KEGG   ENZYME: 2.7.13.1
Entry
EC 2.7.13.1                 Enzyme                                 

Name
protein-histidine pros-kinase;
ATP:protein-L-histidine N-pros-phosphotransferase;
histidine kinase (ambiguous);
histidine protein kinase (ambiguous);
protein histidine kinase (ambiguous);
protein kinase (histidine) (ambiguous);
HK2
Class
Transferases;
Transferring phosphorus-containing groups;
Protein-histidine kinases
Sysname
ATP:protein-L-histidine Npi-phosphotransferase
Reaction(IUBMB)
ATP + protein L-histidine = ADP + protein Npi-phospho-L-histidine [RN:R02625]
Reaction(KEGG)
R02625
Substrate
ATP [CPD:C00002];
protein L-histidine [CPD:C00615]
Product
ADP [CPD:C00008];
protein Npi-phospho-L-histidine [CPD:C04261]
Comment
A number of histones can act as acceptor.
History
EC 2.7.13.1 created 1989 as EC 2.7.3.11, transferred 2005 to EC 2.7.13.1
Reference
1  [PMID:7196259]
  Authors
Fujitaki JM, Fung G, Oh EY, Smith RA.
  Title
Characterization of chemical and enzymatic acid-labile phosphorylation of histone H4 using phosphorus-31 nuclear magnetic resonance.
  Journal
Biochemistry 20:3658-64 (1981)
DOI:10.1021/bi00515a055
Reference
2  [PMID:4066704]
  Authors
Huebner VD, Matthews HR.
  Title
Phosphorylation of histidine in proteins by a nuclear extract of Physarum polycephalum plasmodia.
  Journal
J Biol Chem 260:16106-13 (1985)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.13.1
IUBMB Enzyme Nomenclature: 2.7.13.1
ExPASy - ENZYME nomenclature database: 2.7.13.1
BRENDA, the Enzyme Database: 2.7.13.1
CAS: 99283-67-7

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