KEGG   ENZYME: 2.7.14.1Help
Entry
EC 2.7.14.1                 Enzyme                                 

Name
protein arginine kinase;
McsB
Class
Transferases;
Transferring phosphorus-containing groups;
Protein-arginine kinases
BRITE hierarchy
Sysname
ATP:[protein]-L-arginine Nomega-phosphotransferase
Reaction(IUBMB)
ATP + a [protein]-L-arginine = ADP + a [protein]-Nomega-phospho-L-arginine [RN:R11090]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
protein-L-arginine [CPD:C00613]
Product
ADP [CPD:C00008];
[protein]-Nomega-phospho-L-arginine [CPD:C21101]
Comment
The enzyme, characterized from Gram-positive bacteria, is involved in the regulation of the bacterial stress response.
History
EC 2.7.14.1 created 2014
Orthology
K19405  protein arginine kinase
Genes
BSU: BSU00850(mcsB)
BSR: I33_0115
BSL: A7A1_0121
BSH: BSU6051_00850(mcsB)
BSY: I653_00425
BSUT: BSUB_00113(mcsB)
BSUL: BSUA_00113(mcsB)
BSUS: Q433_00595
BSS: BSUW23_00435(mcsB)
BST: GYO_0111
BSO: BSNT_06376(mcsB)
BSQ: B657_00850(mcsB)
BSX: C663_0087(yacI)
BLI: BL03260(mcsB)
BLD: BLi00103(mcsB)
BLH: BaLi_c01040(mcsB)
BAY: RBAM_001100(mcsB)
BAQ: BACAU_0085(mcsB)
BYA: BANAU_0084(mcsB)
BAMP: B938_00440
BAML: BAM5036_0089(mcsB)
BAMA: RBAU_0093(mcsB)
BAMN: BASU_0091(mcsB)
BAMB: BAPNAU_0084(mcsB)
BAMT: AJ82_00535
BAMY: V529_00870(mcsB)
BAO: BAMF_0084(mcsB)
BAZ: BAMTA208_00430(mcsB)
BQL: LL3_00087(mcsB)
BXH: BAXH7_00091(mcsB)
BQY: MUS_0095(mcsB)
BAMI: KSO_018975
BAMC: U471_00920
BAMF: U722_00560
BATR: TD68_18025
BHA: BH0102
BAN: BA_0079
BAR: GBAA_0079
BAT: BAS0080
BAI: BAA_0096
BANT: A16_00900
BANR: A16R_00900
BANS: BAPAT_0078
BANV: DJ46_4477
BCE: BC0101
BCA: BCE_0080
BCZ: BCE33L0076(karG)
BCQ: BCQ_0094(karG)
BCX: BCA_0109
BAL: BACI_c01060(karG)
BNC: BCN_0080
BCF: bcf_00525
BCER: BCK_07475
BTK: BT9727_0077(karG)
BTL: BALH_0080(karG)
BTT: HD73_0080
BTHI: BTK_00400
BTM: MC28_4793
BTI: BTG_20505
BTW: BF38_1319
BWW: bwei_5584(yacI)
BMYC: DJ92_2688
BMYO: BG05_408
BCL: ABC0120(mcsB)
BPU: BPUM_0070
BPUM: BW16_00580
BPUS: UP12_00575
BPF: BpOF4_08400(mcsB)
BMQ: BMQ_0106(mcsB)
BMD: BMD_0104(mcsB)
BMH: BMWSH_5128(mcsB)
BMEG: BG04_2380
BAG: Bcoa_1195
BCOA: BF29_2386
BJS: MY9_0084
BACW: QR42_00575
BACP: SB24_09190
BACB: OY17_03305
BACO: OXB_0737
BACY: QF06_19500
BACL: BS34A_01190(mcsB)
BALM: BsLM_0093
BEO: BEH_00550
BGY: BGLY_0093(mcsB)
BBEV: BBEV_3278
OIH: OB0092
GKA: GK0077
GTN: GTNG_0077
GGH: GHH_c01010(mcsB)
AFL: Aflv_0076(mcsB)
AAMY: GFC30_104
AXL: AXY_00960(mcsB)
LSP: Bsph_4650
BSE: Bsel_0082
SAU: SA0482
SAV: SAV0524
SAW: SAHV_0521
SAM: MW0479
SAS: SAS0481
SAR: SAR0527
SAC: SACOL0569
SAE: NWMN_0486
SAD: SAAV_0485
SUE: SAOV_0559
SUC: ECTR2_477
SUZ: MS7_0513
SUG: SAPIG0599
SAUA: SAAG_00941
SAUS: SA40_0463
SAUU: SA957_0478
SAUG: SA268_0476
SAUF: X998_0564
SAB: SAB0474
SAUB: C248_0596
SAUM: BN843_5170
SAUC: CA347_539
SAUR: SABB_04416
SAUI: AZ30_02650
SAUD: CH52_03135
SAMS: NI36_02600
SEP: SE0286
SER: SERP0164
SEPP: SEB_00209
SEPS: DP17_1598
SHA: SH2485
SSP: SSP2232
SCA: SCA_0180
SDT: SPSE_2271
SPAS: STP1_1605
SHU: SHYC_11030(mcsB)
SSCH: LH95_10620
SSCZ: RN70_11355
SAGQ: EP23_11130
MCL: MCCL_1887
MCAK: MCCS_24390
LMO: lmo0231
LMQ: LMM7_0253(mscB)
LMS: LMLG_0828
LML: lmo4a_0247(mcsB)
LMP: MUO_01305
LMW: LMOSLCC2755_0229(mcsB)
LMX: LMOSLCC2372_0233(mcsB)
LMZ: LMOSLCC2482_0231(mcsB)
LMON: LMOSLCC2376_0201(mcsB)
LMOC: LMOSLCC5850_0225(mcsB)
LMOS: LMOSLCC7179_0226(mcsB)
LMOO: LMOSLCC2378_0244(mcsB)
LMOY: LMOSLCC2479_0232(mcsB)
LMOT: LMOSLCC2540_0237(mcsB)
LMOA: LMOATCC19117_0239(mcsB)
LMOL: LMOL312_0229(mcsB)
LMOE: BN418_0258
LMOB: BN419_0263
LMOD: LMON_0231
LMOW: AX10_09685
LMOX: AX24_13860
LMOQ: LM6179_0528(mcsB)
LMR: LMR479A_0244(mcsB)
LMOK: CQ02_01305
LMOM: IJ09_09130
LIN: lin0263
LWE: lwe0195
LSG: lse_0217
LIV: LIV_0201
ESI: Exig_0067
EAN: Eab7_0069
BBE: BBR47_01870(mcsB)
PPY: PPE_04311
PPM: PPSC2_22585(mcsB)
PPO: PPM_4485(mcsB)
PPOL: X809_39070
PPOY: RE92_14670
PMW: B2K_35820
PSAB: PSAB_21820
PRI: PRIO_6168
PSWU: SY83_11255
ASOC: CB4_00255
AAC: Aaci_2741
AAD: TC41_3071
BTS: Btus_0121
SIV: SSIL_0184
JEO: JMA_01040
KUR: ASO14_11
CAC: CA_C3190
CAE: SMB_G3226
CAY: CEA_G3194
CPE: CPE2442
CPF: CPF_2752
CPR: CPR_2438
CTC: CTC_02634
CBO: CBO3510
CBA: CLB_3570
CBH: CLC_3459
CBY: CLM_3981
CBL: CLK_2957
CBK: CLL_A0206
CBB: CLD_0991
CBI: CLJ_B3822
CBN: CbC4_0199
CBT: CLH_0204
CBF: CLI_3697
CBM: CBF_3683
CBE: Cbei_0122
CBZ: Cbs_0122
CBEI: LF65_00156
CKL: CKL_0194
CKR: CKR_0155
CPAS: Clopa_4545
CBV: U729_1312
CSQ: CSCA_4255
CTYK: CTK_C29160(mcsB)
AMT: Amet_4513
AOE: Clos_0455
ASF: SFBM_1419
CTH: Cthe_1790
CCE: Ccel_0326
CSD: Clst_0264
CCEL: CCDG5_0488
RBR: RBR_09850
HSC: HVS_12835
CCT: CC1_34430
CPY: Cphy_3462
CSO: CLS_22750
HSD: SD1D_0412
CDF: CD630_00250(mcsB)
PDC: CDIF630_00087(mcsB)
PDF: CD630DERM_00250(mcsB)
CST: CLOST_0159(mcsB)
STH: STH3134
SWO: Swol_2368
SLP: Slip_2269
DSY: DSY0437
DHD: Dhaf_0388
DRM: Dred_0179
DAE: Dtox_0254
PTH: PTH_0282
DAU: Daud_0180
SGY: Sgly_0295
HMO: HM1_1343
TMR: Tmar_2326
SAY: TPY_0275
CTHM: CFE_2707
BPRM: CL3_33690
BPRS: CK3_29620
TTE: TTE2328
THX: Thet_2082
TIT: Thit_2015
CHY: CHY_2349
MTA: Moth_0161
ADG: Adeg_1949
TPZ: Tph_c03710(aTP)
CSC: Csac_2368
ATE: Athe_1826
TOC: Toce_2124
TTM: Tthe_0399
TSH: Tsac_0979
FMA: FMG_0334
APR: Apre_0126
PMIC: NW74_03155
VPR: Vpar_1022
MED: MELS_1353
MHG: MHY_25150
PUF: UFO1_0528
PFT: JBW_03922
LPIL: LIP_3309
CTR: CT_675(karG)
CTD: CTDEC_0675(karG)
CTF: CTDLC_0675(karG)
CTA: CTA_0733(karG)
CTY: CTR_6801(aspC)
CRA: CTO_0733
CTRQ: A363_00725
CTB: CTL0044
CTL: CTLon_0044(aspC)
CTO: CTL2C_349
CTJ: JALI_6801(aspC)
CTZ: CTB_6801(aspC)
CSW: SW2_6871(aspC)
CES: ESW3_6871(aspC_1)
CTRB: BOUR_00720
CTEC: EC599_7011(aspC_1)
CFS: FSW4_6871(aspC_1)
CFW: FSW5_6871(aspC_1)
CTFW: SWFP_7321(aspC_1)
CTCH: O173_03730
CTRI: BN197_6851(aspC_1)
CTRA: BN442_6851(aspC_1)
CTCT: CTW3_03740
CMU: TC_0046
CMUR: Y015_00240
CMX: DNC_00240
CMZ: TAC_00240
CPN: CPn0701(karG)
CPA: CP_0045
CPJ: karG(karG)
CPT: CpB0728
CPM: G5S_0343
CPEC: CPE3_0044
CPEO: CPE1_0044
CPER: CPE2_0044
CHB: G5O_0053
CHR: Cpsi_0501
CPSC: B711_0053
CPSN: B712_0049
CPSB: B595_0053
CPSG: B598_0051
CPSM: B602_0049
CPSI: B599_0051
CPSV: B600_0053
CPSW: B603_0051
CPST: B601_0049
CPSD: BN356_0441
CPSA: AO9_00205
CCA: CCA_00041
CAB: CAB042
CABO: AB7_0451
CFE: CF0964(karG)
PCU: pc1874
PNL: PNK_2244(karG)
PUV: PUV_00340
WCH: wcw_1940(karG)
SNG: SNE_A02460(karG)
OTE: Oter_2677
CAA: Caka_1063
AMU: Amuc_0058
AGL: PYTT_2106
MIN: Minf_0242
RBA: RB7960(yacI)
PSL: Psta_3831
PLM: Plim_0763
TTF: THTE_2030
IPA: Isop_3468
SACI: Sinac_6415
PBOR: BSF38_01445(mcsB)
TDE: TDE2037
TPED: TPE_1966
BRM: Bmur_1083
BPW: WESB_0555
BIP: Bint_0273
TAI: Taci_1403
TLI: Tlie_1402
GAU: GAU_1583
GBA: J421_3216
DTU: Dtur_1481
 » show all
Taxonomy
Reference
1  [PMID:19498169]
  Authors
Fuhrmann J, Schmidt A, Spiess S, Lehner A, Turgay K, Mechtler K, Charpentier E, Clausen T
  Title
McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR.
  Journal
Science 324:1323-7 (2009)
DOI:10.1126/science.1170088
Reference
2  [PMID:22517742]
  Authors
Elsholz AK, Turgay K, Michalik S, Hessling B, Gronau K, Oertel D, Mader U, Bernhardt J, Becher D, Hecker M, Gerth U
  Title
Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis.
  Journal
Proc Natl Acad Sci U S A 109:7451-6 (2012)
DOI:10.1073/pnas.1117483109
  Sequence
[bsu:BSU00850]
Reference
3  [PMID:24263382]
  Authors
Schmidt A, Trentini DB, Spiess S, Fuhrmann J, Ammerer G, Mechtler K, Clausen T
  Title
Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response.
  Journal
Mol Cell Proteomics 13:537-50 (2014)
DOI:10.1074/mcp.M113.032292
  Sequence
[bsu:BSU00850]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.14.1
IUBMB Enzyme Nomenclature: 2.7.14.1
ExPASy - ENZYME nomenclature database: 2.7.14.1
BRENDA, the Enzyme Database: 2.7.14.1

DBGET integrated database retrieval system