Entry
Name
glucosamine kinase;
glucosamine kinase (phosphorylating);
ATP:2-amino-2-deoxy-D-glucose-6-phosphotransferase;
aminodeoxyglucose kinase;
ATP:D-glucosamine phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:D-glucosamine 6-phosphotransferase
Reaction(IUBMB)
ATP + D-glucosamine = ADP + D-glucosamine 6-phosphate [RN:
R01961 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme is specific for glucosamine and has only a minor activity with D-glucose. Two unrelated enzymes with this activity have been described. One type was studied in the bacterium Vibrio cholerae, where it participates in a chitin degradation pathway. The other type has been described from actinobacteria, where it is involved in the incorporation of environmental glucosamine into antibiotic biosynthesis pathways. cf. EC
2.7.1.147 , ADP-specific glucose/glucosamine kinase.
History
EC 2.7.1.8 created 1961, modified 2014, modified 2020
Pathway
ec00520 Amino sugar and nucleotide sugar metabolism
Orthology
Genes
PATR : EV46_18395 EV46_18400
PATO : GZ59_37490 GZ59_37500
PCC : PCC21_035210 PCC21_035220
PCV : BCS7_17690 BCS7_17695
PWA : Pecwa_3676 Pecwa_3677
PPAR : A8F97_00285 A8F97_00290
PPOA : BJK05_12565 BJK05_12570
PBRA : B5S52_03860 B5S52_03865
PPUJ : E2566_17740 E2566_17745
PARI : I2D83_04180 I2D83_04185
PAQU : DMB82_0016850 DMB82_0016855
PVZ : OA04_37760 OA04_37770(gspK)
PPAV : LOZ86_17775 LOZ86_17780
PQU : IG609_016635 IG609_016640
PPOO : LW347_17795 LW347_17800
PACB : M9782_20000 M9782_20005
PCOA : PJ912_08105 PJ912_08110
PARL : PEC302110_32760 PEC302110_32770
PPEU : DUT67_03740 DUT67_03745
DDD : Dda3937_03083 Dda3937_03084
DDC : Dd586_3481 Dd586_3482
DZC : W909_16700 W909_16705
DSO : A4U42_05245 A4U42_05250
CED : LH89_09620 LH89_16355 LH89_16360
DFN : CVE23_18570 CVE23_18575
DDQ : DDI_0307 DDI_3501 DDI_3502
DAQ : DAQ1742_03768 DAQ1742_03769
DIC : Dpoa569_000648 Dpoa569_000649
DLC : O1Q98_14865 O1Q98_14870
DDA : Dd703_0709 Dd703_0710
VNI : VIBNI_A2828 VIBNI_B0086
VCY : IX92_02095 IX92_12735
VCT : JV59_01620 JV59_36615
VTU : IX91_02455 IX91_02760
VSR : Vspart_02944(gspK_1)
VKA : BTD91_03620 BTD91_09255
VLE : ISX51_04235 ISX51_09695
SCAA : TUM17387_28170(nagK)
SZH : K0H63_01570 K0H63_05125
THAT : H3N35_17940 H3N35_25035
TACT : SG35_018955 SG35_026065
TVD : SG34_002365 SG34_010155
PTN : PTRA_b0124 PTRA_b0730
PSEN : PNC201_07110(gspK1) PNC201_11730(gspK2)
PDJ : D0907_04165 D0907_06605 D0907_17135
PFLI : CTT31_07220 CTT31_12115
PMAZ : R5H13_07765 R5H13_12565
PSHO : KQ246_07475 KQ246_10295 KQ246_17890
AMAC : MASE_13860 MASE_19490
AMB : AMBAS45_03885 AMBAS45_04210 AMBAS45_14390
AMG : AMEC673_04105 AMEC673_14185
AMK : AMBLS11_04015 AMBLS11_13770
AAL : EP13_04220 EP13_14045
ALR : DS731_01615 DS731_18305
APEL : CA267_006520 CA267_013480
GPS : C427_0352 C427_4330 C427_4379
PMES : FX988_02742 FX988_02877
LAL : AT746_09745 AT746_16505 AT746_16950
CATE : C2869_07465 C2869_17275
SALH : HMF8227_01499(gspK)
SAGA : M5M_04360 M5M_07535
MTHD : A3224_04105 A3224_04735
MICC : AUP74_00061(gspK_1) AUP74_02805(gspK_3)
MAGA : Mag101_04425 Mag101_06230
MHYD : GTQ55_04860 GTQ55_07260
MPAF : R5R33_14140 R5R33_16195
PSAL : PSLF89_2955 PSLF89_754
RHEI : ATY27_06510 ATY27_18350
GAI : IMCC3135_01345(gspK_1)
ENW : MJO57_02615 MJO57_08625
CDIZ : CEDIAZO_03408(gspK)
CFU : CFU_2609(nagK2) CFU_2985(nagK1)
CARE : LT85_1579 LT85_1991
CPRA : CPter91_1545(nagK1) CPter91_3368(nagK2)
MLN : A9174_03445 A9174_29390
MOP : Mesop_0726 Mesop_5810
MAM : Mesau_00694 Mesau_05298
MHUA : MCHK_0762 MCHK_5840
MJR : EB229_03535 EB229_29970
MERD : EB233_03600 EB233_25980
MMEI : LRP31_03085 LRP31_30200
NKI : KW403_04315 KW403_09030
NRH : T8J41_05110 T8J41_10065
CHEA : PVE73_05395 PVE73_10095
AAK : AA2016_0481 AA2016_4795
AMIS : Amn_03250 Amn_16600
EAK : EKH55_3392 EKH55_5788
RLB : RLEG3_02545 RLEG3_25125
RLU : RLEG12_01070 RLEG12_24350
RTR : RTCIAT899_CH11655 RTCIAT899_PC03310
RGA : RGR602_CH02554 RGR602_PB00106
RJG : CCGE525_13175 CCGE525_31130
RHR : CKA34_15035 CKA34_22350
RBQ : J2J99_15275 J2J99_30415
RLN : J0663_02030 J0663_30185
RBAN : J2J98_14645 J2J98_27010
RRG : J3P73_17170 J3P73_35180
RLS : HB780_07835 HB780_18310
RAW : NE851_07465 NE851_26255
RHIB : I8E17_10130 I8E17_21945
NGL : RG1141_CH22790(gpsK) RG1141_CH41810 RG1141_PA08240
NGG : RG540_CH23630(gpsK) RG540_CH42330
NEO : CYG48_08820 CYG48_15645
NPM : QEO92_11950 QEO92_25370
BMEL : DK63_2490 DK63_3066
BMI : BMEA_B0488 BMEA_B1112
BMZ : BM28_B0489 BM28_B1097
BMG : BM590_B0488 BM590_B1093
BMW : BMNI_II0480 BMNI_II1060
BMEE : DK62_2333 DK62_2915
BMB : BruAb2_0708 BruAb2_1056
BMC : BAbS19_II06740 BAbS19_II10010
BAA : BAA13334_II00069 BAA13334_II01357
BABO : DK55_2689 DK55_3024
BABR : DO74_2530 DO74_3106
BABT : DK49_2549 DK49_3120
BABB : DK48_2773 DK48_3108
BABU : DK53_2122 DK53_2692
BABS : DK51_2175 DK51_2701
BABC : DO78_2364 DO78_2939
BSI : BS1330_II0510 BS1330_II1109
BSF : BSS2_II0490 BSS2_II1057
BSUI : BSSP1_II0471 BSSP1_II1308
BSUP : BSPT1_II0469 BSPT1_II1301
BSUV : BSPT2_II0472 BSPT2_II1303
BSUC : BSSP2_II0477 BSSP2_II1311
BMT : BSUIS_B0511 BSUIS_B1345
BSV : BSVBI22_B0509 BSVBI22_B1108
BSG : IY72_13170 IY72_16620
BCS : BCAN_B0514 BCAN_B1146
BSK : BCA52141_II0455 BCA52141_II1393
BOL : BCOUA_II0514 BCOUA_II1118
BCAR : DK60_2232 DK60_2803
BCAS : DA85_12940 DA85_15880
BPP : BPI_II1179 BPI_II496
BCET : V910_200178 V910_200734
BCEE : V568_200197 V568_200844
BVL : BF3285c2_0063 BF3285c2_0630 BF3285c2_0631
BRU : BFS01_13815 BFS01_15495
BRJ : BKD03_00370 BKD03_04190
OIN : IAR37_15075 IAR37_18535
BIO : BR141012304_20502 BR141012304_20886
OAN : Oant_3124 Oant_3545 Oant_4172
OAH : DR92_2942 DR92_3378 DR92_4076
BPSN : NIK97_12695 NIK97_17070
BRUC : LJ361_06480 LJ361_07930 LJ361_12590
OCR : HGK82_14050 HGK82_18745 HGK82_20205
OCL : GTN27_13990 GTN27_17660 GTN27_19120
LNE : FZC33_26820 FZC33_29035
CHEL : AL346_01455 AL346_23135
MMYR : MXMO3_03140 MXMO3_03201
MHAR : L1P08_06035 L1P08_09245
PLEO : OHA_1_02077(gspK_1) OHA_1_02908(gspK_2)
JAV : OXU80_07710 OXU80_15470
AEX : Astex_1697 Astex_2719 Astex_3615
ASTI : Q1W73_05570 Q1W73_10250
ASTD : ATDW_15400 ATDW_34240 ATDW_34870
SINL : DSM14862_03105(gspK)
AHT : ANTHELSMS3_01829(gspK)
FAP : GR316_11630 GR316_12825
SINR : O5O51_05000 O5O51_13465
NOR : FA702_18360 FA702_21265
SPHI : TS85_03730 TS85_12585
NAO : Y958_02520 Y958_27265 Y958_30040
ECOG : FIV45_02410 FIV45_17090
» show all
Taxonomy
Reference
Authors
BUEDING E, MACKINNON JA.
Title
Hexokinases of Schistosoma mansoni.
Journal
J Biol Chem 215:495-506 (1955)
Reference
Authors
Park JK, Wang LX, Roseman S
Title
Isolation of a glucosamine-specific kinase, a unique enzyme of Vibrio cholerae.
Journal
Sequence
Reference
Authors
Manso JA, Nunes-Costa D, Macedo-Ribeiro S, Empadinhas N, Pereira PJB.
Title
Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.8
ExPASy - ENZYME nomenclature database: 2.7.1.8
BRENDA, the Enzyme Database: 2.7.1.8