KEGG   ENZYME: 2.7.11.2Help
Entry
EC 2.7.11.2                 Enzyme                                 

Name
[pyruvate dehydrogenase (acetyl-transferring)] kinase;
PDH kinase;
PDHK;
PDK;
PDK1;
PDK2;
PDK3;
PDK4;
pyruvate dehydrogenase kinase;
pyruvate dehydrogenase kinase (phosphorylating);
pyruvate dehydrogenase kinase activator protein;
STK1
Class
Transferases;
Transferring phosphorus-containing groups;
Protein-serine/threonine kinases
BRITE hierarchy
Sysname
ATP:[pyruvate dehydrogenase (acetyl-transferring)] phosphotransferase
Reaction(IUBMB)
ATP + [pyruvate dehydrogenase (acetyl-transferring)] = ADP + [pyruvate dehydrogenase (acetyl-transferring)] phosphate [RN:R03449]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
[pyruvate dehydrogenase (acetyl-transferring)] [CPD:C01256]
Product
ADP [CPD:C00008];
[pyruvate dehydrogenase (acetyl-transferring)] phosphate [CPD:C01293]
Comment
The enzyme has no activating compound but is specific for its substrate. It is a mitochondrial enzyme associated with the pyruvate dehydrogenase complex in mammals. Phosphorylation inactivates EC 1.2.4.1, pyruvate dehydrogenase (acetyl-transferring).
History
EC 2.7.11.2 created 1978 as EC 2.7.1.99, transferred 2005 to EC 2.7.11.2
Orthology
K00898  pyruvate dehydrogenase kinase 2/3/4
K12077  pyruvate dehydrogenase kinase isoform 1
Genes
HSA: 5163(PDK1) 5164(PDK2) 5165(PDK3) 5166(PDK4)
PTR: 459743(PDK1) 468402(PDK2) 472448(PDK4) 740576(PDK3)
PPS: 100968174(PDK1) 100970620(PDK4) 100992308(PDK2) 100995647(PDK3)
GGO: 101129032(PDK2) 101143387(PDK3) 101149286(PDK4) 101150048(PDK1)
PON: 100174113(PDK2) 100435148(PDK4) 100442853(PDK1) 100462571(PDK3)
NLE: 100597085(PDK2) 100598085(PDK3) 100601990(PDK1) 100605243(PDK4)
MCC: 697772(PDK1) 698726(PDK4) 699394(PDK3) 704169(PDK2)
MCF: 101867293(PDK2) 102118837(PDK3) 102119067(PDK4) 102132161(PDK1)
CSAB: 103217325(PDK1) 103226523(PDK4) 103231727(PDK3) 103242950(PDK2)
RRO: 104654150(PDK3) 104656590(PDK4) 104673517(PDK1) 104680263(PDK2)
RBB: 108513535(PDK4) 108516442(PDK2) 108522274(PDK1) 108524111(PDK3)
CJC: 100386396(PDK2) 100388325(PDK3) 100402844(PDK1) 100407216(PDK4)
SBQ: 101037963(PDK1) 101038610(PDK3) 101048009(PDK2) 101049325(PDK4)
MMU: 18604(Pdk2) 228026(Pdk1) 236900(Pdk3) 27273(Pdk4)
RNO: 116551(Pdk1) 296849(Pdk3) 81530(Pdk2) 89813(Pdk4)
CGE: 100758762(Pdk2) 100763413(Pdk4) 100770270(Pdk3) 100774056(Pdk1)
NGI: 103725230(Pdk4) 103725376(Pdk3) 103728651 103738377(Pdk2) 103751806(Pdk1)
HGL: 101698433(Pdk4) 101699582(Pdk3) 101699994(Pdk2) 101705587(Pdk1)
CCAN: 109691403(Pdk2) 109697144(Pdk3) 109699522(Pdk1) 109701002(Pdk4)
OCU: 100348343(PDK2) 100351323(PDK1) 100351580(PDK4) 100352037(PDK3)
TUP: 102468786(PDK4) 102469133(PDK2) 102483149(PDK3) 102499515(PDK1)
CFA: 476828(PDK1) 480868(PDK3) 482310(PDK4) 491075(PDK2)
AML: 100464908(PDK4) 100466029(PDK3) 100476739(PDK2) 100483652(PDK1)
UMR: 103658746(PDK4) 103659566(PDK1) 103660465(PDK2) 103668186(PDK3)
ORO: 101362728(PDK3) 101367021(PDK2) 101370661(PDK4) 101383119(PDK1)
FCA: 101092256(PDK4) 101092705(PDK1) 101095314(PDK3) 101100013(PDK2)
PTG: 102948846(PDK3) 102951784 102960301(PDK1) 102963206(PDK2) 102969030(PDK4)
AJU: 106970005(PDK4) 106985184(PDK2) 106986815(PDK3) 106987925(PDK1)
BTA: 507367(PDK4) 510841(PDK3) 524075(PDK2) 528655(PDK1)
BOM: 102264999(PDK4) 102265648(PDK1) 102266253(PDK2) 102275065(PDK3)
BIU: 109555405(PDK3) 109558225(PDK4) 109566453(PDK1) 109573763(PDK2)
PHD: 102327657(PDK4) 102329508(PDK2) 102337867(PDK3) 102339076(PDK1)
CHX: 102180838(PDK3) 102185217(PDK2) 102186251(PDK1) 102190015(PDK4)
OAS: 101108725(PDK3) 101108929(PDK2) 101113205(PDK1) 101117752(PDK4)
SSC: 100153858(PDK3) 100286778(PDK4) 100286871(PDK1) 100516037(PDK2)
CFR: 102508070(PDK2) 102511071(PDK3) 102518730(PDK4) 102518782(PDK1)
CDK: 105088722(PDK4) 105091095(PDK1) 105103897(PDK3) 105104826(PDK2)
BACU: 103000815(PDK4) 103007993 103016999(PDK1) 103018751(PDK2)
LVE: 103072788(PDK2) 103073094(PDK4) 103073975(PDK3) 103078387(PDK1)
OOR: 101271748(PDK1) 101279937(PDK2) 101286339(PDK4) 101288876(PDK3)
ECB: 100052078(PDK4) 100060791(PDK3) 100064091(PDK1) 100147514(PDK2)
EPZ: 103542208 103543124 103551054(PDK2) 103553122(PDK1) 103555010(PDK4)
EAI: 106824116(PDK3) 106826450(PDK2) 106834715(PDK1) 106838924(PDK4)
MYB: 102251531(PDK4) 102255458(PDK3) 102259213(PDK2) 102262215(PDK1)
MYD: 102767099(PDK1) 102774306(PDK3) 102775297(PDK2) 102775518(PDK4)
HAI: 109372242(PDK3) 109380767(PDK2) 109390399(PDK1) 109393138(PDK4)
RSS: 109445225(PDK1) 109446399(PDK4) 109451978(PDK2) 109461091(PDK3)
PALE: 102880150(PDK4) 102883688(PDK1) 102885302(PDK2) 102888523(PDK3)
LAV: 100655808(PDK1) 100670251 100671485(PDK3) 100674220(PDK4)
TMU: 101341826 101355780 101357823 101360007
MDO: 100010271(PDK3) 100017644(PDK4) 100022514(PDK2) 100617164(PDK1)
SHR: 100924143(PDK2) 100924902(PDK3) 100932777(PDK1) 100934205(PDK4)
OAA: 100084173(PDK1) 100088087(PDK4)
GGA: 107050147(PDKI2) 418595(PDK3) 420570(PDK4) 425972(PDK1)
MGP: 100540747(PDK4) 100548787 100551417(PDK1)
CJO: 107309122(PDK4) 107316706(PDK1) 107325193(PDK3) 107325226(PDK2)
APLA: 101790921(PDK1) 101793451(PDK3) 101796141(PDK4) 113840021(PDK2)
ACYG: 106029999(PDK1) 106037540(PDK4) 106037792(PDK3)
TGU: 100218846(PDK1) 100226102(PDK3) 100230570(PDK4)
SCAN: 103812830(PDK4) 103814437(PDK1) 103815861(PDK3) 103825236
GFR: 102032982(PDK1) 102035869(PDK3) 102036508(PDK2) 102043114(PDK4)
FAB: 101810404(PDK4) 101812266(PDK2) 101812709(PDK1) 101819650(PDK3)
PHI: 102100647(PDK3) 102101703(PDK1) 102105276(PDK2) 102107706(PDK4)
PMAJ: 107198663(PDK2) 107200488(PDK4) 107204004(PDK3) 107207402(PDK1)
CCAE: 111922906(PDK3) 111924238(PDK4) 111932081(PDK1) 111940029
CCW: 104686204(PDK3) 104689332(PDK4) 104693871(PDK1)
FPG: 101913912(PDK4) 101915736(PDK2) 101921375(PDK3) 101925003(PDK1)
FCH: 102050815(PDK1) 102050926(PDK3) 102054883(PDK4) 102055203(PDK2)
CLV: 102092387(PDK2) 102093738(PDK3) 102097281(PDK4) 102098636(PDK1)
EGZ: 104123442(PDK3) 104128057(PDK1) 104129066(PDK4) 104131408
NNI: 104010002(PDK1) 104012302(PDK2) 104012823(PDK4) 104022502(PDK3)
ACUN: 113477053(PDK4) 113479913(PDK3) 113482065(PDK1)
AAM: 106483564(PDK4) 106492245(PDK3) 106492763(PDK2) 106499285(PDK1)
ASN: 102370160(PDK4) 102375213(PDK2) 102384931(PDK1) 102385909(PDK3)
AMJ: 102560712(PDK2) 102565725(PDK1) 102576429(PDK3) 106736620(PDK4)
PSS: 102454133(PDK2) 102458098(PDK4) 102458322(PDK3) 102462980(PDK1)
CMY: 102930569(PDK4) 102931646(PDK3) 102934483(PDK2) 102942305(PDK1)
CPIC: 101939116(PDK4) 101939432(PDK1) 101947440(PDK3) 101948702(PDK2)
ACS: 100555492(pdk1) 100560978(pdk4) 100562544(pdk3) 100565122(pdk2)
PVT: 110074717(PDK4) 110076723(PDK3) 110079134(PDK2) 110086017(PDK1)
PBI: 103048669(PDK2) 103052031(PDK4) 103052758(PDK1) 103063932(PDK3)
PMUR: 107282609(PDK2) 107283650(PDK4) 107291526(PDK1) 107298473(PDK3)
GJA: 107107054(PDK1) 107112128 107112529(PDK2) 107114025(PDK3) 107118002(PDK4)
XLA: 108707984 108709313 379789(pdk4.L) 398840(pdk4.S) 432080(pdk1.L) 494745
XTR: 100135009(pdk3) 100497838(pdk1) 448511(pdk4)
NPR: 108790502(PDK4) 108790791(PDK3) 108800388(PDK1)
DRE: 393971(pdk2b) 555840(pdk1) 560068(pdk3a) 561007(pdk4) 794083(pdk2a)
SRX: 107705263 107718451 107721408 107721912 107722149 107731629 107742969 107743772 107748117 107752527 107753849 107754097
SANH: 107656160 107657352(pdk1) 107663620 107665156 107666345 107669734 107671276 107677886 107685479 107689197
SGH: 107549851 107562510 107565668 107568951 107586717 107588235 107588762 107590079 107590342 107591595 107593573(pdk4)
CCAR: 109066468 109073837 109090406 109091412 109103050 109112616
IPU: 108256566(pdk3) 108257133(pdk4) 108266331(pdk1) 108274275 108278474
PHYP: 113526171(pdk1) 113527631 113536342(pdk4) 113541070 113541694
AMEX: 103027445(pdk4) 103028931 103033744(pdk1) 103035067 103043532 103046317
EEE: 113574398 113578677 113582550 113585704 113588394(pdk1) 113589636
TRU: 101066123(pdk3) 101066998(pdk1) 101071739(pdk4) 101074391
TNG: GSTEN00001779G001 GSTEN00006869G001 GSTEN00015521G001 GSTEN00031435G001 GSTEN00031477G001
LCO: 104921112(pdk3) 104922841(pdk4) 104925155 104927162 104927781(pdk1)
NCC: 104940782(pdk3) 104948256(pdk1) 104964252 104965721
MZE: 101472257 101479514(pdk3) 101482626(pdk1) 101483754(pdk4)
OLA: 101155612(pdk4) 101161766(pdk1) 101171116(pdk3) 101175202
XMA: 102220162(pdk4) 102223173 102228650(pdk3) 102235390(pdk1)
PRET: 103458449(pdk1) 103460042 103481842 103482447(pdk3)
NFU: 107382959(pdk3) 107383300(pdk4) 107387611 107390016(pdk1)
KMR: 108239328(pdk4) 108240758 108243174(pdk3) 108249334
CSEM: 103376980(pdk3) 103381868 103391842(pdk1) 103393542 103394119(pdk4)
LCF: 108877204(pdk4) 108888700(pdk1) 108892051 108902052(pdk3)
SDU: 111218429(pdk1) 111219703 111223416(pdk4) 111237227(pdk3)
HCQ: 109507862(pdk1) 109508605 109511882 109515220 109530168
BPEC: 110154243 110158166 110160957(pdk3) 110166617(pdk1) 110168202
MALB: 109958057(pdk1) 109962761 109964796 109965553(pdk3) 109968179(pdk4)
SASA: 100194609(pdk3) 106570467 106578452(PDK3) 106579320 106586231(pdk1) 106588934 106600850 106607477(PDK2)
OTW: 112223568 112225914 112228891 112229481 112234909(pdk3) 112236653 112258536 112264354
SALP: 111950597 111963718 111972933 111975134 111978175 111981212 111981769 112068414 112068425
ELS: 105007365 105013241 105016204(pdk1) 105019627 105022782(pdk4) 105027696
SFM: 108918813 108920673(pdk1) 108922009(pdk4) 108923750 108939688
PKI: 111835791(pdk3) 111840669 111843911(pdk4) 111845173 111852280
LCM: 102347516(PDK2) 102354798(PDK3)
CMK: 103176918(pdk4) 103183848(pdk2) 103184837(pdk3)
BFO: BRAFLDRAFT_114859
CIN: 100185085
SPU: 587933
APLC: 110977370
SKO: 100375387
DME: Dmel_CG8808(Pdk)
DPO: Dpse_GA30459
DAN: Dana_GF12464
DER: 6541111
DPE: 6592195
DSE: Dsec_GM21122
DSI: Dsimw501_GD10655(Dsim_GD10655)
DWI: 6640984
DYA: Dyak_GE19277
DGR: Dgri_GH19919
DMO: Dmoj_GI19876
DVI: Dvir_GJ15047
MDE: 101896544
AGA: AgaP_AGAP010276
AAG: 5569118
CQU: CpipJ_CPIJ013528
AME: 410424
BIM: 100740637
BTER: 100651342
SOC: 105196176
MPHA: 105840769
AEC: 105145793
ACEP: 105624222
PBAR: 105430164
HST: 105184354
CFO: 105254566
LHU: 105667675
OBO: 105278201
PCF: 106792239
NVI: 100122108
MDL: 103576368
DPA: 109543594
DPL: KGM_210186A KGM_210186B
PMAC: 106715299
PRAP: 110999946
HAW: 110379901
TNL: 113507471
API: 100166307
DNX: 107164354
CLEC: 106661526
PHU: Phum_PHUM574180
ZNE: 110830100
FCD: 110862532
DPX: DAPPUDRAFT_240818
ISC: IscW_ISCW013649
TUT: 107364003
DPTE: 113797125
CEL: CELE_ZK370.5(pdhk-2)
CBR: CBG06929(Cbr-pdhk-2)
NAI: NECAME_00928
BMY: Bm1_30205
LOA: LOAG_02700
TSP: Tsp_01211
HRO: HELRODRAFT_111666 HELRODRAFT_115050 HELRODRAFT_69342
LGI: LOTGIDRAFT_111147
CRG: 105337605
OBI: 106874800
LAK: 106151501 106165756
SMM: Smp_068170.1 Smp_140580
SHX: MS3_10515 MS3_11112
OVI: T265_00108 T265_02970 T265_15976
EGL: EGR_07392
NVE: NEMVE_v1g232588
ADF: 107338823
PDAM: 113686862
SPIS: 111319016 111341445 111341446
HMG: 100211141
TAD: TRIADDRAFT_20860 TRIADDRAFT_53587
ATH: AT3G06483(PDK)
ALY: ARALYDRAFT_896779
CRB: 17891628
CSAT: 104724169 104744817 104764342
EUS: EUTSA_v10020969mg
BRP: 103859160 103870744
BNA: 106397540 106431763 106439090 106453000
BOE: 106292637 106328083
THJ: 104798546 104802717 104818862 104827107
CPAP: 110808360
CIT: 102615178
CIC: CICLE_v10005215mg
TCC: 18603766
GRA: 105775486 105776969
GHI: 107916251 107942338
GAB: 108483820 108489452
DZI: 111306984
EGR: 104415295
GMX: 100037469(PDK3) 100779408 100785344 100814079
PVU: PHAVU_009G219900g PHAVU_009G2200001
VRA: 106766729 106778344
VAR: 108319438 108337382
CCAJ: 109804349 109808743
MTR: MTR_2g045490 MTR_7g024460
CAM: 101496392(Pdk) 101500787
LJA: Lj0g3v0267349.1(Lj0g3v0267349.1) Lj4g3v2249050.1(Lj4g3v2249050.1) Lj6g3v1126390.1(Lj6g3v1126390.1)
ADU: 107458797 107479469
AIP: 107611267 107630569
LANG: 109327095 109343612
FVE: 101310404
PPER: 18792242
PMUM: 103323292
PAVI: 110763836
MDM: 103452620 103452727
PXB: 103944686 103950319 103959091
ZJU: 107433361
CSV: 101204312 101213546
CMO: 103483922 103490853
MCHA: 111009461
CMAX: 111479408
CMOS: 111457914
CPEP: 111791452
RCU: 8261345
JCU: 105643624
HBR: 110635268
MESC: 110611773
POP: 7496482
JRE: 108979892 108981587
VVI: 100245923 100266622
SLY: 101249536 101253414
SPEN: 107006756 107007988
SOT: 102580217 102593359
CANN: 107840100 107851511
NTA: 107774290 107779147 107798697 107830420
NSY: 104231883 104246029
NTO: 104114413 104116301
INI: 109175738
SIND: 105156800
OEU: 111371553 111385763
HAN: 110868249 110941261
LSV: 111880400
CCAV: 112527429
DCR: 108193395 108204370
BVG: 104889154
SOE: 110790972
CQI: 110717420 110722049
NNU: 104607140 104611263
PSOM: 113332752 113334808 113347025 113358009
OSA: 4332932 4344039
DOSA: Os03t0370000-01(Os03g0370000) Os07t0637300-01(Os07g0637300)
OBR: 102700877 102704822
BDI: 100822823 100842984
ATS: 109735306(LOC109735306) 109769724(LOC109769724)
SBI: 8063534 8080774
ZMA: 100193944 103638995 103648141 541677(pdlk1) 542603(pdlk2)
SITA: 101756026 101786452
PDA: 103707688 103720053
EGU: 105061503
MUS: 103970414 103971998 103993306
DCT: 110099184
PEQ: 110037896
AOF: 109842738 109848819
ATR: 18430097
SMO: SELMODRAFT_108744 SELMODRAFT_164498 SELMODRAFT_268711 SELMODRAFT_93519
PPP: 112286524 112292562
CRE: CHLREDRAFT_142512(PDK3) CHLREDRAFT_196271(PDK2)
VCN: VOLCADRAFT_54923 VOLCADRAFT_66749
MNG: MNEG_1132 MNEG_2111
OLU: OSTLU_46874
OTA: OT_ostta10g02700
BPG: Bathy11g02780
MIS: MICPUN_108584
MPP: MICPUCDRAFT_50396
CSL: COCSUDRAFT_36801
CVR: CHLNCDRAFT_137427
APRO: F751_4520
CME: CYME_CMR225C
GSL: Gasu_13110
CCP: CHC_T00008298001
AGO: AGOS_AER270W
ERC: Ecym_2505
KLA: KLLA0_F27423g
KMX: KLMA_40335
ZRO: ZYRO0D08052g
PPA: PAS_chr1-1_0202
DHA: DEHA2C13354g
PIC: PICST_90317
PGU: PGUG_05616
SPAA: SPAPADRAFT_59187
LEL: LELG_05335
CAL: CAALFM_CR08860WA(PDK2)
CTP: CTRG_05965
COT: CORT_0D01220
CDU: CD36_34370
CTEN: CANTEDRAFT_115456
YLI: YALI0C21582g
CLU: CLUG_01102
CLUS: A9F13_09g01595
CAUR: QG37_02778
SLB: AWJ20_864(PKP1)
NCR: NCU06760(stk-48)
NTE: NEUTE1DRAFT111129(NEUTE1DRAFT_111129)
SMP: SMAC_06751
PAN: PODANSg6632
TTT: THITE_2124496
MTM: MYCTH_84590
CTHR: CTHT_0013820
MGR: MGG_07161
TMN: UCRPA7_891
SSCK: SPSK_01643
FGR: FGSG_04416
FPU: FPSE_06338
FVR: FVEG_11246
FOX: FOXG_13817
NHE: NECHADRAFT_95779
TRE: TRIREDRAFT_50068
MAW: MAC_01792
MAJ: MAA_05401
CMT: CCM_01061
PLJ: VFPFJ_03816
VAL: VDBG_05287
VDA: VDAG_06937
CFJ: CFIO01_10163
ELA: UCREL1_11271
PFY: PFICI_11255
SSL: SS1G_10371
BFU: BCIN_14g03890
MBE: MBM_04625
PSCO: LY89DRAFT_44651
GLZ: GLAREA_03189
ANI: AN6207.2
AFM: AFUA_2G11900
AOR: AO090026000452
ANG: ANI_1_544024(An02g04000)
AFV: AFLA_134790
ACT: ACLA_070830
NFI: NFIA_087120
PCS: Pc20g14220
PDP: PDIP_31940
CIM: CIMG_05416
CPW: CPC735_065780
PBL: PAAG_00094
PBN: PADG_12250(PADG_07168)
URE: UREG_06303
ABE: ARB_00632
TVE: TRV_05098
AJE: HCAG_03915
PNO: SNOG_15668(SNOG_15666 SNOG_15667)
PTE: PTT_00963
BZE: COCCADRAFT_21753
BSC: COCSADRAFT_78141
BOR: COCMIDRAFT_28292
AALT: CC77DRAFT_304888
ZTR: MYCGRDRAFT_53419
PFJ: MYCFIDRAFT_48088
BCOM: BAUCODRAFT_123897
NPA: UCRNP2_886
TML: GSTUM_00002314001
SPO: SPAC644.11c(pkp1)
CNE: CNA00360 CNI04400
CNB: CNBA0360 CNBH4200
CGI: CGB_B0390C CGB_H5750W
TMS: TREMEDRAFT_27661
TVS: TRAVEDRAFT_31114
DSQ: DICSQDRAFT_157150
PCO: PHACADRAFT_116406
SHS: STEHIDRAFT_93627
HIR: HETIRDRAFT_460407
PSQ: PUNSTDRAFT_135059
ADL: AURDEDRAFT_115237
FME: FOMMEDRAFT_20550
GTR: GLOTRDRAFT_112124
LBC: LACBIDRAFT_190061
MPR: MPER_11803
MRR: Moror_12432 Moror_6956 Moror_9054
CCI: CC1G_15212
SCM: SCHCODRAFT_70039
ABP: AGABI1DRAFT123518(AGABI1DRAFT_123518)
ABV: AGABI2DRAFT179568(AGABI2DRAFT_179568)
CPUT: CONPUDRAFT_145842
SLA: SERLADRAFT_457378
WSE: WALSEDRAFT_61107
WIC: J056_003549
UMA: UMAG_05275
PFP: PFL1_05374
MGL: MGL_2833
PGR: PGTG_17358
MLR: MELLADRAFT_41804
MBR: MONBRDRAFT_31036
SRE: PTSG_00063
ACAN: ACA1_019150
SMIN: v1.2.006537.t1(symbB.v1.2.006537.t1) v1.2.009791.t1(symbB.v1.2.009791.t1) v1.2.017212.t1(symbB.v1.2.017212.t1) v1.2.019767.t1(symbB.v1.2.019767.t1) v1.2.020323.t1(symbB.v1.2.020323.t1) v1.2.020323.t2(symbB.v1.2.020323.t2) v1.2.027845.t1(symbB.v1.2.027845.t1) v1.2.027845.t2(symbB.v1.2.027845.t2) v1.2.033580.t1(symbB.v1.2.033580.t1) v1.2.033580.t2(symbB.v1.2.033580.t2) v1.2.036480.t1(symbB.v1.2.036480.t1) v1.2.036764.t1(symbB.v1.2.036764.t1) v1.2.039627.t1(symbB.v1.2.039627.t1)
PTI: PHATRDRAFT_13123 PHATRDRAFT_15081 PHATRDRAFT_46264 PHATRDRAFT_50961
FCY: FRACYDRAFT_189611 FRACYDRAFT_226529
TPS: THAPSDRAFT_1225 THAPSDRAFT_261233(PDK1_1) THAPSDRAFT_37571
AAF: AURANDRAFT_35155
NGD: NGA_0219900 NGA_2010000
PIF: PITG_00352 PITG_01458 PITG_01461 PITG_02642
PSOJ: PHYSODRAFT_294940 PHYSODRAFT_300151 PHYSODRAFT_314481 PHYSODRAFT_316081 PHYSODRAFT_501168
SPAR: SPRG_01441 SPRG_10674
EHX: EMIHUDRAFT_448217(PDK2) EMIHUDRAFT_461826(PDK4) EMIHUDRAFT_72492(PDK1) EMIHUDRAFT_89159(PDK3)
GTT: GUITHDRAFT_104150 GUITHDRAFT_63012 GUITHDRAFT_63563 GUITHDRAFT_67612
TBR: TB927.1.1000 Tb11.02.2390
TCR: 509875.170 511421.110
LMA: LMJF_20_0280 LMJF_24_0010
LIF: LINJ_20_0310 LINJ_24_0010
LDO: LDBPK_200310 LDBPK_240010
LMI: LMXM_20_0280 LMXM_24_0010
LBZ: LBRM_20_4500 LBRM_24_0010
NGR: NAEGRDRAFT_74828 NAEGRDRAFT_82050
 » show all
Taxonomy
Reference
1  [PMID:4401694]
  Authors
Linn TC, Pelley JW, Pettit FH, Hucho F, Randall DD, Reed LJ.
  Title
-Keto acid dehydrogenase complexes. XV. Purification and properties of the component enzymes of the pyruvate dehydrogenase complexes from bovine kidney and heart.
  Journal
Arch Biochem Biophys 148:327-42 (1972)
DOI:10.1016/0003-9861(72)90151-8
Reference
2  [PMID:3004826]
  Authors
Reed LJ, Damuni Z, Merryfield ML.
  Title
Regulation of mammalian pyruvate and branched-chain alpha-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation.
  Journal
Curr Top Cell Regul 27:41-9 (1985)
Reference
3  [PMID:15629119]
  Authors
Tovar-Mendez A, Hirani TA, Miernyk JA, Randall DD.
  Title
Analysis of the catalytic mechanism of pyruvate dehydrogenase kinase.
  Journal
Arch Biochem Biophys 434:159-68 (2005)
DOI:10.1016/j.abb.2004.10.017
  Sequence
[ath:AT3G06483]
Reference
4  [PMID:15491151]
  Authors
Bao H, Kasten SA, Yan X, Hiromasa Y, Roche TE.
  Title
Pyruvate dehydrogenase kinase isoform 2 activity stimulated by speeding up the rate of dissociation of ADP.
  Journal
Biochemistry 43:13442-51 (2004)
DOI:10.1021/bi0494875
Reference
5  [PMID:12631265]
  Authors
Roche TE, Hiromasa Y, Turkan A, Gong X, Peng T, Yan X, Kasten SA, Bao H, Dong J.
  Title
Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1.
  Journal
Eur J Biochem 270:1050-6 (2003)
DOI:10.1046/j.1432-1033.2003.03468.x
Other DBs
ExplorEnz - The Enzyme Database: 2.7.11.2
IUBMB Enzyme Nomenclature: 2.7.11.2
ExPASy - ENZYME nomenclature database: 2.7.11.2
BRENDA, the Enzyme Database: 2.7.11.2
CAS: 9074-01-5

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Chemical substance (4)   
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3D Structure (25)   
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