Entry |
|
Name |
deoxycytidine kinase;
deoxycytidine kinase (phosphorylating);
2'-deoxycytidine kinase;
Ara-C kinase;
arabinofuranosylcytosine kinase;
deoxycytidine-cytidine kinase
|
Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
 |
Sysname |
NTP:deoxycytidine 5'-phosphotransferase
|
Reaction(IUBMB) |
NTP + deoxycytidine = NDP + dCMP [RN: R02321]
|
Reaction(KEGG) |
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Substrate |
|
Product |
|
Comment |
Cytosine arabinoside can act as acceptor; all natural nucleoside triphosphates (except dCTP) can act as donors.
|
History |
EC 2.7.1.74 created 1972
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Pathway |
|
Orthology |
K15519 | deoxyadenosine/deoxycytidine kinase |
|
Genes |
» show all
 |
Reference |
|
Authors |
Durham JP, Ives DH. |
Title |
Deoxycytidine kinase. II. Purification and general properties of the calf thymus enzyme. |
Journal |
J Biol Chem 245:2276-84 (1970) |
Reference |
|
Authors |
Ives DH, Durham JP. |
Title |
Deoxycytidine kinase. 3. Kinetics and allosteric regulation of the calf thymus enzyme. |
Journal |
J Biol Chem 245:2285-94 (1970) |
Reference |
|
Authors |
Kessel D. |
Title |
Properties of deoxycytidine kinase partially purified from L1210 cells. |
Journal |
J Biol Chem 243:4739-44 (1968) |
Reference |
|
Authors |
Momparler RL, Fischer GA. |
Title |
Mammalian deoxynucleoside kinase. I. Deoxycytidine kinase: purification, properties, and kinetic studies with cytosine arabinoside. |
Journal |
J Biol Chem 243:4298-304 (1968) |
Other DBs |
ExplorEnz - The Enzyme Database: | 2.7.1.74 |
ExPASy - ENZYME nomenclature database: | 2.7.1.74 |
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