| Entry |
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| Name |
fucokinase;
fucokinase (phosphorylating);
fucose kinase;
L-fucose kinase;
L-fucokinase;
ATP:6-deoxy-L-galactose 1-phosphotransferase;
ATP:L-fucose 1-phosphotransferase
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
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| Sysname |
ATP:beta-L-fucose 1-phosphotransferase
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| Reaction(IUBMB) |
ATP + L-fucose = ADP + beta-L-fucose 1-phosphate [RN: R03161]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Requires a divalent cation for activity, with Mg2+ and Fe2+ giving rise to the highest enzyme activity. Forms part of a salvage pathway for reutilization of L-fucose. Can also phosphorylate D-arabinose, but more slowly.
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| History |
EC 2.7.1.52 created 1972, modified 2004
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| Pathway |
| ec00051 | Fructose and mannose metabolism |
| ec00520 | Amino sugar and nucleotide sugar metabolism |
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| Orthology |
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| Genes |
» show all
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| Reference |
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| Authors |
Ishihara H, Massaro DJ, Heath EC. |
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| Title |
The metabolism of L-fucose. 3. The enzymatic synthesis of beta-L-fucose 1-phosphate. |
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| Journal |
J Biol Chem 243:1103-9 (1968) |
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| Reference |
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| Authors |
Butler W, Serif GS. |
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| Title |
Fucokinase, its anomeric specificity and mechanism of phosphate group transfer. |
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| Journal |
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| Reference |
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| Authors |
Park SH, Pastuszak I, Drake R, Elbein AD. |
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| Title |
Purification to apparent homogeneity and properties of pig kidney L-fucose kinase. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.7.1.52 |
| ExPASy - ENZYME nomenclature database: | 2.7.1.52 |
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