KEGG   ENZYME: 2.7.1.81Help
Entry
EC 2.7.1.81                 Enzyme                                 

Name
hydroxylysine kinase;
hydroxylysine kinase (phosphorylating);
guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
GTP:5-hydroxy-L-lysine O-phosphotransferase
Reaction(IUBMB)
GTP + 5-hydroxy-L-lysine = GDP + 5-phosphooxy-L-lysine [RN:R03378]
Reaction(KEGG)
Substrate
GTP [CPD:C00044];
5-hydroxy-L-lysine [CPD:C16741]
Product
GDP [CPD:C00035];
5-phosphooxy-L-lysine [CPD:C03366]
Comment
Both the natural 5-hydroxy-L-lysine and its 5-epimer act as acceptors.
History
EC 2.7.1.81 created 1972
Pathway
ec00310  Lysine degradation
ec01100  Metabolic pathways
Orthology
K18201  hydroxylysine kinase
Genes
HSA: 123688(HYKK)
PTR: 739839(HYKK)
PPS: 100990244(HYKK)
GGO: 101138799(HYKK)
PON: 100455708(HYKK)
NLE: 100580988(HYKK)
MCC: 710329(HYKK)
MCF: 102143817(HYKK)
CSAB: 103245249(HYKK)
RRO: 104677979(HYKK)
RBB: 108537974(HYKK)
CJC: 100386138(HYKK)
SBQ: 101034398(HYKK) 101049778
MMU: 235386(Hykk)
RNO: 300723(Hykk)
CGE: 100756410(Hykk)
NGI: 103726029(Hykk)
HGL: 101702212(Hykk)
CCAN: 109682392(Hykk)
OCU: 100338857(HYKK)
TUP: 102477505(HYKK)
CFA: 475133(HYKK)
AML: 100484023(HYKK)
UMR: 103660312(HYKK)
ORO: 101366491(HYKK)
FCA: 101085212(HYKK)
PTG: 102965109(HYKK)
AJU: 106988498(HYKK)
BTA: 530270(HYKK)
BOM: 102281469(HYKK)
BIU: 109575651(HYKK)
PHD: 102316903(HYKK)
CHX: 102183458(HYKK)
OAS: 101122555(HYKK)
SSC: 100155220(HYKK)
CFR: 102517400(HYKK)
CDK: 105087215(HYKK)
BACU: 103015933(HYKK)
LVE: 103074471 103091195(HYKK)
OOR: 101277172(HYKK)
ECB: 100060343(HYKK)
EPZ: 103560068(HYKK)
EAI: 106840831(HYKK)
MYB: 102242468(HYKK)
MYD: 102754822(HYKK)
HAI: 109381512(HYKK)
RSS: 109457947(HYKK)
PALE: 102877942(HYKK)
LAV: 100659263(HYKK)
TMU: 101357081
MDO: 100025929(HYKK)
SHR: 100925038(HYKK)
OAA: 100082548(HYKK)
GGA: 415358(HYKK)
MGP: 104912798(HYKK)
CJO: 107318567(HYKK)
ACYG: 106033771(HYKK)
TGU: 100225104(HYKK)
GFR: 102032372(HYKK)
FAB: 101812642(HYKK)
PHI: 102101087(HYKK)
PMAJ: 107209498(HYKK)
CCW: 104697460(HYKK)
FPG: 101924119(HYKK)
FCH: 102057217(HYKK)
CLV: 102084439(HYKK)
EGZ: 104130741(HYKK)
AAM: 106496428(HYKK)
ASN: 102385118(HYKK)
AMJ: 106737060(HYKK)
PSS: 102449467(HYKK)
CMY: 102929726(HYKK)
CPIC: 101945644(HYKK)
PVT: 110086836(HYKK)
PBI: 103058107(HYKK)
GJA: 107109147(HYKK) 107125426
XLA: 398833(hykk.L)
XTR: 549168(hykk)
NPR: 108792705(HYKK)
DRE: 559560(hykk.2) 559635(hykk.1)
SANH: 107679050(hykk)
SGH: 107551378
CCAR: 109073200 109073910(hykk)
IPU: 108270524(hykk)
AMEX: 103024473(hykk)
NCC: 104941681(hykk) 104952857
MZE: 101485107(hykk)
OLA: 101157673(hykk)
XMA: 102234172(hykk)
PRET: 103463464(hykk)
NFU: 107392750(hykk)
CSEM: 103394279(hykk)
HCQ: 109519117(hykk) 109522092
BPEC: 110160020(hykk)
SASA: 106574169(hykk)
ELS: 105025360(hykk)
SFM: 108938859(hykk)
LCM: 102345395(HYKK)
CMK: 103173518 103186056(hykk)
CIN: 100178748
SPU: 583471
DME: Dmel_CG31751(CG31751)
DSI: Dsimw501_GD24148(Dsim_GD24148)
MDE: 101898827
AAG: 5563704
AME: 725458
BIM: 100745553
BTER: 100644916
SOC: 105199942
AEC: 105153719
ACEP: 105626660
PBAR: 105428025
HST: 105182569
CFO: 105256163
LHU: 105669300
PGC: 109862498
NVI: 100122924
DPA: 109540663
NVL: 108562591
BMOR: 101742724
PMAC: 106717579
PRAP: 111001363
API: 100160754
DNX: 107171766
ZNE: 110828643
FCD: 110844701
TUT: 107371095
HMG: 101240165
MNG: MNEG_1285
 » show all
Taxonomy
Reference
1  [PMID:4621658]
  Authors
Hiles RA, Henderson LM.
  Title
The partial purification and properties of hydroxylysine kinase from rat liver.
  Journal
J Biol Chem 247:646-51 (1972)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.81
IUBMB Enzyme Nomenclature: 2.7.1.81
ExPASy - ENZYME nomenclature database: 2.7.1.81
BRENDA, the Enzyme Database: 2.7.1.81
CAS: 9073-58-9

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