KEGG ENZYME: 2.7.1.86

ENZYME: 2.7.1.86

Entry

EC 2.7.1.86                 Enzyme

Name

NADH kinase;
reduced nicotinamide adenine dinucleotide kinase (phosphorylating);
DPNH kinase;
reduced diphosphopyridine nucleotide kinase;
NADH kinase

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor

Sysname

ATP:NADH 2'-phosphotransferase

Reaction(IUBMB)

ATP + NADH = ADP + NADPH [RN:R00105]

Reaction(KEGG)

R00105

Substrate

ATP [CPD:C00002];
NADH [CPD:C00004]

Product

ADP [CPD:C00008];
NADPH [CPD:C00005]

Comment

CTP, ITP, UTP and GTP can also act as phosphate donors (in decreasing order of activity). The enzyme is specific for NADH. Activated by acetate.

History

EC 2.7.1.86 created 1976 (EC 2.7.1.96 created 1978, incorporated 1978)

Orthology

K19386

NADH kinase

Genes

SCE:	YPL188W(POS5)

SEUB:

DI49_5278

SPAO:

SPAR_P00870

AGO:	AGOS_AFL063W

ERC:

Ecym_2231

KLA:	KLLA0_E19097g

KMX:	KLMA_60357(POS5)

LTH:	KLTH0H04818g

VPO:	Kpol_1002p66

ZRO:	ZYRO0G08206g

CGR:	2888057(GVI51_G02761)

NCS:	NCAS_0H01000(NCAS0H01000)

NDI:	NDAI_0F02290(NDAI0F02290)

TPF:	TPHA_0J02240(TPHA0J02240)

TBL:	TBLA_0B05170(TBLA0B05170)

TGB:	HG536_0A01570

TDL:	TDEL_0G01590(TDEL0G01590)

KAF:	KAFR_0B06770(KAFR0B06770)

KNG:	KNAG_0M00410(KNAG0M00410)

ZMK:	HG535_0H03990

SLUD:

SCDLUD_001069

DHA:	DEHA2F02442g

PIC:	PICST_53028(POS5)

PGU:	PGUG_02264

SPAA:

SPAPADRAFT_62402

LEL:	PVL30_003853(POS5)

LBG:	92208375(LODBEIA_P31790)

CAL:	CAALFM_C307010WA(POS5)

CTP:	CTRG_05636

COT:	CORT_0C00330

CDU:	CD36_86940

CTEN:

18249978(POS5)

CLU:	CLUG_01758

CLUS:

A9F13_13g02101

CAUR:

CJI96_0004405

ASAU:

88175174(PUMCH_004112)

PPA:	PAS_chr1-4_0124

PKZ:	C5L36_0B06380

BNN:	FOA43_000516

BBRX:

BRETT_003129

OPA:	HPODL_01829

YLI:	2911693(YALI2_E00361g)

NCR:

NCU07742

NTE:	NEUTE1DRAFT128131(NEUTE1DRAFT_128131)

SMP:	10804274(SMAC4_05136)

PAN:	PODANSg8226

PBEL:

QC761_204330(POS5)

PPSD:

QC762_204330(POS5)

PPSP:

QC763_204330(POS5)

PPSA:

QC764_204330(POS5)

TTT:	THITE_2108082

MTM:	MYCTH_2301909

CTHR:

CTHT_0068550

RTHE:

98124801(VTJ83DRAFT_3745)

MGR:

MGG_05450

PPEI:

PpBr36_07909

PGRI:

PgNI_06607

TMN:	UCRPA7_5768

SSCK:

SPSK_07486

FGR:	FGSG_02072

FPU:	FPSE_05163

FPOA:

FPOAC1_002216

FVN:	FVRRES_02454

FVR:	FVEG_07531

FOX:	FOXG_04411

NHE:	NECHADRAFT_96953

FFC:	NCS54_01241000

FKR:	NCS57_01268400

FMU:	J7337_010465

TRE:	TRIREDRAFT_66294

TRR:	M419DRAFT_85812

TATV:

25777627(TrAtP1_010778)

TASP:

36613948(TrAFT101_009306)

MAW:	19249895(POS5_2)

MAJ:

MAA_05021

MBRN:

26242297(pos5)

PCHM:

VFPPC_07854

CMT:

CCM_04929

AMUS:

LMH87_007525

PLJ:	28883866(PLICBS_005171)

PTKZ:

JDV02_004070(POS5)

VAL:	VDBG_09505

VDA:	VDAG_04740

CHIG:

CH63R_13250

CDET:

87951487(CDEST_14987)

ELA:	UCREL1_9389

PFY:	PFICI_10766

SSL:	SS1G_12647

BFU:	BCIN_10g02880(Bcpos5)

MBE:

MBM_01005

PSCO:

LY89DRAFT_592310

GLZ:	GLAREA_11351

ANI:	ANIA_08837

AFM:	AFUA_5G05890

ACT:	ACLA_009150

NFI:	NFIA_037240

AOR:	AO090009000675

ANG:	An17g02020

AFV:	AFLA_010696

ALUC:

AKAW2_70790S(POS5)

ACHE:

ACHE_11186S(POS5)

APUU:

APUU_70413A(POS5)

PDP:	PDIP_22580

POU:	POX_f08338

TMF:	EYB26_004712

TRG:	TRUGW13939_07986

CIM:	CIMG_06228

CPW:	9695068(POS5)

URE:	UREG_04158

ABE:

ARB_07009

TVE:

TRV_06453

PBL:	PAAG_07352

PBN:	PADG_05852

AJE:	HCAG_03020

BGH:	BDBG_08528

PNO:	SNOG_16449

PTE:

PTT_12200

PTRR:

6338533(PtrM4_017020)

BZE:	COCCADRAFT_99845

BSC:	COCSADRAFT_289796

BOR:	COCMIDRAFT_2170

AALT:

CC77DRAFT_871504

ADAC:

96088833(ACET3X_008511)

ARAB:

EKO05_0003187

ZTR:	MYCGRDRAFT_74468

PFJ:	MYCFIDRAFT_215527

CBET:

CB0940_09899

BCOM:

BAUCODRAFT_575207

NPA:	UCRNP2_10170

TML:	GSTUM_00006557001

SPO:	2543173(pos5)

SOM:	SOMG_04611(pos5)

CNE:

CNC04760

CNB:

CNBC2410

CNG:	CNAG_02859

CGI:	CGB_C7070W

CDEU:

CNBG_3510

CDEC:

89987833(IAS62_001058)

CTEG:

91989018(I308_102160)

CBAS:

91982210(I312_102162)

CDEP:

91089745(L203_105536)

KMG:	30167539(I203_106451)

KNE:	92178255(IAR55_000996)

KDJ:	28964807(I303_101104)

KBI:	30207323(I302_104215)

KPIN:

30169368(I206_100326)

KSH:	87953120(IL334_000989)

KER:	91106249(V865_007448)

TMS:	TREMEDRAFT_41900

TASA:

A1Q1_00048

CCAC:

CcaHIS019_0504090(POS5)

TVS:	TRAVEDRAFT_132068

DSQ:	DICSQDRAFT_69048

PCO:	PHACADRAFT_163784

SHS:	STEHIDRAFT_169903

HIR:	HETIRDRAFT_120488

PSQ:	PUNSTDRAFT_105852

ADL:	AURDEDRAFT_71868

FME:	FOMMEDRAFT_73476

GTR:	GLOTRDRAFT_138750

RSX:	RhiXN_07224

LBC:	LACBIDRAFT_296215

CCI:	CC1G_01965

ABP:	AGABI1DRAFT99179(AGABI1DRAFT_99179)

ABV:	AGABI2DRAFT178464(AGABI2DRAFT_178464)

PCUB:

JR316_0001945

MRR:	Moror_1526

E1B28_010099

SCM:	SCHCO_02631517(SCHCODRAFT_02631517)

CPUT:

CONPUDRAFT_125605

SLA:	SERLADRAFT_463762

WSE:	WALSEDRAFT_60672

WIC:	J056_003330

UMA:	UMAG_04539

PFP:	PFL1_01506

SGRA:

EX895_002106

MGL:

MGL_0521

MRT:

MRET_2349

PGR:	PGTG_16175 PGTG_18830

PTRC:

PtA15_4A524 PtA15_6A737

PSTR:

Pst134EA_011616

MLR:	MELLADRAFT_73081

RIE:	OCT59_027011

PTM:	GSPATT00006279001 GSPATT00009606001

» show all

Reference

1 [PMID:4335000]

Authors

Griffiths MM, Bernofsky C.

Title

Purification and properties of reduced diphosphopyridine nucleotide kinase from yeast mitochondria.

Journal

J Biol Chem 247:1473-8 (1972)

Other DBs

ExplorEnz - The Enzyme Database:

2.7.1.86

IUBMB Enzyme Nomenclature:

2.7.1.86

ExPASy - ENZYME nomenclature database:

2.7.1.86

BRENDA, the Enzyme Database:

2.7.1.86

CAS:	62213-39-2

All links

Gene (89)   
   MGENES (39)   
   RefGene (50)   
Protein sequence (524)   
   UniProt (490)   
   SWISS-PROT (6)   
   RefSeq(pep) (26)   
   PDBSTR (2)   
DNA sequence (105)   
   RefSeq(nuc) (50)   
   GenBank (30)   
   EMBL (25)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   InterPro (4)   
   Pfam (2)   
All databases (725)   

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