| Entry |
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| Name |
2-phosphoglycerate kinase;
pgk2 (gene name)
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a carboxy group as acceptor
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| Sysname |
ATP:2-phosphoglycerate 3-phosphotransferase
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| Reaction(IUBMB) |
ATP + 2-phospho-D-glycerate = ADP + 2,3-diphospho-D-glycerate [RN: R02664]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme, found in a number of methanogenic archaeal genera, is involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant. Activity is stimulated by potassium ions.
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| History |
EC 2.7.2.16 created 2019
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| Orthology |
| K05715 | 2-phosphoglycerate kinase |
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| Genes |
» show all
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| Reference |
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| Authors |
Lehmacher A, Vogt AB, Hensel R |
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| Title |
Biosynthesis of cyclic 2,3-diphosphoglycerate. Isolation and characterization of 2-phosphoglycerate kinase and cyclic 2,3-diphosphoglycerate synthetase from Methanothermus fervidus. |
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| Journal |
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| Reference |
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| Authors |
Lehmacher A, Hensel R |
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| Title |
Cloning, sequencing and expression of the gene encoding 2-phosphoglycerate kinase from Methanothermus fervidus. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.7.2.16 |
| ExPASy - ENZYME nomenclature database: | 2.7.2.16 |
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