KEGG   ENZYME: 2.7.7.103Help
Entry
EC 2.7.7.103                Enzyme                                 

Name
L-glutamine-phosphate cytidylyltransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname
CTP:phosphoglutamine cytidylyltransferase
Reaction(IUBMB)
CTP + N5-phospho-L-glutamine = diphosphate + N5-(cytidine 5'-diphosphoramidyl)-L-glutamine [RN:R12247]
Reaction(KEGG)
Substrate
CTP [CPD:C00063];
N5-phospho-L-glutamine [CPD:C21785]
Product
diphosphate [CPD:C00013];
N5-(cytidine 5'-diphosphoramidyl)-L-glutamine [CPD:C22033]
Comment
The enzyme, characterized from the bacterium Campylobacter jejuni, is involved in formation of a unique O-methyl phosphoramidate modification on specific sugar residues within the bacterium's capsular polysaccharides.
History
EC 2.7.7.103 created 2018
Orthology
K01009  L-glutamine-phosphate cytidylyltransferase
Genes
PLQ: AA042_05470
MHC: MARHY0659
THO: SP60_02245
HHE: HH_1439
HCP: HCN_1063
HCB: HCBAA847_0911
HBL: XJ32_09985
HAD: CDV25_08820
WSU: WS2178
CJE: Cj1416c
CJU: C8J_0637
CJI: CJSA_1347
CJM: CJM1_0655
CJEJ: N564_01413
CJEU: N565_01453
CJEN: N755_01450
CJEI: N135_01505
CJER: H730_08035
CJY: QZ67_01551(spsI)
CJQ: UC78_1358
CFZ: CSG_17660
CLA: CLA_0316
CCF: YSQ_05950
CCY: YSS_03090
CCOI: YSU_05600
CIS: CINS_0306
CCUN: CCUN_1303
NCT: NMSP_0153
 » show all
Taxonomy
Reference
1  [PMID:29023101]
  Authors
Taylor ZW, Brown HA, Holden HM, Raushel FM
  Title
Biosynthesis of Nucleoside Diphosphoramidates in Campylobacter jejuni.
  Journal
Biochemistry 56:6079-6082 (2017)
DOI:10.1021/acs.biochem.7b00905
  Sequence
[cje:Cj1416c]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.7.103
IUBMB Enzyme Nomenclature: 2.7.7.103
ExPASy - ENZYME nomenclature database: 2.7.7.103
BRENDA, the Enzyme Database: 2.7.7.103

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