KEGG   ENZYME: 2.7.2.16Help
Entry
EC 2.7.2.16                 Enzyme                                 

Name
2-phosphoglycerate kinase;
pgk2 (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a carboxy group as acceptor
BRITE hierarchy
Sysname
ATP:2-phosphoglycerate 3-phosphotransferase
Reaction(IUBMB)
ATP + 2-phospho-D-glycerate = ADP + 2,3-diphospho-D-glycerate [RN:R02664]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
2-phospho-D-glycerate [CPD:C00631]
Product
ADP [CPD:C00008];
2,3-diphospho-D-glycerate
Comment
The enzyme, found in a number of methanogenic archaeal genera, is involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant. Activity is stimulated by potassium ions.
History
EC 2.7.2.16 created 2019
Orthology
K05715  2-phosphoglycerate kinase
Genes
ATH: AT3G45090
FRA: Francci3_2383
FRI: FraEuI1c_1617
RXY: Rxyl_0777
RRD: RradSPS_0650
DRA: DR_1514
DGE: Dgeo_1765
DDR: Deide_06610
DMR: Deima_2799
DPT: Deipr_0721
DFC: DFI_08620
TTH: TT_C0121
TTJ: TTHA0495
TAQ: TO73_1841
MJA: MJ_1482
MMP: MMP1431(2pgk)
MMD: GYY_07990
MMAK: MMKA1_16550(pgk2)
MMAO: MMOS7_15380(pgk2)
MMAD: MMJJ_14080
MAE: Maeo_0251
MVO: Mvol_1490
MTH: MTH_1883
MMG: MTBMA_c04540(pgk1)
METC: MTCT_1721
MWO: MWSIV6_0414(pgk2_3)
METE: tca_01819
MST: Msp_0443(pgk2-1)
MRU: mru_0822(pgk2B)
MSI: Msm_0791
MEB: Abm4_1302(pgk2)
MMIL: sm9_1712(pgk2B)
MEYE: TL18_07615
MOL: YLM1_0409
METH: MBMB1_1270(pgk2)
MFC: BRM9_0486(pgk2B)
MFI: DSM1535_0467(pgk2)
MCUB: MCBB_1485(pgk2_1)
MFV: Mfer_0247
MKA: MK0868
PFU: PF0078
PFI: PFC_07810
PHO: PH0149(PH0149)
PAB: PAB2253
PYN: PNA2_0684
PYS: Py04_0159
TKO: TK1038
TON: TON_0742
TGA: TGAM_0724
TSI: TSIB_0159
THE: GQS_01215
THA: TAM4_889
THM: CL1_1941
TLT: OCC_11507
TNU: BD01_0985
TEU: TEU_10720
PPAC: PAP_01540
 » show all
Taxonomy
Reference
1  [PMID:2226838]
  Authors
Lehmacher A, Vogt AB, Hensel R
  Title
Biosynthesis of cyclic 2,3-diphosphoglycerate. Isolation and characterization of  2-phosphoglycerate kinase and cyclic 2,3-diphosphoglycerate synthetase from Methanothermus fervidus.
  Journal
FEBS Lett 272:94-8 (1990)
DOI:10.1016/0014-5793(90)80456-s
Reference
2  [PMID:8159166]
  Authors
Lehmacher A, Hensel R
  Title
Cloning, sequencing and expression of the gene encoding 2-phosphoglycerate kinase from Methanothermus fervidus.
  Journal
Mol Gen Genet 242:163-8 (1994)
DOI:10.1007/bf00391009
  Sequence
[mfv:Mfer_0247]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.2.16
IUBMB Enzyme Nomenclature: 2.7.2.16
ExPASy - ENZYME nomenclature database: 2.7.2.16
BRENDA, the Enzyme Database: 2.7.2.16

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