KEGG   ENZYME: 2.7.4.4Help
Entry
EC 2.7.4.4                  Enzyme                                 

Name
nucleoside-phosphate kinase;
NMP-kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor
BRITE hierarchy
Sysname
ATP:nucleoside-phosphate phosphotransferase
Reaction(IUBMB)
ATP + nucleoside phosphate = ADP + nucleoside diphosphate [RN:R00334]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
nucleoside phosphate [CPD:C01329]
Product
ADP [CPD:C00008];
nucleoside diphosphate [CPD:C00454]
Comment
Many nucleotides can act as acceptors; other nucleoside triphosphates can act instead of ATP.
History
EC 2.7.4.4 created 1961
Reference
1  [PMID:13363863]
  Authors
AYENGAR P, GIBSON DM, SANADI DR.
  Title
Transphosphorylations between nucleoside phosphates.
  Journal
Biochim Biophys Acta 21:86-91 (1956)
DOI:10.1016/0006-3002(56)90096-8
Reference
2  [PMID:14401179]
  Authors
HEPPEL LA, STROMINGER JL, MAXWELL ES.
  Title
Nucleoside monophosphate kinases. II. Transphosphorylation betweeen adenosine monophosphate and nucleoside triphosphates.
  Journal
Biochim Biophys Acta 32:422-30 (1959)
Reference
3  [PMID:14392176]
  Authors
LIEBERMAN I, KORNBERG A, SIMMS ES.
  Title
Enzymatic synthesis of nucleoside diphosphates and triphosphates.
  Journal
J Biol Chem 215:429-40 (1955)
Reference
4
  Authors
Noda, L.
  Title
Nucleoside triphosphate-nucleoside monophosphokinases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 6, Academic Press, New York, 1962, p. 139-149.
Other DBs
ExplorEnz - The Enzyme Database: 2.7.4.4
IUBMB Enzyme Nomenclature: 2.7.4.4
ExPASy - ENZYME nomenclature database: 2.7.4.4
BRENDA, the Enzyme Database: 2.7.4.4
CAS: 9026-50-0

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