KEGG   ENZYME: 2.7.7.47Help
Entry
EC 2.7.7.47                 Enzyme                                 

Name
streptomycin 3''-adenylyltransferase;
streptomycin adenylate synthetase;
streptomycin adenyltransferase;
streptomycin adenylylase;
streptomycin adenylyltransferase;
streptomycin-spectinomycin adenylyltransferase;
AAD (3'');
aminoglycoside 3''-adenylyltransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname
ATP:streptomycin 3''-adenylyltransferase
Reaction(IUBMB)
ATP + streptomycin = diphosphate + 3''-adenylylstreptomycin [RN:R02226]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
streptomycin [CPD:C00413]
Product
diphosphate [CPD:C00013];
3''-adenylylstreptomycin [CPD:C03462]
Comment
Also acts on spectinomycin.
History
EC 2.7.7.47 created 1976
Orthology
K00984  streptomycin 3"-adenylyltransferase
Genes
EUN: pUMNK88_130(aadA) pUMNK88_133(aadA2)
ECV: APECO1_O1R89(aadA)
ECM: EcSMS35_A0135(aadA)
EUM: ECUMN_4816(aadA)
ELO: EC042_4093(aadA1)
ELN: NRG857_30102
ECOS: EC958_A0109(aadA5)
STY: STY1857(aadA)
STT: t1142(aadA)
SEX: STBHUCCB_12250
STM: STM1264(aadA)
SEO: STM14_1525(aadA)
SEY: SL1344_1199(aadA)
SEJ: STMUK_1231(aadA)
SEB: STM474_1265(aadA)
SEF: UMN798_1312(aadA)
SENR: STMDT2_11961(aadA)
SPT: SPA1582(aadA)
SEK: SSPA1470
SEI: SPC_2479(aadA)
SEC: SCH_032(aadA2) SCH_051(aadA2) SCH_053(aadA2) SCH_1275(aadA)
SHB: SU5_01885
SENS: Q786_08935
SEG: SG1860(aadA)
SEL: SPUL_1067(aadA)
SEGA: SPUCDC_1067(aadA)
SET: SEN1788(aadA)
SENA: AU38_09260
SENO: AU37_09265
SENV: AU39_09270
SENQ: AU40_10340
SENL: IY59_09475
SEEP: I137_04900
SENE: IA1_06235
SBG: SBG_1109(aadA)
SBZ: A464_1205
SFN: SFy_1440
SFS: SFyv_1489
SSN: SSON_3896(aadA)
KPN: KPN_pKPN4p07059(aadA)
KPJ: N559_5186
KPX: PMK1_ndm00221(ant1)
EAR: CCG28765
LEI: C2U54_25010(aadA1) C2U54_26545(aadA1)
LEH: C3F35_26160(aadA1)
SMAF: D781_3902
SMAR: SM39_pSMC1_34(aadA)
SERF: L085_10150
PSI: S70_21070
PSX: DR96_3112
MMK: MU9_2178
PMP: Pmu_03420(aadA25)
PNC: NCGM2_1759(aadA1)
PAEB: NCGM1900_3708(aadA6)
PMY: Pmen_2178
PMK: MDS_2542
PPUH: B479_26984
PSA: PST_2171
ACB: A1S_0131
ABM: ABSDF0145
ABY: ABAYE3570(aadA1) ABAYE3618(aadA1) ABAYE3739
ABN: AB57_0171 AB57_0293(aadA1)
ABD: ABTW07_0156 ABTW07_3885(aadA1) ABTW07_3901(aadA1)
ABH: M3Q_2662
ABAD: ABD1_01350(aadA)
ABAZ: P795_16505
ABAU: IX87_15250
ABAA: IX88_02960
ACC: BDGL_003056(ant)
LPP: plpp0092
LPC: LPC_2300
LOK: Loa_01991
LCD: clem_03050(ant1)
APAC: S7S_01185
ASA: ASA_P4G100(aadA)
CTI: RALTA_B0831(aadA)
BCJ: BCAM1013a
BCEO: I35_4932
BAM: Bamb_3372
BCT: GEM_4783
BCED: DM42_4074
BCON: NL30_07300
BTEI: WS51_03320
BSEM: WJ12_25325
BPA: BPP1010(aadA4)
BPAR: BN117_3644(aadA4)
BBR: BB1224(aadA4)
BBM: BN115_1180(aadA4)
BBH: BN112_2235(aadA4)
BBX: BBS798_1186(aadA4)
BTRM: SAMEA390648702365(aadA4)
AXY: AXYL_03722(aadA)
HYB: Q5W_09230
MELA: C6568_16815(aadA1)
MMS: mma_1582(aadA4)
DDS: Ddes_1735
MXA: MXAN_1698
SMD: Smed_5877
RIR: BN877_II1271(aadA)
FIL: BN1229_v1_2349(ant)
FIY: BN1229_v1_2350(ant)
PDE: Pden_4803
VPN: A21D_03902(ant1)
PMW: B2K_23630
PRI: PRIO_2416
LPJ: JDM1_0099
LPZ: Lp16_0091
LRH: LGG_00494
LRG: LRHM_0478
LRA: LRHK_505
EFA: EF1076
EFS: EFS1_0902
EFQ: DR75_152
THL: TEH_23880
CBI: CLJ_B3653
CKL: CKL_2614
CKR: CKR_2315
AOE: Clos_2446
CCE: Ccel_2808
BHU: bhn_I0831
CPY: Cphy_3186
DSY: DSY4374
DHD: Dhaf_0956
LPIL: LIP_2795
SCO: SCO4355(SCD19.10)
SALB: XNR_3225
SRW: TUE45_pSRc_0186(ant1)
SFK: KY5_0260c
BCV: Bcav_0454
CFI: Celf_1083
MPH: MLP_15410
AOI: AORI_3389
SESP: BN6_11520
KAL: KALB_1235
SYO: C7I86_08920(aadA1)
RCA: Rcas_0978
PPAC: PAP_07650
 » show all
Taxonomy
Reference
1  [PMID:4887506]
  Authors
Harwood JH, Smith DH.
  Title
Resistance factor-mediated streptomycin resistance.
  Journal
J Bacteriol 97:1262-71 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.7.47
IUBMB Enzyme Nomenclature: 2.7.7.47
ExPASy - ENZYME nomenclature database: 2.7.7.47
BRENDA, the Enzyme Database: 2.7.7.47
CAS: 52660-23-8

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