KEGG   ENZYME: 2.7.11.18
Entry
EC 2.7.11.18                Enzyme                                 
Name
myosin-light-chain kinase;
[myosin-light-chain] kinase;
ATP:myosin-light-chain O-phosphotransferase;
calcium/calmodulin-dependent myosin light chain kinase;
MLCK;
MLCKase;
myosin kinase;
myosin light chain kinase;
myosin light chain protein kinase;
myosin light-chain kinase (phosphorylating);
smooth-muscle-myosin-light-chain kinase;
STK18
Class
Transferases;
Transferring phosphorus-containing groups;
Protein-serine/threonine kinases
Sysname
ATP:[myosin light chain] O-phosphotransferase
Reaction(IUBMB)
ATP + [myosin light chain] = ADP + [myosin light chain] phosphate [RN:R03150]
Reaction(KEGG)
R03150
Substrate
ATP [CPD:C00002];
myosin light chain [CPD:C01003]
Product
ADP [CPD:C00008];
myosin light chain phosphate [CPD:C03875]
Comment
Requires Ca2+ and calmodulin for activity. The 20-kDa light chain from smooth muscle myosin is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors, but more slowly.
History
EC 2.7.11.18 created 1986 as EC 2.7.1.117, transferred 2005 to EC 2.7.11.18
Orthology
K00907  myosin-light-chain kinase
Genes
HSA340156(MYLK4) 4638(MYLK) 85366(MYLK2) 91807(MYLK3)
PTR101057233(MYLK) 465143(MYLK3) 471840(MYLK4) 742591(MYLK2)
PPS100974667(MYLK3) 100978891(MYLK2) 100979422(MYLK) 100995666(MYLK4)
GGO101142619(MYLK3) 101143745(MYLK2) 101151517(MYLK) 101151667(MYLK4)
PON100171951(MYLK3) 100444714(MYLK4) 100452913(MYLK) 100453783(MYLK2)
NLE100585981(MYLK2) 100591151(MYLK) 100594745(MYLK4) 100604194 115831086(MYLK3)
MCC707361(MYLK4) 712830(MYLK2) 715422(MYLK) 716132(MYLK3)
MCF102122026(MYLK4) 102132754(MYLK3) 102145766(MYLK2)
MTHB126944161 126949090 126952526 126964202
CSAB103222295(MYLK4) 103228167(MYLK) 103232215(MYLK3) 103248051(MYLK2)
CATY105582238(MYLK2) 105589245(MYLK3) 105589789(MYLK) 105596420(MYLK4)
PANU101007177(MYLK4) 101012839(MYLK3) 101016979(MYLK) 101018714(MYLK2)
TGE112614388(MYLK3) 112619273(MYLK) 112623401(MYLK4) 112633275(MYLK2)
RRO104653717(MYLK2) 104655407(MYLK) 104655430(MYLK3) 104661238(MYLK4)
RBB108514260(MYLK4) 108517416(MYLK) 108524142(MYLK2) 108534775(MYLK3)
TFN117068620(MYLK2) 117083396(MYLK) 117086614(MYLK4) 117087736(MYLK3)
PTEH111524418(MYLK3) 111548207(MYLK2) 111548560(MYLK4)
CANG105507100(MYLK4) 105517988(MYLK) 105524711(MYLK2) 105525877(MYLK3)
CJC100391801(MYLK2) 100392653(MYLK3) 100392656(MYLK4) 100409440(MYLK)
SBQ101029220(MYLK) 101038668(MYLK2) 101049056(MYLK4) 101050910(MYLK3)
CSYR103256318(MYLK4) 103257292(MYLK3) 103258482(MYLK2)
MMUR105866079(MYLK2) 105873493(MYLK4) 105876221(MYLK3) 105879866(MYLK)
LCAT123622844(MYLK2) 123625139(MYLK3) 123630468(MYLK) 123638169(MYLK4)
PCOQ105806476(MYLK) 105816054(MYLK4) 105818088(MYLK3) 105827561(MYLK2)
OGA100945351(MYLK2) 100954101(MYLK3) 100955570(MYLK)
MMU107589(Mylk) 213435(Mylk3) 228785(Mylk2) 238564(Mylk4)
MCAL110290127(Mylk2) 110300419(Mylk3) 110308670(Mylk4) 110311174(Mylk)
MPAH110319274(Mylk2) 110329346(Mylk) 110334129(Mylk4) 110337577(Mylk3)
RNO100911165(Mylk4) 117558(Mylk2) 288057(Mylk) 291926(Mylk3)
MCOC116069762(Mylk3) 116081489(Mylk4) 116085852(Mylk) 116091182(Mylk2)
MUN110547228(Mylk) 110550095(Mylk2) 110552995(Mylk3) 110558635(Mylk4)
CGE100755963(Mylk2) 100756400(Mylk4) 100758406(Mylk) 100766446(Mylk3)
MAUA101827753(Mylk) 101835727(Mylk2) 101836507(Mylk4) 101843459(Mylk3)
PLEU114702188(Mylk4) 114704843(Mylk) 114705574(Mylk2) 114709967(Mylk3)
MORG121433988(Mylk4) 121447126(Mylk3) 121460317(Mylk2) 121461750(Mylk)
MFOT126487709 126501627 126507021 126512146
AAMP119802026(Mylk3) 119815079(Mylk2) 119817116(Mylk4) 119824616(Mylk)
NGI103731078(Mylk2) 103737011(Mylk4) 103741992(Mylk)
HGL101701713(Mylk4) 101704236(Mylk) 101712444(Mylk2)
CPOC100721558(Mylk4) 100724875(Mylk2) 100728232(Mylk3)
CCAN109677703 109691764(Mylk2) 109700226(Mylk4)
DORD105981620(Mylk2) 105985888(Mylk4) 105987974(Mylk) 106000844(Mylk3)
DSP122096833(Mylk) 122096857(Mylk3) 122108431(Mylk4) 122120488(Mylk2)
NCAR124966787 124978195 124989613 124992643
OCU100009051(MYLK2) 100348694 100353972
OPI101517477(MYLK3) 101526040(MYLK) 101526659(MYLK2) 101526925(MYLK4)
TUP102468205(MYLK3) 102476504(MYLK) 102489117(MYLK2) 102498032(MYLK4)
GVR103588665(MYLK) 103594036(MYLK2) 103596627(MYLK3) 103596703(MYLK4)
CFA475345(MYLK3) 477187(MYLK2) 488012(MYLK) 488190
CLUD112642441(MYLK3) 112659408(MYLK4) 112673771(MYLK2) 112677106(MYLK)
VVP112907401(MYLK4) 112909931(MYLK2) 112913506(MYLK) 112914947(MYLK3)
VLG121478392(MYLK2) 121481492(MYLK3) 121499771(MYLK4) 121500652(MYLK)
AML100469244(MYLK2) 100473453(MYLK4) 100474254(MYLK3) 100481263(MYLK)
UMR103665161(MYLK4) 103673818(MYLK3) 103674343(MYLK2) 103678824(MYLK)
UAH113252202(MYLK3) 113252350(MYLK) 113258196(MYLK2) 113264229(MYLK4)
UAR123776613(MYLK3) 123798683(MYLK2) 123801590(MYLK4) 123802103(MYLK)
ELK111141709 111154981 111156670 111157401
LLV125088621 125103043 125103257 125109534
MPUF101673442(MYLK3) 101673644(MYLK2) 101681427(MYLK4)
ORO101368074(MYLK4) 101370711(MYLK3) 101378973(MYLK) 101381609(MYLK2)
EJU114199360(MYLK3) 114199417(MYLK) 114220792(MYLK2) 114223891(MYLK4)
ZCA113916853(MYLK) 113926282(MYLK4) 113936659(MYLK3) 113937891(MYLK2)
MLX118007012(MYLK) 118011350(MYLK2) 118023826(MYLK3) 118027388(MYLK4)
NSU110579470(MYLK2) 110582708(MYLK) 110586782(MYLK4) 110593623(MYLK3)
LWW102737434 102744951 102745310 102750760(MYLK4)
FCA101088408(MYLK4) 101091744(MYLK3) 101095813(MYLK2)
PYU121012339(MYLK2) 121020417(MYLK4) 121036344(MYLK) 121045237(MYLK3)
PBG122490426(MYLK4) 122491527(MYLK) 122495091(MYLK3) 122496404(MYLK2)
LRUF124504387 124511824 124526284
PTG102951994(MYLK2) 102962607(MYLK3) 102968305(MYLK4) 102972928(MYLK)
PPAD109249481(MYLK4) 109266499(MYLK) 109270987(MYLK3) 109272590(MYLK2)
AJU106965987(MYLK3) 106976155(MYLK4) 106984088(MYLK) 106986013(MYLK2)
HHV120235452(MYLK2) 120237364(MYLK) 120238194(MYLK3) 120241448(MYLK4)
BTA338037(MYLK) 518025(MYLK4) 526379(MYLK3) 533378(MYLK2)
BOM102264349(MYLK4) 102269080(MYLK) 102275601(MYLK3) 102276600(MYLK2)
BIU109567347(MYLK2) 109572727(MYLK3) 109577322(MYLK4)
BBUB102395214(MYLK3) 102402899(MYLK) 102412646(MYLK4) 102415047(MYLK2)
BBIS104984516(MYLK) 104989914(MYLK2) 104991444(MYLK3) 104998013(MYLK4)
CHX102181454(MYLK4) 102181980(MYLK3) 102182147(MYLK2) 102190641(MYLK)
OAS101111897(MYLK2) 101113784(MYLK3) 105603910(MYLK4) 443334(MYLK)
ODA120868758(MYLK2) 120869929 120870611(MYLK) 120872918(MYLK3)
CCAD122421038(MYLK3) 122429898(MYLK4) 122444644(MYLK) 122448844(MYLK2)
SSC100157526(MYLK4) 100524288(MYLK2) 110260971(MYLK3) 396848(MYLK)
CFR102505869(MYLK2) 102511426(MYLK3) 102515628(MYLK4) 102518144(MYLK)
CBAI105065146(MYLK3) 105073583(MYLK2) 105079764(MYLK4) 105081637(MYLK)
CDK105086549(MYLK4) 105090282(MYLK) 105091178(MYLK3) 105100824(MYLK2)
VPC102527878(MYLK4) 102530698(MYLK2) 102531913(MYLK) 102532937(MYLK3)
BACU103005866(MYLK3) 103008421(MYLK) 103017148(MYLK2) 103020477(MYLK4)
LVE103077707(MYLK4) 103079981(MYLK2) 103083551(MYLK3) 103090456(MYLK)
OOR101275794(MYLK4) 101282343(MYLK) 101287286(MYLK3) 101289244(MYLK2)
DLE111165019(MYLK3) 111171109 111171669(MYLK) 111184432(MYLK2)
PCAD102982196(MYLK3) 102982293(MYLK2) 102982405(MYLK) 102984346(MYLK4)
PSIU116740421(MYLK2) 116744277(MYLK3) 116752864(MYLK) 116761512(MYLK4)
ECB100050092(MYLK4) 100053698(MYLK2) 100056559(MYLK3) 100070482(MYLK)
EPZ103547465(MYLK) 103548123(MYLK4) 103559162(MYLK2)
EAI106823711(MYLK) 106833720(MYLK2) 106842841(MYLK4) 106848229(MYLK3)
MYB102259949(MYLK2) 102262704(MYLK4)
MYD102755283(MYLK2) 102759237(MYLK) 102765242(MYLK4)
MMYO118663442(MYLK2) 118674227(MYLK3) 118675928(MYLK) 118677237(MYLK4)
MLF102416877(MYLK) 102427404(MYLK4) 102443301(MYLK2)
MNA107527759(MYLK2) 107535858(MYLK3) 107542256(MYLK4)
PKL118707748(MYLK2) 118719751(MYLK3) 118723823(MYLK4)
HAI109383050(MYLK3) 109384471(MYLK2) 109388085
DRO112296778(MYLK3) 112297606(MYLK4) 112303707(MYLK2) 112320512(MYLK)
SHON118985341(MYLK2) 118990733(MYLK) 119001158(MYLK3) 119003468(MYLK4)
AJM119036780(MYLK4) 119039481(MYLK) 119047724(MYLK2) 119049053(MYLK3)
PDIC114488355(MYLK3) 114490158(MYLK) 114496983(MYLK4) 114506860(MYLK2)
PHAS123806040(MYLK3) 123815386(MYLK2) 123820715(MYLK4) 123826812(MYLK)
MMF118617212(MYLK) 118618547(MYLK2) 118626541(MYLK4) 118639281(MYLK3)
RFQ117013453(MYLK) 117016156(MYLK2) 117026833(MYLK4) 117034912(MYLK3)
PALE102878549(MYLK3) 102890778(MYLK) 102891799(MYLK2) 102894361(MYLK4)
PGIG120586716(MYLK) 120603520(MYLK2) 120607743(MYLK4) 120617226(MYLK3)
PVP105288842(MYLK) 105301197(MYLK3) 105305528(MYLK2) 105307680(MYLK4)
RAY107512864(MYLK2) 107516607(MYLK4) 107518034(MYLK)
MJV108385316 108393093(MYLK2) 108396719(MYLK) 108402114(MYLK3)
TOD119249184(MYLK3) 119251054(MYLK4) 119253977(MYLK2) 119257453(MYLK)
SARA101547014(MYLK3) 101550939(MYLK) 101558259(MYLK2) 101558996(MYLK4)
LAV100656405(MYLK2) 100665634(MYLK4) 100677183(MYLK)
TMU101340959 101345850 101353011
ETF101647140(MYLK) 101647217(MYLK3) 101654866(MYLK2) 101660330(MYLK4)
DNM101424493(MYLK2) 101433020(MYLK3) 101433098(MYLK4)
MDO100015876(MYLK3) 100019648(MYLK) 100021377(MYLK4)
GAS123235311(MYLK3) 123235420(MYLK2) 123240591(MYLK4) 123242352(MYLK)
SHR100918090(MYLK4) 100925131(MYLK3)
PCW110196726(MYLK4) 110207445(MYLK3) 110208127(MYLK)
OAA100079091(MYLK4) 100091283(MYLK) 100092442(MYLK3)
GGA396356(MYLK2) 396445(MYLK) 415748(MYLK3) 420893(MYLK4) 428278(MYLKSML)
PCOC116227380(MYLK) 116227766(MYLK2) 116233855 116243997(MYLK3)
MGP100538449 100542497(MYLK2) 100543918(MYLK4) 100547989(MYLK) 100551067(MYLK3) 104914090
CJO107309576(MYLK4) 107316813(MYLK) 107319273(MYLK3) 107323244(MYLK2) 107325036
NMEL110388525 110393482(MYLK4) 110400604(MYLK) 110404229(MYLK3) 110408280(MYLK2)
APLA101793167(MYLK3) 101799935(MYLK4) 101800032 101803931(MYLK2)
ACYG106029897(MYLK) 106039596(MYLK3) 106046900 106047119(MYLK2) 106048980(MYLK4)
AFUL116485603(MYLK4) 116490524(MYLK) 116493811(MYLK3) 116495849(MYLK2) 116498329
TGU100218159(MYLK2) 100222880(MYLK4) 100226590(MYLK) 100232455(MYLK3) 115490676
LSR110468290(MYLK) 110469015(MYLK2) 110470711(MYLK4) 110475603 110475887(MYLK3)
SCAN103814310(MYLK) 103816608(MYLK3) 103818174(MYLK4) 103818839(MYLK2) 103821775
PMOA120497241(MYLK4) 120498294 120499105(MYLK) 120507140(MYLK2) 120508049(MYLK3)
OTC121331625(MYLK2) 121333829(MYLK3) 121337981(MYLK) 121340492(MYLK4)
PRUF121348636(MYLK2) 121348877(MYLK3) 121356511(MYLK) 121357753(MYLK4)
GFR102037734(MYLK4) 102037824(MYLK2) 102038683(MYLK3) 102044716(MYLK)
FAB101807258(MYLK) 101807804 101809550(MYLK3) 101813259(MYLK2) 101819869(MYLK4)
PHI102101059 102104582(MYLK2) 102106790(MYLK) 102111091(MYLK4) 102112254(MYLK3)
PMAJ107207555(MYLK) 107209810(MYLK3) 107213081(MYLK2) 107213960(MYLK4) 107215054
CCAE111923845(MYLK4) 111932252(MYLK) 111934649(MYLK3) 111938138(MYLK2) 111940063
CCW104687441(MYLK3) 104687839(MYLK2) 104694020(MYLK) 104698150(MYLK4) 104698538
CBRC103617564(MYLK2) 103618668(MYLK4) 103619680(MYLK) 103620204(MYLK3)
ETL114058107(MYLK) 114060388(MYLK3) 114063040(MYLK2) 114070606 114071985
ZAB102061280(MYLK3) 102064907(MYLK4) 102065718(MYLK2) 102070704(MYLK)
ACHL103804271 103805203(MYLK2) 103807396(MYLK3) 103810948(MYLK4)
FPG101910574 101917440(MYLK3) 101922032(MYLK2) 101922066 101922502(MYLK)
FCH102050025(MYLK) 102051042(MYLK2) 102051053 102058744(MYLK3)
CLV102088141 102093425(MYLK2) 102094050(MYLK4) 102095697(MYLK3)
EGZ104122823(MYLK4) 104125557(MYLK3) 104128132(MYLK) 104132337
NNI104011279(MYLK3) 104018366(MYLK2) 104018798(MYLK) 104018914 104021845(MYLK4)
PLET104622613(MYLK3) 104624388(MYLK4)
PCRI104033820(MYLK3) 104034150
PCAO104040821(MYLK3) 104045085 104048454
ACUN113476670(MYLK4) 113482370(MYLK) 113484301(MYLK3) 113489147
TALA104367590(MYLK4) 104367906(MYLK3) 104369093(MYLK) 116962832(MYLK2) 116963129
PADL103913791(MYLK3) 103919008(MYLK4) 103919603(MYLK) 103921929
AFOR103895407(MYLK) 103896855(MYLK3) 103898825(MYLK4) 103901834(MYLK2) 103906086
ACHC115339138(MYLK2) 115342719(MYLK) 115345195 115346654(MYLK3) 115353120(MYLK4)
HALD104317041(MYLK3) 104319310 104319374(MYLK)
HLE104828009 104832594(MYLK) 104833169(MYLK2) 104835366(MYLK4) 104842598(MYLK3)
AGEN126038782 126039981 126040469 126045851 126048575
GCL127012657 127018136 127020982 127023499
CCRI104156986(MYLK4) 104159486 104162514(MYLK) 104166608
CSTI104552519(MYLK3) 104557436
EHS104504197(MYLK) 104507658 104511995 104516899(MYLK3)
CMAC104478194 104481707(MYLK) 104483543
MUI104540473(MYLK3) 104541743(MYLK4) 104544526
FGA104075263 104077649 104079246(MYLK3)
GSTE104253127 104260501 104261154
LDI104342090(MYLK3) 104344516 104346534(MYLK) 104352220
MNB103770588(MYLK4) 103771017(MYLK3) 103773779
OHA104331215(MYLK4) 104335392(MYLK3) 104336300
NNT104405076 104407141(MYLK) 104407146(MYLK3) 104412795
DPUB104301438(MYLK2) 104303214(MYLK4) 104305786(MYLK3) 104309777(MYLK)
PGUU104462175(MYLK) 104462897 104467155
ACAR104521279 104524255(MYLK) 104532937
CPEA104385529(MYLK2) 104387305(MYLK) 104388580(MYLK3) 104391638(MYLK4)
AVIT104269714 104271005 104273126 104274243 104277033(MYLK3)
CVF104285296 104286656(MYLK4) 104288459(MYLK) 104293989(MYLK2) 104294452(MYLK3)
CUCA104055738(MYLK3) 104060871(MYLK2) 104064904 104066859(MYLK4) 104067687(MYLK)
TEO104371064(MYLK) 104374567(MYLK3) 104378966
BRHI104493704(MYLK3) 104496687 104497888 104498634(MYLK4)
AAM106482002(MYLK4) 106483357(MYLK3) 106495651 106497378(MYLK2) 106499178(MYLK)
AROW112961486(MYLK2) 112973819(MYLK)
NPD112949543(MYLK2) 112949847(MYLK3) 112960116(MYLK)
TGT104568585(MYLK2) 104573964(MYLK) 104575251(MYLK3) 104578838(MYLK4)
DNE112984366(MYLK3) 112987277(MYLK2) 112992025(MYLK4) 112994221(MYLK)
SCAM104142532(MYLK2) 104146129(MYLK4) 104146343(MYLK3) 104151131(MYLK)
ASN102369318(MYLK2) 102371849(MYLK3) 102381743(MYLK) 102384108(MYLK4) 102387857
AMJ102557905 102561520(MYLK) 102568638(MYLK3) 102574082(MYLK4)
CPOO109310558(MYLK3) 109313073(MYLK2) 109314959(MYLK4) 109322804(MYLK)
GGN109289569 109292519(MYLK2) 109300981(MYLK4) 109301415(MYLK)
PSS102448460(MYLK4) 102458914(MYLK3) 102461616(MYLK)
CMY102929389(MYLK4) 102929671(MYLK) 102943339(MYLK3) 102943755
CPIC101934934(MYLK4) 101935997(MYLK3) 101945225 101950238(MYLK2)
TST117869384 117873146(MYLK4) 117885275(MYLK) 117886013(MYLK2) 117886754(MYLK3)
CABI116816818(MYLK2) 116823503(MYLK3) 116832025 116834662 116834732(MYLK)
MRV120374867(MYLK) 120380179(MYLK2) 120384598(MYLK3) 120397649(MYLK4)
ACS100557929(mylk) 100559335(mylk3) 100562117(mylk2) 100567803(mylk4)
PVT110076324(MYLK3) 110083010(MYLK) 110086708(MYLK2) 110090626(MYLK4)
SUND121914150(MYLK3) 121918581(MYLK) 121929527(MYLK2) 121929958(MYLK4)
PBI103059391(MYLK3) 103060340(MYLK) 112540892
PMUR107284832(MYLK4) 107290115(MYLK3)
CTIG120297265(MYLK4) 120312141(MYLK3) 120317336(MYLK2) 120317501
TSR106543664(MYLK)
PGUT117657250(MYLK2) 117668851(MYLK) 117670916(MYLK3) 117672422(MYLK4)
VKO123020628(MYLK4) 123022348(MYLK3) 123027308(MYLK) 123036113(MYLK2)
PMUA114599828(MYLK2) 114600967(MYLK4) 114602252(MYLK3) 114603926(MYLK)
ZVI118086713(MYLK3) 118088799(MYLK2) 118090072 118091777(MYLK)
GJA107106205 107108885(MYLK3) 107113908(MYLK)
STOW125427209(MYLK) 125433536(MYLK2) 125438688(MYLK4) 125443835(MYLK3)
XLA108700969 108701256(mylk.L) 108701763(mylkl.L) 108702240(mylk.S) 108714133 108715487 108719107(mylk4.L) 108720081(mylk4.S)
XTR100489678(mylkl) 100497991(mylk4) 100498081(xkr7) 100498243(mylk3) 101730432(mylk)
NPR108785969 108787381(MYLK4) 108802964(MYLK3)
RTEM120917880(MYLK3) 120918827(MYLK2) 120940648(MYLK4) 120944282(MYLK)
BBUF120980692(MYLK3) 121001079(MYLK4) 121003374(MYLK2) 121005859 121008261(MYLK)
BGAR122920471(MYLK3) 122939426(MYLK4) 122940368 122941810(MYLK2) 122942078(MYLK)
DRE100003770(mylk5) 449707(mylk4b) 492576(mylkb) 558685(mylk2) 561635(mylk3) 566845(mylk4a) 569510(mylka)
SRX107708588 107711643 107721383 107721964 107729567 107732064 107734487 107745269 107748549 107756349 107757773
SANH107658462 107659202 107665331 107671556(mylk4) 107671735 107671840 107674172 107688847 107690728 107701711
SGH107549024 107555454 107555775 107559533 107562868 107564009 107565501(mylk4) 107572770 107583040 107591027 107598691 107602975
CCAR109059236 109060264 109092025 109092334(mylk) 109093406 109103271 109111828 109112004
CAUA113039623 113042580 113046086 113046155 113047399 113051686 113053508 113063158 113065586 113065611 113084862 113087671 113093730 113106176 113109161
PPRM120459737(mylka) 120462888(mylk2) 120487735 120487736(mylk4a) 120489224(mylk5) 120491329 120493275(mylk3) 120493339(mylk4b)
MAMB125250022(mylk4a) 125260668(mylk2) 125264921(mylk3) 125269878(mylka) 125274305(mylkb) 125276812(mylk5) 125277903(mylk4b)
IPU108256285(mylk5) 108257896(mylk4b) 108259589(mylk3) 108266375(mylka) 108268043(mylk4a) 108273224(mylkb) 108276275(mylk2)
PHYP113525255 113528426 113533962 113538345 113540796(mylk3) 113545325(mylk4) 113545533 113547292
SMEO124376699(mylk4b) 124379789(mylk3) 124382820(mylka) 124384219(mylkb) 124387808(mylk4a) 124396657(mylk5) 124398715(mylk2)
TFD113634351(mylk4b) 113634552(mylkb) 113635249(mylk2) 113652221(mylk5) 113654347(mylka) 113660635(mylk3) 113662245(mylk4a)
AMEX103024505(mylk3) 103026233 103031137 103034955 103036671 103040564 103046799
EEE113570573 113574000 113580203 113583782 113587239 113588166 113588908(mylk3)
TRU101062352(mylk4) 101070888 101072200
TNGGSTEN00016215G001 GSTEN00022034G001
LCO104925897 104931540 104932056 104932396 104939112(mylk)
NCC104941115 104943457 104959010
CGOB115005974(mylk) 115006602 115011595 115022891
ELY117247106(mylk4b) 117251242(mylka) 117268957(mylk5) 117272282(mylk4a)
EFO125879351(mylk5) 125895818(mylk4b) 125899813(mylka) 125902487(mylk4a)
PLEP121951941(mylk4a) 121956704(mylk5) 121963547(mylk4b)
SLUC116038187(mylk4b) 116046022(mylk4a) 116059339(mylk5) 116064213(mylkb)
ECRA117950394(mylk4b) 117954407(mylk4a) 117957953(mylk5)
ESP116695568(mylk4) 116699211 116702937
PFLV114561233(mylk4) 114565381 114568996
GAT120816425 120824084(mylk4b) 120827945(mylk5) 120833692(mylkb)
PPUG119209229(mylk4a) 119217141(mylk4b) 119220388(mylk5) 119228971(mylkb)
MSAM119892236(mylk5) 119900283(mylk4b) 119902037(mylk4a) 119903747
CUD121503777(mylk5) 121512603(mylk4b) 121519648(mylk4a) 121522726(mylka)
ALAT119010884(mylk4a) 119014215(mylk5) 119025568(mylka) 119029312(mylk4b)
MZE101471947 101477846 101479888 101480150
ONL100690170 100694458 100698528(mylk4) 100704504 100704574
OAU116312478(mylk5) 116314400(mylk4b) 116318706(mylk4a) 116327386(mylka)
OLA101163967(mylk4) 101167024(mylk) 101171778 101171917
OML112138131(mylkb) 112146941(mylk5) 112147476(mylk4a) 112150925(mylk4b)
XMA102217469 102221101(mylk) 102231025 102231065(mylk4)
XCO114146754 114148756(mylk) 114151595(mylk4) 114160258
XHE116721924 116723452(mylk) 116726501(mylk4) 116736178
PRET103461832(mylk) 103463388 103469431 103479657 103481492
PFOR103135800 103135802 103142212 103151108(mylk4) 103153922(mylk)
PLAI106939360(mylk) 106952517(mylk4) 106952625 106960651
PMEI106912005 106914417 106916097(mylk) 106929696 106931036
GAF122822561(mylk5) 122837983(mylk4b) 122839732(mylka) 122841247
CVG107090039 107091785 107095545 107095655
CTUL119777375(mylkb) 119778873(mylk5) 119787700(mylk4b) 119795685(mylk4a)
GMU124863206 124865037(mylk5) 124870315(mylk4a) 124871629(mylka) 124873397(mylk4b)
NFU107378449 107383904 107393068 107395143(mylk)
KMR108239577(mylk4a) 108243578(mylk4b) 108243749(mylk5) 108251559
ALIM106524197 106528162 106530234(mylk) 106533840(mylk4)
NWH119407645(mylk4b) 119414202(mylk4a) 119419486(mylkb) 119421243(mylk5)
AOCE111568706 111573396(mylk4) 111576420
MCEP124998363(mylk5) 125009757(mylk4b) 125011146(mylk4a)
CSEM103392366(mylk) 103393163 103396270(mylk4)
POV109633942 109637330 109639205(mylk4)
SSEN122767287(mylk4a) 122780933(mylk4b) 122785605(mylk5) 122786945
HHIP117754929 117760149(mylk4b) 117766548(mylk5) 117778656(mylk4a)
HSP118117702(mylk4a) 118120002(mylka) 118120958(mylk4b) 118123951(mylk5)
LCF108879600(mylk4b) 108883405(mylk4a) 108895289 108901089(mylk5) 108901722
SDU111217682 111227561 111230430 111231110
SLAL111647650(mylk) 111660594 111661096 111671734
XGL120788222(mylk5) 120791078(mylk4b) 120798572(mylk4a) 120801368
HCQ109513812 109517037(mylk) 109521191 109525485
BPEC110158772(mylk) 110159535 110167799 110172296(mylk4)
MALB109957741 109961257(mylk4) 109964253 109970425(mylk)
BSPL114845084(mylk4a) 114847608 114854403(mylk4b) 114860007(mylk5)
SASA106560377 106562001 106566930 106569150 106581830 106584199 106586160 106587297 106599743 106601032 106607302
STRU115156095 115157147 115158633 115160690 115167428 115168262 115169625 115171123 115192295 115198091 115202922
OTW112222068(mylk2) 112225163 112225996(mylk5) 112226830 112234141 112249079 112250079 112251616 112258667 112260620 112263547
OMY110486267 110492284 110501531 110506364 110508620 110520040 110521751 110524657(mylk4b) 110526266 110530443 110538202
OGO123999084 124009787 124015533 124017967 124033863 124035849(mylk3) 124038702 124041768 124042085 124043813 124045781(mylk2)
ONE115102217 115102984 115104134 115108228 115108605 115112123 115113535 115114530 115139762 115145396
SALP111969255 111971173 111974136 111974361 111976280 111979255 111980444 111980481
SNH120020293 120025069 120034069 120036028 120046139 120051888 120054301 120055314(mylk4a) 120058222 120060728(mylk2) 120064442
CCLU121533886(mylk4b) 121534442(mylk4a) 121536678 121540038 121545524 121548320 121551681 121551734 121581322 121582329
ELS105013359 105013822 105019245 105026354(mylk3) 105026404 109614625(mylk)
SFM108926394 108928141 108929005 108937818(mylk3) 108939199(mylk4) 108941557 108942076
PKI111839803(mylk2) 111847736(mylk3) 111850056 111854340 111856005 111858342
AANG118210822(mylk2) 118214168(mylka) 118214811 118220996(mylk5) 118225122(mylk4b) 118227419 118234506(mylk4a)
LOC102682466(mylk3) 102685356(mylk2) 102686027 102689935(mylk4) 102697050(mylk)
PSPA121296189 121297790 121301925(mylk5) 121313105 121313945 121319393 121322302 121323021 121326024
ARUT117394608 117408899 117424756 117425952 117426995 117430381 117433415(mylk5) 117964469
PSEX120517084(mylk5) 120529538 120531737(mylka) 120535353(mylk3) 120538383
LCM102346967(MYLK3) 102352251
CMK103176059(mylk3) 103176418 103188646(mylk4a)
RTP109910570 109928019 109934886(mylk3)
BFO118405515 118405516 118405520 118405888 118414661
BBEL109464930 109471814 109486974
CIN100176083 100177233
SCLV120332930 120338419 120341953
SPU581963
APLC110985015
SKO100313660
DMEDmel_CG42347(sqa)
DPO6898797
DMN108159863 117193338
DGR6569001
CCAT101449028
BOD106614432
RZE108360497
SCAC106085866
LSQ119613286
HIS119655348
AGAAgaP_AGAP006746
ACOZ120947284 120950144 120957371
AARA120898762 120900909
ASTE118504535 118506138
AAG5566696
AALB109425849 115254206
CQUCpipJ_CPIJ005740 CpipJ_CPIJ012235
CPII120418481 120423882
CNS116347317
BCOO119070724
AME413190
ACER108001692
ALAB122719151
BIM100741566
BBIF117214693
BVK117233202
BVAN117166615
BTER100649174
BPYO122568737
MGEN117221146
NMEA116429762
CGIG122399422
PCF106790573
PFUC122513304
VPS122637041
NVI100118913
TPRE106659804
CGLO123263504
FAS105263396
DAM107042590
AGIF122855096
CCIN107273710
TCA659444
LDC111507951
MSEX115449670 119190261
NIQ126776786
PXU106120759
PRAP110996706
PBX123711378
PNAP125051567
ZCE119837503
CCRC123701217
TNL113500367
SLIU111349349 111354303
OFU114361676
CFEL113384664
API100163829
RMD113552034
BTAB109031131
CLEC106664694
HHAL106683752
NLU111052189
FOC113206234
TPAL117645515 117653473
CSEC111862018
SGRE126281583
DMK116917201
PVM113830372
PJA122253882
PCHN125033960 125033961
PCLA123763320
PTRU123499583
EAF111697244 111701334 111701340 111704177 111705908 111714020 111716464
LSM121113815 121114266 121115018
PPOI119108301 119108308
ISCIscW_ISCW020494
RSAN119383249
VDE111251098
VJA111272050
TUT107363672
DPTE113799848
CSCU111630964
CELCELE_ZC373.4(mlck-1)
CBRCBG_01967
LOALOAG_03589
NAINECAME_00034
LGILOTGIDRAFT_235177
BGT106052435 106072218
GAE121387359
HRF124110647 124141596 124149236
HRJ124281675 124281676
PMAX117317873 117344318
MMER123536661 123537837
OBI106880214
LAK106163548
ATEN116299105
PFAPF3D7_1423600
PREIPRSY57_1422900
PGABPGSY75_1423600
PYOPY17X_1021700
PCBPCHAS_1020600
PBEPBANKA_1019800
PVVPVVCY_1002470
PVXPVX_085300
 » show all
Reference
1  [PMID:6894756]
  Authors
Adelstein RS, Klee CB.
  Title
Purification and characterization of smooth muscle myosin light chain kinase.
  Journal
J Biol Chem 256:7501-9 (1981)
Reference
2  [PMID:156362]
  Authors
Hathaway DR, Adelstein RS.
  Title
Human platelet myosin light chain kinase requires the calcium-binding protein calmodulin for activity.
  Journal
Proc Natl Acad Sci U S A 76:1653-7 (1979)
DOI:10.1073/pnas.76.4.1653
Reference
3  [PMID:4853304]
  Authors
Pires E, Perry SV, Thomas MA.
  Title
Myosin light-chain kinase, a new enzyme from striated muscle.
  Journal
FEBS Lett 41:292-6 (1974)
DOI:10.1016/0014-5793(74)81232-9
Reference
4  [PMID:3881420]
  Authors
Nunnally MH, Rybicki SB, Stull JT.
  Title
Characterization of chicken skeletal muscle myosin light chain kinase. Evidence for muscle-specific isozymes.
  Journal
J Biol Chem 260:1020-6 (1985)
Reference
5  [PMID:3897230]
  Authors
Edelman AM, Takio K, Blumenthal DK, Hansen RS, Walsh KA, Titani K, Krebs EG.
  Title
Characterization of the calmodulin-binding and catalytic domains in skeletal muscle myosin light chain kinase.
  Journal
J Biol Chem 260:11275-85 (1985)
Reference
6  [PMID:12390014]
  Authors
Mal TK, Skrynnikov NR, Yap KL, Kay LE, Ikura M.
  Title
Detecting protein kinase recognition modes of calmodulin by residual dipolar couplings in solution NMR.
  Journal
Biochemistry 41:12899-906 (2002)
DOI:10.1021/bi0264162
Reference
7  [PMID:10231558]
  Authors
Sobieszek A.
  Title
Enzyme kinetic characterization of the smooth muscle myosin phosphorylating system: activation by calcium and calmodulin and possible inhibitory mechanisms of antagonists.
  Journal
Biochim Biophys Acta 1450:77-91 (1999)
DOI:10.1016/S0167-4889(99)00038-5
Reference
8  [PMID:9054394]
  Authors
Sobieszek A, Borkowski J, Babiychuk VS.
  Title
Purification and characterization of a smooth muscle myosin light chain kinase-phosphatase complex.
  Journal
J Biol Chem 272:7034-41 (1997)
DOI:10.1074/jbc.272.11.7034
Reference
9  [PMID:10098974]
  Authors
Fujita K, Ye LH, Sato M, Okagaki T, Nagamachi Y, Kohama K.
  Title
Myosin light chain kinase from skeletal muscle regulates an ATP-dependent interaction between actin and myosin by binding to actin.
  Journal
Mol Cell Biochem 190:85-90 (1999)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.11.18
IUBMB Enzyme Nomenclature: 2.7.11.18
ExPASy - ENZYME nomenclature database: 2.7.11.18
BRENDA, the Enzyme Database: 2.7.11.18
CAS: 51845-53-5

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