Entry
Name
L-glutamine-phosphate cytidylyltransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname
CTP:phosphoglutamine cytidylyltransferase
Reaction(IUBMB)
CTP + N5-phospho-L-glutamine = diphosphate + N5-(cytidine 5'-diphosphoramidyl)-L-glutamine [RN:
R12247 ]
Reaction(KEGG)
Substrate
Product
diphosphate [CPD:
C00013 ];
N5-(cytidine 5'-diphosphoramidyl)-L-glutamine [CPD:
C22033 ]
Comment
The enzyme, characterized from the bacterium Campylobacter jejuni, is involved in formation of a unique O-methyl phosphoramidate modification on specific sugar residues within the bacterium's capsular polysaccharides.
History
EC 2.7.7.103 created 2018
Orthology
K01009 L-glutamine-phosphate cytidylyltransferase
Genes
HHK : HH1059_03550 HH1059_03860
HCL : NCTC13205_00567(gtaB)
HPUL : NCTC13154_00546(gtaB_1)
» show all
Taxonomy
Reference
Authors
Taylor ZW, Brown HA, Holden HM, Raushel FM
Title
Biosynthesis of Nucleoside Diphosphoramidates in Campylobacter jejuni.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.7.7.103