KEGG   ENZYME: 2.7.11.2
Entry
EC 2.7.11.2                 Enzyme                                 

Name
[pyruvate dehydrogenase (acetyl-transferring)] kinase;
PDH kinase;
PDHK;
PDK;
PDK1;
PDK2;
PDK3;
PDK4;
pyruvate dehydrogenase kinase;
pyruvate dehydrogenase kinase (phosphorylating);
pyruvate dehydrogenase kinase activator protein;
STK1
Class
Transferases;
Transferring phosphorus-containing groups;
Protein-serine/threonine kinases
Sysname
ATP:[pyruvate dehydrogenase (acetyl-transferring)] phosphotransferase
Reaction(IUBMB)
ATP + [pyruvate dehydrogenase (acetyl-transferring)] = ADP + [pyruvate dehydrogenase (acetyl-transferring)] phosphate [RN:R03449]
Reaction(KEGG)
R03449
Substrate
ATP [CPD:C00002];
[pyruvate dehydrogenase (acetyl-transferring)] [CPD:C01256]
Product
ADP [CPD:C00008];
[pyruvate dehydrogenase (acetyl-transferring)] phosphate [CPD:C01293]
Comment
The enzyme has no activating compound but is specific for its substrate. It is a mitochondrial enzyme associated with the pyruvate dehydrogenase complex in mammals. Phosphorylation inactivates EC 1.2.4.1, pyruvate dehydrogenase (acetyl-transferring).
History
EC 2.7.11.2 created 1978 as EC 2.7.1.99, transferred 2005 to EC 2.7.11.2
Orthology
K00898  pyruvate dehydrogenase kinase 2/3/4
K12077  pyruvate dehydrogenase kinase isoform 1
Genes
HSA: 5163(PDK1) 5164(PDK2) 5165(PDK3) 5166(PDK4)
PTR: 459743(PDK1) 468402(PDK2) 472448(PDK4) 740576(PDK3)
PPS: 100968174(PDK1) 100970620(PDK4) 100992308(PDK2) 100995647(PDK3)
GGO: 101129032(PDK2) 101143387(PDK3) 101149286(PDK4) 101150048(PDK1)
PON: 100174113(PDK2) 100435148(PDK4) 100442853(PDK1) 100462571(PDK3)
NLE: 100597085(PDK2) 100598085(PDK3) 100601990(PDK1) 100605243(PDK4)
MCC: 697772(PDK1) 698726(PDK4) 699394(PDK3) 704169(PDK2)
MCF: 101867293(PDK2) 102118837(PDK3) 102119067(PDK4) 102132161(PDK1)
CSAB: 103217325(PDK1) 103226523(PDK4) 103231727(PDK3) 103242950(PDK2)
CATY: 105574610(PDK3) 105579448(PDK2) 105579807(PDK1) 105592197(PDK4)
PANU: 101000103(PDK4) 101003598(PDK2) 101007312(PDK3) 101026361(PDK1)
RRO: 104654150(PDK3) 104656590(PDK4) 104673517(PDK1) 104680263(PDK2)
RBB: 108513535(PDK4) 108516442(PDK2) 108522274(PDK1) 108524111(PDK3)
TFN: 117067209(PDK2) 117072465(PDK4) 117074293(PDK3) 117094853(PDK1)
CJC: 100386396(PDK2) 100388325(PDK3) 100402844(PDK1) 100407216(PDK4)
SBQ: 101037963(PDK1) 101038610(PDK3) 101048009(PDK2) 101049325(PDK4)
MMUR: 105867287(PDK4) 105880731(PDK1) 105882342(PDK3) 105885105(PDK2)
MMU: 18604(Pdk2) 228026(Pdk1) 236900(Pdk3) 27273(Pdk4)
MCAL: 110286641(Pdk3) 110296681(Pdk4) 110305050(Pdk2) 110312693(Pdk1)
MPAH: 110313531(Pdk3) 110317019(Pdk4) 110318417(Pdk1) 110331436(Pdk2)
RNO: 116551(Pdk1) 296849(Pdk3) 81530(Pdk2) 89813(Pdk4)
MCOC: 116078985(Pdk2) 116086802(Pdk3) 116090302(Pdk1) 116098549(Pdk4)
MUN: 110551207(Pdk2) 110559643(Pdk4) 110564184(Pdk3) 110565621(Pdk1)
CGE: 100751145 100758762(Pdk2) 100763413(Pdk4) 100770270(Pdk3) 100774056(Pdk1)
PLEU: 114692903(Pdk2) 114693453(Pdk4) 114701563(Pdk3) 114704478(Pdk1)
NGI: 103725230(Pdk4) 103725376(Pdk3) 103728651 103738377(Pdk2) 103751806(Pdk1)
HGL: 101698433(Pdk4) 101699582(Pdk3) 101699994(Pdk2) 101705587(Pdk1)
CCAN: 109691403(Pdk2) 109697144(Pdk3) 109699522(Pdk1) 109701002(Pdk4)
OCU: 100348343(PDK2) 100351323(PDK1) 100351580(PDK4) 100352037(PDK3)
TUP: 102468786(PDK4) 102469133(PDK2) 102483149(PDK3) 102499515(PDK1)
CFA: 476828(PDK1) 478801 482310(PDK4) 491075(PDK2)
VVP: 112916403(PDK1) 112917852(PDK2) 112919100(PDK3) 112923906(PDK4)
VLG: 121472624(PDK2) 121474516(PDK4) 121482752(PDK3) 121501706(PDK1)
AML: 100464908(PDK4) 100466029(PDK3) 100476739(PDK2) 100483652(PDK1)
UMR: 103658746(PDK4) 103659566(PDK1) 103660465(PDK2) 103668186(PDK3)
UAH: 113242221(PDK3) 113250772(PDK1) 113260367(PDK4) 113265612(PDK2)
ORO: 101362728(PDK3) 101367021(PDK2) 101370661(PDK4) 101383119(PDK1)
ELK: 111144206 111147260 111150441 111151349
MPUF: 101683023(PDK1) 101684654(PDK2) 101685847(PDK4) 101689674(PDK3)
EJU: 114201172(PDK2) 114221329(PDK4) 114223594(PDK3) 114225916(PDK1)
MLX: 118006436 118006464 118007806(PDK3) 118012327(PDK1) 118020787(PDK4) 118024775(PDK2)
FCA: 101092256(PDK4) 101092705(PDK1) 101095314(PDK3) 101100013(PDK2)
PTG: 102948846(PDK3) 102951784 102960301(PDK1) 102963206(PDK2) 102969030(PDK4)
PPAD: 109247310(PDK2) 109249360(PDK3) 109263716(PDK4) 109273020(PDK1)
AJU: 106970005(PDK4) 106985184(PDK2) 106986815(PDK3) 106987925(PDK1)
HHV: 120229146(PDK2) 120234392(PDK4) 120236402(PDK1) 120248768(PDK3)
BTA: 507367(PDK4) 510841(PDK3) 524075(PDK2) 528655(PDK1)
BOM: 102264999(PDK4) 102265648(PDK1) 102266253(PDK2) 102275065(PDK3)
BIU: 109555405(PDK3) 109558225(PDK4) 109566453(PDK1) 109573763(PDK2)
BBUB: 102390883(PDK2) 102394745(PDK3) 102413185(PDK4) 102416388(PDK1)
CHX: 102180838(PDK3) 102185217(PDK2) 102186251(PDK1) 102190015(PDK4)
OAS: 101108725(PDK3) 101108929(PDK2) 101113205(PDK1) 101117752(PDK4)
ODA: 120854929(PDK1) 120867335(PDK2) 120877971(PDK4) 120882623(PDK3)
SSC: 100153858(PDK3) 100286778(PDK4) 100286871(PDK1) 100516037(PDK2)
CFR: 102508070(PDK2) 102511071(PDK3) 102518730(PDK4) 102518782(PDK1)
CDK: 105088722(PDK4) 105091095(PDK1) 105103897(PDK3) 105104826(PDK2)
BACU: 103000815(PDK4) 103007993 103016999(PDK1) 103018751(PDK2)
LVE: 103072788(PDK2) 103073094(PDK4) 103073975(PDK3) 103078387(PDK1)
OOR: 101271748(PDK1) 101279937(PDK2) 101286339(PDK4) 101288876(PDK3)
DLE: 111166477(PDK2) 111167510(PDK3) 111172870(PDK1) 111181307(PDK4)
PCAD: 102979242(PDK4) 102982880(PDK2) 102983475(PDK3) 102993902(PDK1)
ECB: 100052078(PDK4) 100060791(PDK3) 100064091(PDK1) 100147514(PDK2)
EPZ: 103543124 103551054(PDK2) 103553122(PDK1) 103555010(PDK4)
EAI: 106824116(PDK3) 106826450(PDK2) 106834715(PDK1) 106838924(PDK4)
MYB: 102251531(PDK4) 102255458(PDK3) 102259213(PDK2) 102262215(PDK1)
MYD: 102767099(PDK1) 102774306(PDK3) 102775297(PDK2) 102775518(PDK4)
MMYO: 118653855(PDK3) 118661163(PDK1) 118666200(PDK4) 118671292(PDK2) 118671355
MNA: 107531030(PDK1) 107534264(PDK3) 107539176(PDK2) 107541747(PDK4)
HAI: 109372242(PDK3) 109380767(PDK2) 109390399(PDK1) 109393138(PDK4)
DRO: 112305775(PDK1) 112313227(PDK3) 112316178(PDK2) 112319795(PDK4)
SHON: 118978115(PDK2) 118985702(PDK1) 118987339(PDK4) 118997065(PDK3)
AJM: 119047363(PDK4) 119047489(PDK3) 119052659(PDK2) 119053640(PDK1)
MMF: 118619928(PDK4) 118625263(PDK1) 118635080(PDK2) 118635694(PDK3)
PALE: 102880150(PDK4) 102883688(PDK1) 102885302(PDK2) 102888523(PDK3)
RAY: 107498344(PDK3) 107503332(PDK4) 107505192(PDK1) 107517591(PDK2)
MJV: 108385121(PDK2) 108390609(PDK3) 108391482(PDK1) 108406227(PDK4)
LAV: 100655808(PDK1) 100670251 100671485(PDK3) 100674220(PDK4)
TMU: 101341826 101355780 101357823 101360007
MDO: 100010271(PDK3) 100017644(PDK4) 100022514(PDK2) 100029831 100617164(PDK1)
SHR: 100924143(PDK2) 100924902(PDK3) 100932777(PDK1) 100934205(PDK4)
PCW: 110210803(PDK3) 110211577(PDK1) 110215793(PDK2) 110217579(PDK4)
OAA: 100084173(PDK1) 100088087(PDK4) 100090199(PDK2) 103170840(PDK3)
GGA: 107050147(PDKI2) 418595(PDK3) 420570(PDK4) 425972(PDK1)
PCOC: 116232736(PDK3) 116232853(PDK1) 116233565(PDK2) 116243255(PDK4)
MGP: 100540747(PDK4) 100551417(PDK1) 104915378
CJO: 107309122(PDK4) 107316706(PDK1) 107325193(PDK3) 107325226(PDK2)
NMEL: 110394291(PDK4) 110400361(PDK1) 110404303(PDK3)
APLA: 101790921(PDK1) 101793451(PDK3) 101796141(PDK4) 113840021(PDK2)
ACYG: 106029999(PDK1) 106037540(PDK4) 106037792(PDK3)
TGU: 100218846(PDK1) 100226102(PDK3) 100230570(PDK4) 116806667(PDK2)
LSR: 110474730(PDK4) 110474799(PDK2) 110482900(PDK1) 110483254(PDK3)
SCAN: 103812830(PDK4) 103814437(PDK1) 103815861(PDK3) 103825236 108964603
PMOA: 120498173(PDK2) 120503424(PDK4) 120504686(PDK3) 120513475(PDK1)
GFR: 102032982(PDK1) 102035869(PDK3) 102036508(PDK2) 102043114(PDK4)
FAB: 101810404(PDK4) 101812266(PDK2) 101812709(PDK1) 101819650(PDK3)
PHI: 102100647(PDK3) 102101703(PDK1) 102105276(PDK2) 102107706(PDK4)
PMAJ: 107198663(PDK2) 107200488(PDK4) 107204004(PDK3) 107207402(PDK1)
CCAE: 111922906(PDK3) 111924238(PDK4) 111932081(PDK1) 111940029
CCW: 104686204(PDK3) 104689332(PDK4) 104693871(PDK1) 120411189(PDK2)
ETL: 114054918(PDK1) 114057650(PDK3) 114069034(PDK2) 114072967(PDK4)
FPG: 101913912(PDK4) 101915736(PDK2) 101921375(PDK3) 101925003(PDK1)
FCH: 102050815(PDK1) 102050926(PDK3) 102054883(PDK4) 102055203(PDK2)
CLV: 102092387(PDK2) 102093738(PDK3) 102097281(PDK4) 102098636(PDK1)
EGZ: 104123442(PDK3) 104128057(PDK1) 104129066(PDK4)
NNI: 104010002(PDK1) 104012302(PDK2) 104012823(PDK4) 104022502(PDK3)
ACUN: 113477053(PDK4) 113479913(PDK3) 113482065(PDK1)
PADL: 103914484(PDK3) 103922372(PDK4) 103924235(PDK1)
AAM: 106483564(PDK4) 106492245(PDK3) 106492763(PDK2) 106499285(PDK1)
ASN: 102370160(PDK4) 102375213(PDK2) 102384931(PDK1) 102385909(PDK3)
AMJ: 102560712(PDK2) 102565725(PDK1) 102576429(PDK3) 106736620(PDK4)
CPOO: 109305961(PDK3) 109309012(PDK4) 109318943(PDK2) 109322659(PDK1)
GGN: 109291427(PDK4) 109301692(PDK1) 109302813(PDK3)
PSS: 102454133(PDK2) 102458098(PDK4) 102458322(PDK3) 102462980(PDK1)
CMY: 102930569(PDK4) 102931646(PDK3) 102934483(PDK2) 102942305(PDK1)
CPIC: 101939116(PDK4) 101939432(PDK1) 101947440(PDK3) 101948702(PDK2)
TST: 117868772(PDK3) 117869198(PDK2) 117872231(PDK4) 117884723(PDK1)
CABI: 116820150(PDK3) 116829232(PDK4) 116831478(PDK2) 116831976
ACS: 100555492(pdk1) 100560978(pdk4) 100562544(pdk3) 100565122(pdk2)
PVT: 110074717(PDK4) 110076723(PDK3) 110079134(PDK2) 110086017(PDK1)
PBI: 103048669(PDK2) 103052031(PDK4) 103052758(PDK1) 103063932(PDK3)
PMUR: 107282609(PDK2) 107283650(PDK4) 107291526(PDK1) 107298473(PDK3)
TSR: 106542459 106543989(PDK4) 106545023(PDK3) 106545193(PDK2)
PGUT: 117654883(PDK4) 117664511(PDK2) 117671546(PDK1) 117674927(PDK3)
PMUA: 114581688(PDK2) 114596206(PDK3) 114606930(PDK1) 114607069(PDK4)
ZVI: 118085064(PDK3) 118092009(PDK4) 118094214(PDK2) 118094675(PDK1)
GJA: 107107054(PDK1) 107112128 107112529(PDK2) 107114025(PDK3) 107118002(PDK4)
XLA: 108707984(pdk3.L) 108709313(pdk3.S) 379789(pdk4.L) 398840(pdk4.S) 432080(pdk1.L) 494745(pdk1.S)
XTR: 100135009(pdk3) 100497838(pdk1) 448511(pdk4)
NPR: 108790502(PDK4) 108790791(PDK3) 108800388(PDK1)
DRE: 393971(pdk2b) 555840(pdk1) 560068(pdk3a) 561007(pdk4) 794083(pdk2a)
SRX: 107705263 107718451 107721408 107721912 107722149 107731629 107742969 107743772 107748117 107752527 107753849 107754097
SANH: 107656160 107657352(pdk1) 107663620 107665156 107666345 107669734 107671276 107677886 107685479 107689197
SGH: 107549851 107562510 107565668 107568951 107586717 107588235 107588762 107590079 107590342 107591595 107593573(pdk4)
CCAR: 109066468 109073837 109090406 109091412 109103050 109112616
CAUA: 113038391 113042479 113053526 113062056 113062409 113062650 113066199 113111491 113119362 113119818 113119880
IPU: 108256566(pdk3) 108257133(pdk4) 108266331(pdk1) 108274275 108278474
PHYP: 113526171(pdk1) 113527631 113536342(pdk4) 113541070 113541694
AMEX: 103027445(pdk4) 103028931 103033744(pdk1) 103035067 103043532 103046317
EEE: 113574398 113578677 113582550 113585704 113588394(pdk1) 113589636
TRU: 101066123(pdk3) 101066998(pdk1) 101070423 101071739(pdk4) 101074391
TNG: GSTEN00006869G001 GSTEN00015521G001 GSTEN00031435G001 GSTEN00031477G001
LCO: 104921112(pdk3) 104922841(pdk4) 104925155 104927162 104927781(pdk1)
NCC: 104940782(pdk3) 104948256(pdk1) 104964252 104965721
ELY: 117247416(pdk2a) 117251613(pdk1) 117263920(pdk4) 117264726(pdk3a) 117268879
PLEP: 121948831(pdk1) 121956983 121957619(pdk4) 121960420(pdk3a) 121964955
SLUC: 116037946(pdk3a) 116048487(pdk1) 116061258(pdk2a) 116062847 116066907(pdk4)
GAT: 120811572(pdk3a) 120819247(pdk2a) 120826161(pdk4) 120828007 120834406(pdk1)
MSAM: 119884287 119887935 119904103(pdk1) 119907792 119908916(pdk3a) 119915847(pdk2a)
CUD: 121503371 121522539(pdk1) 121523956(pdk4) 121527199(pdk3a) 121528431(pdk2a)
MZE: 101472257 101479514(pdk3) 101482626(pdk1) 101483754(pdk4)
ONL: 100690776(pdk4) 100700648(pdk1) 100701650 100706734(pdk3)
OAU: 116319466(pdk4) 116323010(pdk1) 116328267(pdk3a) 116335611(pdk2a)
OLA: 101155612(pdk4) 101161766(pdk1) 101171116(pdk3) 101175202
OML: 112151208(pdk3a) 112154423(pdk2a) 112154859(pdk1) 112162963(pdk4)
XMA: 102220162(pdk4) 102223173 102228650(pdk3) 102235390(pdk1)
XCO: 114136739(pdk3) 114148095(pdk1) 114152118 114156304(pdk4)
XHE: 116711645(pdk3) 116723063(pdk1) 116727262 116731498(pdk4)
PRET: 103458449(pdk1) 103460042 103481842 103482447(pdk3)
CVG: 107085884(pdk4) 107093223 107096086 107102278(pdk1)
NFU: 107382959(pdk3) 107383300(pdk4) 107387611 107390016(pdk1)
KMR: 108239328(pdk4) 108240758(pdk1) 108243174(pdk3a) 108249334(pdk2a)
ALIM: 106512868(pdk1) 106521954 106524805(pdk3) 106534797
AOCE: 111580959 111582187(pdk1) 111583715 111587703(pdk3)
CSEM: 103376980(pdk3) 103381868 103391842(pdk1) 103393542 103394119(pdk4)
POV: 109624577 109629754(pdk3) 109631285(pdk1) 109631860(pdk4) 109639927
LCF: 108877204(pdk4) 108888700(pdk1) 108892051 108902052(pdk3)
SDU: 111218429(pdk1) 111219703 111223416(pdk4) 111237227(pdk3)
SLAL: 111655415 111656919(pdk4) 111662973 111668530(pdk1)
XGL: 120785908(pdk4) 120786116 120790240(pdk3a) 120794330(pdk2a) 120801399(pdk1)
HCQ: 109507862(pdk1) 109508605 109511882 109515220 109530168
BPEC: 110154243 110158166 110160957(pdk3) 110166617(pdk1) 110168202
MALB: 109958057(pdk1) 109962761 109964796 109965553(pdk3) 109968179(pdk4)
SASA: 100194609(pdk3) 106570467 106578452(PDK3) 106579320 106586231(pdk1) 106588934 106600850 106607477(PDK2)
OTW: 112223568 112225914 112228891 112229481 112234909(pdk3) 112236653 112258536 112264354
OMY: 110486156 110488016 110491496(pdk2a) 110496630(pdk4) 110520110(pdk1) 110534066 110535441 110538080
SALP: 111950597 111963718 111972933 111975134 111978175 111981212 111981769 112068414 112068425
ELS: 105007365 105013241 105016204(pdk1) 105019627(pdk3) 105022782(pdk4) 105027696
SFM: 108918813 108920673(pdk1) 108922009(pdk4) 108923750 108939688
PKI: 111835791(pdk3) 111840669 111843911(pdk4) 111845173 111852280
LOC: 102689070(pdk1) 102689628 102689939(pdk4) 102694075(pdk3)
PSPA: 121301856 121302839(pdk3a) 121315036(pdk4) 121321396(pdk1) 121324237
ARUT: 117394947(pdk4) 117399513 117405913 117407271 117426313 117433481 117435044 117971176
LCM: 102347516(PDK2) 102354798(PDK3)
CMK: 103176918(pdk4) 103183848(pdk2) 103184837(pdk3)
RTP: 109914991 109934162(pdk3) 109935855
BFO: 118403139
CIN: 100185085
SCLV: 120342311
APLC: 110977370
SKO: 100375387
DME: Dmel_CG8808(Pdk)
DER: 6541111
DSE: 6608352
DSI: Dsimw501_GD10655(Dsim_GD10655)
DYA: Dyak_GE19277
DAN: 6495314
DSR: 110177125
DPO: Dpse_GA30459
DPE: 6592195
DMN: 108158730 117193401
DWI: 6640984
DGR: Dgri_GH19919
DMO: Dmoj_GI19876
DAZ: 108615926
DNV: 108653823
DHE: 111604602
DVI: 6636500
MDE: 101896544
LCQ: 111688894
AGA: AgaP_AGAP010276
ACOZ: 120960033
AARA: 120904951
AAG: 5569118
AALB: 109414459 109621250 115266328
CQU: CpipJ_CPIJ013528
AME: 410424
ACER: 107998838
BIM: 100740637
BTER: 100651342
CCAL: 108633033
OBB: 114880709
MGEN: 117218847
NMEA: 116426865
SOC: 105196176
MPHA: 105840769
AEC: 105145793
ACEP: 105624222
PBAR: 105430164
VEM: 105567175
HST: 105184354
DQU: 106751135
CFO: 105254566
FEX: 115236023
LHU: 105667675
PGC: 109857987
OBO: 105278201
PCF: 106792239
NVI: 100122108
CSOL: 105361037
MDL: 103576368
TCA: 662090
DPA: 109543594
ATD: 109605857
AGB: 108904718
NVL: 108566338
APLN: 108741385
PPYR: 116176946
OTU: 111418780
BMOR: 100136898(Pdk)
BMAN: 114251157
MSEX: 115439768
DPL: KGM_210186A KGM_210186B
BANY: 112054343
PMAC: 106715299
PPOT: 106101913
PXU: 106124323
PRAP: 110999946
ZCE: 119836410
HAW: 110379901
TNL: 113507471
PXY: 105398591
API: 100166307
DNX: 107164354
AGS: 114131694
RMD: 113555897
BTAB: 109033857
DCI: 103515710
CLEC: 106661526
NLU: 111046083
PHU: Phum_PHUM574180
ZNE: 110830100
CSEC: 111874174
FCD: 110862532
DPX: DAPPUDRAFT_240818
PVM: 113820493
HAME: 121875703
EAF: 111696072 111703879 111707074 111711512
DSV: 119456303
RSAN: 119393567 119402211
RMP: 119171878
VDE: 111253310
VJA: 111270221
TUT: 107364003
DPTE: 113797125
CSCU: 111618672
PTEP: 107446614
SDM: 118196190
CEL: CELE_ZK370.5(pdhk-2)
CBR: CBG06929(Cbr-pdhk-2)
BMY: BM_BM13766(Bma-pdhk-2)
LOA: LOAG_02700
NAI: NECAME_00928
TSP: Tsp_01201 Tsp_01211
HRO: HELRODRAFT_111666 HELRODRAFT_115050
LGI: LOTGIDRAFT_111147
PCAN: 112556504
BGT: 106059039
GAE: 121385433
CRG: 105337605
PMAX: 117314684
OBI: 106874800
LAK: 106151501
SMM: Smp_068170.1 Smp_140580
SHX: MS3_0016527 MS3_0019933
OVI: T265_00108 T265_02970
EGL: EGR_07392
NVE: 5514023
EPA: 110245620
ATEN: 116307513
ADF: 107338823
AMIL: 114965217
PDAM: 113686862
SPIS: 111319016 111341445 111341446
DGT: 114519114
HMG: 100211141
TAD: TRIADDRAFT_20860 TRIADDRAFT_53587
ATH: AT3G06483(PDK)
ALY: 9320654
CRB: 17891628
CSAT: 104724169 104744817 104764342
EUS: EUTSA_v10020969mg
BRP: 103859160 103870744
BNA: 106397540 106431763 106439090 106453000
BOE: 106292637 106328083
RSZ: 108856223 108861192
THJ: 104798546 104802717 104818862 104827107
CPAP: 110808360
CIT: 102615178
CIC: CICLE_v10005215mg
PVY: 116144486
TCC: 18603766
GRA: 105775486 105776969
GHI: 107916251 107942338 121203709 121213731
GAB: 108483820 108489452
DZI: 111306984
EGR: 104415295
GMX: 100037469(PDK3) 100779408 100785344 100814079
GSJ: 114367928 114381335 114388187 114392134
PVU: PHAVU_009G219900g PHAVU_009G2200001
VRA: 106766729 106778344
VAR: 108319438 108337382
VUN: 114164544 114177182
CCAJ: 109804349 109808743
APRC: 113874310
MTR: MTR_2g045490 MTR_7g024460
CAM: 101496392(Pdk) 101500787
LJA: Lj0g3v0267349.1(Lj0g3v0267349.1) Lj4g3v2249050.1(Lj4g3v2249050.1) Lj6g3v1126390.1(Lj6g3v1126390.1)
ADU: 107458797 107479469
AIP: 107611267 107630569
AHF: 112704069 112738417 112773136 112790589
LANG: 109327095 109343612
FVE: 101310404
RCN: 112198319
PPER: 18792242
PMUM: 103323292
PAVI: 110763836
PDUL: 117634649
MDM: 103452620 103452727
PXB: 103944686 103950319 103959091
ZJU: 107433361
MNT: 21407862
CSV: 101204312 101213546
CMO: 103483922 103490853
BHJ: 120072509 120082812
MCHA: 111009461
CMAX: 111479408
CMOS: 111457914
CPEP: 111791452
RCU: 8261345
JCU: 105643624
HBR: 110635268
MESC: 110611773
POP: 7496482
PEU: 105107180
PALZ: 118057332
JRE: 108979892 108981587
QSU: 111983780 111997771 112000920 112035225 112039992
QLO: 115994815
TWL: 120000101
VVI: 100245923 100266622
VRI: 117914444 117929784
SLY: 101249536 101253414
SPEN: 107006756 107007988
SOT: 102580217 102593359
CANN: 107840100 107851511
NTA: 107774290 107779147 107798697 107830420
NSY: 104231883 104246029
NTO: 104114413 104116301
NAU: 109232180 109235703
INI: 109175738
ITR: 116002151
SIND: 105156800
OEU: 111371553 111385763
EGT: 105960376
HAN: 110868249 110941261
LSV: 111880400
CCAV: 112527429
DCR: 108193395 108204370
CSIN: 114256634 114308383 114323407
BVG: 104889154
SOE: 110790972
CQI: 110717420 110722049
NNU: 104607140 104611263
MING: 122058206 122089821
PSOM: 113332752 113334808 113347025 113358009
NCOL: 116254246
OSA: 4332932 4344039
DOSA: Os03t0370000-01(Os03g0370000) Os07t0637300-01(Os07g0637300)
OBR: 102700877 102704822
BDI: 100822823 100842984
ATS: 109735306 109769724
TDC: 119290667 119353648 119362823
SBI: 8063534 8080774
ZMA: 100193944 103638995 541677(pdlk1) 542603(pdlk2)
SITA: 101756026 101786452
PVIR: 120652246 120652247 120661963 120691591 120694631
PHAI: 112876231 112880139
PDA: 103707688 103720053 120112039
EGU: 105061503
MUS: 103970414 103971998 103993306
DCT: 110099184
PEQ: 110037896
AOF: 109842738 109848819
ATR: 18430097
SMO: SELMODRAFT_108744 SELMODRAFT_164498 SELMODRAFT_268711 SELMODRAFT_93519
PPP: 112286524 112292562
CRE: CHLRE_05g241750v5 CHLRE_06g278451v5
VCN: VOLCADRAFT_54923 VOLCADRAFT_66749
MNG: MNEG_10111 MNEG_1132
CSL: COCSUDRAFT_36801
CVR: CHLNCDRAFT_137427
APRO: F751_4520
OLU: OSTLU_46874
OTA: OT_ostta10g02700
BPG: Bathy11g02780
MIS: MICPUN_108584
MPP: MICPUCDRAFT_50396
CME: CYME_CMR225C
GSL: Gasu_13110
CCP: CHC_T00008298001
SCE: YGL059W(PKP2) YIL042C(PKP1)
AGO: AGOS_AAR157C AGOS_ADL116C AGOS_AER270W
ERC: Ecym_2505 Ecym_3076 Ecym_4378
KLA: KLLA0_C05654g KLLA0_E04533g KLLA0_F27423g
KMX: KLMA_10248(PKP2) KLMA_20512(PKP1) KLMA_40335
LTH: KLTH0A03916g KLTH0H06710g
VPO: Kpol_461p7 Kpol_478p21
ZRO: ZYRO0C04928g ZYRO0D08052g ZYRO0D16544g
CGR: CAGL0F07007g CAGL0L00869g
NCS: NCAS_0A13390(NCAS0A13390) NCAS_0D03210(NCAS0D03210)
NDI: NDAI_0A02650(NDAI0A02650) NDAI_0I01660(NDAI0I01660)
TPF: TPHA_0B02740(TPHA0B02740) TPHA_0J01760(TPHA0J01760)
TBL: TBLA_0B01550(TBLA0B01550) TBLA_0F02450(TBLA0F02450)
TDL: TDEL_0G03600(TDEL0G03600) TDEL_0H02230(TDEL0H02230)
TGB: HG536_0C04710 HG536_0H03720
KAF: KAFR_0A04690(KAFR0A04690) KAFR_0I01930(KAFR0I01930)
ZMK: HG535_0A07510 HG535_0F03550 HG535_0G02070
PPA: PAS_chr1-1_0202 PAS_chr1-1_0297 PAS_chr3_0360 PAS_chr4_0756
DHA: DEHA2B02486g DEHA2C13354g DEHA2C13970g
PIC: PICST_28836 PICST_29203(BCK4) PICST_90317
PGU: PGUG_00052 PGUG_00855 PGUG_05616
SPAA: SPAPADRAFT_59187 SPAPADRAFT_59977 SPAPADRAFT_61645
LEL: LELG_00523 LELG_03474 LELG_05335
CAL: CAALFM_CR08860WA(PDK2)
CTP: CTRG_01003 CTRG_03664 CTRG_05965
COT: CORT_0A04130 CORT_0D01220 CORT_0D03530
CDU: CD36_34370
CTEN: CANTEDRAFT_115456 CANTEDRAFT_132437 CANTEDRAFT_94107
YLI: YALI0C21582g YALI0F26807g
CLU: CLUG_00082 CLUG_01102 CLUG_04359
CLUS: A9F13_04g01507 A9F13_09g01595 A9F13_19g00143
CAUR: CJI97_000690 CJI97_000865 CJI97_004808
SLB: AWJ20_2336(PKP2) AWJ20_864(PKP1)
PKZ: C5L36_0A03230 C5L36_0B08090 C5L36_0C04500 C5L36_0D02925
BNN: FOA43_001136 FOA43_002429 FOA43_004313
BBRX: BRETT_000256 BRETT_002112 BRETT_003542
NCR: NCU03796(stk-24) NCU06760(stk-48)
NTE: NEUTE1DRAFT111129(NEUTE1DRAFT_111129) NEUTE1DRAFT58210(NEUTE1DRAFT_58210)
SMP: SMAC_02642 SMAC_06751
PAN: PODANSg6632 PODANSg9041
TTT: THITE_2108382 THITE_2124496
MTM: MYCTH_2302183 MYCTH_84590
CTHR: CTHT_0013820 CTHT_0061220
MGR: MGG_07161 MGG_07467
TMN: UCRPA7_891
SSCK: SPSK_01643 SPSK_02551
FGR: FGSG_04416 FGSG_07381
FPU: FPSE_04197 FPSE_06338
FVR: FVEG_07895 FVEG_11246
FOX: FOXG_01533 FOXG_13817
NHE: NECHADRAFT_49344 NECHADRAFT_95779
TRE: TRIREDRAFT_50068 TRIREDRAFT_81855
TRR: M419DRAFT_101867 M419DRAFT_104011
MAW: MAC_00471 MAC_01792
MAJ: MAA_05401 MAA_07333
CMT: CCM_01061 CCM_09141
PLJ: VFPFJ_03816 VFPFJ_07799
VAL: VDBG_05287
VDA: VDAG_01475 VDAG_06937
CFJ: CFIO01_10103 CFIO01_10163
SAPO: SAPIO_CDS1047 SAPIO_CDS9576
ELA: UCREL1_11271 UCREL1_473
PFY: PFICI_08313 PFICI_11255
SSL: SS1G_10371
BFU: BCIN_14g03890 BCIN_15g02600(Bcpkp2)
MBE: MBM_04625
PSCO: LY89DRAFT_44651 LY89DRAFT_644812
GLZ: GLAREA_03189 GLAREA_06473
ANI: AN6207.2 AN9461.2
AFM: AFUA_2G11900 AFUA_5G03240
ACT: ACLA_001930 ACLA_070830
NFI: NFIA_038890 NFIA_087120
AOR: AO090026000452 AO090102000525
ANG: ANI_1_544024(An02g04000) ANI_1_682084(An09g05460)
AFV: AFLA_005829 AFLA_011953
PCS: Pc20g14220 Pc21g16190
PDP: PDIP_31940 PDIP_49130
TMF: PMAA_082400 PMAA_091840
TRG: TRUGW13939_06952 TRUGW13939_08405
CIM: CIMG_05416 CIMG_06539
CPW: CPC735_030110 CPC735_065780
PBL: PAAG_00094 PAAG_04321
PBN: PADG_07553 PADG_12250(PADG_07168)
URE: UREG_03898 UREG_06303
ABE: ARB_00632 ARB_06862
TVE: TRV_05098 TRV_05975
AJE: HCAG_00519 HCAG_03915
BGH: BDBG_01389 BDBG_05688
PNO: SNOG_10913 SNOG_15668(SNOG_15666 SNOG_15667)
PTE: PTT_00963 PTT_18105
BZE: COCCADRAFT_107293 COCCADRAFT_21753
BSC: COCSADRAFT_78141 COCSADRAFT_82103
BOR: COCMIDRAFT_28292 COCMIDRAFT_29220
AALT: CC77DRAFT_304888 CC77DRAFT_931602
ZTR: MYCGRDRAFT_110505 MYCGRDRAFT_53419
PFJ: MYCFIDRAFT_32163 MYCFIDRAFT_48088
BCOM: BAUCODRAFT_123897 BAUCODRAFT_222410
NPA: UCRNP2_6290 UCRNP2_886
TML: GSTUM_00002314001 GSTUM_00003362001
SPO: SPAC644.11c(pkp1)
CNE: CNA00360 CNI04400
CNB: CNBA0360 CNBH4200
CGI: CGB_B0390C CGB_H5750W
TMS: TREMEDRAFT_27661
TASA: A1Q1_01815
TVS: TRAVEDRAFT_31114 TRAVEDRAFT_44775
DSQ: DICSQDRAFT_157150 DICSQDRAFT_180862
PCO: PHACADRAFT_116406 PHACADRAFT_250081
SHS: STEHIDRAFT_104614 STEHIDRAFT_93627
HIR: HETIRDRAFT_45872 HETIRDRAFT_460407
PSQ: PUNSTDRAFT_135059 PUNSTDRAFT_51259
ADL: AURDEDRAFT_110505 AURDEDRAFT_115237 AURDEDRAFT_117493
FME: FOMMEDRAFT_110897 FOMMEDRAFT_20550
GTR: GLOTRDRAFT_112124 GLOTRDRAFT_70547
LBC: LACBIDRAFT_190061 LACBIDRAFT_311816
MPR: MPER_04518 MPER_11803
MRR: Moror_12432 Moror_6956 Moror_7374 Moror_9054
CCI: CC1G_00337 CC1G_15212
SCM: SCHCODRAFT_62949 SCHCODRAFT_70039
ABP: AGABI1DRAFT123518(AGABI1DRAFT_123518) AGABI1DRAFT72910(AGABI1DRAFT_72910)
ABV: AGABI2DRAFT179568(AGABI2DRAFT_179568) AGABI2DRAFT203285(AGABI2DRAFT_203285)
CPUT: CONPUDRAFT_110835 CONPUDRAFT_145842
SLA: SERLADRAFT_382679 SERLADRAFT_457378
WSE: WALSEDRAFT_61107
WIC: J056_003549
UMA: UMAG_05275
PFP: PFL1_05374
MGL: MGL_0242 MGL_2833
MRT: MRET_1073 MRET_3429
MSYM: MSY001_3065 MSY001_3371
PGR: PGTG_14708 PGTG_17358
MLR: MELLADRAFT_41804 MELLADRAFT_78543
MBR: MONBRDRAFT_31036
SRE: PTSG_00845
ACAN: ACA1_019150
SMIN: v1.2.006537.t1(symbB.v1.2.006537.t1) v1.2.009791.t1(symbB.v1.2.009791.t1) v1.2.017212.t1(symbB.v1.2.017212.t1) v1.2.019767.t1(symbB.v1.2.019767.t1) v1.2.020323.t1(symbB.v1.2.020323.t1) v1.2.020323.t2(symbB.v1.2.020323.t2) v1.2.027845.t1(symbB.v1.2.027845.t1) v1.2.027845.t2(symbB.v1.2.027845.t2) v1.2.033580.t1(symbB.v1.2.033580.t1) v1.2.033580.t2(symbB.v1.2.033580.t2) v1.2.036480.t1(symbB.v1.2.036480.t1) v1.2.036764.t1(symbB.v1.2.036764.t1) v1.2.039627.t1(symbB.v1.2.039627.t1)
PTI: PHATRDRAFT_13123 PHATRDRAFT_15081 PHATRDRAFT_46264 PHATRDRAFT_50961
FCY: FRACYDRAFT_189611 FRACYDRAFT_226529
TPS: THAPSDRAFT_1225 THAPSDRAFT_261233(PDK1_1) THAPSDRAFT_37571
NGD: NGA_0219900 NGA_2010000
AAF: AURANDRAFT_35155
PIF: PITG_00352 PITG_01458 PITG_01461 PITG_02642
PSOJ: PHYSODRAFT_294940 PHYSODRAFT_300151 PHYSODRAFT_314481 PHYSODRAFT_316081 PHYSODRAFT_501168
SPAR: SPRG_01441 SPRG_10674
EHX: EMIHUDRAFT_448217(PDK2) EMIHUDRAFT_461826(PDK4) EMIHUDRAFT_72492(PDK1) EMIHUDRAFT_89159(PDK3)
GTT: GUITHDRAFT_104150 GUITHDRAFT_63012 GUITHDRAFT_63563 GUITHDRAFT_67612
TBR: TB927.1.1000 Tb11.02.2390
TBG: TbgDal_I380 TbgDal_XI5400
TCR: 509875.170 511421.110
LMA: LMJF_20_0280 LMJF_24_0010
LIF: LINJ_20_0310 LINJ_24_0010
LDO: LDBPK_200310 LDBPK_240010
LMI: LMXM_20_0280 LMXM_24_0010
LBZ: LBRM_20_4500 LBRM_24_0010
LPAN: LPMP_204510 LPMP_240010
NGR: NAEGRDRAFT_74828 NAEGRDRAFT_82050
 » show all
Reference
1  [PMID:4401694]
  Authors
Linn TC, Pelley JW, Pettit FH, Hucho F, Randall DD, Reed LJ.
  Title
-Keto acid dehydrogenase complexes. XV. Purification and properties of the component enzymes of the pyruvate dehydrogenase complexes from bovine kidney and heart.
  Journal
Arch Biochem Biophys 148:327-42 (1972)
DOI:10.1016/0003-9861(72)90151-8
Reference
2  [PMID:3004826]
  Authors
Reed LJ, Damuni Z, Merryfield ML.
  Title
Regulation of mammalian pyruvate and branched-chain alpha-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation.
  Journal
Curr Top Cell Regul 27:41-9 (1985)
DOI:10.1016/b978-0-12-152827-0.50011-6
Reference
3  [PMID:15629119]
  Authors
Tovar-Mendez A, Hirani TA, Miernyk JA, Randall DD.
  Title
Analysis of the catalytic mechanism of pyruvate dehydrogenase kinase.
  Journal
Arch Biochem Biophys 434:159-68 (2005)
DOI:10.1016/j.abb.2004.10.017
  Sequence
[ath:AT3G06483]
Reference
4  [PMID:15491151]
  Authors
Bao H, Kasten SA, Yan X, Hiromasa Y, Roche TE.
  Title
Pyruvate dehydrogenase kinase isoform 2 activity stimulated by speeding up the rate of dissociation of ADP.
  Journal
Biochemistry 43:13442-51 (2004)
DOI:10.1021/bi0494875
Reference
5  [PMID:12631265]
  Authors
Roche TE, Hiromasa Y, Turkan A, Gong X, Peng T, Yan X, Kasten SA, Bao H, Dong J.
  Title
Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1.
  Journal
Eur J Biochem 270:1050-6 (2003)
DOI:10.1046/j.1432-1033.2003.03468.x
Other DBs
ExplorEnz - The Enzyme Database: 2.7.11.2
IUBMB Enzyme Nomenclature: 2.7.11.2
ExPASy - ENZYME nomenclature database: 2.7.11.2
BRENDA, the Enzyme Database: 2.7.11.2
CAS: 9074-01-5

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