 |
PTI: | PHATRDRAFT_53929(MK) |
EHX: | EMIHUDRAFT_462458(MVK2) EMIHUDRAFT_468695(MVK1) |
LMAT: | 92511490(LSCM1_01357) |
LOI: | 92359091(LSCM4_03141) |
NGR: | NAEGRDRAFT_76883 NAEGRDRAFT_79135 |
ALIG: | NCTC10568_00310(galK_2) |
CBS: | COXBURSA331_A0721(mvk) COXBURSA331_A0722 |
CBD: | CBUD_0620(mvk) CBUD_0621 |
CBG: | CbuG_1394 CbuG_1395(mvk) |
CBC: | CbuK_1441 CbuK_1442(mvk) |
CEY: | CleRT_04140 CleRT_04150 |
CEA: | Z664_00895 Z664_00900 |
CEND: | EGQ50_00885 EGQ50_00890(mvk) |
CENO: | CEAn_00163 CEAn_00164 |
ALG: | AQULUS_04690(hddA) AQULUS_04700(galK) |
CEQ: | B1F76_00885 B1F76_00890 |
LWA: | SAMEA4504053_2293 SAMEA4504053_2445 |
HTR: | EPV75_09315 EPV75_09320 |
HMAR: | HVMH_0514 HVMH_0515 |
TCY: | Thicy_1412 Thicy_1413 |
TAO: | THIAE_09045 THIAE_09050 |
THIO: | AYJ59_04615 AYJ59_04620 |
TMH: | JX580_02680 JX580_02685 |
THIG: | FE785_08505(mvk) FE785_08510(mvk) |
TXA: | HQN79_03325 HQN79_03330 |
TLH: | NR989_08680(mvk) NR989_08685 |
TSE: | THMIRHAS_19660 THMIRHAS_19670 |
TZO: | THMIRHAT_05330 THMIRHAT_05340 |
MARS: | A8C75_06245 A8C75_06250 |
MGEO: | CFI10_03835 CFI10_03840(mvk) |
MSEC: | LN244_12890(mvk) LN244_12895 |
MRZ: | KDW95_09955 KDW95_09960 |
NCU: | F0U83_11840(mvk) F0U83_11845 |
NJP: | NEJAP_2667 NEJAP_2668 |
NIK: | F5I99_04675 F5I99_04680 |
AJP: | AMJAP_2615 AMJAP_2616 |
CHJ: | NCTC10426_00153 NCTC10426_01112 |
SUTR: | L0B52_04550 L0B52_04580 |
LAS: | CLIBASIA_04595 CLIBASIA_04600 |
LAT: | CGUJ_04595 CGUJ_04600 |
LAR: | lam_725(eRG12) lam_726 |
LAU: | G293_00040 G293_00045 |
RHM: | B5V46_13610 B5V46_13615 |
MYX: | QEG98_27235(mvk) QEG98_34380 |
PAUU: | E8A73_032575(mvk) E8A73_033635 |
SAQI: | AXG55_03860 AXG55_03870 |
SAX: | USA300HOU_0583(mvaK1) |
SUK: | SAA6008_00597(mvaK1) |
SUQ: | HMPREF0772_12598(mvk) |
SUX: | SAEMRSA15_05180(mvaK1) |
SUF: | SARLGA251_05250(mvaK1) |
SAUT: | SAI1T1_2004540(mvaK1) |
SAUJ: | SAI2T2_1004560(mvaK1) |
SAUK: | SAI3T3_1004550(mvaK1) |
SAUQ: | SAI4T8_1004540(mvaK1) |
SAUV: | SAI7S6_1004550(mvaK1) |
SAUW: | SAI5S5_1004510(mvaK1) |
SAUX: | SAI6T6_1004520(mvaK1) |
SAUY: | SAI8T7_1004550(mvaK1) |
SPIC: | SAMEA4384060_2278(mvaK1) |
SSIM: | SAMEA4384339_0538(mvaK1) |
LMOC: | LMOSLCC5850_0011(mvk) |
LMW: | LMOSLCC2755_0011(mvk) |
LMX: | LMOSLCC2372_0011(mvk) |
LMZ: | LMOSLCC2482_0011(mvk) |
LMON: | LMOSLCC2376_0011(mvk) |
LMOS: | LMOSLCC7179_0011(mvk) |
LMOO: | LMOSLCC2378_0011(mvk) |
LMOY: | LMOSLCC2479_0011(mvk) |
LMOT: | LMOSLCC2540_0011(mvk) |
LMOA: | LMOATCC19117_0011(mvk) |
SPZ: | M5005_Spy0682(mvaK1) |
SPYM: | M1GAS476_0741(mvaK1) |
SPH: | MGAS10270_Spy0740(mvaK1) |
SPI: | MGAS10750_Spy0774(mvaK1) |
SPJ: | MGAS2096_Spy0753(mvaK1) |
SPK: | MGAS9429_Spy0737(mvaK1) |
STG: | MGAS15252_0707(mvaK1) |
STX: | MGAS1882_0703(mvaK1) |
STZ: | SPYALAB49_000708(mvk) |
SNV: | SPNINV200_03430(mvaK1) |
SNC: | HMPREF0837_10679(mvk) |
SPNG: | HMPREF1038_00432(mvaK1) |
SPNE: | SPN034156_14340(mvaK1) |
SPNU: | SPN034183_03840(mvaK1) |
SPNM: | SPN994038_03720(mvaK1) |
SPNO: | SPN994039_03730(mvaK1) |
SSB: | SSUBM407_0260(mvaK1) |
SGG: | SGGBAA2069_c12570(mvk) |
SCP: | HMPREF0833_11234(mvk) |
SSAH: | HSISS4_00470(mvaK1) |
SVB: | NCTC12167_00590(mvk) |
SMEN: | SAMEA4412692_2090(mvaK1) |
SFER: | NCTC12278_01041(mvaK1) |
SCAI: | NCTC12191_01813(mvaK1) |
SPSU: | NCTC13786_02075(mvaK) |
SPOC: | NCTC10925_01062(mvaK) |
SAUP: | NCTC3168_01005(mvaK) |
SURN: | NCTC13766_00972(mvaK1) |
SVF: | NCTC3166_01743(mvaK) |
SMIE: | NCTC11169_00161(mvk) |
LPW: | LpgJCM5343_09160(mvk) |
LRU: | HMPREF0538_22184(mvk) |
LHIL: | G8J22_01433(galK_1) |
EFU: | HMPREF0351_10225(mvk) |
AUR: | HMPREF9243_0783(mvk) |
JDA: | BW727_101264(galK_2) |
AHK: | NCTC10172_00504(galK) |
MMAE: | MMARE11_31170(erg12) |
NBR: | O3I_007930 O3I_023295 O3I_033245 |
NAH: | F5544_04365(mvk) F5544_24685(mvk) |
NAD: | NCTC11293_04516(galK_1) |
SQZ: | FQU76_00340(mvk) FQU76_32120(mvk) FQU76_33400(mvk) |
SXT: | KPP03845_300049(galK) |
SCAJ: | O1G22_43445(mvk) O1G22_43840(mvk) |
PSEK: | GCM125_28640(mvaK1) |
PPC: | HMPREF9154_0776(mvk) |
ACIJ: | JS278_00857(galK_2) |
MSAG: | GCM10017556_12050(mvk) |
ANE: | ATCC27039_12780(mvk) |
ACAP: | MANAM107_01660(mvk) |
GVG: | HMPREF0421_21153(mvk) |
GVA: | HMPREF0424_0312(mvk) |
GVH: | HMPREF9231_0383(mvk) |
VBL: | L21SP4_02096 L21SP4_02097 |
TAER: | GT409_07790(mvk) GT409_07795 |
FOK: | KK2020170_04140(mvaK) |
FBU: | UJ101_01108(MVK|mvaK1) |
TMG: | US01_C0001G0068 US01_C0001G0069 |
MIB: | UY43_C0001G1158 UY43_C0001G1159 |
MJK: | N2V74_02515(mvk) N2V74_03345(mvk) |
HALQ: | Hrr1229_013100(mvk) |
HJT: | DVR14_17925(mvk) DVR14_22055(mvk) |
LOKI: | Lokiarch_22760(mvk) |
» show all
|
Reference |
1 |
Authors |
Hellig H, Popjak G. |
Title |
Studies on the biosynthesis of cholesterol. XIII. Phosphomevalonic kinase from liver. |
Journal |
J Lipid Res 2:235-243 (1961) |
Reference |
|
Authors |
LEVY HR, POPJAK G. |
Title |
Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver. |
Journal |
|
Reference |
3 |
Authors |
Markley K, Smallman E. |
Title |
Mevalonic kinase in rabbit liver. |
Journal |
Biochim Biophys Acta 47:327-335 (1961) |
Reference |
|
Authors |
TCHEN TT. |
Title |
Mevalonic kinase: purification and properties. |
Journal |
J Biol Chem 233:1100-3 (1958) |
Other DBs |
ExplorEnz - The Enzyme Database: | 2.7.1.36 |
ExPASy - ENZYME nomenclature database: | 2.7.1.36 |
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